Gadoxetate Disodium (BioDeep_00000795786)
代谢物信息卡片
Gadoxetate Disodium
化学式: C23H28GdN3Na2O11 (726.0760268000001)
中文名称: 钆塞酸二钠
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOC1=CC=C(C=C1)CC(CN(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[Gd+3]
InChI: +3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yingying Liang, Fan Xu, Qiuju Mou, Zihua Wang, Chuyin Xiao, Tingwen Zhou, Nianru Zhang, Jing Yang, Hongzhen Wu. A gadoxetic acid-enhanced MRI-based model using LI-RADS v2018 features for preoperatively predicting Ki-67 expression in hepatocellular carcinoma.
BMC medical imaging.
2024 Jan; 24(1):27. doi:
10.1186/s12880-024-01204-9. [PMID: 38273242] - Belle V van Rosmalen, Michele Visentin, Alicia Furumaya, Otto M van Delden, Geert Kazemier, Thomas M van Gulik, Joanne Verheij, Bruno Stieger. Association Between Gadoxetic Acid-Enhanced Magnetic Resonance Imaging, Organic Anion Transporters, and Farnesoid X Receptor in Benign Focal Liver Lesions.
Drug metabolism and disposition: the biological fate of chemicals.
2024 Jan; 52(2):118-125. doi:
10.1124/dmd.123.001492. [PMID: 38050024] - Wen-Yu Zhang, Hao-Yang Sun, Wen-Long Zhang, Rui Feng. Effect of type 2 diabetes on liver images of GD-EOB-DTPA-enhanced MRI during the hepatobiliary phase.
Scientific reports.
2023 01; 13(1):543. doi:
10.1038/s41598-023-27730-0. [PMID: 36631556] - Yingying Liang, Fan Xu, Zihua Wang, Caihong Tan, Nianru Zhang, Xinhua Wei, Xinqing Jiang, Hongzhen Wu. A gadoxetic acid-enhanced MRI-based multivariable model using LI-RADS v2018 and other imaging features for preoperative prediction of macrotrabecular-massive hepatocellular carcinoma.
European journal of radiology.
2022 Aug; 153(?):110356. doi:
10.1016/j.ejrad.2022.110356. [PMID: 35623312] - Hanyu Jiang, Jingwei Wei, Fangfang Fu, Hong Wei, Yun Qin, Ting Duan, Weixia Chen, Kunlin Xie, Jeong Min Lee, Mustafa R Bashir, Meiyun Wang, Bin Song, Jie Tian. Predicting microvascular invasion in hepatocellular carcinoma: A dual-institution study on gadoxetate disodium-enhanced MRI.
Liver international : official journal of the International Association for the Study of the Liver.
2022 05; 42(5):1158-1172. doi:
10.1111/liv.15231. [PMID: 35243749] - Jeong Ah Hwang, Ji Hye Min, Seong Hyun Kim, Seo-Youn Choi, Ji Eun Lee, Ji Yoon Moon. Total Bilirubin Level as a Predictor of Suboptimal Image Quality of the Hepatobiliary Phase of Gadoxetic Acid-Enhanced MRI in Patients with Extrahepatic Bile Duct Cancer.
Korean journal of radiology.
2022 04; 23(4):389-401. doi:
10.3348/kjr.2021.0407. [PMID: 35029076] - Takumi Sugiura, Kenichiro Okumura, Motomitsu Sasaki, Junichi Matsumoto, Takahiro Ogi, Norihide Yoneda, Azusa Kitao, Kazuto Kozaka, Wataru Koda, Satoshi Kobayashi, Toshifumi Gabata. A low albumin level as a risk factor for transient severe motion artifact induced by gadoxetate disodium administration: A retrospective observational study with free-breathing dynamic MRI and an experimental study in rats.
PloS one.
2022; 17(3):e0265588. doi:
10.1371/journal.pone.0265588. [PMID: 35303023] - Wonjeong Yang, Ji Eun Kim, Ho Cheol Choi, Mi Jung Park, Hye Young Choi, Hwa Seon Shin, Jeong Ho Won, Fei Han, Marcel Dominik Nickel, Hyun Chin Cho. T2 mapping in gadoxetic acid-enhanced MRI: utility for predicting decompensation and death in cirrhosis.
European radiology.
2021 Nov; 31(11):8376-8387. doi:
10.1007/s00330-021-07805-0. [PMID: 33782768] - Victoria Sattarova, Mehmet Gencturk, Michael S Lee, Collin M McClelland. Gadoxetate Disodium-Enhanced Imaging of Gradenigo Syndrome in End-Stage Renal Disease.
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society.
2021 Sep; 41(3):e375-e377. doi:
10.1097/wno.0000000000001218. [PMID: 33813531] - Daniel Scotcher, Nicola Melillo, Sirisha Tadimalla, Adam S Darwich, Sabina Ziemian, Kayode Ogungbenro, Gunnar Schütz, Steven Sourbron, Aleksandra Galetin. Physiologically Based Pharmacokinetic Modeling of Transporter-Mediated Hepatic Disposition of Imaging Biomarker Gadoxetate in Rats.
Molecular pharmaceutics.
2021 08; 18(8):2997-3009. doi:
10.1021/acs.molpharmaceut.1c00206. [PMID: 34283621] - Ti-Yung Tseng, Jeng-Hwei Tseng, Bing-Shen Huang, Shen-Yen Lin, Chun-Bing Chen, Yi-Wen Fang, Gigin Lin, Ying-Chieh Lai. Risk of nephrogenic systemic fibrosis in patients with impaired renal function undergoing fixed-dose gadoxetic acid-enhanced magnetic resonance imaging.
Abdominal radiology (New York).
