Lysophosphatidylcholine (BioDeep_00000797153)
natural product
代谢物信息卡片
化学式: C10H22NO7P (299.1134)
中文名称: L-α-溶血磷脂酰胆碱(来自蛋黄)
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)O
InChI: InChI=1S/C10H22NO7P/c1-9(12)16-7-10(13)8-18-19(14,15)17-6-5-11(2,3)4/h10,13H,5-8H2,1-4H3/t10-/m1/s1
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:138424
- PubChem: 5311264
- MeSH: Lysophosphatidylcholines
- CAS: 9008-30-4
- LOTUS: LTS0050737
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
27 个相关的物种来源信息
- 4037 - Apiaceae: LTS0050737
- 9850 - Cervidae: LTS0050737
- 9859 - Cervus: LTS0050737
- 9860 - Cervus elaphus: 10.1248/CPB.35.654
- 9860 - Cervus elaphus: LTS0050737
- 7711 - Chordata: LTS0050737
- 2759 - Eukaryota: LTS0050737
- 52470 - Ferula: LTS0050737
- 82087 - Ferula tenuisecta: 10.1007/BF02282522
- 82087 - Ferula tenuisecta: LTS0050737
- 9604 - Hominidae: LTS0050737
- 9605 - Homo: LTS0050737
- 9606 - Homo sapiens: 10.1007/S11306-015-0840-5
- 9606 - Homo sapiens: LTS0050737
- 3398 - Magnoliopsida: LTS0050737
- 40674 - Mammalia: LTS0050737
- 33208 - Metazoa: LTS0050737
- 4070 - Solanaceae: LTS0050737
- 4107 - Solanum: LTS0050737
- 4081 - Solanum lycopersicum: LTS0050737
- 35493 - Streptophyta: LTS0050737
- 58023 - Tracheophyta: LTS0050737
- 3500 - Urtica: LTS0050737
- 3501 - Urtica dioica: 10.1021/JF9506186
- 3501 - Urtica dioica: LTS0050737
- 3499 - Urticaceae: LTS0050737
- 33090 - Viridiplantae: LTS0050737
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Ryohei Tanaka-Kanegae, Hiroyuki Kimura, Koichiro Hamada. Pharmacokinetics of soy-derived lysophosphatidylcholine compared with that of glycerophosphocholine: a randomized controlled trial.
Bioscience, biotechnology, and biochemistry.
2024 May; 88(6):648-655. doi:
10.1093/bbb/zbae031
. [PMID: 38490741] - Yeon-Hee Kim, Jin-Soo Chung, Hyung-Ho Lee, Jin-Hee Park, Mi-Kyung Kim. Influence of Dietary Polyunsaturated Fatty Acid Intake on Potential Lipid Metabolite Diagnostic Markers in Renal Cell Carcinoma: A Case-Control Study.
Nutrients.
2024 Apr; 16(9):. doi:
10.3390/nu16091265
. [PMID: 38732512] - Blai Morales-Romero, José Manuel González de Aledo-Castillo, Cristina Fernández Sierra, Carmen Martínez Carreira, Carles Zaragoza Bonet, Rosa Fernández Bonifacio, Maria Antònia Caro Miró, Ana Argudo-Ramírez, Rosa María López Galera, Judit García-Villoria. Plasma C24:0- and C26:0-lysophosphatidylcholines are reliable biomarkers for the diagnosis of peroxisomal β-oxidation disorders.
Journal of lipid research.
2024 03; 65(3):100516. doi:
10.1016/j.jlr.2024.100516
. [PMID: 38320654] - Inger Ødum Nielsen, Knut Kristoffer Bundgaard Clemmensen, Ditte Louise Fogde, Tiina Naumanen Dietrich, Jano Dicroce Giacobini, Mesut Bilgin, Marja Jäättelä, Kenji Maeda. Cationic amphiphilic drugs induce accumulation of cytolytic lysoglycerophospholipids in the lysosomes of cancer cells and block their recycling into common membrane glycerophospholipids.
Molecular biology of the cell.
2024 Mar; 35(3):ar25. doi:
10.1091/mbc.e23-06-0263
. [PMID: 38117591] - Romina Gomes, Inês Mendes, Maria Paula Duarte, Narcisa M Bandarra, Ana Gomes-Bispo. New Forms of Neuroactive Phospholipids for DHA Enrichment in Brain.
Marine drugs.
2024 Feb; 22(3):. doi:
10.3390/md22030116
. [PMID: 38535457] - John Koussiouris, Nikita Looby, Max Kotlyar, Vathany Kulasingam, Igor Jurisica, Vinod Chandran. Classifying patients with psoriatic arthritis according to their disease activity status using serum metabolites and machine learning.
Metabolomics : Official journal of the Metabolomic Society.
2024 Jan; 20(1):17. doi:
10.1007/s11306-023-02079-7
. [PMID: 38267619] - Gerard Wong, Kothandaraman Narasimhan, Wei Fun Cheong, Sharon Ng, Izzuddin M Aris, See Ling Loy, Anne K Bendt, Kok Hian Tan, Fabian K P Yap, Lynette P Shek, Yap Seng Chong, Peter D Gluckman, Keith M Godfrey, Yung Seng Lee, Markus R Wenk, Neerja Karnani, Shiao-Yng Chan. Umbilical Cord Plasma Lysophospholipids and Triacylglycerols Associated with Birthweight Percentiles.
Nutrients.
2024 Jan; 16(2):. doi:
10.3390/nu16020274
. [PMID: 38257167] - Sohinee Bhattacharyya, Chet Oon, Luis Diaz, Holly Sandborg, Erin S Stempinski, Michelle Saoi, Terry K Morgan, Claudia S López, Justin R Cross, Mara H Sherman. Autotaxin-lysolipid signaling suppresses a CCL11-eosinophil axis to promote pancreatic cancer progression.
Nature cancer.
2024 Jan; ?(?):. doi:
10.1038/s43018-023-00703-y
. [PMID: 38195933] - Lauren E Louck, Kelly C Cara, Kevin Klatt, Taylor C Wallace, Mei Chung. The Relationship of Circulating Choline and Choline-Related Metabolite Levels with Health Outcomes: A Scoping Review of Genome-Wide Association Studies and Mendelian Randomization Studies.
Advances in nutrition (Bethesda, Md.).
