2,2-Azobis(2-methylpropionamidine) dihydrochloride (BioDeep_00000792870)
代谢物信息卡片
2,2-Azobis(2-methylpropionamidine) dihydrochloride
化学式: C8H20Cl2N6 (270.112642)
中文名称: 2,2-偶氮二(2-甲基丙基咪)二盐酸盐
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(C(=N)N)N=NC(C)(C)C(=N)N.Cl.Cl
InChI: 2*1H
描述信息
D009676 - Noxae > D009153 - Mutagens
D009676 - Noxae > D016877 - Oxidants
同义名列表
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yuan Zheng, Xueyang Ren, Xiaodan Qi, Ruolan Song, Chongjun Zhao, Jiamu Ma, Xianxian Li, Qingyue Deng, Yingyu He, Lingmei Kong, Liyan Qian, Feng Zhang, Mingxia Li, Mengyu Sun, Wei Liu, Haibin Liu, Gaimei She. Bao Yuan decoction alleviates fatigue by restraining inflammation and oxidative stress via the AMPK/CRY2/PER1 signaling pathway.
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Environmental toxicology and pharmacology.
2024 Mar; 106(?):104388. doi:
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BMC complementary medicine and therapies.
2024 Feb; 24(1):75. doi:
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International journal of pharmaceutics.
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Biomolecules.
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Nitric oxide : biology and chemistry.
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Free radical biology & medicine.
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Toxicology mechanisms and methods.
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Journal of controlled release : official journal of the Controlled Release Society.
2014 May; 182(?):67-72. doi:
10.1016/j.jconrel.2014.03.015. [PMID: 24637467] - Elisabete Maciel, Bruno M Neves, Deolinda Santinha, Ana Reis, Pedro Domingues, M Teresa Cruz, Andrew R Pitt, Corinne M Spickett, M Rosário M Domingues. Detection of phosphatidylserine with a modified polar head group in human keratinocytes exposed to the radical generator AAPH.
Archives of biochemistry and biophysics.
2014 Apr; 548(?):38-45. doi:
10.1016/j.abb.2014.02.002. [PMID: 24560783] - Ilaria Peluso, Luca Romanelli, Silvana Spagnuolo, Husseen Manafikhi, Maura Palmery. Serum depletion, multidrug resistance and fluorescent probes: methodological implications in free radicals evaluation.
Journal of immunological methods.
2014 Mar; 405(?):178-80. doi:
10.1016/j.jim.2013.12.009. [PMID: 24389320] - Eun-A Kim, Seung-Hong Lee, Chang-ik Ko, Seon-Heui Cha, Min-Cheol Kang, Sung-Myung Kang, Seok-Chun Ko, Won-Woo Lee, Ju-Young Ko, Ji-Hyeok Lee, Nalae Kang, Jae-Young Oh, Ginnae Ahn, Young Heun Jee, You-Jin Jeon. Protective effect of fucoidan against AAPH-induced oxidative stress in zebrafish model.
Carbohydrate polymers.
2014 Feb; 102(?):185-91. doi:
10.1016/j.carbpol.2013.11.022. [PMID: 24507271] - Jingfei Zhang, Xiang Hou, Hussain Ahmad, Hao Zhang, Lili Zhang, Tian Wang. Assessment of free radicals scavenging activity of seven natural pigments and protective effects in AAPH-challenged chicken erythrocytes.
Food chemistry.
2014 Feb; 145(?):57-65. doi:
10.1016/j.foodchem.2013.08.025. [PMID: 24128449] - E O Omarova, Y N Antonenko. Inhibition of oxidative hemolysis in erythrocytes by mitochondria-targeted antioxidants of SkQ series.
Biochemistry. Biokhimiia.
2014 Feb; 79(2):139-45. doi:
10.1134/s0006297914020072. [PMID: 24794729] - N P Damascena, M T S Souza, A F Almeida, R S Cunha, N P Damascena, R L Curvello, A C B Lima, E C V Almeida, C C S Santos, A S Dias, M S Paixão, L M A Souza, L J Quintans Júnior, C S Estevam, B S Araujo. Antioxidant and orofacial anti-nociceptive activities of the stem bark aqueous extract of Anadenanthera colubrina (Velloso) Brenan (Fabaceae).
Natural product research.
2014; 28(10):753-6. doi:
10.1080/14786419.2013.877902. [PMID: 24438027] - Xiang Hou, Jingfei Zhang, Hussain Ahmad, Hao Zhang, Ziwei Xu, Tian Wang. Evaluation of antioxidant activities of ampelopsin and its protective effect in lipopolysaccharide-induced oxidative stress piglets.
PloS one.
2014; 9(9):e108314. doi:
10.1371/journal.pone.0108314. [PMID: 25268121] - Min-Cheol Kang, Seo Young Kim, Yoon Taek Kim, Eun-A Kim, Seung-Hong Lee, Seok-Chun Ko, W A J P Wijesinghe, Kalpa W Samarakoon, Young-Sun Kim, Jin Hun Cho, Hyeang-Su Jang, You-Jin Jeon. In vitro and in vivo antioxidant activities of polysaccharide purified from aloe vera (Aloe barbadensis) gel.
