Arg-3-hyp-7-phe-bradykinin (BioDeep_00000815819)
代谢物信息卡片
化学式: C60H87N19O13 (1281.6730412000002)
中文名称: (D-ARG0,HYP3,D-PHE7)-BRADYKININ
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC(N(C1)C(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)N)C(=O)N2CC(CC2C(=O)NCC(=O)NC(CC3=CC=CC=C3)C(=O)NC(CO)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCCN=C(N)N)C(=O)O)O
InChI: InChI=1S/C60H87N19O13/c61-39(20-10-24-68-58(62)63)49(83)73-40(21-11-25-69-59(64)65)55(89)78-27-13-23-46(78)56(90)79-33-38(81)31-47(79)54(88)71-32-48(82)72-42(28-35-14-4-1-5-15-35)50(84)77-45(34-80)53(87)76-44(30-37-18-8-3-9-19-37)52(86)75-43(29-36-16-6-2-7-17-36)51(85)74-41(57(91)92)22-12-26-70-60(66)67/h1-9,14-19,38-47,80-81H,10-13,20-34,61H2,(H,71,88)(H,72,82)(H,73,83)(H,74,85)(H,75,86)(H,76,87)(H,77,84)(H,91,92)(H4,62,63,68)(H4,64,65,69)(H4,66,67,70)/t38-,39-,40+,41+,42+,43+,44-,45+,46+,47+/m1/s1
描述信息
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
同义名列表
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- H Sylvin, I van der Ploeg, K Alving. The effect of a bradykinin B2 receptor antagonist, NPC-567, on allergen-induced airway responses in a porcine model.
Inflammation research : official journal of the European Histamine Research Society ... [et al.].
2001 Sep; 50(9):453-9. doi:
10.1007/pl00000270. [PMID: 11603850] - B Miskowiak, P Rebuffat, G G Nussdorfer, L K Malendowicz. Bradykinin and pituitary-adrenocortical function in the rabbit: in vitro and in vivo studies.
Endocrine research.
1999 May; 25(2):139-51. doi:
10.1080/07435809909066136. [PMID: 10382676] - L K Malendowicz, C Macchi, G G Nussdorfer, A Markowska. Effects of the prolonged administration of bradykinin on the rat pituitary-adrenocortical axis.
Histology and histopathology.
1996 Jul; 11(3):641-5. doi:
NULL. [PMID: 8839754] - C C Deck, M A Gaballa, T E Raya. Relative contribution of angiotensin II, bradykinin, and prostaglandins to the renal effects of converting enzyme inhibition in rats after chronic myocardial infarction.
Journal of cardiovascular pharmacology.
1996 Jul; 28(1):167-74. doi:
10.1097/00005344-199607000-00024. [PMID: 8797151] - A A Khan, S N Raja, D C Manning, J N Campbell, R A Meyer. The effects of bradykinin and sequence-related analogs on the response properties of cutaneous nociceptors in monkeys.
Somatosensory & motor research.
1992; 9(2):97-106. doi:
10.3109/08990229209144765. [PMID: 1323902] - J L Ader, F Praddaude, T Tran-Van, C Emond, I Tack, D Regoli, J P Girolami. Direct effects of bradykinin on glomerular filtration and proximal tubule reabsorption in rat kidney.
Agents and actions. Supplements.
1992; 38 ( Pt 3)(?):128-33. doi:
NULL. [PMID: 1462854] - W M Abraham. The potential role of bradykinin antagonists in the treatment of asthma.
Agents and actions. Supplements.
1992; 38 ( Pt 3)(?):439-49. doi:
". [PMID: 1462878] - J A Pongracic, R M Naclerio, C J Reynolds, D Proud. A competitive kinin receptor antagonist, [DArg0, Hyp3, DPhe7]-bradykinin, does not affect the response to nasal provocation with bradykinin.
British journal of clinical pharmacology.
1991 Mar; 31(3):287-94. doi:
10.1111/j.1365-2125.1991.tb05532.x. [PMID: 1647192] - A H Costello, K M Hargreaves. Suppression of carrageenan-induced hyperalgesia, hyperthermia and edema by a bradykinin antagonist.
European journal of pharmacology.
1989 Nov; 171(2-3):259-63. doi:
10.1016/0014-2999(89)90118-0. [PMID: 2482813]