Flomoxef (BioDeep_00000793253)

   


代谢物信息卡片


Flomoxef

化学式: C15H18F2N6O7S2 (496.0646422)
中文名称: 氟氧头孢
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1(C2N(C1=O)C(=C(CO2)CSC3=NN=NN3CCO)C(=O)O)NC(=O)CSC(F)F
InChI: InChI=1S/C15H18F2N6O7S2/c1-29-15(18-8(25)6-31-13(16)17)11(28)23-9(10(26)27)7(4-30-12(15)23)5-32-14-19-20-21-22(14)2-3-24/h12-13,24H,2-6H2,1H3,(H,18,25)(H,26,27)/t12-,15+/m1/s1

描述信息

J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DC - Second-generation cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

同义名列表

1 个代谢物同义名

Flomoxef



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Toshiaki Komatsu, Satomi Tsumuraya, Yoko Takayama, Takashi Kaizu, Mikiko Okamoto, Hiroshi Tajima, Nobuyuki Nishizawa, Hidefumi Kubo, Yusuke Kumamoto, Hirotsugu Okamoto, Hideaki Hanaki, Koichiro Atsuda. Population Pharmacokinetic-Pharmacodynamic Target Attainment Analysis of Flomoxef in the Serum and Liver Tissue of Patients Undergoing Hepatic Resection. Antimicrobial agents and chemotherapy. 2022 04; 66(4):e0230321. doi: 10.1128/aac.02303-21. [PMID: 35306834]
  • Kogenta Nakamura, Kazuro Ikawa, Genya Nishikawa, Ikuo Kobayashi, Motoi Tobiume, Miho Sugie, Hiroyuki Muramatsu, Shingo Morinaga, Keishi Kajikawa, Masahito Watanabe, Kent Kanao, Tetsushu Onita, Norifumi Morikawa. Clinical pharmacokinetics of flomoxef in prostate tissue and dosing considerations for prostatitis based on site-specific pharmacodynamic target attainment. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2020 Feb; 26(2):236-241. doi: 10.1016/j.jiac.2019.08.019. [PMID: 31822449]
  • Akiyoshi Horie, Akiyoshi Nariai, Fumihide Katou, Yasuhiro Abe, Yuya Saito, Daisuke Koike, Tomohiro Hirade, Tomoko Ito, Miho Wakuri, Aiko Fukuma. Increased community-acquired upper urinary tract infections caused by extended-spectrum beta-lactamase-producing Escherichia coli in children and the efficacy of flomoxef and cefmetazole. Clinical and experimental nephrology. 2019 Nov; 23(11):1306-1314. doi: 10.1007/s10157-019-01775-w. [PMID: 31428892]
  • Jen-Jia Yang, Jann-Tay Wang, Aristine Cheng, Yu-Chung Chuang, Wang-Huei Sheng. Impact of broad-spectrum antimicrobial treatment on the ecology of intestinal flora. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi. 2018 Oct; 51(5):681-687. doi: 10.1016/j.jmii.2016.12.009. [PMID: 28693929]
  • Tetsuya Masada, Toshihiro Tanaka, Hiroshi Sakaguchi, Masahiro Nakagomi, Yuko Miura, Teruyuki Hidaka, Yozo Sato, Takeshi Sato, Masayoshi Inoue, Kinya Furuich, Hideyuki Nishiofuku, Kimihiko Kichikawa. Coils versus gelatin particles with or without intraarterial antibiotics for partial splenic embolization: a comparative evaluation. Journal of vascular and interventional radiology : JVIR. 2014 Jun; 25(6):852-8. doi: 10.1016/j.jvir.2013.12.563. [PMID: 24534093]
  • Sotaro Sadahiro, Toshiyuki Suzuki, Akira Tanaka, Kazutake Okada, Hiroko Kamata, Toru Ozaki, Yasuhiro Koga. Comparison between oral antibiotics and probiotics as bowel preparation for elective colon cancer surgery to prevent infection: prospective randomized trial. Surgery. 2014 Mar; 155(3):493-503. doi: 10.1016/j.surg.2013.06.002. [PMID: 24524389]
