Methylprednisolone Sodium Succinate (BioDeep_00000827330)
代谢物信息卡片
6alpha-Methylprednisolone sodium succinate
化学式: C26H33NaO8 (496.20730180000004)
中文名称: 6α-甲基泼尼松龙21-半琥珀酸钠盐
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)COC(=O)CCC(=O)[O-])O.[Na+]
InChI: /q
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents
D000893 - Anti-Inflammatory Agents
D000970 - Antineoplastic Agents
D020011 - Protective Agents
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:6890
- KEGGdrug: D95085
- KEGGdrug: D00751
- PubChem: 23680530
- ChEMBL: CHEMBL1201081
- MeSH: Methylprednisolone Hemisuccinate
- CAS: 2375-03-3
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kai Chen, Bo Li, Hao Xu, Ji Wu, Jianhua Li, Wuquan Sun, Min Fang, Wei Wang, Shige Wang, Xiao Zhai. Zeolitic imidazole framework-8 loaded gelatin methacryloyl microneedles: A transdural and controlled-release drug delivery system attenuates neuroinflammation after spinal cord injury.
International journal of biological macromolecules.
2024 Jan; 256(Pt 1):128388. doi:
10.1016/j.ijbiomac.2023.128388. [PMID: 38016601] - Nader Hejrati, Bizhan Aarabi, Chris J Neal, Beatrice Ugiliweneza, Shekar N Kurpad, Christopher I Shaffrey, James D Guest, Elizabeth G Toups, James S Harrop, Michael G Fehlings. Trends in the Use of Corticosteroids in the Management of Acute Spinal Cord Injury in North American Clinical Trials Network Sites.
Journal of neurotrauma.
2023 09; 40(17-18):1938-1947. doi:
10.1089/neu.2022.0409. [PMID: 36597351] - Jodi L Nelson, Gregory M Blume, Saurabh K Bansal, Jacqueline R Kaufman, Florence R Woods, Xiaojun Zhang, Jorge C Kattah. Postinfectious SARS-CoV-2 Opsoclonus-Myoclonus-Ataxia Syndrome.
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society.
2022 06; 42(2):251-255. doi:
10.1097/wno.0000000000001498. [PMID: 34974489] - Vijairam Selvaraj, Abdelmoniem Moustafa, Kwame Dapaah-Afriyie, Mark P Birkenbach. COVID-19-induced granulomatosis with polyangiitis.
BMJ case reports.
2021 Mar; 14(3):. doi:
10.1136/bcr-2021-242142. [PMID: 33737283] - Foteini Stefania Koumpa, Cillian T Forde, Joseph G Manjaly. Sudden irreversible hearing loss post COVID-19.
BMJ case reports.
2020 Oct; 13(11):. doi:
10.1136/bcr-2020-238419. [PMID: 33051251] - Daniel O Griffin, Alexandra Jensen, Mushmoom Khan, Jessica Chin, Kelly Chin, Jennifer Saad, Ryan Parnell, Christopher Awwad, Darshan Patel. Pulmonary Embolism and Increased Levels of d-Dimer in Patients with Coronavirus Disease.
Emerging infectious diseases.
2020 Aug; 26(8):1941-1943. doi:
10.3201/eid2608.201477. [PMID: 32348233] - Daping Cui, Dewei Zhao, Shibo Huang. Structural characterization of a safflower polysaccharide and its promotion effect on steroid-induced osteonecrosis in vivo.
Carbohydrate polymers.
2020 Apr; 233(?):115856. doi:
10.1016/j.carbpol.2020.115856. [PMID: 32059907] - Lokesh Shah, David K Hooper, Daryl Okamura, Dean Wallace, Divya Moodalbail, Caroline Gluck, Ania Koziell, Joshua J Zaritsky. LDL-apheresis-induced remission of focal segmental glomerulosclerosis recurrence in pediatric renal transplant recipients.
Pediatric nephrology (Berlin, Germany).
2019 11; 34(11):2343-2350. doi:
10.1007/s00467-019-04296-6. [PMID: 31250206] - Xiumei Gai, Zhujun Jiang, Mengqi Liu, Qi Li, Shu Wang, Ting Li, Weisan Pan, Xinggang Yang. Therapeutic Effect of a Novel Nano-Drug Delivery System on Membranous Glomerulonephritis Rat Model Induced by Cationic Bovine Serum.
AAPS PharmSciTech.
2018 Jul; 19(5):2195-2202. doi:
10.1208/s12249-018-1034-z. [PMID: 29725902] - Marat I Kamalov, Trinh Đặng, Natalia V Petrova, Alexander V Laikov, Duong Luong, Rezeda A Akhmadishina, Andrei N Lukashkin, Timur I Abdullin. Self-assembled nanoformulation of methylprednisolone succinate with carboxylated block copolymer for local glucocorticoid therapy.
