Ciprofloxacin Hydrochloride (BioDeep_00000815433)
代谢物信息卡片
化学式: C17H21ClFN3O4 (385.12045480000006)
中文名称: 盐酸环丙沙星(一水物)
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O.O.Cl
InChI: 1H
描述信息
D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors > D065609 - Cytochrome P-450 CYP1A2 Inhibitors
D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones
C254 - Anti-Infective Agent > C52588 - Antibacterial Agent > C280 - Antitubercular Agent
C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic
Ciprofloxacin (Bay-09867) hydrochloride monohydrate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin hydrochloride monohydrate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin hydrochloride monohydrate has anti-proliferative activity and induces apoptosis. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity[1][2][3][4].
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:59936
- KEGGdrug: D02216
- KEGGdrug: D70790
- PubChem: 62998
- ChEMBL: CHEMBL4303345
- MeSH: Ciprofloxacin
- CAS: 128074-72-6
- CAS: 86393-32-0
- PubChem: 854234
- NIKKAJI: J245.528E
- KEGG: C13993
- medchemexpress: HY-B0356B
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Elif Yakamercan, Ahmet Aygün, Halis Simsek. Antibiotic ciprofloxacin removal from aqueous solutions by electrochemically activated persulfate process: Optimization, degradation pathways, and toxicology assessment.
Journal of environmental sciences (China).
2024 Sep; 143(?):85-98. doi:
10.1016/j.jes.2023.08.013
. [PMID: 38644026] - Pei Fan, Haihao Yu, Tian Lv, Huiyuan Wang, Dexiang Li, Chao Tong, Zhonghua Wu, Dan Yu, Chunhua Liu. Alien emergent aquatic plants develop better ciprofloxacin tolerance and metabolic capacity than one native submerged species.
The Science of the total environment.
2024 Jul; 932(?):173030. doi:
10.1016/j.scitotenv.2024.173030
. [PMID: 38719043] - Zuhier Alakayleh, Faisal Al-Akayleh, Mayyas Al-Remawi, Waseem Mahyoob, Husam A Abu Hajar, Muayad Esaifan, Reyad Shawabkeh. Utilizing olive leaves biomass as an efficient adsorbent for ciprofloxacin removal: characterization, isotherm, kinetic, and thermodynamic analysis.
Environmental monitoring and assessment.
2024 May; 196(6):562. doi:
10.1007/s10661-024-12712-0
. [PMID: 38769235] - Zirwa Fayyaz, Muhammad Akhyar Farrukh, Anwar Ul-Hamid, Kok-Keong Chong. Elucidating the structural, catalytic, and antibacterial traits of Ficus carica and Azadirachta indica leaf extract-mediated synthesis of the Ag/CuO/rGO nanocomposite.
Microscopy research and technique.
2024 May; 87(5):957-976. doi:
10.1002/jemt.24487
. [PMID: 38174385] - Giedrė Kacienė, Austra Dikšaitytė, Irena Januškaitienė, Diana Miškelytė, Gintarė Sujetovienė, Renata Dagiliūtė, Jūratė Žaltauskaitė. Veterinary antibiotics differ in phytotoxicity on oilseed rape grown over a wide range of concentrations.
Chemosphere.
2024 May; 356(?):141977. doi:
10.1016/j.chemosphere.2024.141977
. [PMID: 38608779] - Klaudia Stando, Michał Grzybowski, Anna Byczek-Wyrostek, Sylwia Bajkacz. Efficiency of phytoremediation and identification of biotransformation pathways of fluoroquinolones in the aquatic environment.
International journal of phytoremediation.
2024 May; 26(7):1027-1037. doi:
10.1080/15226514.2023.2288898
. [PMID: 38069676] - Junnan Li, Luhua You, Zichen Xu, Karina Yew-Hoong Gin, Yiliang He. Nano-scale and micron-scale plastics amplify the bioaccumulation of benzophenone-3 and ciprofloxacin, as well as their co-exposure effect on disturbing the antioxidant defense system in mussels, Perna viridis.
Environmental pollution (Barking, Essex : 1987).
2024 Apr; 346(?):123547. doi:
10.1016/j.envpol.2024.123547
. [PMID: 38387549] - M A Hossain, A U Ahmed, M M S Shahabuddin, K E Zannat, S M M Tanzim, A Afrin, S Nahar, M Aktar, R N Shimu, S Sultana, M Afrin, S Jahan. Antibacterial Activities of Methanolic Seeds Extract of Black pepper (Piper nigrum L.) against Gram Positive Staphylococcus aureus & Gram-Negative Escherichia coli.
Mymensingh medical journal : MMJ.
2024 Apr; 33(2):350-355. doi:
"
. [PMID: 38557509] - Xiaolian Wu, Chenze Jin, Gengying Du, Jianan Wang, Jiayi Su, Rongxuan Li. Urea promoted soil microbial community and reduced the residual ciprofloxacin in soil and its uptake by Chinese flowering cabbage.
Environmental science and pollution research international.
2024 Apr; 31(20):30137-30148. doi:
10.1007/s11356-024-33213-0
. [PMID: 38602632] - Yu-Hong Huang, Yu-Jie Yang, Jie-Yu Li, Huixiong Lü, Hai-Ming Zhao, Lei Xiang, Hui Li, Ce-Hui Mo, Yan-Wen Li, Quan-Ying Cai, Qing X Li. Root-associated bacteria strengthen their community stability against disturbance of antibiotics on structure and functions.
Journal of hazardous materials.
2024 Mar; 465(?):133317. doi:
10.1016/j.jhazmat.2023.133317
. [PMID: 38218031] - P Sirajunnisa, S Sreelakshmi, G S Sailaja. Lawsonia inermis-organically modified chitosan intercalated bentonite clay: A multifunctional nanotheranostic system for controlled drug delivery, sensing and cellular imaging.
