2-Pyridineacetic acid (BioDeep_00000797122)

   


代谢物信息卡片


2-(pyridin-2-yl)acetic acid

化学式: C7H7NO2 (137.0477)
中文名称: 2-(吡啶-2-基)乙酸, 2-吡啶基乙酸, 2-吡啶乙酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=NC(=C1)CC(=O)O
InChI: InChI=1S/C7H7NO2/c9-7(10)5-6-3-1-2-4-8-6/h1-4H,5H2,(H,9,10)

描述信息

同义名列表

25 个代谢物同义名

2-(pyridin-2-yl)acetic acid; 2-Pyridinylacetic acid; 2-Pyridineacetic acid; 2-Pyridineacetic acid; (2-pyridinyl)acetic acid; (2-pyridyl)-acetic acid; (pyridin-2-yl)acetic acid; 13Z7401TV3; 2-(2-pyridinyl)acetic acid; 2-(2-pyridyl)acetic acid; 2-(pyridin-2-yl)-acetic acid; 2-(Pyridin-2-yl)aceticacid; 2-pyridin-2-ylacetic acid; 2-Pyridinylacetic acid #; 2-Pyridyl acetic acid D6; 2-pyridyl-acetic acid; 2-pyridylacetic acid; pyridin-2-yl-acetic acid; pyridin-2-ylacetic acid; pyridine-2-acetic acid; pyridine-2-yl-acetic acid; pyridine-acetic acid; Pyridineacetic acid; pyridyl acetic acid; UNII-13Z7401TV3



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

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Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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亚细胞结构定位 关联基因列表


文献列表

  • Krunal Soni, Chandrakant Bhatt, Kanchan Singh, P C Bhuvaneshwari, Anil Jha, Palak Patel, Harilal Patel, Nuggehally R Srinivas. An LC-MS/MS assay for the quantitative determination of 2-pyridyl acetic acid, a major metabolite and key surrogate for betahistine, using low-volume human K2 EDTA plasma. Biomedical chromatography : BMC. 2017 Feb; 31(2):. doi: 10.1002/bmc.3790. [PMID: 27428039]
  • Ganesh Moorthy, Floyd Sallee, Prasad Gabbita, Frank Zemlan, Larry Sallans, Pankaj B Desai. Safety, tolerability and pharmacokinetics of 2-pyridylacetic acid, a major metabolite of betahistine, in a phase 1 dose escalation study in subjects with ADHD. Biopharmaceutics & drug disposition. 2015 Oct; 36(7):429-39. doi: 10.1002/bdd.1955. [PMID: 25904220]
  • Xiangdong Su, Fabienne Pradaux-Caggiano, Nigel Vicker, Mark P Thomas, Heather Halem, Michael D Culler, Barry V L Potter. Adamantyl ethanone pyridyl derivatives: potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1. ChemMedChem. 2011 Sep; 6(9):1616-29. doi: 10.1002/cmdc.201100182. [PMID: 21714097]
  • Javier Sampedro, Brenda Pardo, Cristina Gianzo, Esteban Guitián, Gloria Revilla, Ignacio Zarra. Lack of α-xylosidase activity in Arabidopsis alters xyloglucan composition and results in growth defects. Plant physiology. 2010 Nov; 154(3):1105-15. doi: 10.1104/pp.110.163212. [PMID: 20801759]
  • Ligia Val, Lu Shi Chen, Gustavo Duarte Mendes, Gilberto De Nucci. Comparative bioavailability of betahistine tablet formulations administered in healthy subjects. Arzneimittel-Forschung. 2010; 60(7):440-4. doi: 10.1055/s-0031-1296309. [PMID: 20712134]
  • X Y Chen, D F Zhong, J L Duan, B X Yan. LC-MS-MS analysis of 2-pyridylacetic acid, a major metabolite of betahistine: application to a pharmacokinetic study in healthy volunteers. Xenobiotica; the fate of foreign compounds in biological systems. 2003 Dec; 33(12):1261-71. doi: 10.1080/716689336. [PMID: 14765546]
  • Xiaoyan Chen, Dafang Zhong, Ying Han, Zhiyong Xie. Determination of carbocysteine in human plasma by liquid chromatography/tandem mass spectrometry employing precolumn derivatization. Rapid communications in mass spectrometry : RCM. 2003; 17(3):192-6. doi: 10.1002/rcm.894. [PMID: 12539182]
  • L Botta, E Mira, S Valli, G Zucca, C Benvenuti, A Fossati, E Soto, P Guth, P Valli. Effects of betahistine and of its metabolites on vestibular sensory organs. Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale. 2001 Jun; 21(3 Suppl 66):24-30. doi: NULL. [PMID: 11677836]