2023 Dec; 15(2):100164. doi:
10.1016/j.advnut.2023.100164
. [PMID: 38128611] - Yuhe Wang, Xu Han, Jingru Shi, Zeqi Liao, Yuanyue Zhang, Yuanyuan Li, Miao Jiang, Meijie Liu. Distinct Metabolites in Osteopenia and Osteoporosis: A Systematic Review and Meta-Analysis.
Nutrients.
2023 Nov; 15(23):. doi:
10.3390/nu15234895
. [PMID: 38068753] - Jing Zhang, Ze Li, Ying Zhang, Yi-Lei Guo, Yan-Rong Zhu, Wen-Xin Xia, Yue Dai, Yu-Feng Xia. Mume Fructus (Prunus mume Sieb. et Zucc.) extract accelerates colonic mucosal healing of mice with colitis induced by dextran sulfate sodium through potentiation of cPLA2-mediated lysophosphatidylcholine synthesis.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2023 Oct; 119(?):154985. doi:
10.1016/j.phymed.2023.154985
. [PMID: 37516090] - Anna Janovicz, Aliz Majer, Mónika Kosztelnik, Miklós Geiszt, Jerold Chun, Satoshi Ishii, Gábor József Tigyi, Zoltán Benyó, Éva Ruisanchez. Autotaxin-lysophosphatidic acid receptor 5 axis evokes endothelial dysfunction via reactive oxygen species signaling.
Experimental biology and medicine (Maywood, N.J.).
2023 10; 248(20):1887-1894. doi:
10.1177/15353702231199081
. [PMID: 37837357] - Yang Liu, Aimin Wu, Ruixia Mo, Qiang Zhou, Lianghui Song, Zheng Li, Hua Zhao, Zhengfeng Fang, Yan Lin, Shengyu Xu, Bin Feng, Yong Zhuo, De Wu, Lianqiang Che. Dietary lysolecithin supplementation improves growth performance of weaned piglets via improving nutrients absorption, lipid metabolism and redox status.
Journal of animal science.
2023 Sep; ?(?):. doi:
10.1093/jas/skad293
. [PMID: 37668533] - Letícia S Martins, Evandro L Duarte, M Teresa Lamy, Julio H K Rozenfeld. DODAB vesicles containing lysophosphatidylcholines: The relevance of acyl chain saturation on the membrane structure and thermal properties.
Biophysical chemistry.
2023 09; 300(?):107075. doi:
10.1016/j.bpc.2023.107075
. [PMID: 37451052] - Rosalie G J Rietjens, Ton J Rabelink. Unveiling the role of Mfsd2a and LPC-DHA in kidney repair.
Journal of lipid research.
2023 09; 64(9):100422. doi:
10.1016/j.jlr.2023.100422
. [PMID: 37549789] - Sarah M Grundmann, Kerstin Ress, Lea Zimmermann, Marcus Höring, Gerhard Liebisch, Erika Most, Robert Ringseis, Klaus Eder. A High-Phosphorus Diet Moderately Alters the Lipidome and Transcriptome in the Skeletal Muscle of Adult Mice.
Nutrients.
2023 Aug; 15(17):. doi:
10.3390/nu15173734
. [PMID: 37686765] - Ying Zhao, Chuanhe Chen, Jianfei Pan, Sin Man Lam, Guanghou Shui, Shulin Yang, Tianwen Wu, Ning Yang, Cong Tao, Jianguo Zhao, Yanfang Wang. Adipocyte Rnf20 ablation increases the fast-twitch fibers of skeletal muscle via lysophosphatidylcholine 16:0.
Cellular and molecular life sciences : CMLS.
2023 Aug; 80(9):243. doi:
10.1007/s00018-023-04896-4
. [PMID: 37555936] - Daisuke Yasuda, Fumie Hamano, Kazuyuki Masuda, Märta Dahlström, Daiki Kobayashi, Nana Sato, Takao Hamakubo, Takao Shimizu, Satoshi Ishii. Inverse agonism of lysophospholipids with cationic head groups at Gi-coupled receptor GPR82.
European journal of pharmacology.
2023 Jun; 954(?):175893. doi:
10.1016/j.ejphar.2023.175893
. [PMID: 37392830] - Ting Xie, Chuxiang Lei, Wei Song, Xunyao Wu, Jianqiang Wu, Fangyuan Li, Yanze Lv, Yuexin Chen, Bao Liu, Yuehong Zheng. Plasma Lipidomics Analysis Reveals the Potential Role of Lysophosphatidylcholines in Abdominal Aortic Aneurysm Progression and Formation.
International journal of molecular sciences.
2023 Jun; 24(12):. doi:
10.3390/ijms241210253
. [PMID: 37373399] - Gabriel Chalhoub, Alina Jamnik, Laura Pajed, Stephanie Kolleritsch, Victoria Hois, Antonia Bagaric, Dominik Prem, Anna Tilp, Dagmar Kolb, Heimo Wolinski, Ulrike Taschler, Thomas Züllig, Gerald N Rechberger, Claudia Fuchs, Michael Trauner, Gabriele Schoiswohl, Guenter Haemmerle. Carboxylesterase 2a deletion provokes hepatic steatosis and insulin resistance in mice involving impaired diacylglycerol and lysophosphatidylcholine catabolism.
Molecular metabolism.
2023 06; 72(?):101725. doi:
10.1016/j.molmet.2023.101725
. [PMID: 37059417] - Liangyu Xue, Yunjiao Zhao, Huiting Wang, Zongqi Li, Tao Wu, Rui Liu, Wenjie Sui, Min Zhang. The effects of live and pasteurized Akkermansia muciniphila on DSS-induced ulcerative colitis, gut microbiota, and metabolomics in mice.
Food & function.
2023 May; 14(10):4632-4646. doi:
10.1039/d2fo03493j
. [PMID: 37098829] - April Rees, Zoe Edwards-I-Coll, Oliver Richards, Molly E Raikes, Roberto Angelini, Catherine A Thornton. The dynamic inflammatory profile of pregnancy can be monitored using a novel lipid-based mass spectrometry technique.
Molecular omics.
2023 05; 19(4):340-350. doi:
10.1039/d2mo00294a
. [PMID: 36883215] - Chi Nguyen, Hsiang-Ting Lei, Louis Tung Faat Lai, Marc J Gallenito, Xuelang Mu, Doreen Matthies, Tamir Gonen. Lipid flipping in the omega-3 fatty-acid transporter.
