3,3-DIMETHYL-1-BUTANOL (BioDeep_00000826186)
Volatile Flavor Compounds
代谢物信息卡片
化学式: C6H14O (102.10445940000001)
中文名称: 3,3-二甲基-1-丁醇
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(C)CCO
InChI: InChI=1S/C6H14O/c1-6(2,3)4-5-7/h7H,4-5H2,1-3H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Guodong Yang, Xiaoying Zhang. Trimethylamine N-oxide promotes hyperlipidemia acute pancreatitis via inflammatory response.
Canadian journal of physiology and pharmacology.
2022 Jan; 100(1):61-67. doi:
10.1139/cjpp-2021-0421. [PMID: 34793682] - Guangji Wang, Bin Kong, Wei Shuai, Hui Fu, Xiaobo Jiang, He Huang. 3,3-Dimethyl-1-butanol attenuates cardiac remodeling in pressure-overload-induced heart failure mice.
The Journal of nutritional biochemistry.
2020 04; 78(?):108341. doi:
10.1016/j.jnutbio.2020.108341. [PMID: 32004931] - Chien-Ning Hsu, Guo-Ping Chang-Chien, Sufan Lin, Chih-Yao Hou, You-Lin Tain. Targeting on Gut Microbial Metabolite Trimethylamine-N-Oxide and Short-Chain Fatty Acid to Prevent Maternal High-Fructose-Diet-Induced Developmental Programming of Hypertension in Adult Male Offspring.
Molecular nutrition & food research.
2019 09; 63(18):e1900073. doi:
10.1002/mnfr.201900073. [PMID: 31295767] - Xiaoyan Li, Yongcun Sun, Xinru Zhang, Jing Wang. Reductions in gut microbiota‑derived metabolite trimethylamine N‑oxide in the circulation may ameliorate myocardial infarction‑induced heart failure in rats, possibly by inhibiting interleukin‑8 secretion.
Molecular medicine reports.
2019 Jul; 20(1):779-786. doi:
10.3892/mmr.2019.10297. [PMID: 31180562] - Hui Chen, Jiabao Li, Ning Li, Hongsheng Liu, Jiyun Tang. Increased circulating trimethylamine N-oxide plays a contributory role in the development of endothelial dysfunction and hypertension in the RUPP rat model of preeclampsia.
Hypertension in pregnancy.
2019 May; 38(2):96-104. doi:
10.1080/10641955.2019.1584630. [PMID: 30821524] - Adam B Roberts, Xiaodong Gu, Jennifer A Buffa, Alex G Hurd, Zeneng Wang, Weifei Zhu, Nilaksh Gupta, Sarah M Skye, David B Cody, Bruce S Levison, William T Barrington, Matthew W Russell, Jodie M Reed, Ashraf Duzan, Jennifer M Lang, Xiaoming Fu, Lin Li, Alex J Myers, Suguna Rachakonda, Joseph A DiDonato, J Mark Brown, Valentin Gogonea, Aldons J Lusis, Jose Carlos Garcia-Garcia, Stanley L Hazen. Development of a gut microbe-targeted nonlethal therapeutic to inhibit thrombosis potential.
Nature medicine.
2018 09; 24(9):1407-1417. doi:
10.1038/s41591-018-0128-1. [PMID: 30082863] - Zeneng Wang, Adam B Roberts, Jennifer A Buffa, Bruce S Levison, Weifei Zhu, Elin Org, Xiaodong Gu, Ying Huang, Maryam Zamanian-Daryoush, Miranda K Culley, Anthony J DiDonato, Xiaoming Fu, Jennie E Hazen, Daniel Krajcik, Joseph A DiDonato, Aldons J Lusis, Stanley L Hazen. Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis.
Cell.
2015 Dec; 163(7):1585-95. doi:
10.1016/j.cell.2015.11.055. [PMID: 26687352] - P Barlow, R M Marchbanks. The effects of inhibiting choline dehydrogenase on choline metabolism in mice.
Biochemical pharmacology.
1985 Sep; 34(17):3117-22. doi:
10.1016/0006-2952(85)90156-x. [PMID: 3899120]