2021 08; 46(8):3995-4001. doi:
10.1007/s00261-021-03045-4. [PMID: 33742216] - T Notake, A Shimizu, K Kubota, T Ikehara, H Hayashi, K Yasukawa, A Kobayashi, A Yamada, Y Fujinaga, Y Soejima. Hepatocellular uptake index obtained with gadoxetate disodium-enhanced magnetic resonance imaging in the assessment future liver remnant function after major hepatectomy for biliary malignancy.
BJS open.
2021 07; 5(4):. doi:
10.1093/bjsopen/zraa048. [PMID: 34254117] - Yanfen Fan, Yixing Yu, Ximing Wang, Mengjie Hu, Chunhong Hu. Radiomic analysis of Gd-EOB-DTPA-enhanced MRI predicts Ki-67 expression in hepatocellular carcinoma.
BMC medical imaging.
2021 06; 21(1):100. doi:
10.1186/s12880-021-00633-0. [PMID: 34130644] - Hanyu Jiang, Bin Song, Yun Qin, Jie Chen, Dong Xiao, Hong Ii Ha, Xijiao Liu, Omobonike Oloruntoba-Sanders, Alaattin Erkanli, Andrew J Muir, Mustafa R Bashir. Diagnosis of LI-RADS M lesions on gadoxetate-enhanced MRI: identifying cholangiocarcinoma-containing tumor with serum markers and imaging features.
European radiology.
2021 Jun; 31(6):3638-3648. doi:
10.1007/s00330-020-07488-z. [PMID: 33245494] - Jae Seok Bae, Jung Hoon Kim, Dong Ho Lee, Jae Hyun Kim, Joon Koo Han. Hepatobiliary phase of gadoxetic acid-enhanced MRI in patients with HCC: prognostic features before resection, ablation, or TACE.
European radiology.
2021 Jun; 31(6):3627-3637. doi:
10.1007/s00330-020-07499-w. [PMID: 33211146] - Hidenori Toyoda, Satoshi Yasuda, Shohei Shiota, Yasuhiro Sone, Atsuyuki Maeda, Yuji Kaneoka, Takashi Kumada, Junko Tanaka. Pretreatment non-hypervascular hypointense nodules on Gd-EOB-DTPA-enhanced MRI as a predictor of hepatocellular carcinoma development after sustained virologic response in HCV infection.
Alimentary pharmacology & therapeutics.
2021 06; 53(12):1309-1316. doi:
10.1111/apt.16382. [PMID: 33896023] - Carlos Arroyo, Jorge Campos, Yunam Cuan-Baltazar, Elena Soto-Vega. Primovist® (Gadotrexate disodium) magnetic resonance use in benign and malignant kidney diagnosis.
Archivos espanoles de urologia.
2021 May; 74(4):411-418. doi:
NULL. [PMID: 33942734] - Michael Weiss, Werner Siegmund. Unusual Distribution Kinetics of Gadoxetate in Healthy Human Subjects Genotyped for OATP1B1: Application of Population Analysis and a Minimal Physiological-Based Pharmacokinetic Model.
Journal of clinical pharmacology.
2021 04; 61(4):506-514. doi:
10.1002/jcph.1762. [PMID: 33084108] - Yanfen Fan, Yixing Yu, Mengjie Hu, Ximing Wang, Mingzhan Du, Lingchuan Guo, Chunhong Hu. Imaging features based on Gd-EOB-DTPA-enhanced MRI for predicting vessels encapsulating tumor clusters (VETC) in patients with hepatocellular carcinoma.
The British journal of radiology.
2021 Mar; 94(1119):20200950. doi:
10.1259/bjr.20200950. [PMID: 33417489] - Sabina Ziemian, Claudia Green, Steven Sourbron, Gregor Jost, Gunnar Schütz, Catherine D G Hines. Ex vivo gadoxetate relaxivities in rat liver tissue and blood at five magnetic field strengths from 1.41 to 7 T.
NMR in biomedicine.
2021 01; 34(1):e4401. doi:
10.1002/nbm.4401. [PMID: 32851735] - Jitka Starekova, Richard J Bruce, Elizabeth A Sadowski, Scott B Reeder. No Cases of Nephrogenic Systemic Fibrosis after Administration of Gadoxetic Acid.
Radiology.
2020 12; 297(3):556-562. doi:
10.1148/radiol.2020200788. [PMID: 32990511] - Matthew S Davenport, Prasad R Shankar. Risk of Nephrogenic Systemic Fibrosis from Gadoxetic Acid in Patients with Severe Kidney Disease.
Radiology.
2020 12; 297(3):563-564. doi:
10.1148/radiol.2020203644. [PMID: 32996871] - Nicola Schieda, Christian B van der Pol, Daniel Walker, Anne K Tsampalieros, Pejman J Maralani, Sungmin Woo, Matthew S Davenport. Adverse Events to the Gadolinium-based Contrast Agent Gadoxetic Acid: Systematic Review and Meta-Analysis.
Radiology.
2020 12; 297(3):565-572. doi:
10.1148/radiol.2020200073. [PMID: 32452732] - Hong Wei, Hanyu Jiang, Xijiao Liu, Yun Qin, Tianying Zheng, Siyun Liu, Xin Zhang, Bin Song. Can LI-RADS imaging features at gadoxetic acid-enhanced MRI predict aggressive features on pathology of single hepatocellular carcinoma?.
European journal of radiology.
2020 Nov; 132(?):109312. doi:
10.1016/j.ejrad.2020.109312. [PMID: 33022551] - Ute Lina Fahlenkamp, Katharina Ziegeler, Lisa Christine Adams, Sarah Maria Böker, Günther Engel, Marcus Richard Makowski. Intracellular accumulation capacity of gadoxetate: initial results for a novel biomarker of liver function.
Scientific reports.
2020 10; 10(1):18104. doi:
10.1038/s41598-020-75145-y. [PMID: 33093649] - Hyewon Oh, Yong Eun Chung, Je Sung You, Chan Gyu Joo, Pan Ki Kim, Joon Seok Lim, Myeong-Jin Kim. Gadolinium retention in rat abdominal organs after administration of gadoxetic acid disodium compared to gadodiamide and gadobutrol.
