tiqueside (BioDeep_00000824899)
Chemicals and Drugs
代谢物信息卡片
化学式: C39H64O13 (740.4346694)
中文名称: 替奎安
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)CO)O)O)O)O)O)C)C)C)OC1
InChI: InChI=1S/C39H64O13/c1-18-7-12-39(47-17-18)19(2)28-25(52-39)14-24-22-6-5-20-13-21(8-10-37(20,3)23(22)9-11-38(24,28)4)48-35-33(46)31(44)34(27(16-41)50-35)51-36-32(45)30(43)29(42)26(15-40)49-36/h18-36,40-46H,5-17H2,1-4H3/t18-,19+,20+,21+,22-,23+,24+,25+,26-,27-,28+,29-,30+,31-,32-,33-,34-,35-,36+,37+,38+,39-/m1/s1
描述信息
C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent
C274 - Antineoplastic Agent > C1931 - Antineoplastic Plant Product > C823 - Saponin
C1907 - Drug, Natural Product
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- M Hernandez, J Montenegro, M Steiner, D Kim, C Sparrow, P A Detmers, S D Wright, Y S Chao. Intestinal absorption of cholesterol is mediated by a saturable, inhibitable transporter.
Biochimica et biophysica acta.
2000 Jul; 1486(2-3):232-42. doi:
10.1016/s1388-1981(00)00067-6. [PMID: 10903474] - L A Morehouse, F W Bangerter, M P DeNinno, P B Inskeep, P A McCarthy, J L Pettini, Y E Savoy, E D Sugarman, R W Wilkins, T C Wilson, H A Woody, L M Zaccaro, C E Chandler. Comparison of synthetic saponin cholesterol absorption inhibitors in rabbits: evidence for a non-stoichiometric, intestinal mechanism of action.
Journal of lipid research.
1999 Mar; 40(3):464-74. doi:
NULL. [PMID: 10064735] - W S Harris, C A Dujovne, S L Windsor, L L Gerrond, F A Newton, R A Gelfand. Inhibiting cholesterol absorption with CP-88,818 (beta-tigogenin cellobioside; tiqueside): studies in normal and hyperlipidemic subjects.
Journal of cardiovascular pharmacology.
1997 Jul; 30(1):55-60. doi:
10.1097/00005344-199707000-00008. [PMID: 9268221] - M J Avery, H G Fouda. Development of a high-performance liquid chromatographic-atmospheric pressure chemical ionization-tandem mass spectrometric assay for beta-tigogenin cellobioside in human serum.
Journal of chromatography. B, Biomedical sciences and applications.
1997 Feb; 689(2):365-70. doi:
10.1016/s0378-4347(96)00355-6. [PMID: 9080323] - H J Harwood, C E Chandler, L D Pellarin, F W Bangerter, R W Wilkins, C A Long, P G Cosgrove, M R Malinow, C A Marzetta, J L Pettini. Pharmacologic consequences of cholesterol absorption inhibition: alteration in cholesterol metabolism and reduction in plasma cholesterol concentration induced by the synthetic saponin beta-tigogenin cellobioside (CP-88818; tiqueside).
Journal of lipid research.
1993 Mar; 34(3):377-95. doi:
10.1016/s0022-2275(20)40730-8. [PMID: 8468523]