Murabutide (BioDeep_00000794776)
代谢物信息卡片
化学式: C23H40N4O11 (548.269345)
中文名称: 莫拉布胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCOC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C
InChI: InChI=1S/C23H40N4O11/c1-5-6-9-36-22(34)14(7-8-16(24)30)27-20(32)11(2)25-21(33)12(3)37-19-17(26-13(4)29)23(35)38-15(10-28)18(19)31/h11-12,14-15,17-19,23,28,31,35H,5-10H2,1-4H3,(H2,24,30)(H,25,33)(H,26,29)(H,27,32)
描述信息
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D044966 - Anti-Retroviral Agents
D007155 - Immunologic Factors
同义名列表
2 个代谢物同义名
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Riyasat Ali, Sudhir Kumar, Raza Ali Naqvi, Ishfaq Ahmed Sheikh, D N Rao. Multiple antigen peptide consisting of B- and T-cell epitopes of F1 antigen of Y. pestis showed enhanced humoral and mucosal immune response in different strains of mice.
International immunopharmacology.
2013 Jan; 15(1):97-105. doi:
10.1016/j.intimp.2012.10.029. [PMID: 23174507] - Xavier De La Tribonniere, Yves Mouton, Vincent Vidal, Edith Darcissac, Daouda Sissoko, Clothilde Fontier, Youcef Douadi, Jo lle Dewulf, Corinne Amiel, George M Bahr. A phase I study of a six-week cycle of immunotherapy with Murabutide in HIV-1 patients naive to antiretrovirals.
Medical science monitor : international medical journal of experimental and clinical research.
2003 Jun; 9(6):PI43-50. doi:
NULL. [PMID: 12824957] - Corinne Amiel, Xavier De La Tribonnière, Vincent Vidal, Edith Darcissac, Yves Mouton, George M Bahr. Clinical tolerance and immunologic effects after single or repeated administrations of the synthetic immunomodulator murabutide in HIV-1-infected patients.
Journal of acquired immune deficiency syndromes (1999).
2002 Jul; 30(3):294-305. doi:
10.1097/00126334-200207010-00005. [PMID: 12131566] - E C Darcissac, V Vidal, M Guillaume, J J Thebault, G M Bahr. Clinical tolerance and profile of cytokine induction in healthy volunteers following the simultaneous administration of ifn-alpha and the synthetic immunomodulator murabutide.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
2001 Sep; 21(9):655-61. doi:
10.1089/107999001753124381. [PMID: 11576459] - G M Bahr, E C Darcissac, N Castéran, C Amiel, C Cocude, M J Truong, J Dewulf, A Capron, Y Mouton. Selective regulation of human immunodeficiency virus-infected CD4(+) lymphocytes by a synthetic immunomodulator leads to potent virus suppression in vitro and in hu-PBL-SCID mice.
Journal of virology.
2001 Aug; 75(15):6941-52. doi:
10.1128/jvi.75.15.6941-6952.2001. [PMID: 11435574] - G M Bahr, P R Pouillart, L A Chedid. Enhancement in vivo of the antiinflammatory and antitumor activities of type I interferon by association with the synthetic immunomodulator murabutide.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
1996 Apr; 16(4):297-306. doi:
10.1089/jir.1996.16.297. [PMID: 9162523] - G M Bahr, E Darcissac, D Bevec, P Dukor, L Chedid. Immunopharmacological activities and clinical development of muramyl peptides with particular emphasis on murabutide.
International journal of immunopharmacology.
1995 Feb; 17(2):117-31. doi:
10.1016/0192-0561(94)00094-5. [PMID: 7544767] - M A Parant, P Pouillart, C Le Contel, F J Parant, L A Chedid, G M Bahr. Selective modulation of lipopolysaccharide-induced death and cytokine production by various muramyl peptides.
Infection and immunity.
1995 Jan; 63(1):110-5. doi:
10.1128/iai.63.1.110-115.1995. [PMID: 7806345] - D L Auci, J A Carucci, S M Chice, M C Smith, P Dukor, H G Durkin. Control of IgE responses. 4. Isotype-specific suppression of peak BPO-specific IgE antibody-forming cell responses and of BPO-specific IgE in serum by muramyldipeptide or murabutide after administration to mice by gavage.
International archives of allergy and immunology.
1993; 101(2):167-76. doi:
10.1159/000236515. [PMID: 8508053] - M Parant, F Parant, M A Vinit, C Jupin, Y Noso, L Chedid. Priming effect of muramyl peptides for induction by lipopolysaccharide of tumor necrosis factor production in mice.
Journal of leukocyte biology.
1990 Feb; 47(2):164-9. doi:
10.1002/jlb.47.2.164. [PMID: 2303750] - M J Odean, C M Frane, M Van derVieren, M A Tomai, A G Johnson. Involvement of gamma interferon in antibody enhancement by adjuvants.
Infection and immunity.
1990 Feb; 58(2):427-32. doi:
10.1128/iai.58.2.427-432.1990. [PMID: 2105274] - G Riveau, M Parant, C Damais, F Parant, L Chedid. Dissociation between muramyl dipeptide-induced fever and changes in plasma metal levels.
The American journal of physiology.
1986 Apr; 250(4 Pt 1):C572-7. doi:
10.1152/ajpcell.1986.250.4.c572. [PMID: 3963170] - M Parant, G Riveau, F Parant, L Chedid. Inhibition of endogenous pyrogen-induced fever by a muramyl dipeptide derivative.
The American journal of physiology.
1984 Sep; 247(3 Pt 1):C169-74. doi:
10.1152/ajpcell.1984.247.3.c169. [PMID: 6476105] - A Galelli, L Chedid. Modulation of myelopoiesis in vivo by synthetic adjuvant-active muramyl peptides: induction of colony-stimulating activity and stimulation of stem cell proliferation.
Infection and immunity.
1983 Dec; 42(3):1081-5. doi:
10.1128/iai.42.3.1081-1085.1983. [PMID: 6605930] - K P McAdam, N T Foss, C Garcia, R DeLellis, L Chedid, R J Rees, S M Wolff. Amyloidosis and the serum amyloid A protein response to muramyl dipeptide analogs and different mycobacterial species.
Infection and immunity.
1983 Mar; 39(3):1147-54. doi:
10.1128/iai.39.3.1147-1154.1983. [PMID: 6601620]