Ramentaceone (BioDeep_00000008071)

PANOMIX_OTCML-2023 Volatile Flavor Compounds

代谢物信息卡片

1,4-Naphthalenedione,5-hydroxy-7-methyl-

化学式: C11H8O3 (188.0473418)
中文名称: 拉曼曲松
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 38.46%

分子结构信息

SMILES: c1(cc(c2c(c1)C(=O)C=CC2=O)O)C
InChI: InChI=1S/C11H8O3/c1-6-4-7-8(12)2-3-9(13)11(7)10(14)5-6/h2-5,14H,1H3

描述信息

同义名列表

4 个代谢物同义名

1,4-Naphthalenedione,5-hydroxy-7-methyl-; 7-Methyljuglone; Ramentaceone; Ramentaceone

数据库引用编号

14 个数据库交叉引用编号

ChEBI: CHEBI:8773
KEGG: C10398
PubChem: 26905
Metlin: METLIN68304
ChEMBL: CHEMBL430853
KNApSAcK: C00002859
CAS: 14787-38-3
PMhub: MS000021610
PubChem: 12584
3DMET: B03811
NIKKAJI: J8.522G
LOTUS: LTS0242366
wikidata: Q27108145
KNApSAcK: 8773

分类词条

萘醌类

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

56 个相关的物种来源信息

4362 - Dionaea muscipula: 10.1055/S-2008-1081303
983402 - Diospyros argentea: 10.1016/S0031-9422(00)80490-2
570477 - Diospyros austroafricana:
570478 - Diospyros batocana: 10.1055/S-2007-969969
1932074 - Diospyros blancoi: 10.1016/S0031-9422(00)80490-2
570479 - Diospyros chamaethamnus: 10.1055/S-2006-957464
268838 - Diospyros discolor: 10.1016/S0031-9422(00)80490-2
570484 - Diospyros ebenum:
240001 - Diospyros ferrea:
570485 - Diospyros fischeri:
1367301 - Diospyros greenwayi: 10.1016/S0031-9422(98)00294-5
413749 - Diospyros guianensis:
1085411 - Diospyros hebecarpa: 10.1071/CH9520760
1317788 - Diospyros hoyleana:
1237537 - Diospyros inhacaensis:
35925 - Diospyros kaki:
55363 - Diospyros lotus:
413754 - Diospyros maingayi: 10.1016/S0031-9422(00)80490-2
413757 - Diospyros mannii:
413758 - Diospyros maritima:
1948899 - Diospyros melanoxylon: 10.1016/S0305-1978(98)00061-1
413762 - Diospyros montana:
413763 - Diospyros natalensis:
1465299 - Diospyros revoluta:
570492 - Diospyros rotundifolia:
570496 - Diospyros squarrosa:
268846 - Diospyros sumatrana:
1237540 - Diospyros verrucosa:
13493 - Diospyros virginiana:
589132 - Diospyros wallichii: 10.1016/S0031-9422(00)80490-2
4363 - Drosera: 10.1002/(SICI)1099-1565(199903/04)10:2<64::AID-PCA434>3.0.CO;2-T
173387 - Drosera adelae: 10.1016/0305-1978(94)90045-0
122301 - Drosera aliciae:
173389 - Drosera anglica: 10.1016/0305-1978(94)90045-0
1632261 - Drosera auriculata: 10.1016/0305-1978(94)90045-0
4364 - Drosera binata: 10.3109/13880208909053952
173393 - Drosera burkeana: 10.1016/0305-1978(94)90045-0
4365 - Drosera burmannii: 10.1016/0305-1978(94)90045-0
4366 - Drosera capensis:
173396 - Drosera cistiflora: 10.1016/0305-1978(94)90045-0
173398 - Drosera cuneifolia: 10.1016/0305-1978(94)90045-0
4368 - Drosera filiformis: 10.1016/0305-1978(94)90045-0
173705 - Drosera hamiltonii: 10.1016/0305-1978(94)90045-0
173405 - Drosera hilaris: 10.1016/0305-1978(94)90045-0
16680 - Drosera indica: 10.1016/0305-1978(94)90045-0
463625 - Drosera intermedia:
173410 - Drosera madagascariensis:
4371 - Drosera regia: 10.1016/0305-1978(94)90045-0
173423 - Drosera rotundifolia:
16682 - Drosera stolonifera: 10.1016/0305-1978(94)90045-0
173427 - Drosera trinervia: 10.1016/0305-1978(94)90045-0
173429 - Drosera villosa: 10.1016/0305-1978(94)90045-0
4373 - Drosophyllum lusitanicum: 10.1016/0305-1978(94)90045-0
413790 - Euclea divinorum: 10.1016/S0031-9422(97)00398-1
85202 - Euclea natalensis:
2588161 - Uvaria kirkii: 10.1021/NP50042A028