Colloids and surfaces. B, Biointerfaces.
2018 Apr; 164(?):78-88. doi:
10.1016/j.colsurfb.2018.01.014. [PMID: 29413623] - Megan Donovan, Andrew DePiero. Acute transverse myelitis in a pediatric patient.
The American journal of emergency medicine.
2017 07; 35(7):1034.e3-1034.e4. doi:
10.1016/j.ajem.2017.02.014. [PMID: 28215959] - L Vatin, J M Foletti, C Collet, A Varoquaux, C Chossegros. A case of bilateral megaducts: Diagnostic and treatment methods.
Journal of stomatology, oral and maxillofacial surgery.
2017 Apr; 118(2):125-128. doi:
10.1016/j.jormas.2017.01.004. [PMID: 28345516] - Amit Sharma, Anne King, Dhiren Kumar, Martha Behnke, Felecia McDougan, Pamela M Kimball. Perioperative Desensitization Improves Outcomes Among Crossmatch Positive Recipients of Deceased Donor Renal Transplants.
Progress in transplantation (Aliso Viejo, Calif.).
2016 Jun; 26(2):157-61. doi:
10.1177/1526924816640678. [PMID: 27207404] - C Donzé, A Dinh, O Heinzlef, P Hautecoeur. [To treat or not to treat asymptomatic bacteriuria before methylprednisolone perfusion].
Revue neurologique.
2015 Sep; 171(8-9):669-73. doi:
10.1016/j.neurol.2015.04.013. [PMID: 26318899] - Min C Yoo, Jason M Vanatta, Kian A Modanlou, Luis Campos, Nosratollah Nezakatgoo, Satheesh Nair, James D Eason. Steroid-free Liver Transplantation Using Rabbit Antithymocyte Globulin Induction in 500 Consecutive Patients.
Transplantation.
2015 Jun; 99(6):1231-5. doi:
10.1097/tp.0000000000000477. [PMID: 25539464] - Katherine Twombley, Lonnie Thach, Annelise Ribeiro, Catherine Joseph, Mouin Seikaly. Acute antibody-mediated rejection in pediatric kidney transplants: a single center experience.
Pediatric transplantation.
2013 Nov; 17(7):E149-55. doi:
10.1111/petr.12129. [PMID: 23901848] - Christos Krogias, Robert Hoepner, Andre Müller, Christiane Schneider-Gold, Alexandra Schröder, Ralf Gold. Successful treatment of anti-Caspr2 syndrome by interleukin 6 receptor blockade through tocilizumab.
JAMA neurology.
2013 Aug; 70(8):1056-9. doi:
10.1001/jamaneurol.2013.143. [PMID: 23778873] - M Sayın, P Temiz, A Var, C Temiz. The dose-dependent neuroprotective effect of alpha-lipoic acid in experimental spinal cord injury.
Neurologia i neurochirurgia polska.
2013 Jul; 47(4):345-51. doi:
10.5114/ninp.2013.36207. [PMID: 23986424] - Hoda Derakhshanian, Mahmoud Djalali, Abolghassem Djazayery, Keramat Nourijelyani, Sajad Ghadbeigi, Hamideh Pishva, Ahmad Saedisomeolia, Arash Bahremand, Ahmad Reza Dehpour. Quercetin prevents experimental glucocorticoid-induced osteoporosis: a comparative study with alendronate.
Canadian journal of physiology and pharmacology.
2013 May; 91(5):380-5. doi:
10.1139/cjpp-2012-0190. [PMID: 23656499] - Danielle Morello Park, Teresa Lúcia Lamano Carvalho, Janete Aparecida Anselmo Franci, Wilma Terezinha Anselmo-Lima. Influence of treatment with intranasal corticosteroids on the nasal mucosa, weight, and corticosteroid concentration in rats.
American journal of rhinology & allergy.
2012 Jan; 26(1):e46-9. doi:
10.2500/ajra.2012.26.3702. [PMID: 22182666] - Ahmet Metin Sanli, Erhan Turkoglu, Gokhan Serbes, Mustafa Fevzi Sargon, Omer Besalti, Kamer Kilinc, Alper Irak, Zeki Sekerci. Effect of curcumin on lipid peroxidation, early ultrastructural findings and neurological recovery after experimental spinal cord contusion injury in rats.
Turkish neurosurgery.
2012; 22(2):189-95. doi:
10.5137/1019-5149.jtn.5193-11.1. [PMID: 22437293] - Ann Ming Yeh, Amirkaveh Mojtahed, Dorsey Bass. Acute liver failure and aplastic anemia in an 11-year-old girl.
