Sodium propionate hydrate (BioDeep_00000815435)
代谢物信息卡片
化学式: C3H7NaO3 (114.0292872)
中文名称: 丙酸钠水合物
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC(=O)[O-].O.[Na+]
InChI: +1
数据库引用编号
5 个数据库交叉引用编号
- PubChem: 23663426
- DrugBank: DB13440
- ChEMBL: CHEMBL3989705
- CAS: 170929-20-1
- CAS: 6700-17-0
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Li Luo, Huafeng Zhang, Weiliang Chen, Ziming Zheng, Zihao He, Haoyu Wang, Kaiping Wang, Yu Zhang. Angelica sinensis polysaccharide ameliorates nonalcoholic fatty liver disease via restoring estrogen-related receptor α expression in liver.
Phytotherapy research : PTR.
2023 Aug; ?(?):. doi:
10.1002/ptr.7982
. [PMID: 37563852] - Ehsan Ahmadifar, Mahboubeh Eslami, Naser Kalhor, Amine Zaretabar, Sedigheh Mohammadzadeh, Mohsen Shahriari Moghadam, Morteza Yousefi, Mehdi Ahmadifar, Seyed Hossein Hoseinifar, Tonapha Pusadee, Hien van Doan. Effect of a diet enriched with sodium propionate on growth performance, antioxidant property, innate-adaptive immune response, and growth-related genes expression in critically endangered beluga sturgeon (Huso huso).
Fish & shellfish immunology.
2022 Jun; 125(?):101-108. doi:
10.1016/j.fsi.2022.04.031
. [PMID: 35472403] - V Brauckmann, S Nambiar, A Potthoff, S Höxtermann, J Wach, A Kayser, C Tiemann, A K Schuppe, N H Brockmeyer, A Skaletz-Rorowski. Influence of dietary supplementation of short-chain fatty acid sodium propionate in people living with HIV (PLHIV).
Journal of the European Academy of Dermatology and Venereology : JEADV.
2022 Jun; 36(6):881-889. doi:
10.1111/jdv.18006
. [PMID: 35176190] - Mingjuan Deng, Fang Qu, Long Chen, Chang Liu, Ming Zhang, Fazheng Ren, Huiyuan Guo, Hao Zhang, Shaoyang Ge, Chaodong Wu, Liang Zhao. SCFAs alleviated steatosis and inflammation in mice with NASH induced by MCD.
The Journal of endocrinology.
2020 06; 245(3):425-437. doi:
10.1530/joe-20-0018
. [PMID: 32302970] - Jinjin Zhang, Hui Zhang, Miao Liu, Yawen Lan, Huiyuan Sun, Kangsen Mai, Min Wan. Short-Chain Fatty Acids Promote Intracellular Bactericidal Activity in Head Kidney Macrophages From Turbot (Scophthalmus maximus L.) via Hypoxia Inducible Factor-1α.
Frontiers in immunology.
2020; 11(?):615536. doi:
10.3389/fimmu.2020.615536
. [PMID: 33424870] - Kaifan Yu, Yanan Zhang, Huizi Chen, Weiyun Zhu. Hepatic Metabolomic and Transcriptomic Responses Induced by Cecal Infusion of Sodium Propionate in a Fistula Pig Model.
Journal of agricultural and food chemistry.
2019 Nov; 67(47):13073-13081. doi:
10.1021/acs.jafc.9b05070
. [PMID: 31675219] - B Song, Y Z Zhong, C B Zheng, F N Li, Y H Duan, J P Deng. Propionate alleviates high-fat diet-induced lipid dysmetabolism by modulating gut microbiota in mice.
Journal of applied microbiology.
2019 Nov; 127(5):1546-1555. doi:
10.1111/jam.14389
. [PMID: 31325215] - A Bedford, L Beckett, K Hardin, N W Dias, T Davis, V R G Mercadante, A D Ealy, R R White. Propionate Affects Insulin Signaling and Progesterone Profiles in Dairy Heifers.
Scientific reports.
2018 12; 8(1):17629. doi:
10.1038/s41598-018-35977-1
. [PMID: 30514961] - Edward S Chambers, Claire S Byrne, Karen Aspey, Yanjie Chen, Saadiyah Khan, Douglas J Morrison, Gary Frost. Acute oral sodium propionate supplementation raises resting energy expenditure and lipid oxidation in fasted humans.
Diabetes, obesity & metabolism.
2018 04; 20(4):1034-1039. doi:
10.1111/dom.13159
. [PMID: 29134744] - Dong Li, Shi-Xun Zhao, Jun-An Wang, Jin-Feng Zhu, Hong-Wei Guan, Jie Zhang. [Effect of Carbon Source on Lab-scale SAD Process in a Wastewater Treatment Plant].
Huan jing ke xue= Huanjing kexue.
2018 Jan; 39(1):232-238. doi:
10.13227/j.hjkx.201706279
. [PMID: 29965687] - U Agarwal, Q Hu, B J Bequette. Propionate supplementation improves nitrogen use by reducing urea flux in sheep.
