diglycidyl ether (BioDeep_00000815322)
代谢物信息卡片
diglycidyl ether
化学式: C6H10O3 (130.063)
中文名称: 二缩水甘油醚
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(O1)COCC2CO2
InChI: InChI=1S/C6H10O3/c1(5-3-8-5)7-2-6-4-9-6/h5-6H,1-4H2
相关代谢途径
Reactome(0)
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PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Nadav Ben-Dov, Rafi Korenstein. Enhancement of cell membrane invaginations, vesiculation and uptake of macromolecules by protonation of the cell surface.
PloS one.
2012; 7(4):e35204. doi:
10.1371/journal.pone.0035204. [PMID: 22558127] - Frederique K H Breuers, Andrea Bräutigam, Stefan Geimer, Ulla Y Welzel, Giovanni Stefano, Luciana Renna, Federica Brandizzi, Andreas P M Weber. Dynamic Remodeling of the Plastid Envelope Membranes - A Tool for Chloroplast Envelope in vivo Localizations.
Frontiers in plant science.
2012; 3(?):7. doi:
10.3389/fpls.2012.00007. [PMID: 22645566] - Tamotsu Tsukahara. The Role of PPARγ in the Transcriptional Control by Agonists and Antagonists.
PPAR research.
2012; 2012(?):362361. doi:
10.1155/2012/362361. [PMID: 22693486] - Fabrice Marquet, Jean-Paul Payan, Dominique Beydon, Ludivine Wathier, Marie-Christine Grandclaude, Elisabeth Ferrari. In vivo and ex vivo percutaneous absorption of [14C]-bisphenol A in rats: a possible extrapolation to human absorption?.
Archives of toxicology.
2011 Sep; 85(9):1035-43. doi:
10.1007/s00204-011-0651-z. [PMID: 21287149] - Eva Morán-Salvador, Marta López-Parra, Verónica García-Alonso, Esther Titos, Marcos Martínez-Clemente, Ana González-Périz, Cristina López-Vicario, Yaacov Barak, Vicente Arroyo, Joan Clària. Role for PPARγ in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2011 Aug; 25(8):2538-50. doi:
10.1096/fj.10-173716. [PMID: 21507897] - K Celinski, T Dworzanski, A Korolczuk, R Piasecki, M Slomka, A Madro, R Fornal. Effects of peroxisome proliferator-activated receptors-gamma ligands on dextran sodium sulphate-induced colitis in rats.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2011 Jun; 62(3):347-56. doi:
. [PMID: 21893696] - Krzysztof Celinski, Tomasz Dworzanski, Agnieszka Korolczuk, Maria Slomka, Sebastian Radej, Halina Cichoz-Lach, Agnieszka Madro. Activated and inactivated PPARs-γ modulate experimentally induced colitis in rats.
Medical science monitor : international medical journal of experimental and clinical research.
2011 Apr; 17(4):BR116-24. doi:
10.12659/msm.881712. [PMID: 21455100] - Li You, Xiangzhu Zhu, Martha J Shrubsole, Hong Fan, Jing Chen, Jie Dong, Chuan-Ming Hao, Qi Dai. Renal function, bisphenol A, and alkylphenols: results from the National Health and Nutrition Examination Survey (NHANES 2003-2006).
Environmental health perspectives.
2011 Apr; 119(4):527-33. doi:
10.1289/ehp.1002572. [PMID: 21147601] - Daeyoung Kim, Kwang-Kyun Park, Sang Kook Lee, Seung-Eun Lee, Jae-Kwan Hwang. Cornus kousa F.Buerger ex Miquel increases glucose uptake through activation of peroxisome proliferator-activated receptor γ and insulin sensitization.
Journal of ethnopharmacology.
2011 Jan; 133(2):803-9. doi:
10.1016/j.jep.2010.11.007. [PMID: 21070843] - Tamara Galloway, Riccardo Cipelli, Jack Guralnik, Luigi Ferrucci, Stefania Bandinelli, Anna Maria Corsi, Cathryn Money, Paul McCormack, David Melzer. Daily bisphenol A excretion and associations with sex hormone concentrations: results from the InCHIANTI adult population study.
Environmental health perspectives.
