Pentoxyresorufin (BioDeep_00000792912)
代谢物信息卡片
Resorufin pentyl ether
化学式: C17H17NO3 (283.1208372)
中文名称: 7-(戊氧基)-3H-吩噁嗪-3-酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCOC1=CC2=C(C=C1)N=C3C=CC(=O)C=C3O2
InChI: InChI=1S/C17H17NO3/c1-2-3-4-9-20-13-6-8-15-17(11-13)21-16-10-12(19)5-7-14(16)18-15/h5-8,10-11H,2-4,9H2,1H3
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Daniel V Iwamoto, Chad M Kurylo, Kelly M Schorling, Wade H Powell. Induction of cytochrome P450 family 1 mRNAs and activities in a cell line from the frog Xenopus laevis.
Aquatic toxicology (Amsterdam, Netherlands).
2012 Jun; 114-115(?):165-72. doi:
10.1016/j.aquatox.2012.02.028. [PMID: 22446828] - Christiaan J Malherbe, Dalene De Beer, Elizabeth Joubert. Development of on-line high performance liquid chromatography (HPLC)-biochemical detection methods as tools in the identification of bioactives.
International journal of molecular sciences.
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10.3390/ijms13033101. [PMID: 22489144] - Hiroshi Yamazaki, Kana Horiuchi, Ryohji Takano, Taku Nagano, Makiko Shimizu, Masato Kitajima, Norie Murayama, Fumiaki Shono. Human blood concentrations of cotinine, a biomonitoring marker for tobacco smoke, extrapolated from nicotine metabolism in rats and humans and physiologically based pharmacokinetic modeling.
International journal of environmental research and public health.
2010 09; 7(9):3406-21. doi:
10.3390/ijerph7093406. [PMID: 20948932] - Lisa B Helgason, Augustine Arukwe, Geir W Gabrielsen, Mikael Harju, Marit N Hegseth, Eldbjørg S Heimstad, Even H Jørgensen, Anne S Mortensen, Johannes Wolkers. Biotransformation of PCBs in Arctic seabirds: characterization of phase I and II pathways at transcriptional, translational and activity levels.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2010 Jun; 152(1):34-41. doi:
10.1016/j.cbpc.2010.02.009. [PMID: 20176133] - N Konsue, C Ioannides. Tissue differences in the modulation of rat cytochromes P450 and phase II conjugation systems by dietary doses of phenethyl isothiocyanate.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2008 Dec; 46(12):3677-83. doi:
10.1016/j.fct.2008.09.046. [PMID: 18929617] - Augustine Arukwe, Trond Nordtug, Trond M Kortner, Anne S Mortensen, Odd Gunnar Brakstad. Modulation of steroidogenesis and xenobiotic biotransformation responses in zebrafish (Danio rerio) exposed to water-soluble fraction of crude oil.
Environmental research.
2008 Jul; 107(3):362-70. doi:
10.1016/j.envres.2008.02.009. [PMID: 18396270] - Magnus Lundgren, Per Ola Darnerud, Ylva Molin, Hellmuth Lilienthal, Jonas Blomberg, Nils-Gunnar Ilbäck. Viral infection and PBDE exposure interact on CYP gene expression and enzyme activities in the mouse liver.
Toxicology.
2007 Dec; 242(1-3):100-8. doi:
10.1016/j.tox.2007.09.014. [PMID: 17964055] - Sasan Mosadeghi, Bjarte Furnes, Aline Y O Matsuo, Daniel Schlenk. Expression and characterization of cytochrome P450 2X1 in channel catfish (Ictalurus punctatus).
Biochimica et biophysica acta.
2007 Jul; 1770(7):1045-52. doi:
10.1016/j.bbagen.2007.03.008. [PMID: 17459590] - Eivor Elovaara, Helene Stockmann-Juvala, Jouni Mikkola, Harry V Gelboin. Interactive effects of methyl tertiary-butyl ether (MTBE) and tertiary-amyl methyl ether (TAME), ethanol and some drugs: Triglyceridemia, liver toxicity and induction of CYP (2E1, 2B1) and phase II enzymes in female Wistar rats.
Environmental toxicology and pharmacology.
2007 Jan; 23(1):64-72. doi:
10.1016/j.etap.2006.07.003. [PMID: 21783738] - Wei-Hung Chan, Wei-Zen Sun, Tzuu-Huei Ueng. Induction of rat hepatic cytochrome P-450 by ketamine and its toxicological implications.
Journal of toxicology and environmental health. Part A.
2005 Sep; 68(17-18):1581-97. doi:
10.1080/15287390590967522. [PMID: 16076768] - Marcella Martignoni, Ruben de Kanter, Anna Moscone, Pietro Grossi, Mario Monshouwer. Lack of strain-related differences in drug metabolism and efflux transporter characteristics between CD-1 and athymic nude mice.
Cancer chemotherapy and pharmacology.
2005 Feb; 55(2):129-35. doi:
10.1007/s00280-004-0898-7. [PMID: 15592720] - Victoria Yoxall, Meera Umachandran, Judith Wilson, Peter Kentish, Costas Ioannides. Black tea intake modulates the excretion of urinary mutagens in rats exposed to 6-aminochrysene: induction of cytochromes P450 by 6-aminochrysene in the rat.
Mutagenesis.
2005 Jan; 20(1):23-8. doi:
10.1093/mutage/gei002. [PMID: 15598702] - Susana Yenes, Jan N M Commandeur, Nico P E Vermeulen, Angel Messeguer. In vitro biotransformation of 3,4-dihydro-6-hydroxy-2,2-dimethyl-7-methoxy-1(2H)-benzopyran (CR-6), a potent lipid peroxidation inhibitor and nitric oxide scavenger, in rat liver microsomes.
Chemical research in toxicology.
2004 Jul; 17(7):904-13. doi:
10.1021/tx030036f. [PMID: 15257615] - Z Veres, T Szakács, L Vereczkey. Effect of alpha-methyldopa on pentoxyresorufin O-dealkylation in liver microsomes from rats treated with phenobarbital.
Archives of biochemistry and biophysics.
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Artificial organs.
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10.1046/j.1525-1594.1998.06088.x. [PMID: 9790080] - W Klinger, H Oelschläger, E Karge, D Rothley. Interaction of chlormezanone with rat liver microsomes and its degradation.
European journal of drug metabolism and pharmacokinetics.
1997 Apr; 22(2):165-71. doi:
10.1007/bf03189801. [PMID: 9248786] - L D Lehman-McKeeman, D R Johnson, D Caudill. Induction and inhibition of mouse cytochrome P-450 2B enzymes by musk xylene.
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10.1006/taap.1996.7927. [PMID: 9007046] - R W Nims, R M McClain, P S Manchand, P S Belica, P E Thomas, D W Mellini, W E Utermahlen, R A Lubet. Comparative pharmacodynamics of hepatic cytochrome P450 2B induction by 5,5-diphenyl- and 5,5-diethyl-substituted barbiturates and hydantoins in the male F344/NCr rat.
The Journal of pharmacology and experimental therapeutics.
1994 Jul; 270(1):348-55. doi:
. [PMID: 8035330] - P V Nerurkar, S S Park, P E Thomas, R W Nims, R A Lubet. Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse.
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