Digestive diseases and sciences.
2011 Aug; 56(8):2237-40. doi:
10.1007/s10620-011-1678-y. [PMID: 21442323] - A Metin Sanli, Gökhan Serbes, Murat Calişkan, Erkan Kaptanoğlu, Mustafa F Sargon, Kamer Kilinç, Omer Beşalti, Zeki Sekerci. Effect of granulocyte-colony stimulating factor on spinal cord tissue after experimental contusion injury.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia.
2010 Dec; 17(12):1548-52. doi:
10.1016/j.jocn.2010.03.043. [PMID: 20801040] - Taigo Kato, Koji Yazawa, Keigo Madono, Jun Saito, Masahiro Hosomi, Kiichiro Itoh. Acute graft-versus-host-disease in kidney transplantation: case report and review of literature.
Transplantation proceedings.
2009 11; 41(9):3949-52. doi:
10.1016/j.transproceed.2009.05.030. [PMID: 19917421] - Kenar D Jhaveri, Abby Scheuer, Jules Cohen, Bruce Gordon. Treatment of refractory thrombotic thrombocytopenic purpura using multimodality therapy including splenectomy and cyclosporine.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.
2009 Aug; 41(1):19-22. doi:
10.1016/j.transci.2009.05.007. [PMID: 19520610] - Tina Abdelnour, Steve Rieke. Relationship of hormonal resuscitation therapy and central venous pressure on increasing organs for transplant.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
2009 May; 28(5):480-5. doi:
10.1016/j.healun.2009.01.018. [PMID: 19416777] - A Gelincik, H Yazici, T Emre, F Yakar, S Buyukozturk. An alternative approach to a renal transplant patient who experienced an immediate type systemic reaction due to methylprednisolone sodium succinate.
Journal of investigational allergology & clinical immunology.
2009; 19(2):162-3. doi:
NULL. [PMID: 19476024] - Y W Nah, C W Nam, J H Suh, H J Cha, G Y Kim, S J Park, Y Oh, H R Cho. Isolated acute cellular rejection of the liver after simultaneous liver and kidney transplantation: a case report.
Transplantation proceedings.
2008 Oct; 40(8):2832-4. doi:
10.1016/j.transproceed.2008.08.021. [PMID: 18929875] - Helen C Atkinson, Susan A Wood, Emma S Castrique, Yvonne M Kershaw, Crispin C R Wiles, Stafford L Lightman. Corticosteroids mediate fast feedback of the rat hypothalamic-pituitary-adrenal axis via the mineralocorticoid receptor.
American journal of physiology. Endocrinology and metabolism.
2008 Jun; 294(6):E1011-22. doi:
10.1152/ajpendo.00721.2007. [PMID: 18349112] - J Proença Pina, K Ssi-Yan-Kai, I de Monchy, B Charpentier, H Offret, M Labetoulle. [Purtscher-like retinopathy: case report and review of the literature].
Journal francais d'ophtalmologie.
2008 Jun; 31(6 Pt 1):609-13. doi:
10.1016/s0181-5512(08)75463-9. [PMID: 18772813] - Anasuya Hazra, Nancy A Pyszczynski, Debra C DuBois, Richard R Almon, William J Jusko. Modeling of corticosteroid effects on hepatic low-density lipoprotein receptors and plasma lipid dynamics in rats.
Pharmaceutical research.
2008 Apr; 25(4):769-80. doi:
10.1007/s11095-007-9371-8. [PMID: 17674160] - Nobito Higuchi, Masaki Kato, Kazuhiro Kotoh, Motoyuki Kohjima, Shinichi Aishima, Makoto Nakamuta, Yoshinori Fukui, Ryoichi Takayanagi, Munechika Enjoji. Methylprednisolone injection via the portal vein suppresses inflammation in acute liver failure induced in rats by lipopolysaccharide and d-galactosamine.
Liver international : official journal of the International Association for the Study of the Liver.
2007 Dec; 27(10):1342-8. doi:
10.1111/j.1478-3231.2007.01590.x. [PMID: 17900243] - Christophe Gellis, Valérie Sautou-Miranda, Nathalie Bleyzac, Jean-François Jarrige, Régine Minet-Quinard, Jean Chopineau. Continuous infusion of methylprednisolone via paediatric parenteral nutrition: a pharmacokinetic animal study.
Clinical nutrition (Edinburgh, Scotland).
2007 Aug; 26(4):491-7. doi:
10.1016/j.clnu.2007.02.005. [PMID: 17442463] - Jenny K McCormick, Eric S Nadel, David F M Brown. Rash and neurological symptoms.
The Journal of emergency medicine.