Nature communications.
2023 May; 14(1):2571. doi:
10.1038/s41467-023-37702-7
. [PMID: 37156797] - H S Liu, Z Wu, R Y Yang, G Z Chen, Y Li, Q Zhou, H P Yuan, Z Yang, L Sun. [Association between serum lysophosphatidylcholine level and elderly health index in older people from longevity areas of Guangxi Province].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine].
2023 May; 57(5):649-653. doi:
10.3760/cma.j.cn112150-20221124-01144
. [PMID: 37165812] - Miguel Benítez-Angeles, Ana E López Romero, Itzel Llorente, Ileana Hernández-Araiza, Ariela Vergara-Jaque, Fernando H Real, Óscar Eduardo Gutiérrez Castañeda, Marcelino Arciniega, Luis E Morales-Buenrostro, Francisco Torres-Quiroz, Refugio García-Villegas, Luis B Tovar-Y-Romo, Wolfgang B Liedtke, León D Islas, Tamara Rosenbaum. Modes of action of lysophospholipids as endogenous activators of the TRPV4 ion channel.
The Journal of physiology.
2023 05; 601(9):1655-1673. doi:
10.1113/jp284262
. [PMID: 36625071] - Juntong Wei, Xiaoyu Liu, Weimin Xiao, Jiahua Lu, Li Guan, Zhangfu Fang, Jiaping Chen, Baoqing Sun, Zongwei Cai, Xizhuo Sun, Hua-Ling Chen, Nanshan Zhong, Zhigang Liu, Jun Yang, Xiaojun Xiao, Shau-Ku Huang. Phospholipid remodeling and its derivatives are associated with COVID-19 severity.
The Journal of allergy and clinical immunology.
2023 05; 151(5):1259-1268. doi:
10.1016/j.jaci.2022.11.032
. [PMID: 36736798] - Dalal Mohamad Ali, Kevin Hogeveen, Rose-Marie Orhant, Tiphaine Le Gal de Kerangal, Françoise Ergan, Lionel Ulmann, Gaëlle Pencreac'h. Lysophosphatidylcholine-DHA Specifically Induces Cytotoxic Effects of the MDA-MB-231 Human Breast Cancer Cell Line In Vitro-Comparative Effects with Other Lipids Containing DHA.
Nutrients.
2023 Apr; 15(9):. doi:
10.3390/nu15092137
. [PMID: 37432249] - Pinaki Chaudhuri, Priya Putta, Michael A Rosenbaum, Linda M Graham. p38 MAPK activation and STIM1-Orai3 association mediate TRPC6 externalization.
American journal of physiology. Cell physiology.
2023 Apr; ?(?):. doi:
10.1152/ajpcell.00425.2022
. [PMID: 37093037] - Arnab Chattopadhyay, Pallavi Mukherjee, Dawoud Sulaiman, Huan Wang, Victor Girjalva, Nasrin Dorreh, Jonathan P Jacobs, Samuel Delk, Wouter H Moolenaar, Mohamad Navab, Srinivasa T Reddy, Alan M Fogelman. Role of Enterocyte Enpp2 and Autotaxin in Regulating Lipopolysaccharide Levels, Systemic Inflammation and Atherosclerosis.
Journal of lipid research.
2023 Apr; ?(?):100370. doi:
10.1016/j.jlr.2023.100370
. [PMID: 37059333] - Shi-Hui Law, Hua-Chen Chan, Guan-Ming Ke, Swetha Kamatam, Gopal Kedihithlu Marathe, Vinoth Kumar Ponnusamy, Liang-Yin Ke. Untargeted Lipidomic Profiling Reveals Lysophosphatidylcholine and Ceramide as Atherosclerotic Risk Factors in apolipoprotein E Knockout Mice.
International journal of molecular sciences.
2023 Apr; 24(8):. doi:
10.3390/ijms24086956
. [PMID: 37108120] - Priya Putta, Pinaki Chaudhuri, Rocio Guardia-Wolff, Michael A Rosenbaum, Linda M Graham. iPLA2 inhibition blocks LysoPC-induced TRPC6 externalization and promotes Re-endothelialization of carotid injuries in hypercholesterolemic mice.
Cell calcium.
2023 Apr; 112(?):102734. doi:
10.1016/j.ceca.2023.102734
. [PMID: 37030190] - Helison Rafael P Carmo, Marcos Y Yoshinaga, Alejandro Rosell Castillo, Adriano Britto Chaves-Filho, Isabella Bonilha, Joaquim Barreto, Stéfanie Primon Muraro, Gabriela Fabiano de Souza, Gustavo Gastão Davanzo, Maurício W Perroud, Kishal Lukhna, Mpiko Ntsekhe, Sean Davidson, Licio A Velloso, Wilson Nadruz, Luiz Sérgio F Carvalho, Miguel Sáinz-Jaspeado, Alessandro S Farias, José Luiz Proença-Módena, Pedro M Moraes-Vieira, Sotirios K Karathanasis, Derek Yellon, Sayuri Miyamoto, Alan T Remaley, Andrei C Sposito. Phenotypic changes in low-density lipoprotein particles as markers of adverse clinical outcomes in COVID-19.
Molecular genetics and metabolism.
2023 04; 138(4):107552. doi:
10.1016/j.ymgme.2023.107552
. [PMID: 36889041] - Jifang Liang, Jing Li, Junkun Zhang, Jianrong Rong, Xiuzhe Wang, Caixia Zhao, Hailong Zhang, Haipeng Shi, Weidong Wu. UHPLC-MS/MS-based untargeted lipidomics analysis of septic patients.
Clinica chimica acta; international journal of clinical chemistry.
2023 Apr; 544(?):117336. doi:
10.1016/j.cca.2023.117336
. [PMID: 37031781] - Paula Emília Nunes Ribeiro Bellot, Melissa Nunes Moia, Bruna Zavarize Reis, Lucia Fatima Campos Pedrosa, Ljubica Tasic, Fernando Barbosa, Karine Cavalcanti Maurício Sena-Evangelista. Are Phosphatidylcholine and Lysophosphatidylcholine Body Levels Potentially Reliable Biomarkers in Obesity? A Review of Human Studies.
Molecular nutrition & food research.
