Erythromycin lactobionate (BioDeep_00000829234)
代谢物信息卡片
Erythromycin lactobionate
化学式: C49H89NO25 (1091.5723384)
中文名称: 乳糖酸阿奇霉素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O.C(C1C(C(C(C(O1)OC(C(CO)O)C(C(C(=O)O)O)O)O)O)O)O
InChI: 3-,4-,5+,6+,7-,8-,9-,10-,12+/m11/s1
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C784 - Protein Synthesis Inhibitor > C261 - Macrolide Antibiotic
C254 - Anti-Infective Agent > C258 - Antibiotic
D005765 - Gastrointestinal Agents
同义名列表
2 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
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PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yang Fan, Wu Shan-Guang, Pan Yu-Fang, Song Feng-Lan, Li Tao. Preparation and characteristics of erythromycin microspheres for lung targeting.
Drug development and industrial pharmacy.
2009 Jun; 35(6):639-45. doi:
10.1080/03639040802512243. [PMID: 19259878] - Narayanan Venkatasubramani, Colin D Rudolph, Manu R Sood. Erythromycin lacks colon prokinetic effect in children with functional gastrointestinal disorders: a retrospective study.
BMC gastroenterology.
2008 Aug; 8(?):38. doi:
10.1186/1471-230x-8-38. [PMID: 18718006] - J Lakritz, W D Wilson, A E Marsh, J E Mihalyi. Pharmacokinetics of erythromycin estolate and erythromycin phosphate after intragastric administration to healthy foals.
American journal of veterinary research.
2000 Aug; 61(8):914-9. doi:
10.2460/ajvr.2000.61.914. [PMID: 10951982] - I E Petrakis, N Vrachassotakis, S J Vassilakis, V Sciacca, G Chalkiadakis. Erythromycin enhances solid-phase gastric emptying in induced-hyperglycemia in patients with truncal vagotomy and pyloroplasty.
Digestive diseases and sciences.
2000 May; 45(5):937-45. doi:
10.1023/a:1005577125356. [PMID: 10795758] - A A Somogyi, F Bochner, D Hetzel, D B Williams. Evaluation of the intestinal absorption of erythromycin in man: absolute bioavailability and comparison with enteric coated erythromycin.
Pharmaceutical research.
1995 Jan; 12(1):149-54. doi:
10.1023/a:1016215510223. [PMID: 7724478] - K B Waites, P J Sims, D T Crouse, M H Geerts, R E Shoup, W B Hamrick, L B Duffy, G H Cassell. Serum concentrations of erythromycin after intravenous infusion in preterm neonates treated for Ureaplasma urealyticum infection.
The Pediatric infectious disease journal.
1994 Apr; 13(4):287-93. doi:
10.1097/00006454-199404000-00008. [PMID: 8036045] - H S Kaufman, S A Ahrendt, H A Pitt, K D Lillemoe. The effect of erythromycin on motility of the duodenum, sphincter of Oddi, and gallbladder in the prairie dog.
Surgery.
1993 Sep; 114(3):543-8. doi:
NULL. [PMID: 8367809] - E M Vasquez, M S Maddux, J Sanchez, R Pollak. Clinically significant hearing loss in renal allograft recipients treated with intravenous erythromycin.
Archives of internal medicine.
1993 Apr; 153(7):879-82. doi:
NULL. [PMID: 8466379] - M Boivin, M Riberdy, M C Raymond, L Trudel, P Poitras. Motilin and the postprandial motility of the antrum.
Canadian journal of physiology and pharmacology.
1992 Nov; 70(11):1491-5. doi:
10.1139/y92-211. [PMID: 1296862] - Y Hirakata, M Kaku, K Tomono, K Tateda, N Furuya, T Matsumoto, R Araki, K Yamaguchi. Efficacy of erythromycin lactobionate for treating Pseudomonas aeruginosa bacteremia in mice.
Antimicrobial agents and chemotherapy.
1992 Jun; 36(6):1198-203. doi:
10.1128/aac.36.6.1198. [PMID: 1416819] - C Agustí, F Ferrán, J Gea, C Picado. Ototoxic reaction to erythromycin.
Archives of internal medicine.
1991 Feb; 151(2):380. doi:
10.1001/archinte.1991.00400020124025. [PMID: 1992966] - J F Camilleri, J C Deharo, D Panagidès, P Broin, T Mésana, D Blin, A Mouly-Bandini, C Dubouloz, A Goudard, J R Montiès. [Jet intravenous injection of erythromycin lactobionate. A possible cause of the occurrence of crisis in torsade de pointe].
Annales de cardiologie et d'angeiologie.
1989 Dec; 38(10):657-9. doi:
NULL. [PMID: 2698118] - R Leuthardt, B Trümpi, R Morger. [Pharmacodynamics of erythromycin lactobionate during tonsillectomy in children].
Schweizerische medizinische Wochenschrift.
1989 Oct; 119(40):1372-4. doi:
NULL. [PMID: 2799345] - A Di Sciacca, F Durante, G Cucchiara, A Ingrassia, G Mira, F Mannone, R M Di Piazza, A Frontini, G Barbagallo Sangiorgi. Effects of intravenous erythromycin lactobionate in respiratory infections.
The Journal of international medical research.
1987 Jul; 15(4):245-50. doi:
10.1177/030006058701500409. [PMID: 3653502] - A Segui, D Milon, M Cormier, G Lepesant. Erythromycin lactobionate: pharmacokinetics and uterine tissue levels.
European journal of drug metabolism and pharmacokinetics.
1987 Jul; 12(3):153-60. doi:
10.1007/bf03189891. [PMID: 3436337] - K M Downey, D M Chaput de Saintonge. Gastrointestinal side effects after intravenous erythromycin lactobionate.
British journal of clinical pharmacology.
1986 Mar; 21(3):295-9. doi:
10.1111/j.1365-2125.1986.tb05193.x. [PMID: 3964530] - R A Walstad, K B Hellum. Penetration of erythromycin in respiratory tract infections.
Acta oto-laryngologica. Supplementum.
1984; 407(?):50-4. doi:
10.3109/00016488409124965. [PMID: 6333775] - G E Marlin, P J Thompson, C R Jenkins, K R Burgess, D A LaFranier. Study of serum levels, venous irritation and gastrointestinal side-effects with intravenous erythromycin lactobionate in patients with bronchopulmonary infection.
Human toxicology.
1983 Oct; 2(4):593-605. doi:
10.1177/096032718300200404. [PMID: 6642516] - D C Warhurst, B L Robinson, W Peters. The blood schizontocidal action of erythromycin against Plasmodium knowlesi infections in Macaca mulatta.
Annals of tropical medicine and parasitology.
1983 Jun; 77(3):231-7. doi:
10.1080/00034983.1983.11811703. [PMID: 6625724] - P D Kroboth, M A McNeil, A Kreeger, J Dominguez, R Rault. Hearing loss and erythromycin pharmacokinetics in a patient receiving hemodialysis.
Archives of internal medicine.
1983 Jun; 143(6):1263-5. doi:
NULL. [PMID: 6860057] - R L Parsons, J A David, K Raymond, S M Stamp. Pharmacokinetics of intravenous erythromycin lactobionate.
The Journal of international medical research.
1980; 8 Suppl 2(?):15-23. doi:
NULL. [PMID: 6968696]