  • Oxana Yu Kravtsova, Sergey A Paramonov, Natalya I Vasilevich, Denis N Kazyulkin, Ekaterina Vlasova, Michael Engsig. Determination of flomoxef in human plasma by liquid chromatography/electrospray ionization tandem mass spectrometry. Biomedical chromatography : BMC. 2013 Dec; 27(12):1609-14. doi: 10.1002/bmc.2968. [PMID: 23780743]
  • Akinobu Ito, Yumiko Matsuo Tatsumi, Toshihiro Wajima, Rio Nakamura, Masakatsu Tsuji. Evaluation of antibacterial activities of flomoxef against ESBL producing Enterobacteriaceae analyzed by Monte Carlo simulation. The Japanese journal of antibiotics. 2013 Apr; 66(2):71-86. doi: NULL. [PMID: 23951726]
  • Kenichiro Yaita, Ichiro Sameshima, Hideaki Takeyama, Shinpei Matsuyama, Chie Nagahara, Ryo Hashiguchi, Yukiko Moronaga, Nami Tottori, Masanari Komatsu, Yusuke Oshiro, Yukihiro Yamaguchi. Liver abscess caused by multidrug-resistant Pseudomonas aeruginosa treated with colistin; a case report and review of the literature. Internal medicine (Tokyo, Japan). 2013; 52(12):1407-12. doi: 10.2169/internalmedicine.52.9296. [PMID: 23774557]
  • Chih-Chao Yang, Shau-Hsuan Li, Feng-Rong Chuang, Chih-Hung Chen, Chih-Hsiung Lee, Jin-Bor Chen, Chien-Hsing Wu, Chien-Te Lee. Discrepancy between effects of carbapenems and flomoxef in treating nosocomial hemodialysis access-related bacteremia secondary to extended spectrum beta-lactamase producing Klebsiella pneumoniae in patients on maintenance hemodialysis. BMC infectious diseases. 2012 Sep; 12(?):206. doi: 10.1186/1471-2334-12-206. [PMID: 22947300]
  • Po-Wei Huang, Tai-Lung Cha, Huang-Ching Chang, Shou-Hung Tang. Target lesions in the bladder from emphysematous cystitis. Kidney international. 2010 Aug; 78(3):325. doi: 10.1038/ki.2010.153. [PMID: 20631736]
  • Kazuro Ikawa, Norifumi Morikawa, Kayo Ikeda, Hiroki Ohge, Taijiro Sueda. Development of breakpoints of cephems for intraabdominal infections based on pharmacokinetics and pharmacodynamics in the peritoneal fluid of patients. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2008 Apr; 14(2):141-6. doi: 10.1007/s10156-008-0598-z. [PMID: 18622678]
  • Zenichi Masuda, Yuji Kurosaki, Kozo Ishino, Keita Yamauchi, Shunji Sano. Pharmacokinetic analysis of flomoxef in children undergoing cardiopulmonary bypass and modified ultrafiltration. General thoracic and cardiovascular surgery. 2008 Apr; 56(4):163-9. doi: 10.1007/s11748-007-0208-5. [PMID: 18401677]
  • Kuo-Chen Cheng, Yin-Ching Chuang, Lii-Tzu Wu, Guan-Cheng Huang, Wen-Liang Yu. Clinical experiences of the infections caused by extended-spectrum beta-lactamase-producing Serratia marcescens at a medical center in Taiwan. Japanese journal of infectious diseases. 2006 Jun; 59(3):147-52. doi: NULL. [PMID: 16785693]
  • Hiroaki Tsumura, Eiso Hiyama, Takashi Kodama, Taijiro Sueda, Takashi Yokoyama. Relevance of antimicrobial agent-induced endotoxin release from in vitro cultured Escherichia coli and in vivo experimental infection with Gram-negative bacilli. International journal of antimicrobial agents. 2003 May; 21(5):463-70. doi: 10.1016/s0924-8579(03)00037-2. [PMID: 12727081]
