ubiquinone-7 (BioDeep_00000812726)
代谢物信息卡片
化学式: C44H66O4 (658.4960836)
中文名称: 辅酶Q7
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C(=O)C(=C(C1=O)OC)OC)CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C
InChI: InChI=1S/C44H66O4/c1-32(2)18-12-19-33(3)20-13-21-34(4)22-14-23-35(5)24-15-25-36(6)26-16-27-37(7)28-17-29-38(8)30-31-40-39(9)41(45)43(47-10)44(48-11)42(40)46/h18,20,22,24,26,28,30H,12-17,19,21,23,25,27,29,31H2,1-11H3/b33-20+,34-22+,35-24+,36-26+,37-28+,38-30+
描述信息
A compound whose structure comprises a 2,3-dimethoxy-5-methylbenzoquinone nucleus, common to ubiquinones; and a side chain of seven isoprenoid units.
C26170 - Protective Agent > C275 - Antioxidant
同义名列表
2 个代谢物同义名
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:46448
- PubChem: 5289540
- CAS: 25222-34-8
- CAS: 303-95-7
- MetaboLights: MTBLC46448
- LOTUS: LTS0164389
- wikidata: Q27120651
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
2 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(2)
- TCA cycle (ubiquinol-7):
Citric acid ⟶ Water + cis-Aconitic acid - TCA Cycle (Ubiquinol-7):
Water + cis-Aconitic acid ⟶ D-threo-Isocitric acid
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Adriana P Rebelo, Pedro J Tomaselli, Jessica Medina, Ying Wang, Maike Dohrn, Eva Nyvltova, Matt Denzi, Mark Garrett, Sean Smith, Alan Pestronk, ChengCheng Li, Ariel Ruiz, Elizabeth Jacobs, Shawna M E Feely, Marcondes C França, Marcus V Gomes, Diogo Santos, Surinder Kumar, David B Lombard, Mario Saporta, Siegfried Hekimi, Antonio Barrientos, Conrad Weihl, Michael Shy, Wilson Marques, Stephan Zuchner. Biallelic variants in COQ7 cause distal hereditary motor neuropathy with upper motor neuron signs.
Brain : a journal of neurology.
2023 May; ?(?):. doi:
10.1093/brain/awad158. [PMID: 37170631] - Mateusz Manicki, Halil Aydin, Luciano A Abriata, Katherine A Overmyer, Rachel M Guerra, Joshua J Coon, Matteo Dal Peraro, Adam Frost, David J Pagliarini. Structure and functionality of a multimeric human COQ7:COQ9 complex.
Molecular cell.
2022 11; 82(22):4307-4323.e10. doi:
10.1016/j.molcel.2022.10.003. [PMID: 36306796] - Chao-Nan Wang, Feng-Qing Wang, Yuan Liu, Ming-Yi Wang, Zong-Jun Du. Ostreibacterium oceani gen. nov., sp. nov., isolated from oyster, and description of Ostreibacteriaceae fam. nov.
International journal of systematic and evolutionary microbiology.
2021 Jul; 71(7):. doi:
10.1099/ijsem.0.004855. [PMID: 34228610] - Line Christiansen, Pernille Kjersgaard Bech, Mikkel Schultz-Johansen, Helle Juel Martens, Peter Stougaard. Colwellia echini sp. nov., an agar- and carrageenan-solubilizing bacterium isolated from sea urchin.
International journal of systematic and evolutionary microbiology.
2018 Feb; 68(2):687-691. doi:
10.1099/ijsem.0.002568. [PMID: 29388544] - Yan Wang, Hongli Chen, Zhenhua Liu, Hong Ming, Chenyan Zhou, Xinshu Zhu, Peng Zhang, Changqin Jing, Huigen Feng. Shewanella gelidii sp. nov., isolated from the red algae Gelidium amansii, and emended description of Shewanella waksmanii.
International journal of systematic and evolutionary microbiology.
2016 Aug; 66(8):2899-2905. doi:
10.1099/ijsem.0.001075. [PMID: 27064664] - Cristina Parrado-Fernández, Guillermo López-Lluch, Elisabet Rodríguez-Bies, Sara Santa-Cruz, Plácido Navas, Jon J Ramsey, José M Villalba. Calorie restriction modifies ubiquinone and COQ transcript levels in mouse tissues.
Free radical biology & medicine.
2011 Jun; 50(12):1728-36. doi:
10.1016/j.freeradbiomed.2011.03.024. [PMID: 21447381] - S Padilla, U C Tran, M Jiménez-Hidalgo, J M López-Martín, A Martín-Montalvo, C F Clarke, P Navas, C Santos-Ocaña. Hydroxylation of demethoxy-Q6 constitutes a control point in yeast coenzyme Q6 biosynthesis.
Cellular and molecular life sciences : CMLS.
2009 Jan; 66(1):173-86. doi:
10.1007/s00018-008-8547-7. [PMID: 19002377] - Julio Gallego-Delgado, Alberto Lazaro, Julio I Osende, Vanesa Esteban, Maria G Barderas, Carmen Gomez-Guerrero, Ricardo Vega, Fernando Vivanco, Jesus Egido. Proteomic analysis of early left ventricular hypertrophy secondary to hypertension: modulation by antihypertensive therapies.
Journal of the American Society of Nephrology : JASN.
2006 Dec; 17(12 Suppl 3):S159-64. doi:
10.1681/asn.2006080937. [PMID: 17130255] - D Nakai, S Yuasa, M Takahashi, T Shimizu, S Asaumi, K Isono, T Takao, Y Suzuki, H Kuroyanagi, K Hirokawa, H Koseki, T Shirsawa. Mouse homologue of coq7/clk-1, longevity gene in Caenorhabditis elegans, is essential for coenzyme Q synthesis, maintenance of mitochondrial integrity, and neurogenesis.
Biochemical and biophysical research communications.
2001 Nov; 289(2):463-71. doi:
10.1006/bbrc.2001.5977. [PMID: 11716496] - T Jonassen, M Proft, F Randez-Gil, J R Schultz, B N Marbois, K D Entian, C F Clarke. Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis.
The Journal of biological chemistry.
1998 Feb; 273(6):3351-7. doi:
10.1074/jbc.273.6.3351. [PMID: 9452453] - B N Marbois, C F Clarke. The COQ7 gene encodes a protein in saccharomyces cerevisiae necessary for ubiquinone biosynthesis.
The Journal of biological chemistry.
1996 Feb; 271(6):2995-3004. doi:
10.1074/jbc.271.6.2995. [PMID: 8621692]