Magnetic resonance in medicine.
2020 10; 84(4):2124-2132. doi:
10.1002/mrm.28249. [PMID: 32162406] - Seong Woo Kim, Youe Ree Kim, Keum Ha Choi, Eun Young Cho, Ji Soo Song, Ji-Eon Kim, Tae-Hoon Kim, Young Hwan Lee, Kwon-Ha Yoon. Staging of Liver Fibrosis by Means of Semiautomatic Measurement of Liver Surface Nodularity in MRI.
AJR. American journal of roentgenology.
2020 09; 215(3):624-630. doi:
10.2214/ajr.19.22041. [PMID: 32755157] - Shintaro Ichikawa, Utaroh Motosugi, Tatsuya Suzuki, Tatsuya Shimizu, Hiroshi Onishi. Imaging features of hepatic inflammatory pseudotumor: distinction from colorectal liver metastasis using gadoxetate disodium-enhanced magnetic resonance imaging.
Abdominal radiology (New York).
2020 08; 45(8):2400-2408. doi:
10.1007/s00261-020-02575-7. [PMID: 32468212] - Xiaodong Yuan, Su Wang, Wenwei Shi, Yu Cai, Yingxin Chen, Ming Chen, Yanghong Peng, Guokun Ao. Dual Plasma Sampling Method to Determine the Hepatic and Renal Clearance of the 2 Diastereoisomers of Gd-EOB-DTPA.
Investigative radiology.
2020 03; 55(3):168-173. doi:
10.1097/rli.0000000000000622. [PMID: 31917760] - Yuki Mori, Utaroh Motosugi, Tatsuya Shimizu, Shintaro Ichikawa, Marie-Luise Kromrey, Hiroshi Onishi. Predicting Patients With Insufficient Liver Enhancement in the Hepatobiliary Phase Before the Injection of Gadoxetic Acid: A Practical Approach Using the Bayesian Method.
Journal of magnetic resonance imaging : JMRI.
2020 01; 51(1):62-69. doi:
10.1002/jmri.26760. [PMID: 31016840] - Simon Matoori, Johannes M Froehlich, Stefan Breitenstein, Viktoria Pozdniakova, Carolin Reischauer, Orpheus Kolokythas, Dow-Mu Koh, Andreas Gutzeit. Serum albumin, total bilirubin, and patient age are independent confounders of hepatobiliary-phase gadoxetate parenchymal liver enhancement.
European radiology.
2019 Nov; 29(11):5813-5822. doi:
10.1007/s00330-019-06179-8. [PMID: 31020338] - Derek J Erstad, Ian A Ramsay, Veronica Clavijo Jordan, Mozhdeh Sojoodi, Bryan C Fuchs, Kenneth K Tanabe, Peter Caravan, Eric M Gale. Tumor Contrast Enhancement and Whole-Body Elimination of the Manganese-Based Magnetic Resonance Imaging Contrast Agent Mn-PyC3A.
Investigative radiology.
2019 11; 54(11):697-703. doi:
10.1097/rli.0000000000000593. [PMID: 31356382] - Emre Ünal, İlkay Sedakat İdilman, Ali Devrim Karaosmanoğlu, Mustafa Nasuh Özmen, Deniz Akata, Muşturay Karcaaltıncaba. Hyperintensity at fat spared area in steatotic liver on the hepatobiliary phase MRI.
Diagnostic and interventional radiology (Ankara, Turkey).
2019 Nov; 25(6):416-420. doi:
10.5152/dir.2019.18535. [PMID: 31650968] - Shanigarn Thiravit, Paphatsanan Suwanchatree, Peenida Skulratanasak, Phakphoom Thiravit, Voraparee Suvannarerg. Correlation Between Apparent Diffusion Coefficient Values of the Renal Parenchyma and Estimated Glomerular Filtration Rates on 3-T Diffusion-Weighted Echo-Planar Magnetic Resonance Imaging.
Journal of computer assisted tomography.
2019 Sep; 43(5):780-785. doi:
10.1097/rct.0000000000000890. [PMID: 31268879] - Gregor Jost, Thomas Frenzel, Janina Boyken, Laura Schoeckel, Hubertus Pietsch. Gadolinium Presence in the Brain After Administration of the Liver-Specific Gadolinium-Based Contrast Agent Gadoxetate: A Systematic Comparison to Multipurpose Agents in Rats.
Investigative radiology.
2019 08; 54(8):468-474. doi:
10.1097/rli.0000000000000559. [PMID: 30932931] - Menq-Rong Wu, Jong-Kai Hsiao, Hon-Man Liu, Yi-You Huang, Yu-Jui Tseng, Pi-Tai Chou, Te-I Weng, Chung-Yi Yang. In vivo imaging of insulin-secreting human pancreatic ductal cells using MRI reporter gene technique: A feasibility study.
Magnetic resonance in medicine.
2019 08; 82(2):763-774. doi:
10.1002/mrm.27749. [PMID: 30957300] - Ji Eun Kim, Hyun Ok Kim, Kyungsoo Bae, Dae Seob Choi, Dominik Nickel. T1 mapping for liver function evaluation in gadoxetic acid-enhanced MR imaging: comparison of look-locker inversion recovery and B1 inhomogeneity-corrected variable flip angle method.
European radiology.
2019 Jul; 29(7):3584-3594. doi:
10.1007/s00330-018-5947-4. [PMID: 30903328] - Mikael F Forsgren, Markus Karlsson, Olof Dahlqvist Leinhard, Nils Dahlström, Bengt Norén, Thobias Romu, Simone Ignatova, Mattias Ekstedt, Stergios Kechagias, Peter Lundberg, Gunnar Cedersund. Model-inferred mechanisms of liver function from magnetic resonance imaging data: Validation and variation across a clinically relevant cohort.
