Dopexamine hydrochloride (BioDeep_00000829942)

   


代谢物信息卡片


Dopexamine hydrochloride

化学式: C22H34Cl2N2O2 (428.1997204)
中文名称: 盐酸多巴沙明
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)CCNCCCCCCNCCC2=CC(=C(C=C2)O)O.Cl.Cl
InChI: 2*1H

描述信息

D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018491 - Dopamine Agonists
C78272 - Agent Affecting Nervous System > C66884 - Dopamine Agonist
D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
Dopexamine hydrochloride is a β2 adrenergic receptor agonist.

同义名列表

2 个代谢物同义名

Dopexamine hydrochloride; FPL60278AR



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

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WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • Mansoor N Bangash, Nimesh S A Patel, Elisa Benetti, Massimo Collino, Charles J Hinds, Christoph Thiemermann, Rupert M Pearse. Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow. Critical care (London, England). 2013 Mar; 17(2):R57. doi: 10.1186/cc12585. [PMID: 23531318]
  • Rajeshwara K P Adluri, Arvind V Singh, Julian Skoyles, Adrian Robins, Joan Parton, Mya Baker, Ian M Mitchell. The effect of fenoldopam and dopexamine on cytokine and endotoxin release following on-pump coronary artery bypass grafting: a prospective randomized double-blind trial. The heart surgery forum. 2010 Dec; 13(6):E353-61. doi: 10.1532/hsf98.20101073. [PMID: 21169142]
  • Christian Probst, Frank Hildebrand, Martijn van Griensven, Hellmut Baur, Lutz Mahlke, Christian Krettek, Hans-Christoph Pape, Martin Rolf Wolfgang Grotz. Is dopexamine superior to dopamine in the treatment of multiple trauma patients--a prospective, double-blind, randomised study. Injury. 2010 May; 41(5):499-505. doi: 10.1016/j.injury.2009.06.018. [PMID: 19595327]
  • Shaman Jhanji, Amanda Vivian-Smith, Susana Lucena-Amaro, David Watson, Charles J Hinds, Rupert M Pearse. Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial. Critical care (London, England). 2010; 14(4):R151. doi: 10.1186/cc9220. [PMID: 20698956]
  • N E El Mokhtari, A Arlt, A Meissner, M Lins. Inotropic therapy for cardiac low output syndrome: comparison of hemodynamic effects of dopamine/dobutamine versus dopamine/dopexamine. European journal of medical research. 2008 Oct; 13(10):459-63. doi: NULL. [PMID: 19008172]
  • Nour Eddine El Mokhtari, A Arlt, A Meissner, M Lins. Inotropic therapy for cardiac low output syndrome: comparison of hemodynamic effects of dopamine/dobutamine versus dopamine/dopexamine. European journal of medical research. 2007 Nov; 12(11):563-7. doi: NULL. [PMID: 18024265]
  • Martin Schmoelz, Gustav Schelling, Martin Dunker, Michael Irlbeck. Comparison of systemic and renal effects of dopexamine and dopamine in norepinephrine-treated septic shock. Journal of cardiothoracic and vascular anesthesia. 2006 Apr; 20(2):173-8. doi: 10.1053/j.jvca.2005.10.016. [PMID: 16616656]
  • J H Laake, J F Bugge. Prevention of acute renal failure--first do no harm!. Acta anaesthesiologica Scandinavica. 2006 Feb; 50(2):255-6; author reply 256. doi: 10.1111/j.1399-6576.2006.00930.x. [PMID: 16430553]
  • Jurgen Birnbaum, Edda Klotz, Claudia D Spies, Bjorn Lorenz, Patrick Stuebs, Ortrud Vargas Hein, Matthias Grundling, Dragan Pavlovic, Taras Usichenko, Michael Wendt, Wolfgang J Kox, Christian Lehmann. Effects of dopexamine on the intestinal microvascular blood flow and leukocyte activation in a sepsis model in rats. Critical care (London, England). 2006; 10(4):R117. doi: 10.1186/cc5011. [PMID: 16893450]
