CGP 37849 (BioDeep_00000830593)
代谢物信息卡片
化学式: C6H12NO5P (209.0453072)
中文名称: (E)-(+/-)-2-氨基-4-甲基-5-磷-3-戊烯酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=CC(C(=O)O)N)CP(=O)(O)O
InChI: InChI=1S/C6H12NO5P/c1-4(3-13(10,11)12)2-5(7)6(8)9/h2,5H,3,7H2,1H3,(H,8,9)(H2,10,11,12)/b4-2+
描述信息
D018377 - Neurotransmitter Agents > D018683 - Excitatory Amino Acid Agents > D018691 - Excitatory Amino Acid Antagonists
D002491 - Central Nervous System Agents > D000927 - Anticonvulsants
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- An Torremans, Bart Marescau, Debby Van Dam, Chris Van Ginneken, Frans Van Meir, Pierre-Paul Van Bogaert, Rudi D'Hooge, Jan de Vente, Peter Paul De Deyn. GSA: behavioral, histological, electrophysiological and neurochemical effects.
Physiology & behavior.
2005 Feb; 84(2):251-64. doi:
10.1016/j.physbeh.2004.12.001. [PMID: 15708777] - Rudi D'Hooge, Gerda Van de Vijver, Pierre-Paul Van Bogaert, Bart Marescau, Raymond Vanholder, Peter P De Deyn. Involvement of voltage- and ligand-gated Ca2+ channels in the neuroexcitatory and synergistic effects of putative uremic neurotoxins.
Kidney international.
2003 May; 63(5):1764-75. doi:
10.1046/j.1523-1755.2003.00912.x. [PMID: 12675852] - T Ravizza, D Moneta, B Bottazzi, G Peri, C Garlanda, E Hirsch, G J Richards, A Mantovani, A Vezzani. Dynamic induction of the long pentraxin PTX3 in the CNS after limbic seizures: evidence for a protective role in seizure-induced neurodegeneration.
Neuroscience.
2001; 105(1):43-53. doi:
10.1016/s0306-4522(01)00177-4. [PMID: 11483299] - C Mondadori, J Borkowski, C Gentsch. The memory-facilitating effects of the competitive NMDA-receptor antagonist CGP 37849 are steroid-sensitive, whereas its memory-impairing effects are not.
Psychopharmacology.
1996 Apr; 124(4):380-3. doi:
10.1007/bf02247445. [PMID: 8739555] - V Kumar, G A Lincoln, D J Tortonese. Effects of excitatory amino acid receptor agonists and antagonists on the secretion of melatonin, luteinizing hormone and prolactin in the ram.
Journal of neuroendocrinology.
1993 Dec; 5(6):649-54. doi:
10.1111/j.1365-2826.1993.tb00535.x. [PMID: 8680437] - T Pietrasiewicz, G Czechowska, M Dziki, W A Turski, Z Kleinrok, S J Czuczwar. Competitive NMDA receptor antagonists enhance the antielectroshock activity of various antiepileptics.
European journal of pharmacology.
1993 Nov; 250(1):1-7. doi:
10.1016/0014-2999(93)90613-m. [PMID: 7907019] - G Czechowska, M Dziki, T Pietrasiewicz, Z Kleinrok, W A Turski, S J Czuczwar. Competitive antagonists of NMDA receptors, CGP 37849 and CGP 39551, enhance the anticonvulsant activity of valproate against electroconvulsions in mice.
European journal of pharmacology.
1993 Feb; 232(1):59-64. doi:
10.1016/0014-2999(93)90728-z. [PMID: 8096188] - F R Derubertis, T Zenser. Activation of murine lymphocytes by cyclic guanosine 3',5'-monophosphate: specificity and role in mitogen activity.
Biochimica et biophysica acta.
1976 Mar; 428(1):91-103. doi:
10.1016/0304-4165(76)90111-2. [PMID: 4115]