PLoS computational biology.
2019 06; 15(6):e1007157. doi:
10.1371/journal.pcbi.1007157. [PMID: 31237870] - Weon Jang, Ji Soo Song, Hyo Sung Kwak, Seung Bae Hwang, Mun Young Paek. Intra-individual comparison of conventional and simultaneous multislice-accelerated diffusion-weighted imaging in upper abdominal solid organs: value of ADC normalization using the spleen as a reference organ.
Abdominal radiology (New York).
2019 05; 44(5):1808-1815. doi:
10.1007/s00261-019-01924-5. [PMID: 30737546] - Lara Chehabeddine, Tala Al Saleh, Marwa Baalbaki, Eman Saleh, Samia J Khoury, Salem Hannoun. Cumulative administrations of gadolinium-based contrast agents: risks of accumulation and toxicity of linear vs macrocyclic agents.
Critical reviews in toxicology.
2019 03; 49(3):262-279. doi:
10.1080/10408444.2019.1592109. [PMID: 30942117] - S Keller, J Sedlacik, T Schuler, R Buchert, M Avanesov, R Zenouzi, A W Lohse, H Kooijman, J Fiehler, C Schramm, J Yamamura. Prospective comparison of diffusion-weighted MRI and dynamic Gd-EOB-DTPA-enhanced MRI for detection and staging of hepatic fibrosis in primary sclerosing cholangitis.
European radiology.
2019 Feb; 29(2):818-828. doi:
10.1007/s00330-018-5614-9. [PMID: 30014204] - Tobias Getzin, Faikah Gueler, Björn Hartleben, Marcel Gutberlet, Anja Thorenz, Rongjun Chen, Martin Meier, Jan Hinrich Bräsen, Thorsten Derlin, Dagmar Hartung, Hannah A S Lang, Hermann Haller, Frank Wacker, Song Rong, Katja Hueper. Gd-EOB-DTPA-enhanced MRI for quantitative assessment of liver organ damage after partial hepatic ischaemia reperfusion injury: correlation with histology and serum biomarkers of liver cell injury.
European radiology.
2018 Oct; 28(10):4455-4464. doi:
10.1007/s00330-018-5380-8. [PMID: 29713782] - Dong Kyun Kim, Joon-Il Choi, Moon Hyung Choi, Michael Yong Park, Young Joon Lee, Sung Eun Rha, Seung Eun Jung. Prediction of Posthepatectomy Liver Failure: MRI With Hepatocyte-Specific Contrast Agent Versus Indocyanine Green Clearance Test.
AJR. American journal of roentgenology.
2018 09; 211(3):580-587. doi:
10.2214/ajr.17.19206. [PMID: 29995498] - C Wang, Z C Wang, Y Ding, M S Zeng, S X Rao. [Value of gadoxetate disodium-enhanced magnetic resonance on hepatobiliary phase T1 mapping for predicting liver injury].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology.
2018 Jul; 26(7):530-534. doi:
10.3760/cma.j.issn.1007-3418.2018.07.010. [PMID: 30317777] - Cecilia Besa, Mathilde Wagner, Grace Lo, Sonja Gordic, Manjil Chatterji, Paul Kennedy, Ashley Stueck, Swan Thung, James Babb, Andrew Smith, Bachir Taouli. Detection of liver fibrosis using qualitative and quantitative MR elastography compared to liver surface nodularity measurement, gadoxetic acid uptake, and serum markers.
Journal of magnetic resonance imaging : JMRI.
2018 06; 47(6):1552-1561. doi:
10.1002/jmri.25911. [PMID: 29193508] - Hironao Okubo, Hitoshi Ando, Yushi Sorin, Eisuke Nakadera, Hiroo Fukada, Junichi Morishige, Akihisa Miyazaki, Kenichi Ikejima. Gadoxetic acid-enhanced magnetic resonance imaging to predict paritaprevir-induced hyperbilirubinemia during treatment of hepatitis C.
PloS one.
2018; 13(4):e0196747. doi:
10.1371/journal.pone.0196747. [PMID: 29709031] - Tatsuya Hayashi, Satoshi Saitoh, Kei Fukuzawa, Yoshinori Tsuji, Junji Takahashi, Yusuke Kawamura, Norio Akuta, Masahiro Kobayashi, Kenji Ikeda, Takeshi Fujii, Tosiaki Miyati, Hiromitsu Kumada. Noninvasive Assessment of Advanced Fibrosis Based on Hepatic Volume in Patients with Nonalcoholic Fatty Liver Disease.
Gut and liver.
2017 Sep; 11(5):674-683. doi:
10.5009/gnl16440. [PMID: 28651300] - Michael A Ohliger, Cornelius von Morze, Irene Marco-Rius, Jeremy Gordon, Peder E Z Larson, Robert Bok, Hsin-Yu Chen, John Kurhanewicz, Daniel Vigneron. Combining hyperpolarized 13 C MRI with a liver-specific gadolinium contrast agent for selective assessment of hepatocyte metabolism.
Magnetic resonance in medicine.
2017 06; 77(6):2356-2363. doi:
10.1002/mrm.26296. [PMID: 27298073] - Rama S Ayyala, Lisa A Teot, Jeanette M Perez Rossello. Gaucher disease in the liver on hepatocyte specific contrast agent enhanced MR imaging.
Pediatric radiology.
2017 Apr; 47(4):484-487. doi:
10.1007/s00247-017-3779-z. [PMID: 28144704] - Michael Haimerl, Niklas Verloh, Florian Zeman, Claudia Fellner, Dominik Nickel, Sven A Lang, Andreas Teufel, Christian Stroszczynski, Philipp Wiggermann. Gd-EOB-DTPA-enhanced MRI for evaluation of liver function: Comparison between signal-intensity-based indices and T1 relaxometry.