International journal of biological macromolecules.
2024 Mar; 262(Pt 2):130209. doi:
10.1016/j.ijbiomac.2024.130209
. [PMID: 38365155] - Hussan Ibne Shoukani, Sobia Nisa, Yamin Bibi, Muhammad Zia, Anila Sajjad, Afsheen Ishfaq, Hussain Ali. Ciprofloxacin loaded PEG coated ZnO nanoparticles with enhanced antibacterial and wound healing effects.
Scientific reports.
2024 02; 14(1):4689. doi:
10.1038/s41598-024-55306-z
. [PMID: 38409460] - Érika M L Sousa, Marta Otero, María V Gil, Paula Ferreira, Valdemar I Esteves, Vânia Calisto. Evaluation of different functionalization methodologies for improving the removal of three target antibiotics from wastewater by a brewery waste activated carbon.
The Science of the total environment.
2024 Feb; 912(?):169437. doi:
10.1016/j.scitotenv.2023.169437
. [PMID: 38128671] - Hai-Ming Zhao, He-Biao Huang, Zhen-Xuan Zhan, Yao-Yao Ye, Ji-Liang Cheng, Lei Xiang, Yan-Wen Li, Quan-Ying Cai, Yunchang Xie, Ce-Hui Mo. Insights into the molecular network underlying phytotoxicity and phytoaccumulation of ciprofloxacin.
The Science of the total environment.
2024 Feb; 912(?):169392. doi:
10.1016/j.scitotenv.2023.169392
. [PMID: 38104812] - Mahmood Yousefi, Mahdi Farzadkia, Amir Hossein Mahvi, Majid Kermani, Mitra Gholami, Ali Esrafili. Photocatalytic degradation of ciprofloxacin using a novel carbohydrate-based nanocomposite from aqueous solutions.
Chemosphere.
2024 Feb; 349(?):140972. doi:
10.1016/j.chemosphere.2023.140972
. [PMID: 38114023] - Mengnan Shen, Yi Hu, Ke Zhao, Zhi Qu, Chen Lyu, Binshuo Liu, Ming Li, Xiaodan Bu, Chenyang Li, Shuang Zhong, Jie Cheng. Effects of dissolved organic matter, pH and nutrient on ciprofloxacin bioaccumulation and toxicity in duckweed.
Aquatic toxicology (Amsterdam, Netherlands).
2024 Jan; 266(?):106775. doi:
10.1016/j.aquatox.2023.106775
. [PMID: 38043483] - Luu Quynh Huong, Thomas Chisnall, John D Rodgers, Shaun A Cawthraw, Roderick M Card. Prevalence, antibiotic resistance, and genomic characterisation of Campylobacter spp. in retail chicken in Hanoi, Vietnam.
Microbial genomics.
2024 Jan; 10(1):. doi:
10.1099/mgen.0.001190
. [PMID: 38294872] - Gisele Canan-Rochenbach, Marco A B Barreiros, André O S Lima, Pascale Bauda, Eric Sanches-Simões, Wendell Pimentel-Almeida, Rafael Ariente-Neto, Cleder A Somensi, Tito C M Almeida, Rogério Corrêa, Claudemir M Radetski. Characterization of bacterial resistance in treated hospital wastewater.
Environmental technology.
2024 Jan; 45(1):120-128. doi:
10.1080/09593330.2022.2100282
. [PMID: 35802062] - Chandra Kant Singh, Kushneet Kaur Sodhi, Dileep Kumar Singh. Understanding the bacterial community structure associated with the Eichhornia crassipes rootzone.
Molecular biology reports.
2023 Dec; 51(1):35. doi:
10.1007/s11033-023-08979-0
. [PMID: 38157124] - Marina Ika Irianti, Jean-Paul Vincken, Sarah van Dinteren, Ellen Ter Beest, Klaas Martinus Pos, Carla Araya-Cloutier. Prenylated isoflavonoids from Fabaceae against the NorA efflux pump in Staphylococcus aureus.
Scientific reports.
2023 12; 13(1):22548. doi:
10.1038/s41598-023-48992-8
. [PMID: 38110428] - Gamze Ersan, Alexsandro J Dos Santos, Marcos R V Lanza, François Perreault, Sergi Garcia-Segura. Enhancing the selective ciprofloxacin adsorption in urine matrices through the metal-doping of carbon sorbents.
Journal of environmental management.
2023 Dec; 348(?):119298. doi:
10.1016/j.jenvman.2023.119298
. [PMID: 37839202] - Yong Xiao, Jiahong He, Jibin An, Taiping Xie, Junjie Lin. Highly efficient activation of peroxymonosulfate by ZIF-67 anchored cotton derived for ciprofloxacin degradation.
Environmental research.
2023 Dec; 244(?):117863. doi:
10.1016/j.envres.2023.117863
. [PMID: 38070857] - Adeola Olowofolahan, Omowumi Fatunsin, Olufunso Olorunsogo. Modulatory effect of ciprofloxacin, a broad spectrum antibacterial drug, on mPT pore using rat model with estradiol benzoate-induced endometrial hyperplasia.
Naunyn-Schmiedeberg's archives of pharmacology.
2023 Nov; ?(?):. doi:
10.1007/s00210-023-02824-8
. [PMID: 37943297] - Iñaki Deza-Cruz, María J Vilar, Martina Velasova, Manal AbuOun, Muna F Anjum, Richard P Smith. Antimicrobial resistance of Escherichia coli in the UK: comparison of single vs. pooled samples from healthy pigs.
