Tenatoprazole (BioDeep_00000815659)

   


代谢物信息卡片


Tenatoprazole

化学式: C16H18N4O3S (346.1099558000001)
中文名称: 泰妥拉唑
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=CC(=N3)OC
InChI: InChI=1S/C16H18N4O3S/c1-9-7-17-12(10(2)14(9)23-4)8-24(21)16-18-11-5-6-13(22-3)19-15(11)20-16/h5-7H,8H2,1-4H3,(H,18,19,20)

描述信息

C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent > C29723 - Proton Pump Inhibitor

同义名列表

1 个代谢物同义名

Tenatoprazole



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Anne T Nies, Ute Hofmann, Claudia Resch, Elke Schaeffeler, Maria Rius, Matthias Schwab. Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs). PloS one. 2011; 6(7):e22163. doi: 10.1371/journal.pone.0022163. [PMID: 21779389]
  • George Sachs, Jai Moo Shin, Richard Hunt. Novel approaches to inhibition of gastric acid secretion. Current gastroenterology reports. 2010 Dec; 12(6):437-47. doi: 10.1007/s11894-010-0149-5. [PMID: 20924727]
  • Jin Guan, Jing Yang, Jingjing Li, Xiaohong Li, Famei Li. Determination of tenatoprazole enantiomers and their enantioselective pharmacokinetics in rats. Chirality. 2009 Jun; 21(6):613-8. doi: 10.1002/chir.20657. [PMID: 18752288]
  • Ramakrishna Nirogi, Vishwottam Kandikere, Koteshwara Mudigonda, Gopinadh Bhyrapuneni. Quantification of tenatoprazole in rat plasma by HPLC: validation and its application to pharmacokinetic studies. Biomedical chromatography : BMC. 2007 Dec; 21(12):1240-4. doi: 10.1002/bmc.875. [PMID: 17590865]
  • Pei Liu, Bo Sun, Xiumei Lu, Feng Qin, Famei Li. HPLC determination and pharmacokinetic study of tenatoprazole in dog plasma after oral administration of enteric-coated capsule. Biomedical chromatography : BMC. 2007 Jan; 21(1):89-93. doi: 10.1002/bmc.724. [PMID: 17080510]
  • G Sachs, J M Shin, C W Howden. Review article: the clinical pharmacology of proton pump inhibitors. Alimentary pharmacology & therapeutics. 2006 Jun; 23 Suppl 2(?):2-8. doi: 10.1111/j.1365-2036.2006.02943.x. [PMID: 16700898]
  • A B R Thomson, P Cohen, H Ficheux, P Fiorentini, F Domagala, M Homerin, A Taccoen. Comparison of the effects of fasting morning, fasting evening and fed bedtime administration of tenatoprazole on intragastric pH in healthy volunteers: a randomized three-way crossover study. Alimentary pharmacology & therapeutics. 2006 Apr; 23(8):1179-87. doi: 10.1111/j.1365-2036.2006.02781.x. [PMID: 16611279]
  • Jai Moo Shin, Michel Homerin, Florence Domagala, Hervé Ficheux, George Sachs. Characterization of the inhibitory activity of tenatoprazole on the gastric H+,K+ -ATPase in vitro and in vivo. Biochemical pharmacology. 2006 Mar; 71(6):837-49. doi: 10.1016/j.bcp.2005.11.030. [PMID: 16405921]
  • Florence Domagala, Hervé Ficheux, Georges Houin, Jérôme Barré. Pharmacokinetics of tenatoprazole, a newly synthesized proton pump inhibitor, in healthy male Caucasian volunteers. Arzneimittel-Forschung. 2006; 56(1):33-9. doi: 10.1055/s-0031-1296698. [PMID: 16478003]
  • Richard H Hunt, David Armstrong, Cindy James, Sadat K Chowdhury, Yuhong Yuan, Paola Fiorentini, Alain Taccoen, Patrick Cohen. Effect on intragastric pH of a PPI with a prolonged plasma half-life: comparison between tenatoprazole and esomeprazole on the duration of acid suppression in healthy male volunteers. The American journal of gastroenterology. 2005 Sep; 100(9):1949-56. doi: 10.1111/j.1572-0241.2005.41956.x. [PMID: 16128938]
  • J P Galmiche, S Sacher-Huvelin, S Bruley des Varannes, F Vavasseur, A Taccoen, P Fiorentini, M Homerin. A comparative study of the early effects of tenatoprazole 40 mg and esomeprazole 40 mg on intragastric pH in healthy volunteers. Alimentary pharmacology & therapeutics. 2005 Mar; 21(5):575-82. doi: 10.1111/j.1365-2036.2005.02381.x. [PMID: 15740541]
  • J P Galmiche, S Bruley Des Varannes, P Ducrotté, S Sacher-Huvelin, F Vavasseur, A Taccoen, P Fiorentini, M Homerin. Tenatoprazole, a novel proton pump inhibitor with a prolonged plasma half-life: effects on intragastric pH and comparison with esomeprazole in healthy volunteers. Alimentary pharmacology & therapeutics. 2004 Mar; 19(6):655-62. doi: 10.1111/j.1365-2036.2004.01893.x. [PMID: 15023167]