Scientific reports.
2017 03; 7(?):43347. doi:
10.1038/srep43347. [PMID: 28266528] - Hironao Okubo, Tsuneo Kitamura, Hitoshi Ando, Hiroo Fukada, Yuki Igusa, Shigehiro Kokubu, Akihisa Miyazaki, Akio Fujimura, Shuichiro Shiina, Sumio Watanabe. Gadoxetic Acid-Enhanced MR Imaging Predicts Simeprevir-Induced Hyperbilirubinemia During Hepatitis C Virus Treatment: A Pilot Study.
Journal of clinical pharmacology.
2017 03; 57(3):369-375. doi:
10.1002/jcph.811. [PMID: 27530761] - María P Elizalde-González, Esmeralda García-Díaz, Mario González-Perea, Jürgen Mattusch. Removal of gadolinium-based contrast agents: adsorption on activated carbon.
Environmental science and pollution research international.
2017 Mar; 24(9):8164-8175. doi:
10.1007/s11356-017-8491-x. [PMID: 28144867] - Yu Lu, Pengfei Liu, Peng Fu, Yaodong Chen, Dong Nan, Xiuhua Yang. Comparison of the DWI and Gd-EOB-DTPA-enhanced MRI on assessing the hepatic ischemia and reperfusion injury after partial hepatectomy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2017 Feb; 86(?):118-126. doi:
10.1016/j.biopha.2016.11.123. [PMID: 27951418] - Jeong Hee Yoon, Jeong Min Lee, Eunju Kim, Tomoyuki Okuaki, Joon Koo Han. Quantitative Liver Function Analysis: Volumetric T1 Mapping with Fast Multisection B1 Inhomogeneity Correction in Hepatocyte-specific Contrast-enhanced Liver MR Imaging.
Radiology.
2017 Feb; 282(2):408-417. doi:
10.1148/radiol.2016152800. [PMID: 27697007] - M Kobi, V Paroder, M Flusberg, A M Rozenblit, V Chernyak. Limitations of GD-EOB-DTPA-enhanced MRI: can clinical parameters predict suboptimal hepatobiliary phase?.
Clinical radiology.
2017 Jan; 72(1):55-62. doi:
10.1016/j.crad.2016.10.004. [PMID: 27842889] - A Furlan, O N Close, A A Borhani, Y H Wu, M T Heller. Respiratory-motion artefacts in liver MRI following injection of gadoxetate disodium and gadobenate dimeglumine: an intra-individual comparative study in cirrhotic patients.
Clinical radiology.
2017 Jan; 72(1):93.e1-93.e6. doi:
10.1016/j.crad.2016.08.005. [PMID: 27633725] - Yasuo Takatsu, Satoshi Kobayashi, Tosiaki Miyati, Toshiki Shiozaki. Hepatobiliary phase images using gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid-enhanced MRI as an imaging surrogate for the albumin-bilirubin grading system.
European journal of radiology.
2016 Dec; 85(12):2206-2210. doi:
10.1016/j.ejrad.2016.10.010. [PMID: 27842668] - Jan Endrikat, So Yeon Kim, Toshiaki Sakaguchi, Susan Dohanish, Josy Breuer. Safety of gadoxetate disodium: results from six clinical phase IV studies in 8194 patients.
Acta radiologica (Stockholm, Sweden : 1987).
2016 Nov; 57(11):1326-1333. doi:
10.1177/0284185115588126. [PMID: 26048848] - Srikanth Boddu, Douglas Brylka, Silvina P Dutruel, Pascal Spincemaille, Martin R Prince. Quantitative evaluation of gadoxetate hepatocyte phase homogeneity: potential imaging markers for detection of early cirrhosis.
Clinical imaging.
2016 Sep; 40(5):979-86. doi:
10.1016/j.clinimag.2016.05.004. [PMID: 27288740] - Tomomi Yamada, Atsushi Obata, Yuto Kashiwagi, Takemi Rokugawa, Shuuichi Matsushima, Tadateru Hamada, Hiroshi Watabe, Kohji Abe. Gd-EOB-DTPA-enhanced-MR imaging in the inflammation stage of nonalcoholic steatohepatitis (NASH) in mice.
Magnetic resonance imaging.
2016 Jul; 34(6):724-729. doi:
10.1016/j.mri.2016.03.009. [PMID: 26979540] - Simon Matoori, Johannes M Froehlich, Stefan Breitenstein, Aleksis Doert, Viktoria Pozdniakova, Dow-Mu Koh, Andreas Gutzeit. Age dependence of spleen- and muscle-corrected hepatic signal enhancement on hepatobiliary phase gadoxetate MRI.
European radiology.
2016 Jun; 26(6):1889-94. doi:
10.1007/s00330-015-3965-z. [PMID: 26334505] - Michael Haimerl, Mona Schlabeck, Niklas Verloh, Florian Zeman, Claudia Fellner, Dominik Nickel, Ana Paula Barreiros, Martin Loss, Christian Stroszczynski, Philipp Wiggermann. Volume-assisted estimation of liver function based on Gd-EOB-DTPA-enhanced MR relaxometry.
European radiology.
2016 Apr; 26(4):1125-33. doi:
10.1007/s00330-015-3919-5. [PMID: 26186960] - Nobuhiro Fujita, Akihiro Nishie, Yoshiki Asayama, Kousei Ishigami, Yasuhiro Ushijima, Yukihisa Takayama, Daisuke Okamoto, Koichiro Morita, Ken Shirabe, Kazuhiro Koto, Yuichiro Kubo, Yoshinao Oda, Hiroshi Honda. Significance of the Signal Intensity of Gadoxetic Acid-enhanced MR Imaging for Predicting the Efficacy of Hepatic Arterial Infusion Chemotherapy in Hepatocellular Carcinoma.
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine.