Letters in applied microbiology.
2023 Nov; ?(?):. doi:
10.1093/lambio/ovad123
. [PMID: 37942558] - Jian-Fang Yan, Lei Xiang, Bi-Ying Zhang, Can Tang, You-Qun Xie, Yan-Wen Li, Nai-Xian Feng, Bai-Lin Liu, Hui Li, Quan-Ying Cai, Qing X Li, Hai-Ming Zhao, Ce-Hui Mo. Mechanism and Association between Microbial Nitrogen Transformation in Rhizosphere and Accumulation of Ciprofloxacin in Choysum (Brassica parachinensis).
Environmental science & technology.
2023 10; 57(42):16053-16064. doi:
10.1021/acs.est.3c04709
. [PMID: 37824517] - Genilson Silva de Jesus, Danielle Silva Trentin, Thayná Fernandes Barros, Alda Maria Teixeira Ferreira, Bruna Castro de Barros, Patrícia de Oliveira Figueiredo, Fernanda Rodrigues Garcez, Érica Luiz Dos Santos, Ana Camila Micheletti, Nidia Cristiane Yoshida. Medicinal plant Miconia albicans synergizes with ampicillin and ciprofloxacin against multi-drug resistant Acinetobacter baumannii and Staphylococcus aureus.
BMC complementary medicine and therapies.
2023 Oct; 23(1):374. doi:
10.1186/s12906-023-04147-w
. [PMID: 37872494] - Tanongsak Sassa-Deepaeng, Wachira Yodthong, Nattakanwadee Khumpirapang, Songyot Anuchapreeda, Siriporn Okonogi. Effects of plant-based copper nanoparticles on the elimination of ciprofloxacin.
Drug discoveries & therapeutics.
2023 Oct; ?(?):. doi:
10.5582/ddt.2023.01057
. [PMID: 37839876] - Amr M Shehabeldine, Abdulaziz A Al-Askar, Hamada AbdElgawad, Fatouh A Hagras, Amr A Ramadan, Mohamed R Kamel, Mohamed A Ahmed, Kareem H Atia, Amr H Hashem. Wound Dressing Scaffold with High Anti-biofilm Performance Based on Ciprofloxacin-Loaded Chitosan-Hydrolyzed Starch Nanocomposite: In Vitro and In Vivo Study.
Applied biochemistry and biotechnology.
2023 Oct; 195(10):6421-6439. doi:
10.1007/s12010-023-04665-w
. [PMID: 37450215] - K E Zannat, S M Tanzim, A Afrin, N Akter, M S Mostaqim, J B Joynal, M Ferdausee, B C Saha, N H Nira. Antibacterial Effects of Methanol Henna (Lawsone inermis) Leaf Extracts against Two Food Borne Infection Causing Pathogens: Gram-Positive Staphylococcus aureus and Gram Negative Klebsiella pneumoniae.
Mymensingh medical journal : MMJ.
2023 Oct; 32(4):1009-1014. doi:
. [PMID: 37777894]
- Tennyson Mathai, Tathagata Pal, Nayan Prakash, Soumyo Mukherji. Portable biosensor for the detection of Enrofloxacin and Ciprofloxacin antibiotic residues in food, body fluids, environmental and wastewater samples.
Biosensors & bioelectronics.
2023 Oct; 237(?):115478. doi:
10.1016/j.bios.2023.115478
. [PMID: 37356410] - Florence Nantaba, John Wasswa, Henrik Kylin, Hindrik Bouwman, Wolf-Ulrich Palm, Klaus Kümmerer. Spatial trends and ecotoxic risk assessment of selected pharmaceuticals in sediments from Lake Victoria, Uganda, East Africa.
The Science of the total environment.
2023 Sep; 906(?):167348. doi:
10.1016/j.scitotenv.2023.167348
. [PMID: 37769731] - Muhammad Talha Usmani, Muhammad Harris Shoaib, Fahad Siddiqui, Farrukh Rafiq Ahmed, Rabia Ismail Yousuf, Muhammad Talha Saleem. Formulation development, in vivo bioequivalence and pediatric PBPK modeling studies of taste-masked ciprofloxacin chewable tablets.
Scientific reports.
2023 09; 13(1):16070. doi:
10.1038/s41598-023-43423-0
. [PMID: 37752265] - Wenjie Cai, Mingqi Lu, Weijun Dai. Novel antibiotic susceptibility of an RNA polymerase α-subunit mutant in Pseudomonas aeruginosa.
The Journal of antimicrobial chemotherapy.
2023 09; 78(9):2162-2169. doi:
10.1093/jac/dkad207
. [PMID: 37428003] - Xiaowei Wu, Xiaoli Zhao, Xia Wang, Rouzheng Chen, Peng Liu, Weigang Liang, Junyu Wang, Di Shi, Shixiang Gao. Bioaccessibility of polypropylene microfiber-associated tetracycline and ciprofloxacin in simulated human gastrointestinal fluids.
Environment international.
2023 09; 179(?):108193. doi:
10.1016/j.envint.2023.108193
. [PMID: 37703772] - R Ricky, S Shanthakumar. An investigation on removal of ciprofloxacin and norfloxacin by phycoremediation with an emphasis on acute toxicity and biochemical composition.
Scientific reports.
2023 08; 13(1):13911. doi:
10.1038/s41598-023-41144-y
. [PMID: 37626153] - Henny Kasmawati, Ruslin Ruslin, Arfan Arfan, Nurramadhani A Sida, Dimas Isnu Saputra, Eli Halimah, Resmi Mustarichie. Antibacterial Potency of an Active Compound from Sansevieria trifasciata Prain: An Integrated In Vitro and In Silico Study.