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Falak Niaz, Muhammad Faheem, Mutiullah Khattak, Iqra Anam Khawaja, Mi-Jeong Ahn, Umakanta Sarker, Syed Babar Jamal, Riaz Ullah, Atif Ali Khan Khalil. Antibacterial and Antibiofilm Activity of Juglone Derivatives against Enterococcus faecalis: An In Silico and In Vitro Approach. BioMed research international. 2022; 2022(?):6197375. doi: 10.1155/2022/6197375. [PMID: 36408282]
Abdur Rauf, Sengul Uysal, Taibi Ben Hadda, Ghias Uddin, Muhammad Asif Nawaz, Haroon Khan, Bina S Siddiqui, Muslim Raza, Saud Bawazeer, Gokhan Zengin. In vivo and in silico sedative-hypnotic like activity of 7-methyljuglone isolated from Diospyros lotus L. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2017 Mar; 87(?):678-682. doi: 10.1016/j.biopha.2017.01.021. [PMID: 28088734]
Anna Kawiak, Ewa Lojkowska. Ramentaceone, a Naphthoquinone Derived from Drosera sp., Induces Apoptosis by Suppressing PI3K/Akt Signaling in Breast Cancer Cells. PloS one. 2016; 11(2):e0147718. doi: 10.1371/journal.pone.0147718. [PMID: 26840401]
Abdur Rauf, Ghias Uddin, Haroon Khan, Bina S Siddiqui, Mohammad Arfan. Anti-hyperalgesic activity of crude extract and 7-methyljuglone of Diospyros lotus roots. Natural product research. 2015; 29(23):2226-9. doi: 10.1080/14786419.2014.1003297. [PMID: 25604725]
Navneet Kishore, Brigitte Binneman, Anita Mahapatra, Maryna van de Venter, Debbie du Plessis-Stoman, Gerhardt Boukes, Peter Houghton, J J Marion Meyer, Namrita Lall. Cytotoxicity of synthesized 1,4-naphthoquinone analogues on selected human cancer cell lines. Bioorganic & medicinal chemistry. 2014 Sep; 22(17):5013-9. doi: 10.1016/j.bmc.2014.06.013. [PMID: 25059501]
Paul A Egan, Frank van der Kooy. Coproduction and ecological significance of naphthoquinones in carnivorous sundews (Drosera). Chemistry & biodiversity. 2012 Jun; 9(6):1033-44. doi: 10.1002/cbdv.201100274. [PMID: 22700223]
Anita Mahapatra, Sannah P N Mativandlela, B Binneman, P B Fourie, Chris J Hamilton, J J M Meyer, F van der Kooy, Peter Houghton, Namrita Lall. Activity of 7-methyljuglone derivatives against Mycobacterium tuberculosis and as subversive substrates for mycothiol disulfide reductase. Bioorganic & medicinal chemistry. 2007 Dec; 15(24):7638-46. doi: 10.1016/j.bmc.2007.08.064. [PMID: 17888665]
N B Bapela, N Lall, P B Fourie, S G Franzblau, C E J Van Rensburg. Activity of 7-methyljuglone in combination with antituberculous drugs against Mycobacterium tuberculosis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2006 Nov; 13(9-10):630-5. doi: 10.1016/j.phymed.2006.08.001. [PMID: 16987644]
Jian-Qiao Gu, Tyler N Graf, Dongho Lee, Hee-Byung Chai, Qiuwen Mi, Leonardus B S Kardono, Fransisca M Setyowati, Rachman Ismail, Soedarsono Riswan, Norman R Farnsworth, Geoffrey A Cordell, John M Pezzuto, Steven M Swanson, David J Kroll, Joseph O Falkinham, Monroe E Wall, Mansukh C Wani, A Douglas Kinghorn, Nicholas H Oberlies. Cytotoxic and antimicrobial constituents of the bark of Diospyros maritima collected in two geographical locations in Indonesia. Journal of natural products. 2004 Jul; 67(7):1156-61. doi: 10.1021/np040027m. [PMID: 15270571]