2016; 15(1):111-20. doi:
10.2463/mrms.2015-0012. [PMID: 26346403] - Chikara Ogawa, Yasunori Minami, Masahiro Morita, Teruyo Noda, Soichi Arasawa, Masako Izuta, Atsushi Kubo, Toshihiro Matsunaka, Hiroyuki Tamaki, Mitsushige Shibatoge, Masatoshi Kudo. Prediction of Embolization Area after Conventional Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma Using SYNAPSE VINCENT.
Digestive diseases (Basel, Switzerland).
2016 ; 34(6):696-701. doi:
10.1159/000448859. [PMID: 27750240] - Shuangshuang Xie, Chenhao Liu, Zichuan Yu, Tao Ren, Jiancun Hou, Lihua Chen, Lixiang Huang, Yue Cheng, Qian Ji, Jianzhong Yin, Longjiang Zhang, Wen Shen. One-stop-shop preoperative evaluation for living liver donors with gadoxetic acid disodium-enhanced magnetic resonance imaging: efficiency and additional benefit.
Clinical transplantation.
2015 Dec; 29(12):1164-72. doi:
10.1111/ctr.12646. [PMID: 26448564] - Alexander M McKinney, Rakhee Gawande, Parham Pezeshk, Charles L Truwit, Jeffrey B Rykken. Preliminary experience with intravenous gadoxetate disodium as a craniospinal MR contrast agent.
European journal of radiology.
2015 Dec; 84(12):2539-47. doi:
10.1016/j.ejrad.2015.09.004. [PMID: 26456308] - Chun-Yi Lin, Wei-Chou Chang, Chen-Te Chou, Ran-Chou Chen. Dynamic-contrast-enhanced magnetic resonance imaging of cirrhotic liver parenchyma: A comparison between gadolinium-diethylenetriamine pentaacetic acid and gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid.
Journal of the Chinese Medical Association : JCMA.
2015 Nov; 78(11):666-72. doi:
10.1016/j.jcma.2015.07.005. [PMID: 26341453] - Tomohiro Sato, Tsutomu Tamada, Shigeru Watanabe, Hirotake Nishimura, Akihiko Kanki, Yasufumi Noda, Atsushi Higaki, Akira Yamamoto, Katsuyoshi Ito. Tissue gadolinium deposition in hepatorenally impaired rats exposed to Gd-EOB-DTPA: evaluation with inductively coupled plasma mass spectrometry (ICP-MS).
La Radiologia medica.
2015 Jun; 120(6):557-62. doi:
10.1007/s11547-014-0492-y. [PMID: 25572545] - Thomas Lauenstein, Francisco Ramirez-Garrido, Young Hoon Kim, Sung Eun Rha, Jens Ricke, Sith Phongkitkarun, Joachim Boettcher, Rajan T Gupta, Pornpim Korpraphong, Wiwatana Tanomkiat, Julia Furtner, Peter S Liu, Maren Henry, Jan Endrikat. Nephrogenic systemic fibrosis risk after liver magnetic resonance imaging with gadoxetate disodium in patients with moderate to severe renal impairment: results of a prospective, open-label, multicenter study.
Investigative radiology.
2015 Jun; 50(6):416-22. doi:
10.1097/rli.0000000000000145. [PMID: 25756684] - N K Ramamurthy, B Moosavi, M D F McInnes, T A Flood, N Schieda. Multiparametric MRI of solid renal masses: pearls and pitfalls.
Clinical radiology.
2015 Mar; 70(3):304-16. doi:
10.1016/j.crad.2014.10.006. [PMID: 25472466] - Kyoung Doo Song, Seong Hyun Kim, Jisun Lee, Kyung A Kang, Joungyoun Kim, Heejin Yoo. Half-dose gadoxetic acid-enhanced liver magnetic resonance imaging in patients at risk for nephrogenic systemic fibrosis.
European journal of radiology.
2015 Mar; 84(3):378-383. doi:
10.1016/j.ejrad.2014.12.010. [PMID: 25591579] - Rihyeon Kim, Jeong Min Lee, Ijin Joo, Dong Ho Lee, Sungmin Woo, Joon Koo Han, Byung Ihn Choi. Differentiation of lipid poor angiomyolipoma from hepatocellular carcinoma on gadoxetic acid-enhanced liver MR imaging.
Abdominal imaging.
2015 Mar; 40(3):531-41. doi:
10.1007/s00261-014-0244-4. [PMID: 25231411] - Hersh Chandarana, Tobias Kai Block, Justin Ream, Artem Mikheev, Samuel H Sigal, Ricardo Otazo, Henry Rusinek. Estimating liver perfusion from free-breathing continuously acquired dynamic gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced acquisition with compressed sensing reconstruction.
Investigative radiology.
2015 Feb; 50(2):88-94. doi:
10.1097/rli.0000000000000105. [PMID: 25333309] - Diego Hernando, Shane A Wells, Karl K Vigen, Scott B Reeder. Effect of hepatocyte-specific gadolinium-based contrast agents on hepatic fat-fraction and R2(⁎).
Magnetic resonance imaging.
2015 Jan; 33(1):43-50. doi:
10.1016/j.mri.2014.10.001. [PMID: 25305414] - Nobuhiro Fujita, Akihiro Nishie, Yuichiro Kubo, Yoshiki Asayama, Yasuhiro Ushijima, Yukihisa Takayama, Koichiro Moirta, Ken Shirabe, Shinichi Aishima, Hiroshi Honda. Hepatocellular carcinoma: clinical significance of signal heterogeneity in the hepatobiliary phase of gadoxetic acid-enhanced MR imaging.
European radiology.
2015 Jan; 25(1):211-20. doi:
10.1007/s00330-014-3349-9. [PMID: 25063395] - Nozomu Wada, Kazuhiro Nouso, Kazuya Kariyama, Akiko Wakuta, Masayuki Kishida, Mamoru Nishimura, Toshihiro Higashi. Liver Sarcoidosis with Unique MRI Images Using Gadolinium Ethoxybenzyl Diethylenetriamine Pentaacetic Acid.