Molecules (Basel, Switzerland).
2023 Aug; 28(16):. doi:
10.3390/molecules28166096
. [PMID: 37630348] - Saumya Singh, Taru Verma, Balaram Khamari, Eswarappa Pradeep Bulagonda, Dipankar Nandi, Siva Umapathy. Antimicrobial Resistance Studies Using Raman Spectroscopy on Clinically Relevant Bacterial Strains.
Analytical chemistry.
2023 08; 95(30):11342-11351. doi:
10.1021/acs.analchem.3c01453
. [PMID: 37463121] - Jiuyan Chen, Qiang Zhang, Yuwei Zhu, Mengli Zhang, Yutong Zhu, Usman Farooq, Taotao Lu, Zhichong Qi, Weifeng Chen. Adsorption of fluoroquinolone antibiotics onto ferrihydrite under different anionic surfactants and solution pH.
Environmental science and pollution research international.
2023 Jul; 30(32):78229-78242. doi:
10.1007/s11356-023-28059-x
. [PMID: 37269523] - K E Zannat, S K Saha, S M Tanzim, A Afrin, B C Saha, J B Joynal, M Aktar, N H Nira, N Akhter, M A Hossain. Antibacterial Effects of Chloroform Henna (Lawsonia inermis) Leaf Extracts against Two Nosocomial Infection Causing Pathogens: Gram-positive Staphylococcus aureus and Gram-negative Klebsiella pneumoniae: A Comparative Study.
Mymensingh medical journal : MMJ.
2023 Jul; 32(3):620-626. doi:
. [PMID: 37391949]
- Dina Dashty Mudher, Heshu Sulaiman Rahman, Sadat Abdulla Aziz, Amanpreet Kaur, Tareq Zeyad Bahjat, Hisham Al-Obaidi. Synthesis and in vivo evaluation of three fluid spray dried hybrid ciprofloxacin microparticles in Sprague Dawley rats.
Pharmaceutical development and technology.
2023 Jul; 28(6):547-558. doi:
10.1080/10837450.2023.2216801
. [PMID: 37256734] - Lei Zhao, Zhenzhen Han, Mengying Zhou, Cong Lyu, Yu Li. Field measures of strengthen plant-microbial remediation of PAHs-FQs compound pollution.
Environmental science and pollution research international.
2023 May; ?(?):. doi:
10.1007/s11356-023-27618-6
. [PMID: 37202637] - Mamadou Niang, John F Reichard, Andrew Maier, Glenn Talaska, Jun Ying, Jorge Santo Domingo, Eunice Varughese, Laura Boczek, Emma Huff, Tiina Reponen. Ciprofloxacin and azithromycin resistant bacteria in a wastewater treatment plant.
Journal of occupational and environmental hygiene.
2023 Apr; ?(?):1-12. doi:
10.1080/15459624.2023.2205485
. [PMID: 37084403] - Bahar Ikizoglu, Fatma Ilter Turkdogan, Gurdal Kanat, Coskun Aydiner. Seasonal analysis of commonly prescribed antibiotics in Istanbul city.
Environmental monitoring and assessment.
2023 Apr; 195(5):566. doi:
10.1007/s10661-023-11203-y
. [PMID: 37058249] - K E Zannat, S M Tanzim, A Afrin, B C Saha, J B Joynal, T A Khanam, N H Nira. Antibacterial Effects of Methanolic Leaf Extracts of Henna (Lawsonia inermis) Against Two Most Common Pathogenic Organisms: Gram Positive Staphylococcus aureus and Gram-Negative Escherichia coli.
Mymensingh medical journal : MMJ.
2023 Apr; 32(2):296-302. doi:
. [PMID: 37002737]
- Roxana Jijie, Emanuela Paduraru, Ira-Adeline Simionov, Caterina Faggio, Alin Ciobica, Mircea Nicoara. Effects of Single and Combined Ciprofloxacin and Lead Treatments on Zebrafish Behavior, Oxidative Stress, and Elements Content.
International journal of molecular sciences.
2023 Mar; 24(5):. doi:
10.3390/ijms24054952
. [PMID: 36902383] - Abraham Gana Yisa, Mathias Ahii Chia, Ibrahim Madu Katsallah Gadzama, Sonnie Joshua Oniye, Ramatu Idris Sha'aba, Balli Gauje. Immobilization, oxidative stress and antioxidant response of Daphnia magna to Amoxicillin and Ciprofloxacin.
Environmental toxicology and pharmacology.
2023 Mar; 98(?):104078. doi:
10.1016/j.etap.2023.104078
. [PMID: 36740085] - Ana Margarida Araújo, Henri Ringeard, Bruno Nunes. Do microplastics influence the long-term effects of ciprofloxacin on the polychaete Hediste diversicolor? An integrated behavioral and biochemical approach.
Environmental toxicology and pharmacology.
2023 Feb; ?(?):104088. doi:
10.1016/j.etap.2023.104088
. [PMID: 36841270] - Xuan Fu, Shovra Sarker, Weijia Ma, Weijie Zhao, Yan Rong, Qi Liu. Novel phenylalanine-modified magnetic ferroferric oxide nanoparticles for ciprofloxacin removal from aqueous solution.
Journal of colloid and interface science.
2023 Feb; 632(Pt B):345-356. doi:
10.1016/j.jcis.2022.11.067
. [PMID: 36436393] - Yuan-Yuan Wang, Xiao-Yi Zhang, Xiao-Lin Zhong, Yong-Jun Huang, Jing Lin, Wei-Min Chen. Design and Synthesis of 3-Hydroxy-pyridin-4(1H)-ones-Ciprofloxacin Conjugates as Dual Antibacterial and Antibiofilm Agents against Pseudomonas aeruginosa.