2010 Nov; 118(11):1603-8. doi:
10.1289/ehp.1002367. [PMID: 20797929] - Katsutaka Oishi, Daisuke Uchida, Naoki Ohkura, Shuichi Horie. PPARα deficiency augments a ketogenic diet-induced circadian PAI-1 expression possibly through PPARγ activation in the liver.
Biochemical and biophysical research communications.
2010 Oct; 401(2):313-8. doi:
10.1016/j.bbrc.2010.09.060. [PMID: 20854792] - Jaime Mendiola, Niels Jørgensen, Anna-Maria Andersson, Antonia M Calafat, Xiaoyun Ye, J Bruce Redmon, Erma Z Drobnis, Christina Wang, Amy Sparks, Sally W Thurston, Fan Liu, Shanna H Swan. Are environmental levels of bisphenol a associated with reproductive function in fertile men?.
Environmental health perspectives.
2010 Sep; 118(9):1286-91. doi:
10.1289/ehp.1002037. [PMID: 20494855] - Harikesh Kalonia, Puneet Kumar, Anil Kumar. Pioglitazone ameliorates behavioral, biochemical and cellular alterations in quinolinic acid induced neurotoxicity: possible role of peroxisome proliferator activated receptor-Upsilon (PPARUpsilon) in Huntington's disease.
Pharmacology, biochemistry, and behavior.
2010 Aug; 96(2):115-24. doi:
10.1016/j.pbb.2010.04.018. [PMID: 20450929] - Laura N Vandenberg, Ibrahim Chahoud, Jerrold J Heindel, Vasantha Padmanabhan, Francisco J R Paumgartten, Gilbert Schoenfelder. Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A.
Environmental health perspectives.
2010 Aug; 118(8):1055-70. doi:
10.1289/ehp.0901716. [PMID: 20338858] - Chang Yeop Han, Atil Y Kargi, Mohamed Omer, Christina K Chan, Martin Wabitsch, Kevin D O'Brien, Thomas N Wight, Alan Chait. Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation.
Diabetes.
2010 Feb; 59(2):386-96. doi:
10.2337/db09-0925. [PMID: 19934003] - David Melzer, Neil E Rice, Ceri Lewis, William E Henley, Tamara S Galloway. Association of urinary bisphenol a concentration with heart disease: evidence from NHANES 2003/06.
PloS one.
2010 Jan; 5(1):e8673. doi:
10.1371/journal.pone.0008673. [PMID: 20084273] - Yuhong Yang, Amy E Lovett-Racke, Michael K Racke. Regulation of Immune Responses and Autoimmune Encephalomyelitis by PPARs.
PPAR research.
2010; 2010(?):104705. doi:
10.1155/2010/104705. [PMID: 21234105] - Yulan Liu, Junxia Shi, Jing Lu, Guoquan Meng, Huiling Zhu, Yongqing Hou, Yulong Yin, Shengjun Zhao, Binying Ding. Activation of peroxisome proliferator-activated receptor-gamma potentiates pro-inflammatory cytokine production, and adrenal and somatotropic changes of weaned pigs after Escherichia coli lipopolysaccharide challenge.
Innate immunity.
2009 Jun; 15(3):169-78. doi:
10.1177/1753425908102014. [PMID: 19474210] - Yu-Lun Lou, Yu-Shiang Peng, Bing-Hung Chen, Li-Fang Wang, Kam W Leong. Poly(ethylene imine)-g-chitosan using EX-810 as a spacer for nonviral gene delivery vectors.
Journal of biomedical materials research. Part A.
2009 Mar; 88(4):1058-68. doi:
10.1002/jbm.a.31961. [PMID: 18404706] - L-F Liu, A Purushotham, A A Wendel, K Koba, J DeIuliis, K Lee, M A Belury. Regulation of adipose triglyceride lipase by rosiglitazone.
Diabetes, obesity & metabolism.
2009 Feb; 11(2):131-42. doi:
10.1111/j.1463-1326.2008.00916.x. [PMID: 18643838] - Nicolas Cabaton, Coralie Dumont, Isabelle Severin, Elisabeth Perdu, Daniel Zalko, Mustapha Cherkaoui-Malki, Marie-Christine Chagnon. Genotoxic and endocrine activities of bis(hydroxyphenyl)methane (bisphenol F) and its derivatives in the HepG2 cell line.
Toxicology.