Acta medica Okayama.
2015; 69(5):307-11. doi:
10.18926/amo/53677. [PMID: 26490028] - Taro Yamashita, Azusa Kitao, Osamu Matsui, Takehiro Hayashi, Kouki Nio, Mitsumasa Kondo, Naoki Ohno, Tosiaki Miyati, Hikari Okada, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, Yasuni Nakanuma, Hiroyuki Takamura, Tetsuo Ohta, Yasunari Nakamoto, Masakazu Yamamoto, Tadatoshi Takayama, Shigeki Arii, XinWei Wang, Shuichi Kaneko. Gd-EOB-DTPA-enhanced magnetic resonance imaging and alpha-fetoprotein predict prognosis of early-stage hepatocellular carcinoma.
Hepatology (Baltimore, Md.).
2014 Nov; 60(5):1674-85. doi:
10.1002/hep.27093. [PMID: 24700365] - Guido M Kukuk, Stephanie G Schaefer, Rolf Fimmers, Dariusch R Hadizadeh, Samer Ezziddin, Ulrich Spengler, Hans H Schild, Winfried A Willinek. Hepatobiliary magnetic resonance imaging in patients with liver disease: correlation of liver enhancement with biochemical liver function tests.
European radiology.
2014 Oct; 24(10):2482-90. doi:
10.1007/s00330-014-3291-x. [PMID: 25030459] - Stefan Goetschi, Johannes M Froehlich, Natalie C Chuck, Raffaele Curcio, Val M Runge, Gustav Andreisek, Daniel Nanz, Andreas Boss. The protein and contrast agent-specific influence of pathological plasma-protein concentration levels on contrast-enhanced magnetic resonance imaging.
Investigative radiology.
2014 Sep; 49(9):608-19. doi:
10.1097/rli.0000000000000061. [PMID: 24710201] - Junji Ogawa, Azusa Yokota, Takuya Araki, Tohru Aomori, Tomonori Nakamura, Koujirou Yamamoto, Ichiro Koshiishi. Quantitative evaluation of biliary elimination of gadoxetate, a magnetic resonance imaging contrast agent, via geometrical isomer-specific transporting system in rats.
Biopharmaceutics & drug disposition.
2014 Sep; 35(6):362-71. doi:
10.1002/bdd.1907. [PMID: 24947335] - Sung Mo Kim, Suk Hee Heo, Jin Woong Kim, Hyo Soon Lim, Sang Soo Shin, Yong Yeon Jeong, Heoung Keun Kang. Hepatic arterial phase on gadoxetic acid-enhanced liver MR imaging: a randomized comparison of 0.5 mL/s and 1 mL/s injection rates.
Korean journal of radiology.
2014 Sep; 15(5):605-12. doi:
10.3348/kjr.2014.15.5.605. [PMID: 25246821] - Kristina I Ringe, Jan Hinrichs, Elmar M Merkle, Tobias J Weismüller, Frank Wacker, Bernhard C Meyer. Gadoxetate disodium in patients with primary sclerosing cholangitis: an analysis of hepatobiliary contrast excretion.
Journal of magnetic resonance imaging : JMRI.
2014 Jul; 40(1):106-12. doi:
10.1002/jmri.24381. [PMID: 24923477] - B-B Chen, C-Y Hsu, C-W Yu, J-H Kao, H-S Lee, P-C Liang, S-Y Wei, R-M Hwang, T T-F Shih. Hepatic necro-inflammation and elevated liver enzymes: evaluation with MRI perfusion imaging with gadoxetic acid in chronic hepatitis patients.
Clinical radiology.
2014 May; 69(5):473-80. doi:
10.1016/j.crad.2013.12.003. [PMID: 24556468] - Emina Talakic, Jürgen Steiner, Peter Kalmar, Andre Lutfi, Franz Quehenberger, Ursula Reiter, Michael Fuchsjäger, Helmut Schöllnast. Gd-EOB-DTPA enhanced MRI of the liver: correlation of relative hepatic enhancement, relative renal enhancement, and liver to kidneys enhancement ratio with serum hepatic enzyme levels and eGFR.
European journal of radiology.
2014 Apr; 83(4):607-11. doi:
10.1016/j.ejrad.2013.12.010. [PMID: 24380639] - Jia Jia, Dorothee Puls, Stefan Oswald, Gabriele Jedlitschky, Jens P Kühn, Werner Weitschies, Norbert Hosten, Werner Siegmund, Markus Keiser. Characterization of the intestinal and hepatic uptake/efflux transport of the magnetic resonance imaging contrast agent gadolinium-ethoxylbenzyl-diethylenetriamine-pentaacetic acid.
Investigative radiology.
2014 Feb; 49(2):78-86. doi:
10.1097/rli.0b013e3182a70043. [PMID: 24056116] - Shintaro Ichikawa, Tomoaki Ichikawa, Utaroh Motosugi, Katsuhiro Sano, Hiroyuki Morisaka, Nobuyuki Enomoto, Masanori Matsuda, Hideki Fujii, Tsutomu Araki. Presence of a hypovascular hepatic nodule showing hypointensity on hepatocyte-phase image is a risk factor for hypervascular hepatocellular carcinoma.
Journal of magnetic resonance imaging : JMRI.
2014 Feb; 39(2):293-7. doi:
10.1002/jmri.24164. [PMID: 23633285] - Ya-Wen Chen, Meng-Yuan Tsai, Huay-Ben Pan, Hui-Hwa Tseng, Yu-Ting Hung, Chen-Pin Chou. Gadoxetic acid-enhanced MRI and sonoelastography: non-invasive assessments of chemoprevention of liver fibrosis in thioacetamide-induced rats with Sho-Saiko-To.