  • G Kostopanagiotou, A Pandazi, I Andreadou, A Doufas, I Chondroudaki, T Kotsis, D Rizos, C Costopanagiotou, V Smyrniotis. Effects of dopexamine on lipid peroxidation during aortic surgery in pigs: comparison with dopamine. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 2005 Dec; 30(6):648-53. doi: 10.1016/j.ejvs.2005.06.029. [PMID: 16102983]
  • J W Sear. Kidney dysfunction in the postoperative period. British journal of anaesthesia. 2005 Jul; 95(1):20-32. doi: 10.1093/bja/aei018. [PMID: 15531622]
  • Thomas Schilling, Matthias Gründling, Christof M Strang, Klaus-Uwe Möritz, Werner Siegmund, Thomas Hachenberg. Effects of dopexamine, dobutamine or dopamine on prolactin and thyreotropin serum concentrations in high-risk surgical patients. Intensive care medicine. 2004 Jun; 30(6):1127-33. doi: 10.1007/s00134-004-2279-4. [PMID: 15138671]
  • Luzius B Hiltebrand, Vladimir Krejci, Gisli H Sigurdsson. Effects of dopamine, dobutamine, and dopexamine on microcirculatory blood flow in the gastrointestinal tract during sepsis and anesthesia. Anesthesiology. 2004 May; 100(5):1188-97. doi: 10.1097/00000542-200405000-00022. [PMID: 15114217]
  • Wolfgang Geisser, Josef Vogt, Ulrich Wachter, Hannes Hofbauer, Michael Georgieff, Hermann Ensinger. Effects of dopexamine in comparison with fenoterol on carbohydrate, fat and protein metabolism in healthy volunteers. Intensive care medicine. 2004 Apr; 30(4):702-8. doi: 10.1007/s00134-003-2124-1. [PMID: 14985966]
  • B B Yelken, E S Görenek, K Uzuner, Y Aydin, C Elmas. Effects of dopexamine on rat cardiorenal functions during lipopolysaccharide-induced experimental sepsis. The Journal of international medical research. 2004 Mar; 32(2):109-17. doi: 10.1177/147323000403200202. [PMID: 15080013]
  • J Birnbaum, C Lehmann, K Taymoorian, D Krausch, H Wauer, M Gründling, C Spies, W J Kox. [The effect of dopexamine and iloprost on plasma disappearance rate of indocyanine green in patients in septic shock]. Der Anaesthesist. 2003 Nov; 52(11):1014-9. doi: 10.1007/s00101-003-0580-1. [PMID: 14992087]
  • George Asimakopoulos, Terence Gourlay. A review of anti-inflammatory strategies in cardiac surgery. Perfusion. 2003 Mar; 18 Suppl 1(?):7-12. doi: 10.1191/0267659103pf623oa. [PMID: 12708760]
  • Catherine J Ralph, Suzie J Tanser, Peter D Macnaughton, David G Sinclair. A randomised controlled trial investigating the effects of dopexamine on gastrointestinal function and organ dysfunction in the critically ill. Intensive care medicine. 2002 Jul; 28(7):884-90. doi: 10.1007/s00134-002-1322-6. [PMID: 12122526]
  • T Schilling, C M Strang, L Wilhelm, K U Möritz, W Siegmund, M Gründling, T Hachenberg. Endocrine effects of dopexamine vs. dopamine in high-risk surgical patients. Intensive care medicine. 2001 Dec; 27(12):1908-15. doi: 10.1007/s00134-001-1144-y. [PMID: 11797027]
  • E Alhan, U Küçüktülü, C Erçin, O Deger, R Cicek. Effects of dopexamine on acute necrotising pancreatitis in rats. The European journal of surgery = Acta chirurgica. 2001 Oct; 167(10):761-6. doi: 10.1080/11024150152707743. [PMID: 11775728]
  • M G Dehne, T F Klein, J Mühling, A Sablotzki, C Osmer, G Hempelmann. Impairment of renal function after cardiopulmonary bypass is not influenced by dopexamine. Renal failure. 2001 Mar; 23(2):217-30. doi: 10.1081/jdi-100103493. [PMID: 11417953]
  • S N Piper, J Boldt, C C Schmidt, C Brosch, W H Maleck, C Berchtold. Influence of dopexamine on hemodynamics, intramucosal pH, and regulators of the macrocirculation and microcirculation in patients undergoing abdominal aortic surgery. Journal of cardiothoracic and vascular anesthesia. 2000 Jun; 14(3):281-7. doi: 10.1053/cr.2000.5853. [PMID: 10890482]