2007 Apr; 32(3):299-303. doi:
10.1016/j.jemermed.2006.12.036. [PMID: 17394996] - Avi Schroeder, Yuval Avnir, Sarah Weisman, Yousef Najajreh, Alberto Gabizon, Yeshayahu Talmon, Joseph Kost, Yechezkel Barenholz. Controlling liposomal drug release with low frequency ultrasound: mechanism and feasibility.
Langmuir : the ACS journal of surfaces and colloids.
2007 Mar; 23(7):4019-25. doi:
10.1021/la0631668. [PMID: 17319706] - Sven C Schmidt, Susanne Hamann, Jan M Langrehr, Conny Höflich, Jens Mittler, Dictmar Jacob, Peter Neuhaus. Preoperative high-dose steroid administration attenuates the surgical stress response following liver resection: results of a prospective randomized study.
Journal of hepato-biliary-pancreatic surgery.
2007; 14(5):484-92. doi:
10.1007/s00534-006-1200-7. [PMID: 17909718] - Jorge E Hachmeister, Lokanatha Valluru, Feng Bao, Danxia Liu. Mn (III) tetrakis (4-benzoic acid) porphyrin administered into the intrathecal space reduces oxidative damage and neuron death after spinal cord injury: a comparison with methylprednisolone.
Journal of neurotrauma.
2006 Dec; 23(12):1766-78. doi:
10.1089/neu.2006.23.1766. [PMID: 17184187] - Erkan Yildirim, Kanat Ozisik, Pinar Ozisik, Mustafa Emir, Engin Yildirim, Müge Misirlioglu, Serdar Tuncer, Kamer Kilinc. Apoptosis-related gene bcl-2 in lung tissue after experimental traumatic brain injury in rats.
Heart, lung & circulation.
2006 Apr; 15(2):124-9. doi:
10.1016/j.hlc.2005.10.001. [PMID: 16490400] - Mustafa Emir, Kanat Ozisik, Kerim Cagli, Pinar Ozisik, Serdar Tuncer, Vedat Bakuy, Erkan Yildirim, Kamer Kilinc, Kamil Gol. Beneficial effect of methylprednisolone on cardiac myocytes in a rat model of severe brain injury.
The Tohoku journal of experimental medicine.
2005 Oct; 207(2):119-24. doi:
10.1620/tjem.207.119. [PMID: 16141680] - Tomomi Furihata, Masakiyo Hosokawa, Ayako Fujii, Maher Derbel, Tetsuo Satoh, Kan Chiba. Dexamethasone-induced methylprednisolone hemisuccinate hydrolase: its identification as a member of the rat carboxylesterase 2 family and its unique existence in plasma.
Biochemical pharmacology.
2005 Apr; 69(8):1287-97. doi:
10.1016/j.bcp.2005.01.017. [PMID: 15794950] - Naricha Chirakalwasan, Mohammed M Dallal. Pulmonary sarcoidosis presenting with acute respiratory failure.
Southern medical journal.
2005 Mar; 98(3):382-4. doi:
10.1097/01.smj.0000154317.31912.e1. [PMID: 15813166] - J Barth, J Winkler, R Schumann, N V Nagaraja, R Madabushi, S Balbach, H Derendorf, H Möllmann, G Möllenhoff. Population pharmacokinetics of methylprednisolone in accident victims with spinal cord injury.
International journal of clinical pharmacology and therapeutics.
2004 Sep; 42(9):504-11. doi:
10.5414/cpp42504. [PMID: 15487809] - Christophe Gellis, Valérie Sautou-Miranda, Jean-François Jarrige, Anne Grand-Boyer, Nathalie Bleyzac, Jean Chopineau. Methylprednisolone sodium succinate in pediatric parenteral nutrition: influence of vehicle injection.
Clinical nutrition (Edinburgh, Scotland).
2004 Aug; 23(4):515-25. doi:
10.1016/j.clnu.2003.09.009. [PMID: 15297087] - Kirk H Waibel, Rohit K Katial. Serum sickness-like reaction and bupropion.
Journal of the American Academy of Child and Adolescent Psychiatry.
2004 May; 43(5):509. doi:
10.1097/00004583-200405000-00001. [PMID: 15100554] - James A Tumlin, R A Hennigar. Clinical presentation, natural history, and treatment of crescentic proliferative IgA nephropathy.
Seminars in nephrology.
2004 May; 24(3):256-68. doi:
10.1016/j.semnephrol.2004.01.006. [PMID: 15156530] - Hiroki Konishi, Masaki Sumi, Nobuhito Shibata, Kanji Takada, Tokuzo Minouchi, Akira Yamaji. Influence of intravenous methylprednisolone pulse treatment on the disposition of ciclosporin and hepatic CYP3A activity in rats.