  • Toshihiro Kitahashi, Itaru Furuta. Determination of antibacterial flomoxef in serum by capillary electrophoresis. Journal of chromatographic science. 2003 Apr; 41(4):173-6. doi: 10.1093/chromsci/41.4.173. [PMID: 12803802]
  • Nagao Shinagawa, Noboru Yamanaka, Kenji Suzuki, Hideyuki Kawauchi, Makoto Oda, Koji Yajin, Yoichi Ishizuka, Yuichi Kurono, Shigetomi Iwai, Takasi Yokoyama, Hiromitsu Takeyama. [A questionnaire survey on the theory of postoperative infection prophylaxis in otorhinolaryngology]. The Japanese journal of antibiotics. 2003 Feb; 56(1):15-26. doi: NULL. [PMID: 12723395]
  • Toshihiro Hamada, Eisaku Ueta, Hiroyuki Kodama, Tokio Osaki. The excretion of cephem antibiotics into saliva is inversely associated with their plasma protein-binding activities. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 2002 Feb; 31(2):109-16. doi: 10.1046/j.0904-2512.2001.00015.x. [PMID: 11896833]
  • S Taniuchi, M Masuda, A Yamamoto, M Hasui, S Tsuji, H Takahashi, Y Kobayashi. Two cases of autoimmune neutropenia possibly induced by beta-lactam antibiotics in infants. Journal of pediatric hematology/oncology. 2000 Nov; 22(6):533-8. doi: 10.1097/00043426-200011000-00013. [PMID: 11132223]
  • T Kuriyama, K Nakagawa, Y Saiki, E Yamamoto. [A case of severe odontogenic infection with allergic skin reaction for beta-lactam antibiotics]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 1997 May; 71(5):459-63. doi: 10.11150/kansenshogakuzasshi1970.71.459. [PMID: 9209128]
  • M Yamamoto, M Jimbo, M Ide, N Tanaka, Y Umebara, S Hagiwara. Perioperative antimicrobial prophylaxis in neurosurgery: clinical trial of systemic flomoxef administration and saline containing gentamicin for irrigation. Neurologia medico-chirurgica. 1996 Jun; 36(6):370-6. doi: 10.2176/nmc.36.370. [PMID: 8700313]
  • T Toyoguchi, Y Nakagawa. [Nephrotoxicity and drug interaction of vancomycin (2)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 1996 May; 107(5):225-35. doi: 10.1254/fpj.107.225. [PMID: 8690304]
  • H H Igawa, T Sugihara, T Yoshida, K Kawashima, T Ohura. Penetration of flomoxef into human maxillary and mandibular bones. Scandinavian journal of plastic and reconstructive surgery and hand surgery. 1995 Sep; 29(3):259-62. doi: 10.3109/02844319509050136. [PMID: 8539570]
  • H Matsumoto, M Yamashita, Y Iguro, T Miyazaki, A Taira. [Postoperative infections in cardiovascular surgery: what is an appropriate prophylactic administration of antibiotics?]. Kyobu geka. The Japanese journal of thoracic surgery. 1995 May; 48(5):375-9. doi: NULL. [PMID: 7745860]
  • F Itoh, K Sato, T Harauchi, M Hirata, Y Mizushima. [Modification of vancomycin nephrotoxicity by other antibiotics in rats]. The Japanese journal of antibiotics. 1995 Mar; 48(3):380-8. doi: . [PMID: 7752451]
  • K Kono, S Takeda, I Tatara, K Arakawa. In vitro activities of arbekacin, alone and in combination, against methicillin-resistant Staphylococcus aureus. The Japanese journal of antibiotics. 1994 Jun; 47(6):710-9. doi: NULL. [PMID: 8072179]
  • T Motohiro, T Maruoka, K Nagai, S Oki, N Tsumura, H Sasaki, M Aramaki, T Koga, Y Sakata, K Tominaga. [Laboratory and clinical studies on flomoxef in neonates and premature infants]. The Japanese journal of antibiotics. 1993 Jul; 46(7):547-67. doi: NULL. [PMID: 8371491]