  • G Marx, M Leuwer, M Höltje, A Bornscheuer, H Herrmann, K H Mahr, B Vangerow, J Heine, S Piepenbrock, H Rueckoldt. Low-dose dopexamine in patients undergoing hemihepatectomy: an evaluation of effects on reduction of hepatic dysfunction and ischaemic liver injury. Acta anaesthesiologica Scandinavica. 2000 Apr; 44(4):410-6. doi: 10.1034/j.1399-6576.2000.440409.x. [PMID: 10757573]
  • K Kirchhoff, M Leuwer, P Thum, A Bornscheuer, S Piepenbrock. Different effects of dopamine and dopexamine on the isolated perfused rat kidney. British journal of anaesthesia. 1999 Dec; 83(6):898-902. doi: 10.1093/bja/83.6.898. [PMID: 10700790]
  • B Levy, L Nace, P E Bollaert, B Dousset, J P Mallie, A Larcan. Comparison of systemic and regional effects of dobutamine and dopexamine in norepinephrine-treated septic shock. Intensive care medicine. 1999 Sep; 25(9):942-8. doi: 10.1007/s001340050986. [PMID: 10501749]
  • M Blunt, P Young, S Ridley. A comparison of the effects of dopexamine and prostacyclin in systemic inflammatory response syndrome. Anaesthesia. 1999 Apr; 54(4):313-9. doi: 10.1046/j.1365-2044.1999.00748.x. [PMID: 10455827]
  • J Boldt, M Papsdorf, S Piper, W Padberg, G Hempelmann. Retracted: Influence of dopexamine hydrochloride on haemodynamics and regulators of circulation in patients undergoing major abdominal surgery. Acta anaesthesiologica Scandinavica. 1998 09; 42(8):941-7. doi: 10.1111/j.1399-6576.1998.tb05354.x. [PMID: 9773139]
  • R Bellomo, L Cole, C Ronco. Hemodynamic support and the role of dopamine. Kidney international. Supplement. 1998 May; 66(?):S71-4. doi: NULL. [PMID: 9573578]
  • L Bindl. Gastrointestinal permeability following cardiopulmonary bypass. Intensive care medicine. 1998 Mar; 24(3):280. doi: 10.1007/pl00012681. [PMID: 9565819]
  • A Stamler, H Wang, R M Weintraub, M D Hariawala, M P Fink, R G Johnson. Low-dose dopexamine's effect on lung and gut function after CPB in a sheep model. The Journal of surgical research. 1998 Feb; 74(2):165-72. doi: 10.1006/jsre.1997.5238. [PMID: 9587356]
  • W Geisser, K Träger, A Hähn, M Georgieff, H Ensinger. Metabolic and calorigenic effects of dopexamine in healthy volunteers. Critical care medicine. 1997 Aug; 25(8):1332-7. doi: 10.1097/00003246-199708000-00020. [PMID: 9267946]
  • E Berendes, T Möllhoff, H Van Aken, C Schmidt, M Erren, M C Deng, M Weyand, H M Loick. Effects of dopexamine on creatinine clearance, systemic inflammation, and splanchnic oxygenation in patients undergoing coronary artery bypass grafting. Anesthesia and analgesia. 1997 May; 84(5):950-7. doi: 10.1097/00000539-199705000-00002. [PMID: 9141914]
  • A Nordin, H Mäkisalo, L Mildh, K Höckerstedt. Dopexamine improves liver oxygenation during crystalloid resuscitation from experimental hemorrhagic shock. Critical care medicine. 1997 Apr; 25(4):663-8. doi: 10.1097/00003246-199704000-00018. [PMID: 9142033]
  • J Pålsson, S E Ricksten, E Houltz, S Lundin. Effects of dopamine, dopexamine and dobutamine on renal excretory function during experimental sepsis in conscious rats. Acta anaesthesiologica Scandinavica. 1997 Mar; 41(3):392-8. doi: 10.1111/j.1399-6576.1997.tb04705.x. [PMID: 9113186]
  • E Sherry, M A Tooley, S N Bolsin, C R Monk, J Willcox. Effect of dopexamine hydrochloride on renal vascular resistance index and haemodynamic responses following coronary artery bypass graft surgery. European journal of anaesthesiology. 1997 Mar; 14(2):184-9. doi: 10.1046/j.1365-2346.1997.00104.x. [PMID: 9088818]
