Umirolimus (BioDeep_00000819306)
代谢物信息卡片
化学式: C55H87NO14 (985.6126241999999)
中文名称: Umirolimus
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOCCOC1CCC(CC1OC)CC(C)C2CC(=O)C(C=C(C(C(C(=O)C(CC(C=CC=CC=C(C(CC3CCC(C(O3)(C(=O)C(=O)N4CCCCC4C(=O)O2)O)C)OC)C)C)C)OC)O)C)C
InChI: InChI=1S/C55H87NO14/c1-12-67-26-27-68-45-24-22-41(31-48(45)65-10)30-37(5)47-33-44(57)36(4)29-39(7)50(59)51(66-11)49(58)38(6)28-34(2)18-14-13-15-19-35(3)46(64-9)32-42-23-21-40(8)55(63,70-42)52(60)53(61)56-25-17-16-20-43(56)54(62)69-47/h13-15,18-19,29,34,36-38,40-43,45-48,50-51,59,63H,12,16-17,20-28,30-33H2,1-11H3/b15-13+,18-14+,35-19+,39-29+/t34-,36-,37-,38-,40-,41+,42+,43+,45-,46+,47+,48-,50-,51+,55-/m1/s1
描述信息
D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents
D000893 - Anti-Inflammatory Agents
C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C61074 - Serine/Threonine Kinase Inhibitor
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C2201 - mTOR Inhibitor
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant
同义名列表
2 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:177399
- PubChem: 23230457
- PubChem: 11158972
- DrugBank: DB15527
- ChEMBL: CHEMBL2107380
- CAS: 851536-75-9
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mauro Chiarito, Matteo Sturla, Carlo Briguori, Massimo Mancone, Corrado Tamburino, Franco Fabbiocchi, Daniela Trabattoni, Fabrizio Tomai, Anita Paggi, Gaetano Gioffrè, Rocco Sclafani, Arturo Giordano, Giulio G Stefanini, Gennaro Sardella. Polymer-free biolimus-A9-eluting stent performance according to renal impairment: insights from the RUDI-FREE registry.
Journal of cardiovascular medicine (Hagerstown, Md.).
2022 02; 23(2):127-134. doi:
10.2459/jcm.0000000000001269. [PMID: 34632982] - Shintaro Takamura, Nobuaki Suzuki, Ruri Ishibashi, Nozomu Yukimitsu, Kazuya Sasaki, Yukiko Terada, Hideyuki Kawashima, Hiroyuki Kyono, Ken Kozuma. Long-Term Clinical and Angiographic Outcomes After Implantation of New-Generation Drug-Eluting Stents for Patients on Maintenance Hemodialysis.
International heart journal.
2019 May; 60(3):521-526. doi:
10.1536/ihj.18-359. [PMID: 31105145] - Tim Kinnaird, Fairoz Abdul, Ahmed Hailan, Azeem Sheikh, Jonathan Hinton, Khaled Yazji, Senthil Elangovan, Adnan Yousef, Sean Gallagher, Anirban Choudhury, Richard Anderson, Peter O'Kane, David Smith. Twelve-month outcomes of patients unsuitable for prolonged DAPT presenting with an acute coronary syndrome and treated with polymer-free biolimus A9 drug-coated stents.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.
2018 12; 92(7):1220-1228. doi:
10.1002/ccd.27722. [PMID: 30244504] - Cosmo Godino, Carlo Andrea Pivato, Mauro Chiarito, Michael Donahue, Luca Testa, Riccardo Colantonio, Alberto Cappelletti, Diego Milazzo, Rosario Parisi, Annamaria Nicolino, Shahram Moshiri, Gianfranco Aprigliano, Altin Palloshi, Dennis Zavalloni Parenti, David Rutigliano, Nicola Locuratolo, Francesco Melillo, Andrea Scotti, Luca Arrigoni, Matteo Montorfano, Rossella Fattori, Patrizia Presbitero, Gennaro Sardella, Francesco Bedogni, Alberto Margonato, Carlo Briguori, Antonio Colombo. Polymer-free amphilimus-eluting stent versus biodegradable polymer biolimus-eluting stent in patients with and without diabetes mellitus.
International journal of cardiology.
