BZ-ALA-OH (BioDeep_00000828613)

   


代谢物信息卡片


N-Benzoyl-L-alanine

化学式: C10H11NO3 (193.0738896)
中文名称: N-苯甲酰-L-丙氨酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C(=O)O)NC(=O)C1=CC=CC=C1
InChI: InChI=1S/C10H11NO3/c1-7(10(13)14)11-9(12)8-5-3-2-4-6-8/h2-7H,1H3,(H,11,12)(H,13,14)/t7-/m0/s1

描述信息

An N-acyl-L-alanine resulting from the formal condensation of L-alanine with the carboxy group of benzoic acid.

同义名列表

2 个代谢物同义名

N-Benzoyl-L-alanine; BZ-ALA-OH



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Pauline Macheboeuf, David Lemaire, Nathalie Teller, Alexandre Dos Santos Martins, André Luxen, Otto Dideberg, Marc Jamin, Andréa Dessen. Trapping of an acyl-enzyme intermediate in a penicillin-binding protein (PBP)-catalyzed reaction. Journal of molecular biology. 2008 Feb; 376(2):405-13. doi: 10.1016/j.jmb.2007.10.066. [PMID: 18155726]
  • Naoyuki Tajima, Hitoshi Ishizuka, Hideo Naganuma. Population pharmacokinetic analysis of panipenem/betamipron in patients with various degrees of renal function. Chemotherapy. 2006; 52(5):245-53. doi: 10.1159/000094745. [PMID: 16864999]
  • Naro Ohashi, Toshihiko Uematsu, Satoru Nagashima, Mitsutaka Kanamaru, Naoyuki Tajima, Akashi Togawa, Akira Hishida. Pharmacokinetics of panipenem/betamipron in patients with end-stage renal disease. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2005 Feb; 11(1):24-31. doi: 10.1007/s10156-004-0359-6. [PMID: 15729484]
  • M Takeda, S Narikawa, M Hosoyamada, S H Cha, T Sekine, H Endou. Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters. European journal of pharmacology. 2001 May; 419(2-3):113-20. doi: 10.1016/s0014-2999(01)00962-1. [PMID: 11426832]
  • Edmund S Ho, Deborah C Lin, Dirk B Mendel, Tomas Cihlar. Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1. Journal of the American Society of Nephrology : JASN. 2000 Mar; 11(3):383-393. doi: 10.1681/asn.v113383. [PMID: 10703662]
  • S H Kim, W B Kim, J W Kwon, M G Lee. Nephroprotective effect of betamipron on a new carbapenem, DA-1131, in rabbits. Biopharmaceutics & drug disposition. 1999 Apr; 20(3):125-9. doi: 10.1002/(sici)1099-081x(199904)20:3<125::aid-bdd163>3.0.co;2-v. [PMID: 10211864]
  • J Tokunaga, M Kobayashi, A Kitagawa, C Nakamura, K Arimori, M Nakano. Protective effects of betamipron on renal toxicity during repeated cisplatin administration in rats and protective mechanism. Renal failure. 1998 Jan; 20(1):27-38. doi: 10.3109/08860229809045087. [PMID: 9509558]
  • J Tokunaga, M Kobayashi, C Nakamura, A Kitagawa, K Arimori, M Nakano. Betamipron reduces cisplatin nephrotoxicity in rodents without modifying its antileukemic activity in mice. Renal failure. 1997 May; 19(3):425-38. doi: 10.3109/08860229709047728. [PMID: 9154659]
  • J Tokunaga, M Kobayashi, A Kitagawa, C Nakamura, K Arimori, M Nakano. Effects of betamipron on cisplatin nephrotoxicity and its pharmacokinetics in rats. Biological & pharmaceutical bulletin. 1997 Apr; 20(4):386-91. doi: 10.1248/bpb.20.386. [PMID: 9145215]
  • J Tokunaga, M Kobayashi, A Kitagawa, C Nakamura, K Arimori, M Nakano. Protective effects of N-benzoyl amino acids on cisplatin nephrotoxicity in rats. Biological & pharmaceutical bulletin. 1996 Nov; 19(11):1451-6. doi: 10.1248/bpb.19.1451. [PMID: 8951163]
  • T Masuda, A Suzuki, M Obana, Y Matsuoka, S Irimajiri. [A case of infective endocarditis with purpura and macroscopic hematuria as initial manifestations]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 1996 Apr; 70(4):366-70. doi: 10.11150/kansenshogakuzasshi1970.70.366. [PMID: 8690952]
  • J Tokunaga, M Kobayashi, C Nakamura, A Kitagawa, K Arimori, M Nakano. Protective effect of N-benzoyl-beta-alanine against cisplatin nephrotoxicity in rats. Renal failure. 1996 Mar; 18(2):225-40. doi: 10.3109/08860229609052792. [PMID: 8723360]
  • Y Hirouchi, H Naganuma, Y Kawahara, R Okada, A Kamiya, K Inui, R Hori. Preventive effect of betamipron on nephrotoxicity and uptake of carbapenems in rabbit renal cortex. Japanese journal of pharmacology. 1994 Sep; 66(1):1-6. doi: 10.1254/jjp.66.1. [PMID: 7861655]
  • J Shimada, Y Kawahara. Overview of a new carbapenem, panipenem/betamipron. Drugs under experimental and clinical research. 1994; 20(6):241-5. doi: NULL. [PMID: 7758396]
  • Y Hirouchi, H Naganuma, Y Kawahara, R Okada, A Kamiya, K Inui, R Hori. Protective effect of N-acyl amino acids (NAAs) on cephaloridine (CER) nephrotoxicity in rabbits. Japanese journal of pharmacology. 1993 Dec; 63(4):487-93. doi: 10.1254/jjp.63.487. [PMID: 7509889]
  • L Wang, T Hasegawa, M Nadai, T Nabeshima. The effects of N-benzoyl-beta-alanine, a new nephroprotective drug, on the distribution and renal excretion of enprofylline in rats. The Journal of pharmacy and pharmacology. 1993 Jul; 45(7):622-6. doi: 10.1111/j.2042-7158.1993.tb05665.x. [PMID: 8105057]
  • S C Jacobson, S Andersson, S G Allenmark, G Guiochon. Estimation of the number of enantioselective sites of bovine serum albumin using frontal chromatography. Chirality. 1993; 5(7):513-5. doi: 10.1002/chir.530050707. [PMID: 8240928]
  • A Kurihara, M Hisaoka, N Mikuni, K Kamoshida. Neurotoxicity of panipenem/betamipron, a new carbapenem, in rabbits: correlation to concentration in central nervous system. Journal of pharmacobio-dynamics. 1992 Jul; 15(7):325-32. doi: 10.1248/bpb1978.15.325. [PMID: 1447679]
  • S C Jacobson, G Guiochon. Contribution of ionically immobilized bovine serum albumin to the retention of enantiomers. Journal of chromatography. 1992 May; 600(1):37-42. doi: 10.1016/0021-9673(92)85434-u. [PMID: 1400844]
  • T Shinka, Y Inoue, T Kuhara, M Matsumoto, I Matsumoto. Benzoylalanine: detection and identification of an alanine conjugate with benzoic acid in hyperammonemic patients treated with sodium benzoate. Clinica chimica acta; international journal of clinical chemistry. 1985 Oct; 151(3):293-300. doi: 10.1016/0009-8981(85)90092-0. [PMID: 4053389]