L-Leucine-p-nitroanilide (BioDeep_00000821328)
代谢物信息卡片
化学式: C12H17N3O3 (251.127)
中文名称: L-亮氨酸-4-硝基苯胺(Leu-pNA)
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)CC(C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])N
InChI: InChI=1S/C12H17N3O3/c1-8(2)7-11(13)12(16)14-9-3-5-10(6-4-9)15(17)18/h3-6,8,11H,7,13H2,1-2H3,(H,14,16)/t11-/m0/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Purushottam R Lomate, Vandana K Hivrale. Changes and induction of aminopeptidase activities in response to pathogen infection during germination of pigeonpea (Cajanas cajan) seeds.
Journal of plant physiology.
2011 Oct; 168(15):1735-42. doi:
10.1016/j.jplph.2011.05.002. [PMID: 21640431] - Linda J Gahan, Yannick Pauchet, Heiko Vogel, David G Heckel. An ABC transporter mutation is correlated with insect resistance to Bacillus thuringiensis Cry1Ac toxin.
PLoS genetics.
2010 Dec; 6(12):e1001248. doi:
10.1371/journal.pgen.1001248. [PMID: 21187898] - O V Kalinichenko, T M Myshunina, M D Tron'ko. [B-, H- and L-cathepsin-like activity in blood plasma of patients with diseases of the thyroid, parathyroid and adrenal glands].
Ukrains'kyi biokhimichnyi zhurnal (1999 ).
2010 Mar; 82(2):53-8. doi:
NULL. [PMID: 20684245] - Ruth Landau, Alexandra Laverrière, Paul Bischof, Olivier Irion, Michel Morales, Marie Cohen. Alteration of circulating Placental Leucine Aminopeptidase (P-LAP) activity in preeclampsia.
Neuro endocrinology letters.
2010; 31(1):63-6. doi:
. [PMID: 20150869] - Natasa Bozić, Zoran Vujcić. Detection and quantification of leucyl aminopeptidase after native electrophoresis using leucine-p-nitroanilide.
Electrophoresis.
2005 Jun; 26(12):2476-80. doi:
10.1002/elps.200500047. [PMID: 15920779] - Heidi Demaegdt, Patrick Vanderheyden, Jean-Paul De Backer, Sabrina Mosselmans, Hilde Laeremans, Minh Tam Le, Veerle Kersemans, Yvette Michotte, Georges Vauquelin. Endogenous cystinyl aminopeptidase in Chinese hamster ovary cells: characterization by [125I]Ang IV binding and catalytic activity.
Biochemical pharmacology.
2004 Sep; 68(5):885-92. doi:
10.1016/j.bcp.2004.05.047. [PMID: 15294451] - W Bawab, E Querido, P Crine, L DesGroseillers. Identification and characterization of aminopeptidases from Aplysia californica.
The Biochemical journal.
1992 Sep; 286 ( Pt 3)(?):967-75. doi:
10.1042/bj2860967. [PMID: 1417757] - W Hornebeck, R Homsy, M Ayrault-Jarrier, L Stanislavski, L Robert. Characterization of metalloelastase-like activity from the plasma of a patient with Tangier disease.
Biological chemistry Hoppe-Seyler.
1991 Dec; 372(12):1057-64. doi:
10.1515/bchm3.1991.372.2.1057. [PMID: 1789930] - J Zenka, J Prokopic. Aminopeptidase inhibitor from Ascaris suum.
Folia parasitologica.
1985; 32(3):247-53. doi:
NULL. [PMID: 4043864] - S H Lin, H E Van Wart. Effect of cryosolvents and subzero temperatures on the hydrolysis of L-leucine-p-nitroanilide by porcine kidney leucine aminopeptidase.
Biochemistry.
1982 Oct; 21(22):5528-33. doi:
10.1021/bi00265a023. [PMID: 7171573] - L Andersson, T C Isley, R Wolfenden. alpha-aminoaldehydes: transition state analogue inhibitors of leucine aminopeptidase.
Biochemistry.
1982 Aug; 21(17):4177-80. doi:
10.1021/bi00260a040. [PMID: 7126535] - A C Roy, M Yeang, S M Karim. pH dependent inhibition of serum oxytocinase activity by prostaglandins and cyclic GMP.
Prostaglandins, leukotrienes, and medicine.
1982 Feb; 8(2):173-9. doi:
10.1016/s0262-1746(82)80010-3. [PMID: 6281812] - B B Rankin, T M McIntyre, N P Curthoys. Brush border membrane hydrolysis of S-benzyl-cysteine-p-nitroanilide, and activity of aminopeptidase M.
Biochemical and biophysical research communications.
1980 Oct; 96(3):991-6. doi:
10.1016/0006-291x(80)90050-9. [PMID: 6108111]