  • R Fujii, K Fujita, K Murono, M Saijo, F Kakuya, H Yoshioka, S Maruyama, H Sakata, A Hiramoto, F Inyaku. [Pharmacokinetics and clinical studies on flomoxef in neonates and premature infants. A study of flomoxef in the perinatal collaboration research group]. The Japanese journal of antibiotics. 1993 Jul; 46(7):518-38. doi: NULL. [PMID: 8371489]
  • S Matsuda, H Hirayama, K Oh, K Tamate, K Sengoku, M Ishikawa, T Shimizu, H Haga, T Hasegawa, H Takada. [Pharmacokinetic and clinical studies of flomoxef in the perinatal period]. The Japanese journal of antibiotics. 1993 Jul; 46(7):568-76. doi: NULL. [PMID: 8371492]
  • F Sasagawa, T Nakano, Y Mito, O Sekine. [Pharmacokinetics of flomoxef in children undergoing chronic hemodialysis]. The Japanese journal of antibiotics. 1993 Jul; 46(7):511-7. doi: NULL. [PMID: 8371488]
  • Y Ito, H Tokuyama, S Yamada, H Komeda, Y Takahashi, M Okano, A Saitoh, T Deguchi, M Kanematsu, Y Kawada. [A study of methicillin-resistant Staphylococcus aureus (MRSA) infection in urological field]. Nihon Hinyokika Gakkai zasshi. The japanese journal of urology. 1993 Mar; 84(3):514-20. doi: 10.5980/jpnjurol1989.84.514. [PMID: 8515639]
  • N Iwai, H Nakamura, M Miyazu, K Kasai, Y Watanabe, Y Taneda, T Ozaki, S Matsui, T Maki, N Tauchi. [Laboratory and clinical evaluations of flomoxef sodium in neonates]. The Japanese journal of antibiotics. 1991 Nov; 44(11):1265-85. doi: NULL. [PMID: 1784077]
  • K Okura, M Yamakawa, S Kuroki, T Haruta, Y Kobayashi. [Clinical evaluation of flomoxef in neonatal infections]. The Japanese journal of antibiotics. 1991 Nov; 44(11):1286-93. doi: NULL. [PMID: 1784078]
  • K Tomimasu, Y Tsuji, M Fukuda, M Sakai, S Nakashita, T Uchida, G Mori, H Miyazoe, K Motoyama. [Pharmacokinetic and clinical studies on flomoxef in mature and premature infant]. The Japanese journal of antibiotics. 1991 Nov; 44(11):1294-302. doi: NULL. [PMID: 1784079]
  • H Akita, Y Sato, S Iwata, K Sunakawa, T Yokota. [Pharmacokinetic and clinical studies on flomoxef in neonates and premature infants]. The Japanese journal of antibiotics. 1991 Nov; 44(11):1240-9. doi: NULL. [PMID: 1784074]
  • S Azagami, E Isohata, S Takeda, Y Kin, T Oikawa, M Osano, H Shiro. [Pharmacokinetics and clinical efficacy of flomoxef in neonates]. The Japanese journal of antibiotics. 1991 Nov; 44(11):1228-39. doi: NULL. [PMID: 1784073]
  • H Sato, A Narita, K Matsumoto, S Nakazawa, H Suzuki, Y Nakanishi, K Nagao, S Nakazawa, K Niinou. [Studies of flomoxef in neonates]. The Japanese journal of antibiotics. 1991 Nov; 44(11):1250-8. doi: NULL. [PMID: 1784075]
  • K Kimura, T Miyano, H Shimomura. [Pharmacokinetic studies of flomoxef in the neonatal field]. The Japanese journal of antibiotics. 1991 Nov; 44(11):1303-6. doi: NULL. [PMID: 1784080]
  • K Fujita, K Murono, M Saijyo, F Kakuya, H Yoshioka, S Maruyama, H Sakata, A Hiramoto, F Inyaku. [Flomoxef in neonates and young infants; clinical efficacy, pharmacokinetic evaluation and effect on the intestinal bacterial flora]. The Japanese journal of antibiotics. 1991 Nov; 44(11):1216-27. doi: NULL. [PMID: 1784072]