Journal of animal science.
2015 Oct; 93(10):4883-90. doi:
10.2527/jas.2015-9226
. [PMID: 26523581] - S Li, K Yuan, L K Mamedova, G B Penner, M Oba, K A Beauchemin, B J Bradford. High-grain diets suppress ruminal tissue abundance of angiopoietin-like protein 4 in cattle.
Journal of animal science.
2014 Sep; 92(9):4077-85. doi:
10.2527/jas.2013-7316
. [PMID: 25085388] - T Yajima, R Inoue, M Yajima, T Tsuruta, S Karaki, T Hira, A Kuwahara. The G-protein on cholesterol-rich membrane microdomains mediates mucosal sensing of short- chain fatty acid and secretory response in rat colon.
Acta physiologica (Oxford, England).
2011 Nov; 203(3):381-9. doi:
10.1111/j.1748-1716.2011.02331.x
. [PMID: 21649864] - S Mohapatra, N P Sahu, A K Pal, A K Prusty, Vikas Kumar, Shivendra Kumar. Haemato-immunology and histo-architectural changes in Labeo rohita fingerlings: effect of dietary aflatoxin and mould inhibitor.
Fish physiology and biochemistry.
2011 Mar; 37(1):177-86. doi:
10.1007/s10695-010-9428-1
. [PMID: 20803068] - Silvia A Valencia-Chamorro, María B Pérez-Gago, Miguel A Del Río, Lluís Palou. Effect of antifungal hydroxypropyl methylcellulose-lipid edible composite coatings on Penicillium decay development and postharvest quality of cold-stored 'Ortanique' mandarins.
Journal of food science.
2010 Oct; 75(8):S418-26. doi:
10.1111/j.1750-3841.2010.01801.x
. [PMID: 21535515] - Annette Thierauf, Annerose Serr, Claudia C Halter, Ali Al-Ahmad, Sumandeep Rana, Wolfgang Weinmann. Influence of preservatives on the stability of ethyl glucuronide and ethyl sulphate in urine.
Forensic science international.
2008 Nov; 182(1-3):41-5. doi:
10.1016/j.forsciint.2008.09.011
. [PMID: 18986786] - Barry J Bradford, Michael S Allen. Phlorizin administration does not attenuate hypophagia induced by intraruminal propionate infusion in lactating dairy cattle.
The Journal of nutrition.
2007 Feb; 137(2):326-30. doi:
10.1093/jn/137.2.326
. [PMID: 17237306] - Kerry B Goralski, Ratna Bose, Daniel S Sitar. NH4+ modulates renal tubule amantadine transport independently of intracellular pH changes.
European journal of pharmacology.
2006 Jul; 541(1-2):87-94. doi:
10.1016/j.ejphar.2006.04.051
. [PMID: 16750190] - Barry J Bradford, Alicia D Gour, Amy S Nash, Michael S Allen. Propionate challenge tests have limited value for investigating bovine metabolism.
The Journal of nutrition.
2006 Jul; 136(7):1915-20. doi:
10.1093/jn/136.7.1915
. [PMID: 16772459] - D L Smith, B M Stinefelt, K P Blemings, M E Wilson. Diet-induced alterations in progesterone clearance appear to be mediated by insulin signaling in hepatocytes.
Journal of animal science.
2006 May; 84(5):1102-9. doi:
10.2527/2006.8451102x
. [PMID: 16612012] - Barry J Bradford, Masahito Oba, Richard A Ehrhardt, Yves R Boisclair, Michael S Allen. Propionate is not an important regulator of plasma leptin concentration in dairy cattle.
Domestic animal endocrinology.
2006 Feb; 30(2):65-75. doi:
10.1016/j.domaniend.2005.05.007
. [PMID: 16002256] - M Oba, M S Allen. Dose-response effects of intrauminal infusion of propionate on feeding behavior of lactating cows in early or midlactation.
Journal of dairy science.
2003 Sep; 86(9):2922-31. doi:
10.3168/jds.s0022-0302(03)73889-2
. [PMID: 14507028] - Thomas A Heming, Nataliya N Bulayeva, Akhil Bidani. Cell alkalosis elevates cytosolic Ca2+ in rabbit resident alveolar macrophages.
Clinical science (London, England : 1979).
2003 Jul; 105(1):21-8. doi:
10.1042/cs20030004
. [PMID: 12593669] - Yoshio Fujioka, Miho Masai, Sayaka Tsuboi, Takahiro Okumura, Shinji Morimoto, Takeshi Tsujino, Mitsumasa Ohyanagi, Tadaaki Iwasaki. Troglitazone reduces activity of the Na+/H+ exchanger in fructose-fed borderline hypertensive rats.
Hypertension research : official journal of the Japanese Society of Hypertension.