Journal of medicinal chemistry.
2023 02; 66(3):2169-2193. doi:
10.1021/acs.jmedchem.2c02044
. [PMID: 36692083] - Nazish Mohy-U-Din, Muhammad Farhan, Abdul Wahid, Lena Ciric, Faiza Sharif. Human health risk estimation of antibiotics transferred from wastewater and soil to crops.
Environmental science and pollution research international.
2023 Feb; 30(8):20601-20614. doi:
10.1007/s11356-022-23412-y
. [PMID: 36255570] - Hui Zhang, Huiyun Zou, Ling Zhao, Xuewen Li. Seasonal distribution and dynamic evolution of antibiotics and evaluation of their resistance selection potential and ecotoxicological risk at a wastewater treatment plant in Jinan, China.
Environmental science and pollution research international.
2023 Jan; ?(?):. doi:
10.1007/s11356-023-25202-6
. [PMID: 36690854] - Zhang Ruijuan, Xiao Li, Wang Yingjie, Wang Rui, Lu Chunqing. Effects of Catheter Tracking Management on Urinary Tract Function and Infection Rates in Patients With Spinal Cord Injury.
Alternative therapies in health and medicine.
2023 Jan; ?(?):. doi:
. [PMID: 36634314]
- K E Zannat, A U Ahmed, S M Tanzim, S M Ahmed, A Afrin, B C Saha, J B Joynal. Antibacterial Effects of Henna (Lawsonia inermis) Leaf Extracts (Chloroform) Against Two Food Borne and Nosocomial Infection Causing Pathogens: Staphylococcus aureus and Escherichia coli.
Mymensingh medical journal : MMJ.
2023 Jan; 32(1):83-89. doi:
"
. [PMID: 36594306] - Dhama Al-Sallami, Amjed Alsultan, Kadhim Hassan Abbas, Simon R Clarke. Evaluation of efflux pump inhibitory activity of some plant extracts and using them as adjuvants to potentiate the inhibitory activity of some antibiotics against Staphylococcus aureus.
Open veterinary journal.
2023 01; 13(1):42-47. doi:
10.5455/ovj.2023.v13.i1.5
. [PMID: 36777436] - M R A Ferreira, L B Lima, E C F Santos, J C B Machado, W A V Silva, P M G Paiva, T H Napoleão, L A L Soares. Eugenia uniflora: a promising natural alternative against multidrug-resistant bacteria.
Brazilian journal of biology = Revista brasleira de biologia.
2023; 83(?):e274084. doi:
10.1590/1519-6984.274084
. [PMID: 37585932] - Juntong Guo, Tianyi Wang, Zhifang Yan, Dongxu Ji, Jiayang Li, Hao Pan. Preparation and evaluation of dual drug-loaded nanofiber membranes based on coaxial electrostatic spinning technology.
International journal of pharmaceutics.
2022 Dec; 629(?):122410. doi:
10.1016/j.ijpharm.2022.122410
. [PMID: 36402289] - Sunidhi Bhatt, Subhankar Chatterjee. Fluoroquinolone antibiotics: Occurrence, mode of action, resistance, environmental detection, and remediation - A comprehensive review.
Environmental pollution (Barking, Essex : 1987).
2022 Dec; 315(?):120440. doi:
10.1016/j.envpol.2022.120440
. [PMID: 36265724] - Anna Barra Caracciolo, Andrea Visca, Jasmin Rauseo, Francesca Spataro, Gian Luigi Garbini, Paola Grenni, Livia Mariani, Valentina Mazzurco Miritana, Giulia Massini, Luisa Patrolecco. Bioaccumulation of antibiotics and resistance genes in lettuce following cattle manure and digestate fertilization and their effects on soil and phyllosphere microbial communities.
Environmental pollution (Barking, Essex : 1987).
2022 Dec; 315(?):120413. doi:
10.1016/j.envpol.2022.120413
. [PMID: 36243186] - Da-Yuan Wang, Guang Yang, Xiao-Xiao Zhang, Henny C van der Mei, Yijin Ren, Henk J Busscher, Linqi Shi. Proton-mediated burst of dual-drug loaded liposomes for biofilm dispersal and bacterial killing.
Journal of controlled release : official journal of the Controlled Release Society.
2022 12; 352(?):460-471. doi:
10.1016/j.jconrel.2022.10.049
. [PMID: 36341930] - Dan Deng, Zizi Mu, Xiaoyan Lv, Xincheng Jiang, Jiang Zhou, Huizhi Guo, Wenbing Zhang, Bei Wang, Yishan Lu, Jinping Wu, Hao Du, Shuhuan Zhang, Qiaoqing Xu, Qiwei Wei. Pathogenicity of Plesiomonas shigelloides and Citrobacter freundii isolated from the endangered Chinese sturgeon (Acipenser sinensis).
Microbial pathogenesis.
2022 Dec; 173(Pt A):105818. doi:
10.1016/j.micpath.2022.105818
. [PMID: 36216208] - Fatih Donmez, Abdulahad Dogan. Investigation of the effects of three different generations of fluoroquinolone derivatives on antioxidant and immunotoxic enzyme levels in different rat tissues.
Drug and chemical toxicology.
2022 Nov; 45(6):2686-2698. doi:
10.1080/01480545.2021.1982624
. [PMID: 34601990] - D H D Al Mnshad, A T Al Joudi, L Q Jawad, -Hasnawi R H M Al. Study the Ability of Salmonella typhimiurm to Induce Cytokine TNFα in Mice Treated with Olive Leaves Extract and Ciprofloxacin.
Archives of Razi Institute.