  • S M Jacinto, M S Chintala, M F Lokhandwala, B S Jandhyala. Efficacy and mechanisms of dopexamine in the prevention of ischemia-reperfusion induced organ damage: role of oxygen free radicals. Clinical and experimental hypertension (New York, N.Y. : 1993). 1997 Jan; 19(1-2):181-90. doi: 10.3109/10641969709080814. [PMID: 9028645]
  • W Habre, M Beghetti, C Roduit, E Girardin, M Vallotton, B Friedli, M Berner. Haemodynamic and renal effects of dopexamine after cardiac surgery in children. Anaesthesia and intensive care. 1996 Aug; 24(4):435-9. doi: 10.1177/0310057x9602400404. [PMID: 8862639]
  • D N Gömez-Garre, A López-Farré, N Eleno, J M López-Novoa. Comparative effects of dopexamine and dopamine on glycerol-induced acute renal failure in rats. Renal failure. 1996 Jan; 18(1):59-68. doi: 10.3109/08860229609052774. [PMID: 8820501]
  • S M Jacinto, M F Lokhandwala, B S Jandhyala. Effect of pharmacological interventions in the prevention of lipid peroxidation and respiratory depression induced by oxygen free radicals in anesthetized rats. Free radical biology & medicine. 1996; 21(6):791-9. doi: 10.1016/0891-5849(96)00182-7. [PMID: 8902525]
  • P Kawczynski, A Piotrowski. Circulatory and diuretic effects of dopexamine infusion in low-birth-weight infants with respiratory failure. Intensive care medicine. 1996 Jan; 22(1):65-70. doi: 10.1007/bf01728334. [PMID: 8857441]
  • N D Maynard, D J Bihari, R N Dalton, M N Smithies, R C Mason. Increasing splanchnic blood flow in the critically III. Chest. 1995 Dec; 108(6):1648-54. doi: 10.1378/chest.108.6.1648. [PMID: 7497776]
  • M Welch, C G Newstead, J V Smyth, P D Dodd, M G Walker. Evaluation of dopexamine hydrochloride as a renoprotective agent during aortic surgery. Annals of vascular surgery. 1995 Sep; 9(5):488-92. doi: 10.1007/bf02143865. [PMID: 8541200]
  • S W Martin, K J Broadley. Atypical antagonism of D1-receptor-mediated vasodilator response in the perfused kidney by SCH23390. Pharmacological research. 1995 May; 31(5):289-97. doi: 10.1016/1043-6618(95)80034-4. [PMID: 7479526]
  • S W Martin, K J Broadley. Renal vasodilatation by dopexamine and fenoldopam due to alpha 1-adrenoceptor blockade. British journal of pharmacology. 1995 May; 115(2):349-55. doi: 10.1111/j.1476-5381.1995.tb15884.x. [PMID: 7670737]
  • D A MacGregor, J F Butterworth, C P Zaloga, R C Prielipp, R James, R L Royster. Hemodynamic and renal effects of dopexamine and dobutamine in patients with reduced cardiac output following coronary artery bypass grafting. Chest. 1994 Sep; 106(3):835-41. doi: 10.1378/chest.106.3.835. [PMID: 7915979]
  • S W Martin, K J Broadley. Effects of chronic intravenous infusions of dopexamine and isoprenaline to rats on D1-, beta 1- and beta 2-receptor-mediated responses. British journal of pharmacology. 1994 Jun; 112(2):595-603. doi: 10.1111/j.1476-5381.1994.tb13116.x. [PMID: 7915614]
  • D W Blake, D Way, L Trigg, B P McGrath. Regional blood flow effects of dopexamine versus enalaprilat during propofol anaesthesia in rabbits with experimental chronic heart failure. Cardiovascular research. 1994 May; 28(5):710-4. doi: 10.1093/cvr/28.5.710. [PMID: 8025917]
  • A A Van Lambalgen, A A van Kraats, M F Mulder, T Teerlink, G C van den Bos. High-energy phosphates in heart, liver, kidney, and skeletal muscle of endotoxemic rats. The American journal of physiology. 1994 Apr; 266(4 Pt 2):H1581-7. doi: 10.1152/ajpheart.1994.266.4.h1581. [PMID: 8184937]