2023 04; 67(7):e2200568. doi:
10.1002/mnfr.202200568
. [PMID: 36707969] - Jing-Gang Xia, Bowen Li, Hao Zhang, Qin-Xue Li, Sin Man Lam, Chun-Lin Yin, He Tian, Guanghou Shui. Precise Metabolomics Defines Systemic Metabolic Dysregulation Distinct to Acute Myocardial Infarction Associated With Diabetes.
Arteriosclerosis, thrombosis, and vascular biology.
2023 04; 43(4):581-596. doi:
10.1161/atvbaha.122.318871
. [PMID: 36727520] - Francesca M Trovato, Rabiya Zia, Florent Artru, Salma Mujib, Ellen Jerome, Anna Cavazza, Muireann Coen, Ian Wilson, Elaine Holmes, Phillip Morgan, Arjuna Singanayagam, Christine Bernsmeier, Salvatore Napoli, William Bernal, Julia Wendon, Rosa Miquel, Krishna Menon, Vishal C Patel, John Smith, Stephen R Atkinson, Evangelos Triantafyllou, Mark J W McPhail. Lysophosphatidylcholines modulate immunoregulatory checkpoints in peripheral monocytes and are associated with mortality in people with acute liver failure.
Journal of hepatology.
2023 Mar; 78(3):558-573. doi:
10.1016/j.jhep.2022.10.031
. [PMID: 36370949] - Nao Sugimoto, Yoshifumi Morita, Eri Sakai, Yutaka Yatomi, Makoto Kurano. Modulations of urinary lipid mediators in acute bladder cystitis.
Prostaglandins & other lipid mediators.
2023 02; 164(?):106690. doi:
10.1016/j.prostaglandins.2022.106690
. [PMID: 36332874] - Yoshibumi Shimizu, Keiko Tamiya-Koizumi, Toshihiko Tsutsumi, Mamoru Kyogashima, Reiji Kannagi, Soichiro Iwaki, Mineyoshi Aoyama, Akira Tokumura. Hypoxia increases cellular levels of phosphatidic acid and lysophospholipids in undifferentiated Caco-2 cells.
Lipids.
2023 Jan; ?(?):. doi:
10.1002/lipd.12366
. [PMID: 36708255] - Daniele Chaves-Moreira, Luiza Helena Gremski, Fábio Rogério de Moraes, Larissa Vuitika, Ana Carolina Martins Wille, Jorge Enrique Hernández González, Olga Meiri Chaim, Andrea Senff-Ribeiro, Raghuvir Krishnaswamy Arni, Silvio Sanches Veiga. Brown Spider Venom Phospholipase-D Activity upon Different Lipid Substrates.
Toxins.
2023 01; 15(2):. doi:
10.3390/toxins15020109
. [PMID: 36828423] - João P Monteiro, Helena B Ferreira, Tânia Melo, Carla Flanagan, Nuno Urbani, João Neves, Pedro Domingues, M Rosário Domingues. The plasma phospholipidome of the bottlenose dolphin (Tursiops truncatus) is modulated by both sex and developmental stage.
Molecular omics.
2023 01; 19(1):35-47. doi:
10.1039/d2mo00202g
. [PMID: 36314173] - Bijay Banstola, Prabhath L Gamage, Wenlei Jiang, Thilak Mudalige. Analysis of phospholipids and triacylglycerols in intravenous lipid emulsions.
Journal of pharmaceutical and biomedical analysis.
2023 Jan; 222(?):115112. doi:
10.1016/j.jpba.2022.115112
. [PMID: 36274478] - Linlin Zhang, Xuanqi Liu, Yifei Liu, Furong Yan, Yiming Zeng, Yuanlin Song, Hao Fang, Dongli Song, Xiangdong Wang. Lysophosphatidylcholine inhibits lung cancer cell proliferation by regulating fatty acid metabolism enzyme long-chain acyl-coenzyme A synthase 5.
Clinical and translational medicine.
2023 01; 13(1):e1180. doi:
10.1002/ctm2.1180
. [PMID: 36639836] - Anne-Claire Duchez, Sébastien Fauteux-Daniel, Caroline Sut, Theo Ebermeyer, Marco Heestermans, Charles-Antoine Arthaud, Marie-Ange Eyraud, Amélie Prier, Estelle Audoux, Justine Bertrand-Michel, Bernard Payrastre, Olivier Garraud, Eric Boilard, Hind Hamzeh-Cognasse, Fabrice Cognasse. Bioactive lipids as biomarkers of adverse reactions associated with apheresis platelet concentrate transfusion.
Frontiers in immunology.
2023; 14(?):1031968. doi:
10.3389/fimmu.2023.1031968
. [PMID: 37138863] - Haitao Chen, Chenxiao Ye, Changhong Wu, Jiali Zhang, Lu Xu, Xuanying Wang, Chao Xu, Jin Zhang, Yong Guo, Qinghua Yao. Berberine inhibits high fat diet-associated colorectal cancer through modulation of the gut microbiota-mediated lysophosphatidylcholine.
International journal of biological sciences.
2023; 19(7):2097-2113. doi:
10.7150/ijbs.81824
. [PMID: 37151876] - Núria Puig, Jose Rives, Montserrat Estruch, Ana Aguilera-Simon, Noemi Rotllan, Mercedes Camacho, Núria Colomé, Francesc Canals, José Luis Sánchez-Quesada, Sonia Benitez. Presence of Ceramidase Activity in Electronegative LDL.
International journal of molecular sciences.
2022 Dec; 24(1):. doi:
10.3390/ijms24010165
. [PMID: 36613609] - Toshihiko Tsutsumi, Katsuhiko Yasuda, Mariko Neya, Hidetaka Okada, Akira Tokumura. Lysophosphatidic acid production from lysophosphatidylcholine by lysophospholipase D activity of autotaxin in plasma of women with normal and adverse pregnancies.
Prostaglandins & other lipid mediators.
2022 12; 163(?):106670. doi:
10.1016/j.prostaglandins.2022.106670
. [PMID: 35963509] - Kai Shan, Ninghan Feng, Doudou Zhu, Hongyan Qu, Guoling Fu, Jiaqi Li, Jing Cui, Heyan Chen, Rong Wang, Yumin Qi, Yong Q Chen. Free docosahexaenoic acid promotes ferroptotic cell death via lipoxygenase dependent and independent pathways in cancer cells.
European journal of nutrition.