2022 10; 77(5):1799-1804. doi:
10.22092/ari.2022.358331.2196
. [PMID: 37123137] - M Swedha, Mohammad K Okla, Saud S Al-Amri, Ibrahim A Alaraidh, Abdullah A Al-Ghamdi, Asmaa Mohebaldin, Mostafa A Abdel-Maksoud, Mohammed Aufy, Christian R Studenik, Ajith M Thomas, Lija L Raju, S Sudheer Khan. Green synthesis of two-electron centre based ZnO/NiCo2S4 QDs-OVs using Punica granatum fruit peel extract for an exceptional visible light photocatalytic degradation of doxycycline and ciprofloxacin.
Chemosphere.
2022 Oct; 304(?):135225. doi:
10.1016/j.chemosphere.2022.135225
. [PMID: 35697102] - Surabhi Mangal, Sanjay Chhibber, Vasundhara Singh, Kusum Harjai. Guaiacol augments quorum quenching potential of ciprofloxacin against Pseudomonas aeruginosa.
Journal of applied microbiology.
2022 Oct; 133(4):2235-2254. doi:
10.1111/jam.15787
. [PMID: 35984044] - Joshua C Nwabuife, Calvin A Omolo, Thirumala Govender. Nano delivery systems to the rescue of ciprofloxacin against resistant bacteria "E. coli; P. aeruginosa; Saureus; and MRSA" and their infections.
Journal of controlled release : official journal of the Controlled Release Society.
2022 09; 349(?):338-353. doi:
10.1016/j.jconrel.2022.07.003
. [PMID: 35820538] - Jing Ma, Fu Chen, Yanfeng Zhu, Xiaoxiao Li, Haochen Yu, Yan Sun. Joint effects of microplastics and ciprofloxacin on their toxicity and fates in wheat: A hydroponic study.
Chemosphere.
2022 Sep; 303(Pt 2):135023. doi:
10.1016/j.chemosphere.2022.135023
. [PMID: 35605726] - Ronield Fernandez, Nieves R Colás-Ruiz, Gonzalo Martínez-Rodríguez, Pablo A Lara-Martín, Juan Miguel Mancera, Chiara Trombini, Julián Blasco, Miriam Hampel. The antibacterials ciprofloxacin, trimethoprim and sulfadiazine modulate gene expression, biomarkers and metabolites associated with stress and growth in gilthead sea bream (Sparus aurata).
Aquatic toxicology (Amsterdam, Netherlands).
2022 Sep; 250(?):106243. doi:
10.1016/j.aquatox.2022.106243
. [PMID: 35872527] - Junjun Feng, Haiyun Jiang, Jing Wang, Zhengyi Jing, Fan Zhang, Tianyu Tan, Feng He, Lihua Jiang, Haiqin Li, Shimin Chang, Tengfei Li. [Simultaneous determination of 40 plant growth regulators, fungicides, insecticides, and antibiotics in bean sprouts by QuEChERS-high performance liquid chromatography-tandem mass spectrometry].
Se pu = Chinese journal of chromatography.
2022 Sep; 40(9):843-853. doi:
10.3724/sp.j.1123.2021.12028
. [PMID: 36156631] - Ilanila Ilangumaran Ponmalar, Jitendriya Swain, Jaydeep K Basu. Modification of bacterial cell membrane dynamics and morphology upon exposure to sub inhibitory concentrations of ciprofloxacin.
Biochimica et biophysica acta. Biomembranes.
2022 08; 1864(8):183935. doi:
10.1016/j.bbamem.2022.183935
. [PMID: 35461827] - Jie Tang, Yun Wang, Qiang Xue, Fei Liu, Kenneth C Carroll, Xiaohua Lu, Taogeng Zhou, Dengjun Wang. A mechanistic study of ciprofloxacin adsorption by goethite in the presence of silver and titanium dioxide nanoparticles.
Journal of environmental sciences (China).
2022 Aug; 118(?):46-56. doi:
10.1016/j.jes.2021.08.052
. [PMID: 35305772] - Suzanne L de Vroom, Marcel C M Pistorius, Yuma A Bijleveld, Suzanne E Geerlings, Ron A A Mathôt, Reinier M van Hest, Nynke G L Jager. Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Assay for the Determination of Total and Unbound Ciprofloxacin Concentrations in Human Plasma.
Therapeutic drug monitoring.
2022 Aug; 44(4):552-557. doi:
10.1097/ftd.0000000000000969
. [PMID: 35094000] - Mohamed S El-Attar, Sadeek A Sadeek, Sherif M Abd El-Hamid, Hazem S Elshafie. Spectroscopic Analyses and Antimicrobial Activity of Novel Ciprofloxacin and 7-Hydroxy-4-methylcoumarin, the Plant-Based Natural Benzopyrone Derivative.
International journal of molecular sciences.
2022 Jul; 23(14):. doi:
10.3390/ijms23148019
. [PMID: 35887366] - I-Fan Lin, Chung-Hsu Lai, Shang-Yi Lin, Ching-Chi Lee, Nan-Yao Lee, Po-Yu Liu, Chih-Hui Yang, Yi-Han Huang, Jiun-Nong Lin. Mutant Prevention Concentrations of Ciprofloxacin and Levofloxacin and Target Gene Mutations of Fluoroquinolones in Elizabethkingia anophelis.
Antimicrobial agents and chemotherapy.
2022 07; 66(7):e0030122. doi:
10.1128/aac.00301-22
. [PMID: 35708332] - Xiang-Yu Wu, Jin-Bo Xiong, Chen-Jie Fei, Ting Dai, Ting-Fang Zhu, Zi-Yue Zhao, Jing Pan, Li Nie, Jiong Chen. Prior exposure to ciprofloxacin disrupts intestinal homeostasis and predisposes ayu ( Plecoglossus altivelis) to subsequent Pseudomonas plecoglossicida-induced infection.
