2-Ethoxyethyl acetate (BioDeep_00000827340)
代谢物信息卡片
Ethylene glycol monoethyl ether acetate
化学式: C6H12O3 (132.0786)
中文名称: 2-乙氧基乙酸乙酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOCCOC(=O)C
InChI: InChI=1S/C6H12O3/c1-3-8-4-5-9-6(2)7/h3-5H2,1-2H3
描述信息
同义名列表
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Wilbur Johnson. Final report on the safety assessment of ethoxyethanol and ethoxyethanol acetate.
International journal of toxicology.
2002; 21 Suppl 1(?):9-62. doi:
10.1080/10915810290096388. [PMID: 12042060] - M L Gargas, T R Tyler, L M Sweeney, R A Corley, K K Weitz, T J Mast, D J Paustenbach, S M Hays. A toxicokinetic study of inhaled ethylene glycol ethyl ether acetate and validation of a physiologically based pharmacokinetic model for rat and human.
Toxicology and applied pharmacology.
2000 May; 165(1):63-73. doi:
10.1006/taap.2000.8927. [PMID: 10814554] - S E Chia, S C Foo, N Y Khoo, J Jeyaratnam. Menstrual patterns of workers exposed to low levels of 2-ethoxyethylacetate (EGEEA).
American journal of industrial medicine.
1997 Feb; 31(2):148-52. doi:
10.1002/(sici)1097-0274(199702)31:2<148::aid-ajim3>3.0.co;2-w. [PMID: 9028430] - B Söhnlein, S Letzel, D Weltle, H W Rüdiger, J Angerer. Occupational chronic exposure to organic solvents. XIV. Examinations concerning the evaluation of a limit value for 2-ethoxyethanol and 2-ethoxyethyl acetate and the genotoxic effects of these glycol ethers.
International archives of occupational and environmental health.
1993; 64(7):479-84. doi:
10.1007/bf00381095. [PMID: 8482587] - L K Lowry, D A Stumpp, C Orbaugh, F Rieders. Applications of biological monitoring in occupational health practice: practical application of urinary 2-ethoxyacetic acid to assess exposure to 2-ethoxyethyl acetate in large format silk-screening operations.
International archives of occupational and environmental health.
1993; 65(1 Suppl):S47-51. doi:
10.1007/bf00381307. [PMID: 8406938] - D Groeseneken, H Veulemans, R Masschelein, E Van Vlem. Ethoxyacetic acid: a metabolite of ethylene glycol monoethyl ether acetate in man.
British journal of industrial medicine.
1987 Jul; 44(7):488-93. doi:
10.1136/oem.44.7.488. [PMID: 3620374] - H Veulemans, D Groeseneken, R Masschelein, E Van Vlem. Field study of the urinary excretion of ethoxyacetic acid during repeated daily exposure to the ethyl ether of ethylene glycol and the ethyl ether of ethylene glycol acetate.
Scandinavian journal of work, environment & health.
1987 Jun; 13(3):239-42. doi:
10.5271/sjweh.2058. [PMID: 3616552] - W T Stott, M J McKenna. Hydrolysis of several glycol ether acetates and acrylate esters by nasal mucosal carboxylesterase in vitro.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1985 Apr; 5(2):399-404. doi:
10.1016/0272-0590(85)90088-0. [PMID: 3988008] - D Guest, M L Hamilton, P J Deisinger, G D DiVincenzo. Pulmonary and percutaneous absorption of 2-propoxyethyl acetate and 2-ethoxyethyl acetate in beagle dogs.
Environmental health perspectives.
1984 Aug; 57(?):177-83. doi:
10.1289/ehp.8457177. [PMID: 6499802]
