AMG 9810 (BioDeep_00000830592)

   


代谢物信息卡片


(2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propenamide

化学式: C21H23NO3 (337.16778480000005)
中文名称: AMG9810
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)(C)C1=CC=C(C=C1)C=CC(=O)NC2=CC3=C(C=C2)OCCO3
InChI: InChI=1S/C21H23NO3/c1-21(2,3)16-7-4-15(5-8-16)6-11-20(23)22-17-9-10-18-19(14-17)25-13-12-24-18/h4-11,14H,12-13H2,1-3H3,(H,22,23)/b11-6+



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Lisa Wright, Daniel Baptista-Hon, Fiona Bull, Faith Dalgaty, Michael Gallacher, Sally H Ibbotson, Tim G Hales. Menthol reduces phototoxicity pain in a mouse model of photodynamic therapy. Pain. 2018 02; 159(2):284-297. doi: 10.1097/j.pain.0000000000001096. [PMID: 29194091]
  • Natsuhiko Takata, Yohei Ohshima, Miki Suzuki-Karasaki, Yukihiro Yoshida, Yasuaki Tokuhashi, Yoshihiro Suzuki-Karasaki. Mitochondrial Ca2+ removal amplifies TRAIL cytotoxicity toward apoptosis-resistant tumor cells via promotion of multiple cell death modalities. International journal of oncology. 2017 Jul; 51(1):193-203. doi: 10.3892/ijo.2017.4020. [PMID: 28560396]
  • Olga A Sergeeva, Roberto De Luca, Karolina Mazur, Aissa N Chepkova, Helmut L Haas, Andreas Bauer. N-oleoyldopamine modulates activity of midbrain dopaminergic neurons through multiple mechanisms. Neuropharmacology. 2017 06; 119(?):111-122. doi: 10.1016/j.neuropharm.2017.04.011. [PMID: 28400256]
  • Lawrence M Carey, Richard A Slivicki, Emma Leishman, Ben Cornett, Ken Mackie, Heather Bradshaw, Andrea G Hohmann. A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase. Molecular pain. 2016; 12(?):. doi: 10.1177/1744806916649192. [PMID: 27178246]
  • Deise Prehs Montrucchio, Marina Machado Córdova, Adair Roberto Soares Santos. Plant derived aporphinic alkaloid S-(+)-dicentrine induces antinociceptive effect in both acute and chronic inflammatory pain models: evidence for a role of TRPA1 channels. PloS one. 2013; 8(7):e67730. doi: 10.1371/journal.pone.0067730. [PMID: 23861794]
  • Chul-Kyu Park, Ning Lü, Zhen-Zhong Xu, Tong Liu, Charles N Serhan, Ru-Rong Ji. Resolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 Oct; 31(42):15072-85. doi: 10.1523/jneurosci.2443-11.2011. [PMID: 22016541]
  • Joris Vriens, Grzegorz Owsianik, Thomas Hofmann, Stephan E Philipp, Julia Stab, Xiaodi Chen, Melissa Benoit, Fenqin Xue, Annelies Janssens, Sara Kerselaers, Johannes Oberwinkler, Rudi Vennekens, Thomas Gudermann, Bernd Nilius, Thomas Voets. TRPM3 is a nociceptor channel involved in the detection of noxious heat. Neuron. 2011 May; 70(3):482-94. doi: 10.1016/j.neuron.2011.02.051. [PMID: 21555074]
  • Jin Y Ro, Jong-Seok Lee, Youping Zhang. Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia. Pain. 2009 Aug; 144(3):270-277. doi: 10.1016/j.pain.2009.04.021. [PMID: 19464796]