Zoological research.
2022 Jul; 43(4):648-665. doi:
10.24272/j.issn.2095-8137.2022.159
. [PMID: 35838035] - Yu Hu, Qingqing Zhu, Yawei Wang, Chunyang Liao, Guibin Jiang. A short review of human exposure to antibiotics based on urinary biomonitoring.
The Science of the total environment.
2022 Jul; 830(?):154775. doi:
10.1016/j.scitotenv.2022.154775
. [PMID: 35339554] - Lucas Vinícius de Faria, Davi Marques de Farias, Thalles Pedrosa Lisboa, Maria Auxiliadora Costa Matos, Rodrigo Alejandro Abarza Munoz, Renato Camargo Matos. Batch injection analysis with amperometric detection for fluoroquinolone determination in urine, pharmaceutical formulations, and milk samples using a reduced graphene oxide-modified glassy carbon electrode.
Analytical and bioanalytical chemistry.
2022 Jul; 414(18):5309-5318. doi:
10.1007/s00216-021-03342-3
. [PMID: 33890118] - Farzaneh Salem, Ben G Small, Trevor N Johnson. Development and application of a pediatric mechanistic kidney model.
CPT: pharmacometrics & systems pharmacology.
2022 Jul; 11(7):854-866. doi:
10.1002/psp4.12798
. [PMID: 35506351] - Pei Fan, Chunhua Liu, Zhen Ke, Wei Zhou, Zhonghua Wu. Growth and physiological responses in a submerged clonal aquatic plant and multiple-endpoint assessment under prolonged exposure to ciprofloxacin.
Ecotoxicology and environmental safety.
2022 Jul; 239(?):113690. doi:
10.1016/j.ecoenv.2022.113690
. [PMID: 35643032] - Yang Deng, Xiyi Qian, Yiting Wu, Tian Ma, Xiaoguang Xu, Jiayi Li, Guoxiang Wang, Yan Yan. Effects of ciprofloxacin on Eichhornia crassipes phytoremediation performance and physiology under hydroponic conditions.
Environmental science and pollution research international.
2022 Jul; 29(31):47363-47372. doi:
10.1007/s11356-022-19008-1
. [PMID: 35179691] - Ky V Hoang, Katherine Woolard, Ching Yang, Christian Melander, John S Gunn. Identification of a Host-Targeted Compound to Control Typhoid Fever.
Microbiology spectrum.
2022 06; 10(3):e0061922. doi:
10.1128/spectrum.00619-22
. [PMID: 35579463] - Francesca Cappelli, Orietta Longoni, Jacopo Rigato, Michele Rusconi, Alberto Sala, Igor Fochi, Maria Teresa Palumbo, Stefano Polesello, Claudio Roscioli, Franco Salerno, Fabrizio Stefani, Roberta Bettinetti, Sara Valsecchi. Suspect screening of wastewaters to trace anti-COVID-19 drugs: Potential adverse effects on aquatic environment.
The Science of the total environment.
2022 Jun; 824(?):153756. doi:
10.1016/j.scitotenv.2022.153756
. [PMID: 35151733] - Moneeza Abbas, Shabnum Shaheen, Komal Idrees, Mehwish Jaffer, Rana Abrar Hussain, Muhammad Waheed Tabassum, Ghulam Rasool. Light microscopy and scanning electron microscopy: A helping tool to identify the adultrant of dye from Curcuma longa L rhizome, and its ecofriendly applications on pharmaceutical products.
Microscopy research and technique.
2022 Jun; 85(6):2277-2281. doi:
10.1002/jemt.24084
. [PMID: 35178821] - Oshadi Hettithanthri, Anushka Upamali Rajapaksha, S Keerthanan, Sammani Ramanayaka, Meththika Vithanage. Colloidal biochar for enhanced adsorption of antibiotic ciprofloxacin in aqueous and synthetic hydrolyzed human urine matrices.
Chemosphere.
2022 Jun; 297(?):133984. doi:
10.1016/j.chemosphere.2022.133984
. [PMID: 35202666] - Winnie Bao, Mira Koro, Gabriel W Loh, Ana Ortiz. Urinary Tract Infections in Long-term Care: Evaluation of Uropathogens, Antibiotic Susceptibility, and Empiric Treatment.
The Senior care pharmacist.
2022 Jun; 37(6):232-243. doi:
10.4140/tcp.n.2022.232
. [PMID: 35610764] - Izabella Kośka, Krystian Purgat, Paweł Kubalczyk. Simple, fast and reliable CE method for simultaneous determination of ciprofloxacin and ofloxacin in human urine.
Scientific reports.
2022 05; 12(1):7729. doi:
10.1038/s41598-022-11747-y
. [PMID: 35545693] - Fang Yang, Dan Liu, Chao Yang, Zhe-Wen Song, Hao-Tian Shao, Mei Zhang, Chao-Shuo Zhang, Zhen-Dong Zhang, Fan Yang. Development and application of a physiologically based pharmacokinetic model for orbifloxacin in crucian carp (Carassius auratus).
Journal of veterinary pharmacology and therapeutics.
2022 May; 45(3):311-319. doi:
10.1111/jvp.13049
. [PMID: 35243644] - Theodoros V Giannouchos, Ainhoa Gómez-Lumbreras, Daniel C Malone. Risk of tizanidine-induced adverse events after concomitant exposure to ciprofloxacin: A cohort study in the U.S.
The American journal of emergency medicine.