  • T Yamamoto, J Yasuda, H Okada, K Iwasaku. [Pharmacokinetic and clinical studies on flomoxef in the perinatal period in obstetrics and gynecology]. The Japanese journal of antibiotics. 1991 Jun; 44(6):689-96. doi: NULL. [PMID: 1890730]
  • K Ito, H Mikamo, T Tamaya, Y Yamada, M Hayasaki. [Pharmacokinetic and clinical studies on flomoxef in perinatal period]. The Japanese journal of antibiotics. 1991 Jun; 44(6):683-8. doi: NULL. [PMID: 1890729]
  • N Cho, K Fukunaga, K Kunii, I Kobayashi. [Studies on flomoxef in the perinatal period]. The Japanese journal of antibiotics. 1991 Jun; 44(6):674-82. doi: NULL. [PMID: 1890728]
  • S Matsuda, H Hirayama, K Oh. [Pharmacokinetic and clinical studies of flomoxef in perinatal period]. The Japanese journal of antibiotics. 1991 Jun; 44(6):669-73. doi: NULL. [PMID: 1890727]
  • S Makinoda, H Tsuruta, M Iwaki, H Negishi, K Hanatani, T Tanaka, S Fujimoto. [Placental transfer and pharmacokinetic parameters of flomoxef during the perinatal period]. The Japanese journal of antibiotics. 1991 Jun; 44(6):652-8. doi: NULL. [PMID: 1890724]
  • K Tamate, K Sengoku, M Ishikawa, T Shimizu, H Haga, T Hasegawa, H Takada, K Mure, M Kawamura, Y Torii. [Study on flomoxef in the perinatal period]. The Japanese journal of antibiotics. 1991 Jun; 44(6):643-51. doi: NULL. [PMID: 1890723]
  • Y Inamoto, J Goto, K Sakane, T Kamimura, T Takaya. Studies on beta-lactam antibiotics. XIX. Structure-activity relationships of cephalosporins having a thiadiazolylthiomethyl group at the C-3 side chain. The Journal of antibiotics. 1991 May; 44(5):507-16. doi: 10.7164/antibiotics.44.507. [PMID: 2061194]
  • M Ito, T Ishigami. The meaning of the development of flomoxef and clinical experience in Japan. Infection. 1991; 19 Suppl 5(?):S253-7. doi: 10.1007/bf01645536. [PMID: 1783441]
  • K Andrassy, J Koderisch, K Gorges, H Sonntag, K Hirauchi. Pharmacokinetics and hemostasis following administration of a new, injectable oxacephem (6315-S, flomoxef) in volunteers and in patients with renal insufficiency. Infection. 1991; 19 Suppl 5(?):S296-302. doi: 10.1007/bf01645542. [PMID: 1783446]
  • M Imaizumi, H Watanabe, T Ojika, K Fujita, M Sakakibara, D Kondo, M Nishimura, T Abe. [A clinical study on pulmonary tissue uptake of flomoxef]. The Japanese journal of antibiotics. 1991 Jan; 44(1):22-34. doi: NULL. [PMID: 2041145]
  • H Saito, T Kimura, T Takeda, S Kishimoto, T Oguma, K Shimamura. Pharmacokinetics of flomoxef in mucosal tissue of the middle ear and mastoid following intravenous administration in humans. Chemotherapy. 1990; 36(3):193-9. doi: 10.1159/000238766. [PMID: 2338030]
  • K Uchida, T Matsubara, K Hirauchi. Studies on oxacephem antibiotics: comparison of the effects of 1-oxa and 1-thia cephalosporins on blood coagulation activities and vitamin K metabolism in rats. Japanese journal of pharmacology. 1989 Jul; 50(3):283-8. doi: 10.1254/jjp.50.283. [PMID: 2761130]
  • M Ooishi, F Sakaue, A Oomomo, H Tazawa. [Microbiological and pharmacokinetic studies on flomoxef in ophthalmologic field]. The Japanese journal of antibiotics. 1989 May; 42(5):1194-8. doi: NULL. [PMID: 2746859]