2022 Dec; 61(8):4059-4075. doi:
10.1007/s00394-022-02940-w
. [PMID: 35804267] - Jinxue Wei, Zijian Zhang, Yue Du, Xiao Yang, Liansheng Zhao, Peiyan Ni, Rongjun Ni, Meng Gong, Xiaohong Ma. A combination of neuroimaging and plasma metabolomic analysis suggests inflammation is associated with white matter structural connectivity in major depressive disorder.
Journal of affective disorders.
2022 12; 318(?):7-15. doi:
10.1016/j.jad.2022.08.108
. [PMID: 36057287] - Song Cang, Ran Liu, Kunqian Mu, Qi Tang, Haiyue Cui, Kaishun Bi, Yiwen Zhang, Qing Li. Assessment of plasma amino acids, purines, tricarboxylic acid cycle metabolites, and lipids levels in NSCLC patients based on LC-MS/MS quantification.
Journal of pharmaceutical and biomedical analysis.
2022 Nov; 221(?):114990. doi:
10.1016/j.jpba.2022.114990
. [PMID: 36208488] - Paul Cressey, Wasim Abuillan, Nada Ibrahim, Jana Alhoussein, Oleg Konovalov, Gang Zheng, Ali Makky. Self-Organization of Lipid-Porphyrin Conjugates at the Air/Water Interface.
Chemphyschem : a European journal of chemical physics and physical chemistry.
2022 Nov; ?(?):e202200687. doi:
10.1002/cphc.202200687
. [PMID: 36412498] - Min Zhou, Chen Li, Xue Han, Bohan Yu, Xiang-Zhen Yan, Yan Zhang, Xiao-Juan Yang. Lipidomic analysis reveals altered lipid profiles of gingival tissues with periodontitis.
Journal of clinical periodontology.
2022 11; 49(11):1192-1202. doi:
10.1111/jcpe.13710
. [PMID: 35924763] - Xuedan Deng, Changfu Hao, Yiping Li, Yonghua Guo, Huifang Si, Jing He, Meng Deng, Zhuoya Niu, Chen Wang, Xiao Xu, Kai Dai, Wu Yao. Lysophosphatidylcholine acyltransferase 1 alleviates silica-induced pulmonary fibrosis by modulating lipid metabolism.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2022 Nov; 155(?):113638. doi:
10.1016/j.biopha.2022.113638
. [PMID: 36099794] - Wan-Jun Yang, Rong-Chang Cao, Wang Xiao, Xiao-Lou Zhang, Hao Xu, Meng Wang, Zhi-Tao Zhou, Huo-Ji Chen, Jia Xu, Xue-Mei Chen, Jun-Ling Zeng, Shu-Ji Li, Min Luo, Yan-Jiang Han, Xiao-Bing Yang, Guo-Dong Feng, Yu-Heng Lu, Yuan-Yuan Ni, Chan-Gui Wu, Jun-Jie Bai, Zi-Qi Yuan, Jin Jin, Guo-Wei Zhang. Acinar ATP8b1/LPC pathway promotes macrophage efferocytosis and clearance of inflammation during chronic pancreatitis development.
Cell death & disease.
2022 10; 13(10):893. doi:
10.1038/s41419-022-05322-6
. [PMID: 36273194] - Sihui Li, Xing Luo, Zhangbin Liao, Mengqing Liang, Houguo Xu, Kangsen Mai, Yanjiao Zhang. Effects of Lysophosphatidylcholine on Intestinal Health of Turbot Fed High-Lipid Diets.
Nutrients.
2022 Oct; 14(20):. doi:
10.3390/nu14204398
. [PMID: 36297082] - Daniel Gonzalez Izundegui, Patricia E Miller, Ravi V Shah, Clary B Clish, Maura E Walker, Gary F Mitchell, Robert E Gerszten, Martin G Larson, Ramachandran S Vasan, Matthew Nayor. Response of circulating metabolites to an oral glucose challenge and risk of cardiovascular disease and mortality in the community.
Cardiovascular diabetology.
2022 10; 21(1):213. doi:
10.1186/s12933-022-01647-w
. [PMID: 36243866] - Stephanie S Chassen, Karin Zemski-Berry, Stefanie Raymond-Whish, Camille Driver, John C Hobbins, Theresa L Powell. Altered Cord Blood Lipid Concentrations Correlate with Birth Weight and Doppler Velocimetry of Fetal Vessels in Human Fetal Growth Restriction Pregnancies.
Cells.
2022 10; 11(19):. doi:
10.3390/cells11193110
. [PMID: 36231072] - Yi Wang, Ping Wu, Yichao Huang, Yi Ye, Xue Yang, Fengjiang Sun, Yi-Xiang Ye, Yuwei Lai, Jing Ouyang, Linjing Wu, Yue Li, Yanqin Li, Bin Zhao, Yixin Wang, Gang Liu, Xiong-Fei Pan, Da Chen, An Pan. BMI and lipidomic biomarkers with risk of gestational diabetes in pregnant women.
Obesity (Silver Spring, Md.).
2022 10; 30(10):2044-2054. doi:
10.1002/oby.23517
. [PMID: 36046944] - Makoto Kurano, Koh Okamoto, Daisuke Jubishi, Hideki Hashimoto, Eri Sakai, Daisuke Saigusa, Kuniyuki Kano, Junken Aoki, Sohei Harada, Shu Okugawa, Kent Doi, Kyoji Moriya, Yutaka Yatomi. Dynamic modulations of sphingolipids and glycerophospholipids in COVID-19.
Clinical and translational medicine.
2022 10; 12(10):e1069. doi:
10.1002/ctm2.1069
. [PMID: 36214754] - Hiroki Kawana, Masaya Ozawa, Takeaki Shibata, Hirofumi Onishi, Yukitaka Sato, Kuniyuki Kano, Hideo Shindou, Takao Shimizu, Nozomu Kono, Junken Aoki. Identification and characterization of LPLAT7 as an sn-1-specific lysophospholipid acyltransferase.
Journal of lipid research.
2022 10; 63(10):100271. doi:
10.1016/j.jlr.2022.100271
. [PMID: 36049524] - Julia Hernández Lluesa, Luis Carlos López-Romero, José Jesús Broseta Monzó, Marta Roca Marugán, Iris Viejo Boyano, Diana Rodríguez-Espinosa, Aina Gómez-Bori, Amparo Soldevila Orient, Ramón Devesa Such, Pilar Sánchez Perez, Julio Hernández Jaras. Lipidic profiles of patients starting peritoneal dialysis suggest an increased cardiovascular risk beyond classical dyslipidemia biomarkers.