The Journal of pharmacy and pharmacology.
2004 Apr; 56(4):477-83. doi:
10.1211/0022357023114. [PMID: 15099443] - Darko Anić, Hrvoje Gasparović, Visnja Ivancan, Drago Batinić. Effects of corticosteroids on inflammatory response following cardiopulmonary bypass.
Croatian medical journal.
2004 Apr; 45(2):158-61. doi:
NULL. [PMID: 15103751] - Ryoichi Saito, Seiji Moroi, Hiroshi Okuno, Osamu Ogawa. Anaphylaxis following administration of intravenous methylprednisolone sodium succinate in a renal transplant recipient.
International journal of urology : official journal of the Japanese Urological Association.
2004 Mar; 11(3):171-4. doi:
10.1111/j.1442-2042.2003.00769.x. [PMID: 15009366] - Takashi Tokashiki, Teruto Hashiguchi, Kimiyoshi Arimura, Nobutaka Eiraku, Ikuro Maruyama, Mitsuhiro Osame. Predictive value of serial platelet count and VEGF determination for the management of DIC in the Crow-Fukase (POEMS) syndrome.
Internal medicine (Tokyo, Japan).
2003 Dec; 42(12):1240-3. doi:
10.2169/internalmedicine.42.1240. [PMID: 14714967] - P D Acott, J F S Crocker, J A Wong. Decreased bone mineral density in the pediatric renal transplant population.
Pediatric transplantation.
2003 Oct; 7(5):358-63. doi:
10.1034/j.1399-3046.2003.00060.x. [PMID: 14738295] - R Press, M Pashenkov, J P Jin, H Link. Aberrated levels of cerebrospinal fluid chemokines in Guillain-Barré syndrome and chronic inflammatory demyelinating polyradiculoneuropathy.
Journal of clinical immunology.
2003 Jul; 23(4):259-67. doi:
10.1023/a:1024532715775. [PMID: 12959218] - James A Tumlin, Verachai Lohavichan, Randy Hennigar. Crescentic, proliferative IgA nephropathy: clinical and histological response to methylprednisolone and intravenous cyclophosphamide.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2003 Jul; 18(7):1321-9. doi:
10.1093/ndt/gfg081. [PMID: 12808169] - Tatjana Burgdorff, Lennart Venemalm, Thomas Vogt, Michael Landthaler, Wilhelm Stolz. IgE-mediated anaphylactic reaction induced by succinate ester of methylprednisolone.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
2002 Oct; 89(4):425-8. doi:
10.1016/s1081-1206(10)62046-7. [PMID: 12392389] - X Zhang, R Mehvar. Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: plasma and tissue disposition.
Journal of pharmaceutical sciences.
2001 Dec; 90(12):2078-87. doi:
10.1002/jps.1158. [PMID: 11745766] - D Liu, L Li, L Augustus. Prostaglandin release by spinal cord injury mediates production of hydroxyl radical, malondialdehyde and cell death: a site of the neuroprotective action of methylprednisolone.
Journal of neurochemistry.
2001 May; 77(4):1036-47. doi:
10.1046/j.1471-4159.2001.00306.x. [PMID: 11359869] - Y Yamashita , M Shimada, T Hamatsu, T Rikimaru, S Tanaka, K Shirabe, K Sugimachi. Effects of preoperative steroid administration on surgical stress in hepatic resection: prospective randomized trial.
Archives of surgery (Chicago, Ill. : 1960).
2001 Mar; 136(3):328-33. doi:
10.1001/archsurg.136.3.328. [PMID: 11231856] - G Chaine, M Haouat, C Menard-Molcard, C Favard, C Vignal-Clermont, F Campinchi-Tardy, P Massin, A Gaudric, I Badelon, L Nicolon, P Sabatier, L Guillevin. [Central serous chorioretinopathy and systemic steroid therapy].
Journal francais d'ophtalmologie.
2001 Feb; 24(2):139-46. doi:
NULL. [PMID: 11240484] - S Chowdhury, R K Kode, K Ranganna, A M Damask, A Lam, B Fyfe, S Stabler, A M Kumar, M B Tomeny, M S Kumar, O Pankewycz. Induction strategy using basiliximab combined with mycophenolate MMF and immediate low-dose cyclosporin is steroid sparing and more effective than OKT3.
Transplantation proceedings.
2001 Feb; 33(1-2):1057-8. doi:
10.1016/s0041-1345(00)02414-3. [PMID: 11267189] - F F Behar-Cohen, S Gauthier, A El Aouni, P Chapon, J M Parel, G Renard, D Chauvaud. Methylprednisolone concentrations in the vitreous and the serum after pulse therapy.