  • S Ida, K Nishioka, T Takishima. [Clinical trials of flomoxef in patients with chronic respiratory tract infections]. The Japanese journal of antibiotics. 1988 May; 41(5):571-6. doi: NULL. [PMID: 3063850]
  • T Obata, K Koishi, J Sasaki, M Eguchi, Y Yamamoto. [Studies on antimicrobial concentrations of flomoxef in serum, pelvic dead space exudate, and pelvic organs/tissues]. The Japanese journal of antibiotics. 1987 Oct; 40(10):1820-9. doi: NULL. [PMID: 3444023]
  • T Yokoyama, T Kodama, Y Takesue, M Fujimoto, E Hiyama, T Ichikawa. [Studies on antibacterial activity of flomoxef and its distribution to serum and intraperitoneal exudate in surgery]. The Japanese journal of antibiotics. 1987 Oct; 40(10):1809-19. doi: NULL. [PMID: 3444022]
  • H Sato, A Narita, S Nakazawa, H Suzuki, K Mastumoto, Y Nakanishi, S Nakazawa, K Niino, Y Nakada. [The study of flomoxef in the pediatric field]. The Japanese journal of antibiotics. 1987 Aug; 40(8):1349-63. doi: . [PMID: 3430712]
  • T Motohiro, K Oda, M Aramaki, A Kawakami, K Tanaka, T Koga, Y Shimada, S Tomita, Y Sakata, T Fujimoto. [Pharmacokinetics and clinical studies of flomoxef in the pediatric field]. The Japanese journal of antibiotics. 1987 Aug; 40(8):1515-34. doi: NULL. [PMID: 3430727]
  • T Okada, S Furukawa. [Clinical evaluation of flomoxef in pediatrics and a study on the penetration into cerebrospinal fluid]. The Japanese journal of antibiotics. 1987 Aug; 40(8):1477-85. doi: NULL. [PMID: 3430723]
  • K Kuno, Y Nakao, F Hayakawa, K Miura, Y Miyajima, H Ishikawa, H Kimura. [Bacteriological and clinical studies of flomoxef in the field of pediatrics]. The Japanese journal of antibiotics. 1987 Aug; 40(8):1393-406. doi: NULL. [PMID: 3430715]
  • H Meguro, O Arimasu, K Sugamata, H Shiraishi, M Kobayashi, R Fujii, J Mashiko, Y Nagao, Y Okamoto. [Clinical evaluation of flomoxef in children]. The Japanese journal of antibiotics. 1987 Aug; 40(8):1337-48. doi: NULL. [PMID: 3430711]
  • T Hosoda, T Ichioka, M Miyao. [Pharmacokinetic and clinical experience with flomoxef in bacterial infection in children]. The Japanese journal of antibiotics. 1987 Aug; 40(8):1462-8. doi: NULL. [PMID: 3430721]
  • H Higashino, T Kobayashi, K Shuto, T Matsui, M Hasui, S Nogi, Y Adachi, Y Kobayashi, A Araki, N Sonoda. [Clinical and pharmacokinetics evaluation of flomoxef in pediatrics]. The Japanese journal of antibiotics. 1987 Aug; 40(8):1439-46. doi: NULL. [PMID: 3430719]
  • T Morimoto, K Kida, H Matsuda, M Murase. [Clinical studies of flomoxef in the pediatric field]. The Japanese journal of antibiotics. 1987 Aug; 40(8):1486-95. doi: NULL. [PMID: 3430724]
  • T Nishimura, K Tabuki, S Aoki, M Takagi. [Laboratory and clinical studies of flomoxef in the pediatric field]. The Japanese journal of antibiotics. 1987 Aug; 40(8):1426-38. doi: NULL. [PMID: 3430718]
  • N Iwai, M Miyazu, H Nakamura, M Katayama, K Kasai, Y Taneda. [Pharmacokinetical, bacteriological and clinical studies of flomoxef in the pediatric field]. The Japanese journal of antibiotics. 1987 Aug; 40(8):1377-91. doi: NULL. [PMID: 3430714]