2009 Jan; 255(1-2):15-24. doi:
10.1016/j.tox.2008.09.024. [PMID: 18973785] - Rolando Barbucci, Daniela Pasqui, Roberto Favaloro, Giuseppe Panariello. A thixotropic hydrogel from chemically cross-linked guar gum: synthesis, characterization and rheological behaviour.
Carbohydrate research.
2008 Dec; 343(18):3058-65. doi:
10.1016/j.carres.2008.08.029. [PMID: 18822410] - Jun-Won Yun, Eui-Seok Shin, Si-Young Cho, Shin-Hyoung Kim, Chae-Wook Kim, Tae-Ryong Lee, Bae-Hwan Kim. The effects of BADGE and caffeine on the time-course response of adiponectin and lipid oxidative enzymes in high fat diet-fed C57BL/6J mice: correlation with reduced adiposity and steatosis.
Experimental animals.
2008 Oct; 57(5):461-9. doi:
10.1538/expanim.57.461. [PMID: 18946183] - Hironori Yamazoe, Toshimasa Uemura, Toshizumi Tanabe. Facile cell patterning on an albumin-coated surface.
Langmuir : the ACS journal of surfaces and colloids.
2008 Aug; 24(16):8402-4. doi:
10.1021/la801221r. [PMID: 18627191] - Hironori Yamazoe, Toshizumi Tanabe. Preparation of water-insoluble albumin film possessing nonadherent surface for cells and ligand binding ability.
Journal of biomedical materials research. Part A.
2008 Jul; 86(1):228-34. doi:
10.1002/jbm.a.31654. [PMID: 17975816] - Kazuto Takahashi, Shinya Yamaguchi, Tatsuhiro Shimoyama, Hiroyuki Seki, Kaoru Miyokawa, Hidenori Katsuta, Toshiaki Tanaka, Katsuhiko Yoshimoto, Hideki Ohno, Shinya Nagamatsu, Hitoshi Ishida. JNK- and IkappaB-dependent pathways regulate MCP-1 but not adiponectin release from artificially hypertrophied 3T3-L1 adipocytes preloaded with palmitate in vitro.
American journal of physiology. Endocrinology and metabolism.
2008 May; 294(5):E898-909. doi:
10.1152/ajpendo.00131.2007. [PMID: 18303122] - Min-Chul Cho, Kyoung Lee, Sang-Gi Paik, Do-Young Yoon. Peroxisome Proliferators-Activated Receptor (PPAR) Modulators and Metabolic Disorders.
PPAR research.
2008; 2008(?):679137. doi:
10.1155/2008/679137. [PMID: 18566691] - Heath A Elrod, Shi-Yong Sun. PPARgamma and Apoptosis in Cancer.
PPAR research.
2008; 2008(?):704165. doi:
10.1155/2008/704165. [PMID: 18615184] - Un-jun Hyoung, Yun-jung Yang, Su-kyoung Kwon, Jae-hyoung Yoo, Soon-chul Myoung, Sae-chul Kim, Yeon-pyo Hong. Developmental toxicity by exposure to bisphenol A diglycidyl ether during gestation and lactation period in Sprague-Dawley male rats.
Journal of preventive medicine and public health = Yebang Uihakhoe chi.
2007 Mar; 40(2):155-61. doi:
10.3961/jpmph.2007.40.2.155. [PMID: 17426428] - Ze-Jian Wang, Cui-Ling Liang, Guang-Mei Li, Cai-Yi Yu, Ming Yin. Stearic acid protects primary cultured cortical neurons against oxidative stress.
Acta pharmacologica Sinica.
2007 Mar; 28(3):315-26. doi:
10.1111/j.1745-7254.2007.00512.x. [PMID: 17302992] - Shiu-Chih Wang, Bing-Hung Chen, Li-Fang Wang, Jenn-Shing Chen. Characterization of chondroitin sulfate and its interpenetrating polymer network hydrogels for sustained-drug release.
International journal of pharmaceutics.
2007 Feb; 329(1-2):103-9. doi:
10.1016/j.ijpharm.2006.08.041. [PMID: 16996709] - Rosanna Di Paola, Salvatore Cuzzocrea. Peroxisome proliferator-activated receptors and acute lung injury.
PPAR research.