Scientific reports.
2022 09; 12(1):16394. doi:
10.1038/s41598-022-20757-9
. [PMID: 36180468] - Diya Shi, Congshu Feng, Jinhai Xie, Xi Zhang, HongLian Dai, Lesan Yan. Recent progress of nanomedicine in secreted phospholipase A2 as a potential therapeutic target.
Journal of materials chemistry. B.
2022 09; 10(37):7349-7360. doi:
10.1039/d2tb00608a
. [PMID: 35770707] - Yingmei Luo, Juan Li, Chaobo Huang, Xuefeng Wang, Dingxin Long, Yi Cao. Graphene oxide links alterations of anti-viral signaling pathways with lipid metabolism via suppressing TLR3 in vascular smooth muscle cells.
Molecular omics.
2022 09; 18(8):779-790. doi:
10.1039/d2mo00086e
. [PMID: 35912640] - Arjun H Banskota, Alysson Jones, Joseph P M Hui, Roumiana Stefanova, Ian W Burton. Analysis of Polar Lipids in Hemp (Cannabis sativa L.) By-Products by Ultra-High Performance Liquid Chromatography and High-Resolution Mass Spectrometry.
Molecules (Basel, Switzerland).
2022 Sep; 27(18):. doi:
10.3390/molecules27185856
. [PMID: 36144592] - Farsad Afshinnia, Evan L Reynolds, Thekkelnaycke M Rajendiran, Tanu Soni, Jaeman Byun, Masha G Savelieff, Helen C Looker, Robert G Nelson, George Michailidis, Brian C Callaghan, Subramaniam Pennathur, Eva L Feldman. Serum lipidomic determinants of human diabetic neuropathy in type 2 diabetes.
Annals of clinical and translational neurology.
2022 09; 9(9):1392-1404. doi:
10.1002/acn3.51639
. [PMID: 35923113] - Peiyu Xu, Sijie Huang, Shimeng Guo, Ying Yun, Xi Cheng, Xinheng He, Pengjun Cai, Yuan Lan, Hu Zhou, Hualiang Jiang, Yi Jiang, Xin Xie, H Eric Xu. Structural identification of lysophosphatidylcholines as activating ligands for orphan receptor GPR119.
Nature structural & molecular biology.
2022 09; 29(9):863-870. doi:
10.1038/s41594-022-00816-5
. [PMID: 35970999] - Ting Zeng, Rong Zhang, Yanyan Chen, Wenjing Guo, Jianing Wang, Zongwei Cai. In situ localization of lipids on mouse kidney tissues with acute cadmium toxicity using atmospheric pressure-MALDI mass spectrometry imaging.
Talanta.
2022 Aug; 245(?):123466. doi:
10.1016/j.talanta.2022.123466
. [PMID: 35460980] - Jinxuan Ren, Jiaqi Lin, Lina Yu, Min Yan. Lysophosphatidylcholine: Potential Target for the Treatment of Chronic Pain.
International journal of molecular sciences.
2022 Jul; 23(15):. doi:
10.3390/ijms23158274
. [PMID: 35955410] - Miao Weng, Wencong Zhang, Zhou Zhang, Yuhang Tang, Wencong Lai, Zhijie Dan, Yongtao Liu, Jichang Zheng, Shengnan Gao, Kangsen Mai, Qinghui Ai. Effects of dietary lysolecithin on growth performance, serum biochemical indexes, antioxidant capacity, lipid metabolism and inflammation-related genes expression of juvenile large yellow croaker (Larimichthys crocea).
Fish & shellfish immunology.
2022 Jul; ?(?):. doi:
10.1016/j.fsi.2022.07.020
. [PMID: 35843522] - Sara T Humes, Nicole Iovine, Cindy Prins, Timothy J Garrett, John A Lednicky, Eric S Coker, Tara Sabo-Attwood. Association between lipid profiles and viral respiratory infections in human sputum samples.
Respiratory research.
2022 Jul; 23(1):177. doi:
10.1186/s12931-022-02091-w
. [PMID: 35780155] - Sean Bennet, Martin Kaufmann, Kaede Takami, Calvin Sjaarda, Katya Douchant, Emily Moslinger, Henry Wong, David E Reed, Anne K Ellis, Stephen Vanner, Robert I Colautti, Prameet M Sheth. Small-molecule metabolome identifies potential therapeutic targets against COVID-19.
Scientific reports.
2022 Jun; 12(1):10029. doi:
10.1038/s41598-022-14050-y
. [PMID: 35705626] - Zheng Wang, Brandilyn A Peters, Mykhaylo Usyk, Jiaqian Xing, David B Hanna, Tao Wang, Wendy S Post, Alan L Landay, Howard N Hodis, Kathleen Weber, Audrey French, Elizabeth T Golub, Jason Lazar, Deborah Gustafson, Seble Kassaye, Bradley Aouizerat, Sabina Haberlen, Carlos Malvestutto, Matthew Budoff, Steven M Wolinsky, Anjali Sharma, Kathryn Anastos, Clary B Clish, Robert C Kaplan, Robert D Burk, Qibin Qi. Gut Microbiota, Plasma Metabolomic Profiles, and Carotid Artery Atherosclerosis in HIV Infection.
Arteriosclerosis, thrombosis, and vascular biology.
2022 Jun; ?(?):101161ATVBAHA121317276. doi:
10.1161/atvbaha.121.317276
. [PMID: 35678187] - Maria Martinez-Molledo, Emmanuel Nji, Nicolas Reyes. Structural insights into the lysophospholipid brain uptake mechanism and its inhibition by syncytin-2.
Nature structural & molecular biology.
2022 06; 29(6):604-612. doi:
10.1038/s41594-022-00786-8
. [PMID: 35710838] - Francesca Di Cesare, Claudio Luchinat, Leonardo Tenori, Edoardo Saccenti. Age- and Sex-Dependent Changes of Free Circulating Blood Metabolite and Lipid Abundances, Correlations, and Ratios.
The journals of gerontology. Series A, Biological sciences and medical sciences.