Retina (Philadelphia, Pa.).
2001; 21(1):48-53. doi:
10.1097/00006982-200102000-00008. [PMID: 11217929] - R Mehvar, D A Hoganson. Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: immunosuppressive effects after in vivo administration to rats.
Pharmaceutical research.
2000 Nov; 17(11):1402-7. doi:
10.1023/a:1007555107691. [PMID: 11205734] - R Mehvar. High-performance size-exclusion chromatographic analysis of dextran-methylprednisolone hemisuccinate in rat plasma.
Journal of chromatography. B, Biomedical sciences and applications.
2000 Jul; 744(2):293-8. doi:
10.1016/s0378-4347(00)00256-5. [PMID: 10993517] - R Mehvar, R O Dann, D A Hoganson. Simultaneous analysis of methylprednisolone, methylprednisolone succinate, and endogenous corticosterone in rat plasma.
Journal of pharmaceutical and biomedical analysis.
2000 Jul; 22(6):1015-22. doi:
10.1016/s0731-7085(00)00253-3. [PMID: 10857570] - M Hänel, N Kröger, M M Hoffknecht, S O Peters, B Metzner, F Fiedler, D Braumann, J C Schubert, H J Illiger, A Hänel, W H Krüger, W Zeller, H J Weh, D K Hossfeld, A R Zander. ASHAP--an effective salvage therapy for recurrent and refractory malignant lymphomas.
Annals of hematology.
2000 Jun; 79(6):304-11. doi:
10.1007/s002779900150. [PMID: 10901609] - I Elovaara, M Ukkonen, M Leppäkynnäs, T Lehtimäki, M Luomala, J Peltola, P Dastidar. Adhesion molecules in multiple sclerosis: relation to subtypes of disease and methylprednisolone therapy.
Archives of neurology.
2000 Apr; 57(4):546-51. doi:
10.1001/archneur.57.4.546. [PMID: 10768630] - K Shimanuki, M Satake. Evaluation of perioperative administration of methylprednisolone sodium succinate and urinary trypsin inhibitor for prevention of surgical stress.
Fukushima journal of medical science.
1999 Dec; 45(2):93-107. doi:
NULL. [PMID: 11039606] - T B Vree, L Maljers, N Van den Borg, N M Nibbering, C P Verwey-van Wissen, A J Lagerwerf, R A Maes, P J Jongen. High-performance liquid-chromatographic-atmospheric-pressure chemical-ionization ion-trap mass-spectrometric identification of isomeric C6-hydroxy and C20-hydroxy metabolites of methylprednisolone in the urine of patients receiving high-dose pulse therapy.
The Journal of pharmacy and pharmacology.
1999 Oct; 51(10):1155-66. doi:
10.1211/0022357991776697. [PMID: 10579687] - E Kaptanoglu, H H Caner, H S Sürücü, F Akbiyik. Effect of mexiletine on lipid peroxidation and early ultrastructural findings in experimental spinal cord injury.
Journal of neurosurgery.
1999 Oct; 91(2 Suppl):200-4. doi:
10.3171/spi.1999.91.2.0200. [PMID: 10505505] - C R Rohrer, R C Hill, A Fischer, L E Fox, M Schaer, P E Ginn, V A Preast, C F Burrows. Efficacy of misoprostol in prevention of gastric hemorrhage in dogs treated with high doses of methylprednisolone sodium succinate.
American journal of veterinary research.
1999 Aug; 60(8):982-5. doi:
NULL. [PMID: 10451209] - J Jakab, P Borka, I Hoffer, F Perner, E Gyódi, K Rajczy, G Petrányi, J Szabó. Possible role of post renal transplant graft-versus-host antibodies in preventing acute graft rejection.
Transplantation proceedings.
1998 Dec; 30(8):3981-3. doi:
10.1016/s0041-1345(98)01312-8. [PMID: 9865269] - G S Markowitz, A Tartini, V D D'Agati. Acute interstitial nephritis following treatment with anorectic agents phentermine and phendimetrazine.
Clinical nephrology.
1998 Oct; 50(4):252-4. doi:
. [PMID: 9799071] - D Van Buren, J Payne, S Geevarghese, R MacDonell, W Chapman, J K Wright, J H Helderman, R Richie, C W Pinson. Impact of Sandimmune, Neoral, and Prograf on rejection incidence and renal function in primary liver transplant recipients.
Transplantation proceedings.
1998 Aug; 30(5):1830-2. doi:
10.1016/s0041-1345(98)00448-5. [PMID: 9723299] - G W Burke, G Ciancio, R Alejandro, D Roth, C Ricordi, A Tzakis, J Miller. Use of tacrolimus and mycophenolate mofetil for pancreas-kidney transplantation with or without OKT3 induction.