2007; 2007(?):63745. doi:
10.1155/2007/63745. [PMID: 17710233] - Jane Elizabeth Ward, Xiahui Tan. Peroxisome proliferator activated receptor ligands as regulators of airway inflammation and remodelling in chronic lung disease.
PPAR research.
2007; 2007(?):14983. doi:
10.1155/2007/14983. [PMID: 18000530] - Graciela Ramilo, Iago Valverde, Jorge Lago, Juan M Vieites, Ana G Cabado. Cytotoxic effects of BADGE (bisphenol A diglycidyl ether) and BFDGE (bisphenol F diglycidyl ether) on Caco-2 cells in vitro.
Archives of toxicology.
2006 Nov; 80(11):748-55. doi:
10.1007/s00204-006-0121-1. [PMID: 16783546] - Ariela Benigni, Carla Zoja, Susanna Tomasoni, Marco Campana, Daniela Corna, Cristina Zanchi, Elena Gagliardini, Elvira Garofano, Daniela Rottoli, Takahito Ito, Giuseppe Remuzzi. Transcriptional regulation of nephrin gene by peroxisome proliferator-activated receptor-gamma agonist: molecular mechanism of the antiproteinuric effect of pioglitazone.
Journal of the American Society of Nephrology : JASN.
2006 Jun; 17(6):1624-32. doi:
10.1681/asn.2005090983. [PMID: 16687628] - Katherine E Liney, Josephine A Hagger, Charles R Tyler, Michael H Depledge, Tamara S Galloway, Susan Jobling. Health effects in fish of long-term exposure to effluents from wastewater treatment works.
Environmental health perspectives.
2006 Apr; 114 Suppl 1(?):81-9. doi:
10.1289/ehp.8058. [PMID: 16818251] - Tadaatsu Imaizumi, Koji Yamashita, Kageaki Taima, Akira Ishikawa, Hidemi Yoshida, Kei Satoh. Effect of peroxisome proliferator-activated receptor-gamma ligands on the expression of retinoic acid-inducible gene-I in endothelial cells stimulated with lipopolysaccharide.
Prostaglandins & other lipid mediators.
2005 Dec; 78(1-4):46-54. doi:
10.1016/j.prostaglandins.2005.02.006. [PMID: 16303604] - Shinichiro Sakata, Jennifer Cahill, David Barton, Rosemary Nixon. Occupational allergic contact dermatitis to bisphenol F epoxy resin.
The Australasian journal of dermatology.
2005 May; 46(2):90-2. doi:
10.1111/j.1440-0960.2005.00149.x. [PMID: 15842401] - Antonia M Calafat, Zsuzsanna Kuklenyik, John A Reidy, Samuel P Caudill, John Ekong, Larry L Needham. Urinary concentrations of bisphenol A and 4-nonylphenol in a human reference population.
Environmental health perspectives.
2005 Apr; 113(4):391-5. doi:
10.1289/ehp.7534. [PMID: 15811827] - Hang Li, Xiong Z Ruan, Stephen H Powis, Ray Fernando, Wint Y Mon, David C Wheeler, John F Moorhead, Zac Varghese. EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: evidence for a PPAR-gamma-dependent mechanism.
Kidney international.
2005 Mar; 67(3):867-74. doi:
10.1111/j.1523-1755.2005.00151.x. [PMID: 15698426] - Michael A Lea, Monali Sura, Charles Desbordes. Inhibition of cell proliferation by potential peroxisome proliferator-activated receptor (PPAR) gamma agonists and antagonists.
Anticancer research.
2004 Sep; 24(5A):2765-71. doi:
". [PMID: 15517883] - Salvatore Cuzzocrea, Barbara Pisano, Laura Dugo, Angela Ianaro, Pasquale Maffia, Nimesh S A Patel, Rosanna Di Paola, Armando Ialenti, Tiziana Genovese, Prabal K Chatterjee, Massimo Di Rosa, Achille P Caputi, Christoph Thiemermann. Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation.
European journal of pharmacology.
2004 Jan; 483(1):79-93. doi:
10.1016/j.ejphar.2003.10.056. [PMID: 14709329] - Salvatore Cuzzocrea, Barbara Pisano, Laura Dugo, Angela Ianaro, Nimesh S A Patel, Rosanna Di Paola, Tiziana Genovese, Prabal K Chatterjee, Massimo Di Rosa, Achille P Caputi, Christoph Thiemermann. Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut.