2022 05; 77(5):918-926. doi:
10.1093/gerona/glab335
. [PMID: 34748631] - Hui Wang, Yang Wang, Jie-Yun Song, Ping-Ping Zhang, Qi-Ying Song, Chen-Xiong Li, Li Li, Hai-Jun Wang. Associations of genetic variants of lysophosphatidylcholine metabolic enzymes with levels of serum lipids.
Pediatric research.
2022 05; 91(6):1595-1599. doi:
10.1038/s41390-021-01549-9
. [PMID: 33935285] - Xiaofei Yin, David Mongan, Mary Cannon, Stanley Zammit, Tuulia Hyötyläinen, Matej Orešič, Lorraine Brennan, David R Cotter. Plasma lipid alterations in young adults with psychotic experiences: A study from the Avon Longitudinal Study of Parents and Children cohort.
Schizophrenia research.
2022 05; 243(?):78-85. doi:
10.1016/j.schres.2022.02.029
. [PMID: 35245705] - Li Meng, Ruiyue Yang, Daguang Wang, Wenbin Wu, Jing Shi, Ji Shen, Yamin Dang, Guoqing Fan, Hong Shi, Jun Dong, Huan Xi, Pulin Yu. Specific lysophosphatidylcholine and acylcarnitine related to sarcopenia and its components in older men.
BMC geriatrics.
2022 03; 22(1):249. doi:
10.1186/s12877-022-02953-4
. [PMID: 35337292] - Lijie Li, Qi Zhan, Kaikai Yi, Ning Chen, Xueping Li, Shixue Yang, Xin Hou, Jin Zhao, Xubo Yuan, Chunsheng Kang. Engineering Lipusu with lysophosphatidylcholine for improved tumor cellular uptake and anticancer efficacy.
Journal of materials chemistry. B.
2022 03; 10(11):1833-1842. doi:
10.1039/d1tb02823e
. [PMID: 35212350] - Mitsuaki Nishikimi, Muhammad Shoaib, Rishabh C Choudhary, Tomoaki Aoki, Santiago J Miyara, Tsukasa Yagi, Kei Hayashida, Ryosuke Takegawa, Tai Yin, Lance B Becker, Junhwan Kim. Preserving Brain LPC-DHA by Plasma Supplementation Attenuates Brain Injury after Cardiac Arrest.
Annals of neurology.
2022 03; 91(3):389-403. doi:
10.1002/ana.26296
. [PMID: 34979595] - Bernice H Wong, Ding Mei, Geok Lin Chua, Dwight L Galam, Markus R Wenk, Federico Torta, David L Silver. The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis.
The Journal of biological chemistry.
2022 03; 298(3):101709. doi:
10.1016/j.jbc.2022.101709
. [PMID: 35150739] - Kentaro Yoshioka, Yosuke Hirakawa, Makoto Kurano, Yuko Ube, Yoko Ono, Kensuke Kojima, Taiga Iwama, Kuniyuki Kano, Sho Hasegawa, Tsuyoshi Inoue, Takashi Shimada, Junken Aoki, Yutaka Yatomi, Masaomi Nangaku, Reiko Inagi. Lysophosphatidylcholine mediates fast decline in kidney function in diabetic kidney disease.
Kidney international.
2022 03; 101(3):510-526. doi:
10.1016/j.kint.2021.10.039
. [PMID: 34856312] - Caixia Zang, Hui Liu, Cheng Ju, Fangyu Yuan, Jingwen Ning, Meiyu Shang, Xiuqi Bao, Yang Yu, Xinsheng Yao, Dan Zhang. Gardenia jasminoides J. Ellis extract alleviated white matter damage through promoting the differentiation of oligodendrocyte precursor cells via suppressing neuroinflammation.
Food & function.
2022 Feb; 13(4):2131-2141. doi:
10.1039/d1fo02127c
. [PMID: 35112688] - Mitsuaki Nishikimi, Tsukasa Yagi, Muhammad Shoaib, Ryosuke Takegawa, Rehana Rasul, Kei Hayashida, Yu Okuma, Tai Yin, Rishabh C Choudhary, Lance B Becker, Junhwan Kim. Phospholipid Screening Postcardiac Arrest Detects Decreased Plasma Lysophosphatidylcholine: Supplementation as a New Therapeutic Approach.
Critical care medicine.
2022 02; 50(2):e199-e208. doi:
10.1097/ccm.0000000000005180
. [PMID: 34259447] - Si Yang, Jie Chen, Bingchun Ma, Jinglei Wang, Jiaxiang Chen. Role of Autophagy in Lysophosphatidylcholine-Induced Apoptosis of Mouse Ovarian Granulosa Cells.
International journal of molecular sciences.
2022 Jan; 23(3):. doi:
10.3390/ijms23031479
. [PMID: 35163399] - Denise Wolrab, Robert Jirásko, Eva Cífková, Marcus Höring, Ding Mei, Michaela Chocholoušková, Ondřej Peterka, Jakub Idkowiak, Tereza Hrnčiarová, Ladislav Kuchař, Robert Ahrends, Radana Brumarová, David Friedecký, Gabriel Vivo-Truyols, Pavel Škrha, Jan Škrha, Radek Kučera, Bohuslav Melichar, Gerhard Liebisch, Ralph Burkhardt, Markus R Wenk, Amaury Cazenave-Gassiot, Petr Karásek, Ivo Novotný, Kristína Greplová, Roman Hrstka, Michal Holčapek. Lipidomic profiling of human serum enables detection of pancreatic cancer.
Nature communications.
2022 01; 13(1):124. doi:
10.1038/s41467-021-27765-9
. [PMID: 35013261] - Jetjamnong Sueajai, Nareerat Sutjarit, Nittaya Boonmuen, Saranya Auparakkitanon, Nantida Noumjad, Apichart Suksamrarn, Nawaporn Vinayavekhin, Pawinee Piyachaturawat. Lowering of lysophosphatidylcholines in ovariectomized rats by Curcuma comosa.
PloS one.
2022; 17(5):e0268179. doi:
10.1371/journal.pone.0268179
. [PMID: 35588422] - Hao-Yu Li, Yang Zou, Hany M Elsheikha, Yue Xu, Lang Cai, Shi-Chen Xie, Xing-Quan Zhu, Wen-Bin Zheng. Lipidomic changes in the liver of beagle dogs associated with Toxocara canis infection.
Frontiers in cellular and infection microbiology.