Transplantation proceedings.
1998 Jun; 30(4):1544-5. doi:
10.1016/s0041-1345(98)00350-9. [PMID: 9636627] - H P Grewal, J R Thistlethwaite, G E Loss, D S Bruce, C T Siegel, D C Cronin, K A Newell, J M Millis, E S Woodle. Corticosteroid cessation 1 week following renal transplantation using tacrolimus/mycophenolate mofetil based immunosuppression.
Transplantation proceedings.
1998 Jun; 30(4):1378-9. doi:
10.1016/s0041-1345(98)00281-4. [PMID: 9636558] - S M Hanson, D R Bostwick, D C Twedt, M O Smith. Clinical evaluation of cimetidine, sucralfate, and misoprostol for prevention of gastrointestinal tract bleeding in dogs undergoing spinal surgery.
American journal of veterinary research.
1997 Nov; 58(11):1320-3. doi:
NULL. [PMID: 9361899] - R S Larson, D C Brown, L A Sklar. Retinoic acid induces aggregation of the acute promyelocytic leukemia cell line NB-4 by utilization of LFA-1 and ICAM-2.
Blood.
1997 Oct; 90(7):2747-56. doi:
NULL. [PMID: 9326242] - M E Falagas, D R Snydman, R Ruthazer, J Griffith, B G Werner, R Freeman, R Rohrer. Cytomegalovirus immune globulin (CMVIG) prophylaxis is associated with increased survival after orthotopic liver transplantation. The Boston Center for Liver Transplantation CMVIG Study Group.
Clinical transplantation.
1997 Oct; 11(5 Pt 1):432-7. doi:
NULL. [PMID: 9361936] - E S Woodle, K A Newell, M Haas, S Bartosh, M A Josephson, J M Millis, D S Bruce, J B Piper, A J Aronson, J R Thistlethwaite. Reversal of accelerated renal allograft rejection with FK 506.
Clinical transplantation.
1997 Aug; 11(4):251-4. doi:
NULL. [PMID: 9267710] - P T Daley-Yates, A J Gregory, C D Brooks. Pharmacokinetic and pharmacodynamic assessment of bioavailability for two prodrugs of methylprednisolone.
British journal of clinical pharmacology.
1997 Jun; 43(6):593-601. doi:
10.1046/j.1365-2125.1997.00598.x. [PMID: 9205819] - S Schulze, J Andersen, H Overgaard, P Nørgard, H J Nielsen, A Aasen, F Gottrup, H Kehlet. Effect of prednisolone on the systemic response and wound healing after colonic surgery.
Archives of surgery (Chicago, Ill. : 1960).
1997 Feb; 132(2):129-35. doi:
10.1001/archsurg.1997.01430260027005. [PMID: 9041914] - M S Abouljoud, K A Brown, E May, P Baliad, F S Escobar, M F Mozes. Cost-effective management of acute rejection in liver transplant recipients: a managed care perspective.
Transplantation proceedings.
1997 Feb; 29(1-2):1557-9. doi:
10.1016/s0041-1345(96)00673-2. [PMID: 9123423] - N Scott-Douglas, D Zimmerman, J Klassen. Treatment of acute renal transplant rejection with FK 506 in patients on cyclosporine after failure of standard antirejection therapy.
Transplantation proceedings.
1996 Dec; 28(6):3165. doi:
NULL. [PMID: 8962226] - J S Hanrahan, H Ibrahim, D Tolman, D Kirchberg, D Salter, A Guerraty, P K Mohanty. Relative clinical impact of cyclosporine vs steroid induction therapy on renal function and allograft rejection in heart transplant recipients.
Transplantation proceedings.
1996 Aug; 28(4):2107-8. doi:
NULL. [PMID: 8769168] - G A Levy. Case study: conversion of a liver transplant patient from cyclosporine Sandimmune to Neoral.
Transplantation proceedings.
1996 Aug; 28(4):2252-3. doi:
NULL. [PMID: 8769216] - R J Fingerote, M Abecassis, M J Phillips, Y S Rao, E H Cole, J Leibowitz, G A Levy. Loss of resistance to murine hepatitis virus strain 3 infection after treatment with corticosteroids is associated with induction of macrophage procoagulant activity.
Journal of virology.
1996 Jul; 70(7):4275-82. doi:
10.1128/jvi.70.7.4275-4282.1996. [PMID: 8676449] - T Farquhar, R J Todhunter, S L Fubini, N Burton-Wurster, G Lust. Effect of methylprednisolone and mechanical loading on canine articular cartilage in explant culture.
Osteoarthritis and cartilage.