PloS one.
2014; 9(12):e114756. doi:
10.1371/journal.pone.0114756. [PMID: 25490034] - Kazuhiro Saito, Joseph Ledsam, Steven Sourbron, Tsuyoshi Hashimoto, Yoichi Araki, Soichi Akata, Koichi Tokuuye. Measuring hepatic functional reserve using low temporal resolution Gd-EOB-DTPA dynamic contrast-enhanced MRI: a preliminary study comparing galactosyl human serum albumin scintigraphy with indocyanine green retention.
European radiology.
2014 Jan; 24(1):112-9. doi:
10.1007/s00330-013-2983-y. [PMID: 23949726] - Jose L Ulloa, Simone Stahl, James Yates, Neil Woodhouse, J Gerry Kenna, Huw B Jones, John C Waterton, Paul D Hockings. Assessment of gadoxetate DCE-MRI as a biomarker of hepatobiliary transporter inhibition.
NMR in biomedicine.
2013 Oct; 26(10):1258-70. doi:
10.1002/nbm.2946. [PMID: 23564602] - R Joshua Dym, Victoria Chernyak, Alla M Rozenblit. MR imaging of renal collecting system with gadoxetate disodium: feasibility for MR urography.
Journal of magnetic resonance imaging : JMRI.
2013 Oct; 38(4):816-23. doi:
10.1002/jmri.24059. [PMID: 23408536] - Ji Yeon Kim, Seung Soo Lee, Jae Ho Byun, So Yeon Kim, Seong Ho Park, Young Moon Shin, Moon-Gyu Lee. Biologic factors affecting HCC conspicuity in hepatobiliary phase imaging with liver-specific contrast agents.
AJR. American journal of roentgenology.
2013 Aug; 201(2):322-31. doi:
10.2214/ajr.12.9478. [PMID: 23883212] - Tsutomu Tamada, Katsuyoshi Ito, Akira Yamamoto, Kazuya Yasokawa, Atsushi Higaki, Akihiko Kanki, Tomohiro Sato, Daigo Taniomoto, Hiroki Higashi. Simple Method for evaluating the degree of liver parenchymal enhancement in the hepatobiliary phase of gadoxetic acid-enhanced magnetic resonance imaging.
Journal of magnetic resonance imaging : JMRI.
2013 May; 37(5):1115-21. doi:
10.1002/jmri.23912. [PMID: 23148041] - Utaroh Motosugi, Tomoaki Ichikawa, Tsuyota Koshiishi, Katsuhiro Sano, Hiroyuki Morisaka, Shintaro Ichikawa, Nobuyuki Enomoto, Masanori Matsuda, Hideki Fujii, Tsutomu Araki. Liver stiffness measured by magnetic resonance elastography as a risk factor for hepatocellular carcinoma: a preliminary case-control study.
European radiology.
2013 Jan; 23(1):156-62. doi:
10.1007/s00330-012-2571-6. [PMID: 22814828] - Azusa Kitao, Osamu Matsui, Norihide Yoneda, Kazuto Kozaka, Satoshi Kobayashi, Wataru Koda, Toshifumi Gabata, Tatsuya Yamashita, Shuichi Kaneko, Yasuni Nakanuma, Ryuichi Kita, Shigeki Arii. Hypervascular hepatocellular carcinoma: correlation between biologic features and signal intensity on gadoxetic acid-enhanced MR images.
Radiology.
2012 Dec; 265(3):780-9. doi:
10.1148/radiol.12120226. [PMID: 23175543] - Shigeyoshi Saito, Yuki Moriyama, Shuichiro Kobayashi, Ryota Ogihara, Daichi Koto, Akihiro Kitamura, Taro Matsushita, Motoko Nishiura, Kenya Murase. Assessment of liver function in thioacetamide-induced rat acute liver injury using an empirical mathematical model and dynamic contrast-enhanced MRI with Gd-EOB-DTPA.
Journal of magnetic resonance imaging : JMRI.
2012 Dec; 36(6):1483-9. doi:
10.1002/jmri.23726. [PMID: 22711439] - Rajan T Gupta, Daniele Marin, Daniel T Boll, Daniela B Husarik, Drew E Davis, Sebastian Feuerlein, Elmar M Merkle. Hepatic hemangiomas: difference in enhancement pattern on 3T MR imaging with gadobenate dimeglumine versus gadoxetate disodium.
European journal of radiology.
2012 Oct; 81(10):2457-62. doi:
10.1016/j.ejrad.2011.10.014. [PMID: 22138122] - Ali Nassif, Jia Jia, Markus Keiser, Stefan Oswald, Christiane Modess, Stefan Nagel, Werner Weitschies, Norbert Hosten, Werner Siegmund, Jens-Peter Kühn. Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.
Radiology.
2012 Sep; 264(3):741-50. doi:
10.1148/radiol.12112061. [PMID: 22771883] - Steven Sourbron, Wieland H Sommer, Maximilian F Reiser, Christoph J Zech. Combined quantification of liver perfusion and function with dynamic gadoxetic acid-enhanced MR imaging.
Radiology.
2012 Jun; 263(3):874-83. doi:
10.1148/radiol.12110337. [PMID: 22623698] - Akihiro Nishie, Yasuhiro Ushijima, Tsuyoshi Tajima, Yoshiki Asayama, Kousei Ishigami, Daisuke Kakihara, Tomohiro Nakayama, Yukihisa Takayama, Daisuke Okamoto, Koichiro Abe, Makoto Obara, Kengo Yoshimitsu, Hiroshi Honda. Quantitative analysis of liver function using superparamagnetic iron oxide- and Gd-EOB-DTPA-enhanced MRI: comparison with Technetium-99m galactosyl serum albumin scintigraphy.
European journal of radiology.
2012 Jun; 81(6):1100-4. doi:
10.1016/j.ejrad.2011.02.053. [PMID: 21435811]