2017 Oct; 245(?):69-76. doi:
10.1016/j.ijcard.2017.06.028. [PMID: 28874301] - Philippe Garot, Marie-Claude Morice, Damras Tresukosol, Stuart J Pocock, Ian T Meredith, Alexandre Abizaid, Didier Carrié, Christoph Naber, Andres Iñiguez, Suneel Talwar, Ian B A Menown, Evald H Christiansen, John Gregson, Samuel Copt, Thomas Hovasse, Philipp Lurz, Luc Maillard, Florian Krackhardt, Paul Ong, Jonathan Byrne, Simon Redwood, Ute Windhövel, Samantha Greene, Hans-Peter Stoll, Philip Urban. 2-Year Outcomes of High Bleeding Risk Patients After Polymer-Free Drug-Coated Stents.
Journal of the American College of Cardiology.
2017 Jan; 69(2):162-171. doi:
10.1016/j.jacc.2016.10.009. [PMID: 27806919] - Gian Battista Danzi, Raffaele Piccolo, Bernard Chevalier, Philip Urban, Farzin Fath-Ordoubadi, Didier Carrie, Marcus Wiemer, Antonio Serra, William Wijns, Petr Kala, Amerigo Stabile, Javier Goicolea Ruigomez, Dragan Sagic, Peep Laanmets, Gerhard Strupp, Nick West. Five-year clinical performance of a biodegradable polymer-coated biolimus-eluting stent in unselected patients.
Heart (British Cardiac Society).
2017 01; 103(2):111-116. doi:
10.1136/heartjnl-2016-309283. [PMID: 27511446] - David Martí, Edurne López, Salvador Álvarez, Jorge Palazuelos, Ignacio Rada, Fernando Alfonso. Neoatherosclerosis causing occlusive in-stent restenosis: Impact of intracoronary imaging in the intensity of lipid-lowering therapy.
Cardiovascular revascularization medicine : including molecular interventions.
2016 Dec; 17(8):584-585. doi:
10.1016/j.carrev.2016.09.013. [PMID: 27743816] - Tim Kinnaird, Mehmood Butt, Fairoz Abdul, Khaled Yazji, Ahmed Hailan, Sean Gallagher, Nicholas Ossei-Gerning, Alexander Chase, Anirban Choudhury, David Smith, Richard Anderson. Early Clinical Experience with a Polymer-Free Biolimus A9 Drug-Coated Stent in DES-Type Patients Who Are Poor Candidates for Prolonged Dual Anti-Platelet Therapy.
PloS one.
2016; 11(6):e0157812. doi:
10.1371/journal.pone.0157812. [PMID: 27362841] - Cosmo Godino, Dennis Zavalloni Parenti, Damiano Regazzoli, David Rutigliano, Luigi Lucisano, Giacomo Maria Viani, Marco Spartera, Alaide Chieffo, Michael Donahue, Alberto Cappelletti, Nicola Locuratolo, Rosario Parisi, Rossella Fattori, Patrizia Presbitero, Alberto Margonato, Carlo Briguori, Gennaro Sardella, Antonio Colombo. One-year outcome of biolimus eluting stent with biodegradable polymer in all comers: the Italian Nobori Stent Prospective Registry.
International journal of cardiology.
2014 Nov; 177(1):11-6. doi:
10.1016/j.ijcard.2014.09.019. [PMID: 25499324] - Shoichi Kuramitsu, Shinjo Sonoda, Hiroyoshi Yokoi, Masashi Iwabuchi, Yuji Nishizaki, Tomohiro Shinozaki, Takenori Domei, Makoto Hyodo, Katsumi Inoue, Shinichi Shirai, Kenji Ando, Masakiyo Nobuyoshi. Long-term coronary arterial response to biodegradable polymer biolimus-eluting stents in comparison with durable polymer sirolimus-eluting stents and bare-metal stents: five-year follow-up optical coherence tomography study.
Atherosclerosis.
2014 Nov; 237(1):23-9. doi:
10.1016/j.atherosclerosis.2014.08.031. [PMID: 25190308] - Juan Luis Gutiérrez-Chico, Peter Jüni, Héctor M García-García, Evelyn Regar, Eveline Nüesch, Francesco Borgia, Willem J van der Giessen, Simon Davies, Robert Jan van Geuns, Gioel Gabrio Secco, Susanne Meis, Stephan Windecker, Patrick W Serruys, Carlo di Mario. Long-term tissue coverage of a biodegradable polylactide polymer-coated biolimus-eluting stent: comparative sequential assessment with optical coherence tomography until complete resorption of the polymer.
American heart journal.
2011 Nov; 162(5):922-31. doi:
10.1016/j.ahj.2011.09.005. [PMID: 22093210]