1996 Mar; 4(1):55-62. doi:
10.1016/s1063-4584(96)80007-0. [PMID: 8731396] - D J Goldstein, M C Oz, C R Smith, J P Friedlander, C M De Rosa, L B Mongero, E Delphin. Safety of repeat aprotinin administration for LVAD recipients undergoing cardiac transplantation.
The Annals of thoracic surgery.
1996 Feb; 61(2):692-5. doi:
10.1016/0003-4975(95)01041-6. [PMID: 8572789] - W R Bachman, J K Brennan. Refractory thrombotic thrombocytopenic purpura treated with cyclosporine.
American journal of hematology.
1996 Jan; 51(1):93-4. doi:
10.1002/(sici)1096-8652(199601)51:1<93::aid-ajh16>3.0.co;2-c. [PMID: 8571946] - H Røshol, K K Skrede, C E AErø, P Wiik. Dexamethasone and methylprednisolone affect rat peritoneal phagocyte chemiluminescence after administration in vivo.
European journal of pharmacology.
1995 Nov; 286(1):9-17. doi:
10.1016/0014-2999(95)00430-s. [PMID: 8566155] - G U Meduri, S Headley, E Tolley, M Shelby, F Stentz, A Postlethwaite. Plasma and BAL cytokine response to corticosteroid rescue treatment in late ARDS.
Chest.
1995 Nov; 108(5):1315-25. doi:
10.1378/chest.108.5.1315. [PMID: 7587435] - J E Cortes, M Talpaz, F Cabanillas, J F Seymour, R Kurzrock. Serum levels of interleukin-10 in patients with diffuse large cell lymphoma: lack of correlation with prognosis.
Blood.
1995 May; 85(9):2516-20. doi:
10.1182/blood.v85.9.2516.bloodjournal8592516. [PMID: 7537119] - P I Lobo, C E Spencer, W C Stevenson, T L Pruett. Evidence demonstrating poor kidney graft survival when acute rejections are associated with IgG donor-specific lymphocytotoxin.
Transplantation.
1995 Feb; 59(3):357-60. doi:
10.1097/00007890-199502150-00009. [PMID: 7871565] - G J Lawson, J Chakraborty, J M Tredger, E M Baylis. Methylprednisolone-hemisuccinate and its metabolites in serum, urine and bile from two patients with acute graft rejection.
British journal of clinical pharmacology.
1995 Feb; 39(2):176-8. doi:
10.1111/j.1365-2125.1995.tb04426.x. [PMID: 7742157] - E S Woodle, G A Perdrizet, S K So, H M White, J W Marsh. FK 506 rescue therapy for hepatic allograft rejection: experience with an aggressive approach.
Clinical transplantation.
1995 Feb; 9(1):45-52. doi:
NULL. [PMID: 7537988] - J J Ferry, A A Della-Coletta, D J Weber, J T VanderLugt. Pilot study of the pharmacokinetics of methylprednisolone after single and multiple intravenous doses of methylprednisolone sodium succinate and methylprednisolone suleptanate to healthy volunteers.
Journal of clinical pharmacology.
1994 Nov; 34(11):1109-15. doi:
10.1002/j.1552-4604.1994.tb01988.x. [PMID: 7876403] - M Elkashab, M Reizig, P D Greig, R Cameron, M J Phillips, S Chung, M Cattral, G Levy. Incidence and patterns of rejection using different induction therapies in liver transplant recipients.
Transplantation proceedings.
1994 Oct; 26(5):2669-71. doi:
NULL. [PMID: 7940835] - I Raz. Exocrine insufficiency in transplanted pancreas imitating pancreatic rejection.
Diabetes care.
1994 Jul; 17(7):779-80. doi:
10.2337/diacare.17.7.779. [PMID: 7523049] - M R Bye, A M Cairns-Bazarian, J M Ewig. Markedly reduced mortality associated with corticosteroid therapy of Pneumocystis carinii pneumonia in children with acquired immunodeficiency syndrome.
Archives of pediatrics & adolescent medicine.
1994 Jun; 148(6):638-41. doi:
10.1001/archpedi.1994.02170060092018. [PMID: 8193693] - T Kouno, T Egashira, F Takayama, Y Kudo, Y Yamanaka. Effect of methylprednisolone on plasma lipid peroxidation induced by lipopolysaccharide.
Japanese journal of pharmacology.
1994 Mar; 64(3):163-9. doi:
10.1254/jjp.64.163. [PMID: 8022118] - T A Uhler, D M Frim, P Pakzaban, O Isacson. The effects of megadose methylprednisolone and U-78517F on toxicity mediated by glutamate receptors in the rat neostriatum.
Neurosurgery.
1994 Jan; 34(1):122-7; discussion 127. doi:
". [PMID: 7907169]