2022; 12(?):890589. doi:
10.3389/fcimb.2022.890589
. [PMID: 36176575] - Dan Su, Liangliang Liao, Qiang Zeng, Zhou Liao, Yali Liu, Chen Jin, Genhua Zhu, Changlian Chen, Ming Yang, Zhifu Ai, Yonggui Song. Study on the new anti-atherosclerosis activity of different Herba patriniae through down-regulating lysophosphatidylcholine of the glycerophospholipid metabolism pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2022 Jan; 94(?):153833. doi:
10.1016/j.phymed.2021.153833
. [PMID: 34798520] - Cong Hu, Hong-Wei Li, Jia-Qun Ke, Xue-Chun Yu, Mei-Yu Zhao, Xin-Yue Shi, Lin-Jing Wu, Xi-Lan Tang, Yin-Hua Xiong. Metabolic profiling of lysophosphatidylcholines in chlorpromazine hydrochloride- and N-acetyl-p-amino-phenoltriptolide-induced liver injured rats based on ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry.
Human & experimental toxicology.
2022 Jan; 41(?):9603271221108320. doi:
10.1177/09603271221108320
. [PMID: 35722787] - Katherine E Havranek, Judith Mary Reyes Ballista, Kelly Marie Hines, Melinda Ann Brindley. Untargeted Lipidomics of Vesicular Stomatitis Virus-Infected Cells and Viral Particles.
Viruses.
2021 12; 14(1):. doi:
10.3390/v14010003
. [PMID: 35062207] - Thomas Boehm, Robin Ristl, Saijo Joseph, Karin Petroczi, Kristaps Klavins, Peter Valent, Bernd Jilma. Metabolome and lipidome derangements during a severe mast cell activation event in a patient with indolent systemic mastocytosis.
The Journal of allergy and clinical immunology.
2021 12; 148(6):1533-1544. doi:
10.1016/j.jaci.2021.03.043
. [PMID: 33864889] - Qian Zhang, Wei Zhang, Jing Liu, Haisen Yang, Yuxia Hu, Mengdi Zhang, Tuya Bai, Fuhou Chang. Lysophosphatidylcholine promotes intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 expression in human umbilical vein endothelial cells via an orphan G protein receptor 2-mediated signaling pathway.
Bioengineered.
2021 12; 12(1):4520-4535. doi:
10.1080/21655979.2021.1956671
. [PMID: 34346841] - Yifan Lu, Gayani Nanayakkara, Yu Sun, Lu Liu, Keman Xu, Charles Drummer, Ying Shao, Fatma Saaoud, Eric T Choi, Xiaohua Jiang, Hong Wang, Xiaofeng Yang. Procaspase-1 patrolled to the nucleus of proatherogenic lipid LPC-activated human aortic endothelial cells induces ROS promoter CYP1B1 and strong inflammation.
Redox biology.
2021 11; 47(?):102142. doi:
10.1016/j.redox.2021.102142
. [PMID: 34598017] - Wei Jia, Ruiting Li, Xixuan Wu, Shuxing Liu, Lin Shi. UHPLC-Q-Orbitrap HRMS-based quantitative lipidomics reveals the chemical changes of phospholipids during thermal processing methods of Tan sheep meat.
Food chemistry.
2021 Oct; 360(?):130153. doi:
10.1016/j.foodchem.2021.130153
. [PMID: 34034056] - Magdalena Przybyło, Dominik Drabik, Joanna Doskocz, Aleš Iglič, Marek Langner. The Effect of the Osmotically Active Compound Concentration Difference on the Passive Water and Proton Fluxes across a Lipid Bilayer.
International journal of molecular sciences.
2021 Oct; 22(20):. doi:
10.3390/ijms222011099
. [PMID: 34681757] - Yvonne N Flores, Aryana T Amoon, Baolong Su, Rafael Velazquez-Cruz, Paula Ramírez-Palacios, Jorge Salmerón, Berenice Rivera-Paredez, Janet S Sinsheimer, Aldons J Lusis, Adriana Huertas-Vazquez, Sammy Saab, Beth A Glenn, Folasade P May, Kevin J Williams, Roshan Bastani, Steven J Bensinger. Serum lipids are associated with nonalcoholic fatty liver disease: a pilot case-control study in Mexico.
Lipids in health and disease.
2021 Oct; 20(1):136. doi:
10.1186/s12944-021-01526-5
. [PMID: 34629052] - Xin Li, Kenji Nakayama, Takayuki Goto, Hiroko Kimura, Shusuke Akamatsu, Yujiro Hayashi, Kazutoshi Fujita, Takashi Kobayashi, Koji Shimizu, Norio Nonomura, Osamu Ogawa, Takahiro Inoue. High level of phosphatidylcholines/lysophosphatidylcholine ratio in urine is associated with prostate cancer.
Cancer science.
2021 Oct; 112(10):4292-4302. doi:
10.1111/cas.15093
. [PMID: 34328656] - Rika Ishikawa, Kosuke Saito, Tsuyoshi Matsumura, Koji Arai, Saki Yamauchi, Ryoya Goda, Hidehisa Tachiki, Mitsuhiko Kawabata, Shin-Ichiro Nitta, Akemi Nagao, Takahiro Suga, Hitoshi Uchiyama, Keiko Nakai, Kota Asahina, Mariko Yamaoka, Yoshiro Saito. A multilaboratory validation study of LC/MS biomarker assays for three lysophosphatidylcholines.
Bioanalysis.
2021 Oct; 13(20):1533-1546. doi:
10.4155/bio-2021-0150
. [PMID: 34696608] - Priya Putta, Andrew H Smith, Pinaki Chaudhuri, Rocio Guardia-Wolff, Michael A Rosenbaum, Linda M Graham. Activation of the cytosolic calcium-independent phospholipase A2 β isoform contributes to TRPC6 externalization via release of arachidonic acid.
The Journal of biological chemistry.
2021 10; 297(4):101180. doi:
10.1016/j.jbc.2021.101180
. [PMID: 34509476] - Dhavamani Sugasini, Peng Yang, Dominic Ng, Sumeet A Khetarpal, Cecilia Vitali, Daniel J Rader, Papasani V Subbaiah. Potential role of hepatic lipase in the accretion of docosahexaenoic acid (DHA) by the brain.
Biochimica et biophysica acta. Molecular and cell biology of lipids.
2021 10; 1866(10):159002. doi:
10.1016/j.bbalip.2021.159002
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