  • N V Olsen, J Lund, P F Jensen, K Espersen, I L Kanstrup, I Plum, P P Leyssac. Dopamine, dobutamine, and dopexamine. A comparison of renal effects in unanesthetized human volunteers. Anesthesiology. 1993 Oct; 79(4):685-94. doi: 10.1097/00000542-199310000-00009. [PMID: 8105728]
  • R G van Kesteren, R M Heethaar, G A Charbon, J Heethaar, F A Brouwer. Comparison of effects of dopamine hydrochloride and dopexamine hydrochloride on abdominal and femoral hemodynamics in anesthetized dogs. Circulatory shock. 1993 Jul; 40(3):227-33. doi: NULL. [PMID: 8348685]
  • P Napoleone, C Cavallotti, A Ricci, F Amenta. Dopexamine hydrochloride in the human kidney: localization, receptor binding and effect on 3'-5'-cyclic adenosine monophosphate generation. Nephron. 1993; 65(3):385-91. doi: 10.1159/000187518. [PMID: 7904730]
  • G Perrin, L Papazian, C Martin. [Dopexamine: a new dopaminergic agonist]. Annales francaises d'anesthesie et de reanimation. 1993; 12(3):308-20. doi: 10.1016/s0750-7658(05)80658-6. [PMID: 7902685]
  • A R Girbes, D J Van Veldhuisen, A J Smit. [New dopamine agonists in cardiovascular therapy]. Presse medicale (Paris, France : 1983). 1992 Aug; 21(27):1287-91. doi: NULL. [PMID: 1359528]
  • M M Atallah, M M Saied, T A el-Diasty, P A Gray, G R Park. Renal effect of dopexamine hydrochloride in patients with chronic renal dysfunction. Urological research. 1992; 20(6):419-24. doi: 10.1007/bf00294499. [PMID: 1462481]
  • A S Bass. Presynaptic effects of dopexamine hydrochloride in the canine kidney. Naunyn-Schmiedeberg's archives of pharmacology. 1992 Jan; 345(1):33-6. doi: 10.1007/bf00175466. [PMID: 1347154]
  • T Jaton, M Thonney, J B Gouyon, J P Guignard. Renal effects of dopamine and dopexamine in the newborn anesthetized rabbit. Life sciences. 1992; 50(3):195-202. doi: 10.1016/0024-3205(92)90272-q. [PMID: 1346227]
  • P A Gray, A R Bodenham, G R Park. A comparison of dopexamine and dopamine to prevent renal impairment in patients undergoing orthotopic liver transplantation. Anaesthesia. 1991 Aug; 46(8):638-41. doi: 10.1111/j.1365-2044.1991.tb09711.x. [PMID: 1679611]
  • S J Vyas, S Apparsundaram, A Ricci, F Amenta, M F Lokhandwala. Biochemical, autoradiographic and pharmacological evidence for the involvement of tubular DA-1 receptors in the natriuretic response to dopexamine hydrochloride. Naunyn-Schmiedeberg's archives of pharmacology. 1991 Jan; 343(1):21-30. doi: 10.1007/bf00180672. [PMID: 1674360]
  • T Jaton, M Thonney, J P Guignard. Failure of dopexamine to protect the hypoxemic newborn rabbit kidney. Developmental pharmacology and therapeutics. 1991; 17(3-4):161-6. doi: 10.1159/000457517. [PMID: 1688162]
  • B Du Grès, C Flamens. [Dopexamine: a new catecholamine used in the treatment of low cardiac output after heart surgery]. Annales francaises d'anesthesie et de reanimation. 1991; 10(1):21-7. doi: 10.1016/s0750-7658(05)80267-9. [PMID: 1672583]
  • H Stephan, H Sonntag, H Henning, K Yoshimine. Cardiovascular and renal haemodynamic effects of dopexamine: comparison with dopamine. British journal of anaesthesia. 1990 Sep; 65(3):380-7. doi: 10.1093/bja/65.3.380. [PMID: 1977432]
  • D Wagaine-Twabwe, T J Hendra, C C Smith, J S Yudkin. The effects of dopexamine, a new dopamine analogue, on platelet function in stress. British journal of clinical pharmacology. 1990 Jul; 30(1):87-95. doi: 10.1111/j.1365-2125.1990.tb03747.x. [PMID: 2390435]
