butyl(3-carboxypropyl)nitrosamine (BioDeep_00000794789)
代谢物信息卡片
化学式: C8H16N2O3 (188.11608660000002)
中文名称: 4-(N-丁基-N-亚硝胺基)丁酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCN(CCCC(=O)O)N=O
InChI: InChI=1S/C8H16N2O3/c1-2-3-6-10(9-13)7-4-5-8(11)12/h2-7H2,1H3,(H,11,12)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Takashi Murai, Yukio Mori, Kenjiro Tatematsu, Akihiro Koide, Akihiro Hagiwara, Susumu Makino, Satoru Mori, Hideki Wanibuchi, Shoji Fukushima. Differences in susceptibility to N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis between SD/gShi rats with spontaneous hypospermatogenesis and SD/cShi rats with spontaneous hydronephrosis.
Cancer science.
2005 Oct; 96(10):637-44. doi:
10.1111/j.1349-7006.2005.00108.x. [PMID: 16232194] - Y Mori, A Koide, K Fuwa, H Wanibuchi, S Fukushima. Lack of change in the levels of liver and kidney cytochrome P-450 isozymes in p53+/- knockout mice treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Mutagenesis.
2001 Sep; 16(5):377-83. doi:
10.1093/mutage/16.5.377. [PMID: 11507236] - C Janzowski, R Landsiedel, P Gölzer, G Eisenbrand. Mitochondrial formation of beta-oxopropyl metabolites from bladder carcinogenic omega-carboxyalkylnitrosamines.
Chemico-biological interactions.
1994 Jan; 90(1):23-33. doi:
10.1016/0009-2797(94)90108-2. [PMID: 8131217] - C C Irving. Oxidation of N-butyl-N-(3-formylpropyl)nitrosamine to N-butyl-N-(3-carboxypropyl)nitrosamine in rat liver and inhibition by disulfiram.
Carcinogenesis.
1988 Nov; 9(11):2109-12. doi:
10.1093/carcin/9.11.2109. [PMID: 3180345] - M Takahashi, S Shumiya, A Maekawa, Y Hayashi, S Nagase. High susceptibility of an analbuminemic congenic strain of rats with an F344 genetic background to induced bladder cancer and its possible mechanism.
Japanese journal of cancer research : Gann.
1988 Jun; 79(6):705-9. doi:
10.1111/j.1349-7006.1988.tb02226.x. [PMID: 3137197] - C C Irving, D S Daniel. Influence of disulfiram on the metabolism of the urinary bladder carcinogen N-butyl-N-(4-hydroxybutyl)nitrosamine in the rat.
Carcinogenesis.
1987 Sep; 8(9):1309-15. doi:
10.1093/carcin/8.9.1309. [PMID: 3113755] - L Airoldi, M Bonfanti, C Magagnotti, R Fanelli. Development of an experimental model for studying bladder carcinogen metabolism using the isolated rat urinary bladder.
Cancer research.
1987 Jul; 47(14):3697-700. doi:
. [PMID: 3594434] - Y Homma, S Ozono, C B Wallenmark, R Oyasu. Agglutination by concanavalin A of urothelial cells of heterotropically transplanted rat urinary bladders: effect of bladder carcinogens and urine.
Carcinogenesis.
1985 Jul; 6(7):1059-61. doi:
10.1093/carcin/6.7.1059. [PMID: 4017172] - S Wada, Y Funae, S Imaoka, M Kawamura, Y Kinoshita, T Sugimoto, S Nishio, T Kishimoto, M Maekawa. Rapid assay of N-butyl-N-(3-carboxypropyl)nitrosamine in rat organs and urine by high-performance liquid chromatography after derivatization.
Japanese journal of cancer research : Gann.
1985 Mar; 76(3):192-6. doi:
NULL. [PMID: 3922837] - L Airoldi, C Spagone, A Macri, R Fanelli. Experimental model for evaluating animal exposure to endogenous N-nitrosodi-n-butylamine by measuring its urinary metabolites N-butyl-N-(4-hydroxybutyl)-nitrosamine and N-butyl-N-(3-carboxypropyl)nitrosamine.
IARC scientific publications.
1984; ?(57):237-40. doi:
. [PMID: 6533013] - L Airoldi, C Spagone, M Bonfanti, C Pantarotto, R Fanelli. Rapid method for quantitative analysis of N,N-dibutylnitrosamine, N-butyl-N-(4-hydroxybutyl)nitrosamine and N-butyl-N-(3-carboxypropyl)-nitrosamine in rat urine by gas chromatography--thermal energy analysis.
Journal of chromatography.
1983 Sep; 276(2):402-7. doi:
10.1016/s0378-4347(00)85107-5. [PMID: 6630388] - E Suzuki, M Mochizuki, M Okada. Relationship of urinary N-butyl-N-(3-carboxypropyl)nitrosamine to susceptibility of animals to bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Gan.
1983 Jun; 74(3):360-4. doi:
NULL. [PMID: 6884694]