2003 Jan; 26(1):111-6. doi:
10.1291/hypres.26.111
. [PMID: 12661920] - D R Bigner, J P Goff, M A Faust, H D Tyler, R L Horst. Comparison of oral sodium compounds for the correction of acidosis.
Journal of dairy science.
1997 Sep; 80(9):2162-6. doi:
10.3168/jds.s0022-0302(97)76163-0
. [PMID: 9313160] - Y Yamaji, H Tsuganezawa, O W Moe, R J Alpern. Intracellular acidosis activates c-Src.
The American journal of physiology.
1997 Mar; 272(3 Pt 1):C886-93. doi:
10.1152/ajpcell.1997.272.3.c886
. [PMID: 9124524] - T M Wolever, P J Spadafora, S C Cunnane, P B Pencharz. Propionate inhibits incorporation of colonic [1,2-13C]acetate into plasma lipids in humans.
The American journal of clinical nutrition.
1995 Jun; 61(6):1241-7. doi:
10.1093/ajcn/61.6.1241
. [PMID: 7762524] - Y Kishimoto, S Wakabayashi, H Takeda. Effects of intravenous injection and intraperitoneal continual administration of sodium propionate on serum cholesterol levels in rats.
Journal of nutritional science and vitaminology.
1995 Feb; 41(1):73-81. doi:
10.3177/jnsv.41.73
. [PMID: 7616328] - R L Ornberg, S Furuya, G Goping, G A Kuijpers. Granule swelling in stimulated bovine adrenal chromaffin cells: regulation by internal granule pH.
Cell and tissue research.
1995 Jan; 279(1):85-92. doi:
10.1007/bf00300694
. [PMID: 7895265] - M Wehling, J Käsmayr, M Christ, W Sippell, K Theisen, O A Müller. The early mineralocorticoid effector mechanism, the sodium-proton exchanger, is sensitized in lymphocytes from patients with Cushing's syndrome.
Clinical endocrinology.
1992 Sep; 37(3):260-5. doi:
10.1111/j.1365-2265.1992.tb02320.x
. [PMID: 1330384] - D Bödeker, H Martens. Elevated urinary excretion of orotic acid in sheep caused by intraruminal infusion of sodium propionate.
Comparative biochemistry and physiology. B, Comparative biochemistry.
1992 Jun; 102(2):231-4. doi:
10.1016/0305-0491(92)90115-8
. [PMID: 1617933] - T Todesco, A V Rao, O Bosello, D J Jenkins. Propionate lowers blood glucose and alters lipid metabolism in healthy subjects.
The American journal of clinical nutrition.
1991 Nov; 54(5):860-5. doi:
10.1093/ajcn/54.5.860
. [PMID: 1951157] - J Koppel, S Kuchár, S Mozes, K Boda. Plasma insulin and glucose in suckling and ruminating lambs after peroral administration of glucose and propionate.
Experimental and clinical endocrinology.
1988 Dec; 92(2):238-40. doi:
10.1055/s-0029-1210808
. [PMID: 3072215] - Y Gröhn, M L Bruss, E M Huffman. Nonlinear pharmacokinetics and conversion to glucose of intravenous sodium propionate in dairy cattle.
Journal of dairy science.
1987 Nov; 70(11):2272-9. doi:
10.3168/jds.s0022-0302(87)80287-4
. [PMID: 3693632] - M L Bruss, Y Gröhn, E M Huffman, L A Lindberg. Hepatic morphology and effects of intravenous injection of sodium propionate on plasma propionate and glucose in fed and fasted dairy cattle.
American journal of veterinary research.
1986 Feb; 47(2):336-41. doi:
NULL
. [PMID: 3954216] - Y Gröhn. Propionate loading test for liver function in spontaneously ketotic dairy cows.
Research in veterinary science.
1985 Jul; 39(1):24-8. doi:
10.1016/s0034-5288(18)31764-8
. [PMID: 4035089] - Y Gröhn, M L Bruss, L A Lindberg. Propionate loading test for liver function during experimental liver necrosis in sheep.
American journal of veterinary research.
1985 Apr; 46(4):952-8. doi:
NULL
. [PMID: 4014846] - J P Peters, J M Elliot. Endocrine changes with infusion of propionate in the dairy cow.
Journal of dairy science.
1984 Oct; 67(10):2455-9. doi:
10.3168/jds.s0022-0302(84)81596-9
. [PMID: 6389631] - W J Chen, J W Anderson, D Jennings. Propionate may mediate the hypocholesterolemic effects of certain soluble plant fibers in cholesterol-fed rats.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1984 Feb; 175(2):215-8. doi:
10.3181/00379727-175-41791
. [PMID: 6320209] - T Yajima, K Kojima, K Tohyama, M Mutai. Alteration in sensitivity of transmural electrical response to propionate in rat colon after chronic luminal infusion of short-chain fatty acids.
Life sciences.
1983 Mar; 32(10):1073-9. doi:
10.1016/0024-3205(83)90112-1
. [PMID: 6827889]