trimethylarsane oxide (BioDeep_00000821778)
代谢物信息卡片
化学式: C3H9AsO (135.9869324)
中文名称: 三甲基砷氧化物
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C[As](=O)(C)C
InChI: InChI=1S/C3H9AsO/c1-4(2,3)5/h1-3H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Mark Button, Iris Koch, Michael J Watts, Kenneth J Reimer. Arsenic speciation in the bracket fungus Fomitopsis betulina from contaminated and pristine sites.
Environmental geochemistry and health.
2020 Sep; 42(9):2723-2732. doi:
10.1007/s10653-019-00506-0
. [PMID: 31897873] - Simone Braeuer, Jan Borovička, Walter Goessler. A unique arsenic speciation profile in Elaphomyces spp. ("deer truffles")-trimethylarsine oxide and methylarsonous acid as significant arsenic compounds.
Analytical and bioanalytical chemistry.
2018 Mar; 410(9):2283-2290. doi:
10.1007/s00216-018-0903-3
. [PMID: 29430602] - Ivy Shiue. IgE antibodies and urinary trimethylarsine oxide accounted for 1-7\% population attributable risks for eczema in adults: USA NHANES 2005-2006.
Environmental science and pollution research international.
2015 Dec; 22(23):18404-9. doi:
10.1007/s11356-015-5084-4
. [PMID: 26233738] - Masato Kuramata, Futa Sakakibara, Ryota Kataoka, Tadashi Abe, Maki Asano, Koji Baba, Kazuhiro Takagi, Satoru Ishikawa. Arsenic biotransformation by Streptomyces sp. isolated from rice rhizosphere.
Environmental microbiology.
2015 Jun; 17(6):1897-909. doi:
10.1111/1462-2920.12572
. [PMID: 25039305] - Osama H Elshenawy, Ayman O S El-Kadi. Modulation of aryl hydrocarbon receptor regulated genes by acute administration of trimethylarsine oxide in the lung, kidney and heart of C57BL/6 mice.
Xenobiotica; the fate of foreign compounds in biological systems.
2015; 45(10):930-43. doi:
10.3109/00498254.2015.1032385
. [PMID: 26042454] - Ivy Shiue. Relationship of environmental exposures and ankylosing spondylitis and spinal mobility: US NHAENS, 2009-2010.
International journal of environmental health research.
2015; 25(3):322-9. doi:
10.1080/09603123.2014.945512
. [PMID: 25103950] - E M Kenyon, M F Hughes, B M Adair, J H Highfill, E A Crecelius, H J Clewell, J W Yager. Tissue distribution and urinary excretion of inorganic arsenic and its methylated metabolites in C57BL6 mice following subchronic exposure to arsenate in drinking water.
Toxicology and applied pharmacology.
2008 Nov; 232(3):448-55. doi:
10.1016/j.taap.2008.07.018
. [PMID: 18706920] - Blakely M Adair, Tanya Moore, Sean D Conklin, John T Creed, Douglas C Wolf, David J Thomas. Tissue distribution and urinary excretion of dimethylated arsenic and its metabolites in dimethylarsinic acid- or arsenate-treated rats.
Toxicology and applied pharmacology.
2007 Jul; 222(2):235-42. doi:
10.1016/j.taap.2007.04.012
. [PMID: 17559899] - Jun Shen, Hideki Wanibuchi, Michael P Waalkes, Elsayed I Salim, Anna Kinoshita, Kaoru Yoshida, Ginji Endo, Shoji Fukushima. A comparative study of the sub-chronic toxic effects of three organic arsenical compounds on the urothelium in F344 rats; gender-based differences in response.
Toxicology and applied pharmacology.
2006 Feb; 210(3):171-80. doi:
10.1016/j.taap.2005.04.018
. [PMID: 15950995] - E Dopp, L M Hartmann, U von Recklinghausen, A M Florea, S Rabieh, U Zimmermann, B Shokouhi, S Yadav, A V Hirner, A W Rettenmeier. Forced uptake of trivalent and pentavalent methylated and inorganic arsenic and its cyto-/genotoxicity in fibroblasts and hepatoma cells.
Toxicological sciences : an official journal of the Society of Toxicology.
2005 Sep; 87(1):46-56. doi:
10.1093/toxsci/kfi218
. [PMID: 15947026] - Stephen B Waters, Vicenta Devesa, Michael W Fricke, John T Creed, Miroslav Stýblo, David J Thomas. Glutathione modulates recombinant rat arsenic (+3 oxidation state) methyltransferase-catalyzed formation of trimethylarsine oxide and trimethylarsine.
Chemical research in toxicology.
2004 Dec; 17(12):1621-9. doi:
10.1021/tx0497853
. [PMID: 15606138] - Xiufen Lu, Lora L Arnold, Samuel M Cohen, William R Cullen, X Chris Le. Speciation of dimethylarsinous acid and trimethylarsine oxide in urine from rats fed with dimethylarsinic acid and dimercaptopropane sulfonate.
Analytical chemistry.
2003 Dec; 75(23):6463-8. doi:
10.1021/ac034868u
. [PMID: 14640715] - Jun Shen, Hideki Wanibuchi, Elsayed I Salim, Min Wei, Anna Kinoshita, Kaoru Yoshida, Ginji Endo, Shoji Fukushima. Liver tumorigenicity of trimethylarsine oxide in male Fischer 344 rats--association with oxidative DNA damage and enhanced cell proliferation.
Carcinogenesis.
2003 Nov; 24(11):1827-35. doi:
10.1093/carcin/bgg143
. [PMID: 12919961] - Michael F Hughes, Elaina M Kenyon, Brenda C Edwards, Carol T Mitchell, Luz Maria Del Razo, David J Thomas. Accumulation and metabolism of arsenic in mice after repeated oral administration of arsenate.
Toxicology and applied pharmacology.
2003 Sep; 191(3):202-10. doi:
10.1016/s0041-008x(03)00249-7
. [PMID: 13678653] - B Wlodarczyk, O Spiegelstein, J Gelineau-van Waes, R L Vorce, X Lu, C X Le, R H Finnell. Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice.
Toxicology and applied pharmacology.
2001 Dec; 177(3):238-46. doi:
10.1006/taap.2001.9303
. [PMID: 11749123] - J H Becker, J S Willis. Properties of Na-K pump in primary cultures of kidney cells.
Journal of cellular physiology.
1979 Jun; 99(3):427-39. doi:
10.1002/jcp.1040990317
. [PMID: 222786]