2022 05; 55(?):147-151. doi:
10.1016/j.ajem.2022.03.008
. [PMID: 35325788] - Zoe Oesterreicher, Sabine Eberl, Beatrix Wulkersdorfer, Peter Matzneller, Claudia Eder, Esther van Duijn, Wouter H J Vaes, Birgit Reiter, Thomas Stimpfl, Walter Jäger, Alina Nussbaumer-Proell, Daniela Marhofer, Peter Marhofer, Oliver Langer, Markus Zeitlinger. Microdosing as a Potential Tool to Enhance Clinical Development of Novel Antibiotics: A Tissue and Plasma PK Feasibility Study with Ciprofloxacin.
Clinical pharmacokinetics.
2022 05; 61(5):697-707. doi:
10.1007/s40262-021-01091-1
. [PMID: 34997559] - Katarzyna Pauter, Małgorzata Szultka-Młyńska, Michał Szumski, Anna Król-Górniak, Paweł Pomastowski, Bogusław Buszewski. CE-DAD-MS/MS in the simultaneous determination and identification of selected antibiotic drugs and their metabolites in human urine samples.
Electrophoresis.
2022 May; 43(9-10):978-989. doi:
10.1002/elps.202100190
. [PMID: 34624141] - Rafael Shinji Akiyama Kitamura, Maiara Vicentini, Maiara Carolina Perussolo, Juliana Roratto Lirola, Camilla Freitas Cirilo Dos Santos, Júlio César Moreira Brito, Marta Margarete Cestari, Maritana Mela Prodocimo, Marcelo Pedrosa Gomes, Helena Cristina Silva de Assis. Sublethal biochemical, histopathological and genotoxicological effects of short-term exposure to ciprofloxacin in catfish Rhamdia quelen.
Environmental pollution (Barking, Essex : 1987).
2022 May; 300(?):118935. doi:
10.1016/j.envpol.2022.118935
. [PMID: 35131333] - D Matmour, N Achachi, H Toumi. Quality of Active Pharmaceutical Ingredients Present on Algerian Soil: Control of Impurities of Ciprofloxacin, Metronidazole and Fluconazole.
Annales pharmaceutiques francaises.
2022 May; 80(3):261-272. doi:
10.1016/j.pharma.2021.10.002
. [PMID: 34687670] - Mengsuo Cui, Nan Hu, Dongyang Fang, Haowei Sun, Hao Pan, Weisan Pan. Fabrication and evaluation of customized implantable drug delivery system for orthopedic therapy based on 3D printing technologies.
International journal of pharmaceutics.
2022 Apr; 618(?):121679. doi:
10.1016/j.ijpharm.2022.121679
. [PMID: 35314275] - Apurva Pandey, Minhua Cao, Eszter Boros. Tracking Uptake and Metabolism of Xenometallomycins Using a Multi-Isotope Tagging Strategy.
ACS infectious diseases.
2022 04; 8(4):878-888. doi:
10.1021/acsinfecdis.2c00005
. [PMID: 35319188] - George G Zhanel, Marianna Pozdirca, Alyssa R Golden, Courtney K Lawrence, Sheryl Zelenitsky, Liam Berry, Frank Schweizer, Denice Bay, Heather Adam, Michael A Zhanel, Philippe Lagacé-Wiens, Andrew Walkty, Neal Irfan, Kurt Naber, Joseph P Lynch, James A Karlowsky. Sulopenem: An Intravenous and Oral Penem for the Treatment of Urinary Tract Infections Due to Multidrug-Resistant Bacteria.
Drugs.
2022 Apr; 82(5):533-557. doi:
10.1007/s40265-022-01688-1
. [PMID: 35294769] - M Mohammed Atiyah, H Shnawa Jasim, H Mohammed Atiyah. Phytochemical Screening and Antibacterial Activities of Aqueous and Alcoholic Extracts of Averrhoa bilimbi Leaf against Bacteria Isolated from Oral Cavity.
Archives of Razi Institute.
2022 Apr; 77(2):923-928. doi:
10.22092/ari.2022.357207.1996
. [PMID: 36284968] - Tetsuro Kuramae, Shingo Ishikawa, Aki Kono, Seiji Hobo. Pharmacokinetics in plasma and alveolar regions of a healthy calf intramuscularly administered a single dose of orbifloxacin.
The Journal of veterinary medical science.
2022 Mar; 84(3):400-405. doi:
10.1292/jvms.21-0517
. [PMID: 35095059] - Alexsandro J Dos Santos, Guilherme V Fortunato, Matheus S Kronka, Laís G Vernasqui, Neidenêi G Ferreira, Marcos R V Lanza. Electrochemical oxidation of ciprofloxacin in different aqueous matrices using synthesized boron-doped micro and nano-diamond anodes.
Environmental research.
2022 03; 204(Pt A):112027. doi:
10.1016/j.envres.2021.112027
. [PMID: 34508772] - Carla F Sousa, João T S Coimbra, Robert Richter, João H Morais-Cabral, Maria J Ramos, Claus-Michael Lehr, Pedro A Fernandes, Paula Gameiro. Exploring the permeation of fluoroquinolone metalloantibiotics across outer membrane porins by combining molecular dynamics simulations and a porin-mimetic in vitro model.
Biochimica et biophysica acta. Biomembranes.
2022 03; 1864(3):183838. doi:
10.1016/j.bbamem.2021.183838
. [PMID: 34896074] - Kiyoko Fujita, Iichiro Takata, Ippei Yoshida, Hajime Takashima, Hiroyuki Sugiyama. TP0586532, a non-hydroxamate LpxC inhibitor, reduces LPS release and IL-6 production both in vitro and in vivo.
The Journal of antibiotics.
2022 03; 75(3):136-145. doi:
10.1038/s41429-021-00498-z
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