British journal of pharmacology.
2003 Sep; 140(2):366-76. doi:
10.1038/sj.bjp.0705419. [PMID: 12970094] - T Hanaoka, N Kawamura, K Hara, S Tsugane. Urinary bisphenol A and plasma hormone concentrations in male workers exposed to bisphenol A diglycidyl ether and mixed organic solvents.
Occupational and environmental medicine.
2002 Sep; 59(9):625-8. doi:
10.1136/oem.59.9.625. [PMID: 12205237] - C Brede, I Skjevrak, H Herikstad, E Anensen, R Austvoll, T Hemmingsen. Improved sample extraction and clean-up for the GC-MS determination of BADGE and BFDGE in vegetable oil.
Food additives and contaminants.
2002 May; 19(5):483-91. doi:
10.1080/02652030110088293. [PMID: 12028648] - J E Sanders, A B Baker, S L Golledge. Control of in vivo microvessel ingrowth by modulation of biomaterial local architecture and chemistry.
Journal of biomedical materials research.
2002 Apr; 60(1):36-43. doi:
10.1002/jbm.1279. [PMID: 11835157] - Sebastian Fehlberg, Stefan Trautwein, Alexandra Göke, Rüdiger Göke. Bisphenol A diglycidyl ether induces apoptosis in tumour cells independently of peroxisome proliferator-activated receptor-gamma, in caspase-dependent and -independent manners.
The Biochemical journal.
2002 Mar; 362(Pt 3):573-8. doi:
10.1042/0264-6021:3620573. [PMID: 11879183] - Malene Jensen, Pernille Birch Hansen, Sudaxshina Murdan, Sven Frokjaer, Alexander T Florence. Loading into and electro-stimulated release of peptides and proteins from chondroitin 4-sulphate hydrogels.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2002 Mar; 15(2):139-48. doi:
10.1016/s0928-0987(01)00193-2. [PMID: 11849910] - Elida González, Alicia Jawerbaum, Débora Sinner, Carolina Pustovrh, Verónica White, Evangelina Capobianco, Carme Xaus, Carmen Peralta, Joan Roselló-Catafau. Streptozotocin-pancreatic damage in the rat: modulatory effect of 15-deoxy delta12,14-prostaglandin j(2) on nitridergic and prostanoid pathway.
Nitric oxide : biology and chemistry.
2002 Mar; 6(2):214-20. doi:
10.1006/niox.2001.0405. [PMID: 11890746] - Kozo Yokota, Yasushi Johyama, Naomi Matsumoto, Kyohei Yamaguchi. Occupational dermatitis from a one-component naphthalene type epoxy adhesive.
Industrial health.
2002 Jan; 40(1):63-5. doi:
10.2486/indhealth.40.63. [PMID: 11926518] - K Inoue, A Yamaguchi, M Wada, Y Yoshimura, T Makino, H Nakazaw. Quantitative detection of bisphenol A and bisphenol A diglycidyl ether metabolites in human plasma by liquid chromatography-electrospray mass spectrometry.
Journal of chromatography. B, Biomedical sciences and applications.
2001 Dec; 765(2):121-6. doi:
10.1016/s0378-4347(01)00393-0. [PMID: 11767304] - A Pontén, M Bruze. Contact allergy to epoxy resin based on diglycidyl ether of bisphenol F.
Contact dermatitis.
2001 Feb; 44(2):98-9. doi:
10.1034/j.1600-0536.2001.4402092.x. [PMID: 11205414] - U Berger, M Oehme, L Girardin. Quantification of derivatives of bisphenol A diglycidyl ether (BADGE) and novolac glycidyl ether (NOGE) migrated from can coatings into tuna by HPLC/fluorescence and MS detection.
Fresenius' journal of analytical chemistry.
2001 Jan; 369(2):115-23. doi:
10.1007/s002160000668. [PMID: 11225353] - J Watkins, A Padfield, J D Alderson. Underlying immunopathology as a cause of adverse responses to two intravenous anaesthetic agents.
British medical journal.
1978 May; 1(6121):1180-1. doi:
10.1136/bmj.1.6121.1180. [PMID: 638678]