  • K Stangl, G Baumann, J Weil, R Gerzer, M Kerscher, H Blömer. [Acute reduction of increased atrial natriuretic peptide level and cyclic guanosine monophosphate in patients with chronic heart failure caused by beta-adrenergic stimulation with dopexamine hydrochloride. Correlation with hemodynamic parameters]. Zeitschrift fur Kardiologie. 1990 Jun; 79(6):417-23. doi: NULL. [PMID: 1974099]
  • A S Bass. Contrasting effects of dopexamine hydrochloride on electrolyte excretion in canine kidney. The Journal of pharmacology and experimental therapeutics. 1990 May; 253(2):798-802. doi: NULL. [PMID: 1971021]
  • G Baumann, S B Felix, S A Filcek. Usefulness of dopexamine hydrochloride versus dobutamine in chronic congestive heart failure and effects on hemodynamics and urine output. The American journal of cardiology. 1990 Mar; 65(11):748-54. doi: 10.1016/0002-9149(90)91382-g. [PMID: 1969223]
  • M F Lokhandwala, S J Vyas, S S Hegde. Renal dopamine and tubular DA-1 receptors in the regulation of sodium excretion. Journal of autonomic pharmacology. 1990; 10 Suppl 1(?):s31-9. doi: 10.1111/j.1474-8673.1990.tb00225.x. [PMID: 1983007]
  • M S Chintala, M F Lokhandwala, B S Jandhyala. Protective effects of dopexamine hydrochloride in renal failure after acute haemorrhage in anaesthetized dogs. Journal of autonomic pharmacology. 1990; 10 Suppl 1(?):s95-102. doi: 10.1111/j.1474-8673.1990.tb00234.x. [PMID: 1965897]
  • A Burns, P A Gray, A R Bodenham, G R Park. Dopexamine: studies in the general intensive care unit and after liver transplantation. Journal of autonomic pharmacology. 1990; 10 Suppl 1(?):s109-14. doi: 10.1111/j.1474-8673.1990.tb00236.x. [PMID: 2098373]
  • F C Colardyn, J F Vandenbogaerde, D P Vogelaers, J H Verbeke. Use of dopexamine hydrochloride in patients with septic shock. Critical care medicine. 1989 Oct; 17(10):999-1003. doi: 10.1097/00003246-198910000-00007. [PMID: 2791586]
  • A S Bass, M B Murphy, J D Kohli, L I Goldberg. Potentiation by dopexamine of the cardiac responses to circulating and neuronally released norepinephrine: a possible mechanism for the therapeutic effects of the drug. Journal of cardiovascular pharmacology. 1989 Apr; 13(4):667-71. doi: 10.1097/00005344-198904000-00022. [PMID: 2471007]
  • B E Jaski, C Peters. Inotropic, vascular and neuroendocrine effects of dopexamine hydrochloride and comparison with dobutamine. The American journal of cardiology. 1988 Aug; 62(5):63C-67C. doi: 10.1016/s0002-9149(88)80070-5. [PMID: 3407597]
  • G P Biro, J R Douglas, W J Keon, G C Taichman. Changes in regional blood flow distribution induced by infusions of dopexamine hydrochloride or dobutamine in anesthetized dogs. The American journal of cardiology. 1988 Aug; 62(5):30C-36C. doi: 10.1016/s0002-9149(88)80064-x. [PMID: 3407595]
  • C V Leier, P F Binkley, J Carpenter, P H Randolph, D V Unverferth. Cardiovascular pharmacology of dopexamine in low output congestive heart failure. The American journal of cardiology. 1988 Jul; 62(1):94-9. doi: 10.1016/0002-9149(88)91371-9. [PMID: 2898209]
  • A R Bodenham, G R Park. Dopexamine hydrochloride, a novel drug with renal vasodilator properties: two case studies. Intensive care medicine. 1988; 14(6):663-5. doi: 10.1007/bf00256775. [PMID: 3183194]
  • J Bayliss, L Thomas, P Poole-Wilson. Acute hemodynamic and neuroendocrine effects of dopexamine, a new vasodilator for the treatment of heart failure: comparison with dobutamine, captopril, and nitrate. Journal of cardiovascular pharmacology. 1987 May; 9(5):551-4. doi: 10.1097/00005344-198705000-00008. [PMID: 2439836]