Carbohydrate polymers.
2014 Jan; 99(?):365-71. doi:
10.1016/j.carbpol.2013.07.091. [PMID: 24274519] - Ju-Young Ko, Eun-A Kim, Ji-Hyeok Lee, Min-Cheol Kang, Jung-Suck Lee, Jin-Soo Kim, Won-Kyo Jung, You-Jin Jeon. Protective effect of aquacultured flounder fish-derived peptide against oxidative stress in zebrafish.
Fish & shellfish immunology.
2014 Jan; 36(1):320-3. doi:
10.1016/j.fsi.2013.11.018. [PMID: 24333583] - K Vanaja, M A Wahl, L Bukarica, H Heinle. Liposomes as carriers of the lipid soluble antioxidant resveratrol: evaluation of amelioration of oxidative stress by additional antioxidant vitamin.
Life sciences.
2013 Dec; 93(24):917-23. doi:
10.1016/j.lfs.2013.10.019. [PMID: 24177602] - J Courraud, C Charnay, J P Cristol, J Berger, S Avallone. In vitro lipid peroxidation of intestinal bile salt-based nanoemulsions: potential role of antioxidants.
Free radical research.
2013 Dec; 47(12):1076-87. doi:
10.3109/10715762.2013.853877. [PMID: 24128050] - Yonathan Asikin, Makoto Takahashi, Takashi Mishima, Masami Mizu, Kensaku Takara, Koji Wada. Antioxidant activity of sugarcane molasses against 2,2'-azobis(2-amidinopropane) dihydrochloride-induced peroxyl radicals.
Food chemistry.
2013 Nov; 141(1):466-72. doi:
10.1016/j.foodchem.2013.03.045. [PMID: 23768381] - K S Fernandes, A H M Silva, S A Mendanha, K R Rezende, A Alonso. Antioxidant effect of 4-nerolidylcatechol and α-tocopherol in erythrocyte ghost membranes and phospholipid bilayers.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
2013 Sep; 46(9):780-8. doi:
10.1590/1414-431x20132940. [PMID: 24068194] - Min-Cheol Kang, Seon Heui Cha, W A J P Wijesinghe, Sung-Myung Kang, Seung-Hong Lee, Eun-A Kim, Choon Bok Song, You-Jin Jeon. Protective effect of marine algae phlorotannins against AAPH-induced oxidative stress in zebrafish embryo.
Food chemistry.
2013 Jun; 138(2-3):950-5. doi:
10.1016/j.foodchem.2012.11.005. [PMID: 23411200] - Ilaria Peluso, Gaspare Adorno, Anna Raguzzini, Lourdes Urban, Andrea Ghiselli, Mauro Serafini. A new flow cytometry method to measure oxidative status: the Peroxidation of Leukocytes Index Ratio (PLIR).
Journal of immunological methods.
2013 Apr; 390(1-2):113-20. doi:
10.1016/j.jim.2013.02.005. [PMID: 23454245] - Fan Li, Jian-Hong Wu, Qing-Hua Wang, Yuan-Lan Shu, Chun-Wai Wan, Chi-On Chan, Daniel Kam-Wah Mok, Shun-Wan Chan. Gui-ling-gao, a traditional Chinese functional food, prevents oxidative stress-induced apoptosis in H9c2 cardiomyocytes.
Food & function.
2013 Apr; 4(5):745-53. doi:
10.1039/c3fo30182f. [PMID: 23467630] - Rangaswamy Lakshminarayana, Gorusupudi Aruna, Upparahalli V Sathisha, Shylaja M Dharmesh, Vallikannan Baskaran. Structural elucidation of possible lutein oxidation products mediated through peroxyl radical inducer 2,2'-Azobis (2-methylpropionamidine) dihydrochloride: antioxidant and cytotoxic influence of oxidized lutein in HeLa cells.
Chemico-biological interactions.
2013 Apr; 203(2):448-55. doi:
10.1016/j.cbi.2013.03.006. [PMID: 23518229] - Shawn N Watson, Natasha Wright, Petra M Hermann, Willem C Wildering. Phospholipase A₂: the key to reversing long-term memory impairment in a gastropod model of aging.
Neurobiology of aging.
2013 Feb; 34(2):610-20. doi:
10.1016/j.neurobiolaging.2012.02.028. [PMID: 22459601] - Jia-Yu Wang, Jeremy Marks, Ka Yee C Lee. Nature of interactions between PEO-PPO-PEO triblock copolymers and lipid membranes: (I) effect of polymer hydrophobicity on its ability to protect liposomes from peroxidation.
Biomacromolecules.
2012 Sep; 13(9):2616-23. doi:
10.1021/bm300847x. [PMID: 22808900] - Yusei Kashima, Mitsuo Miyazawa. Synthesis and biological evaluation of bergenin analogues as mushroom tyrosinase inhibitors.
Archives of pharmacal research.
2012 Sep; 35(9):1533-41. doi:
10.1007/s12272-012-0903-3. [PMID: 23054709] - Peter A C McPherson, Amanda Bole, Kenneth A Cruz, Ian S Young, Jane McEneny. A curvilinear approach to the kinetic analysis of linoleate peroxidation in aqueous liposomes by 2,2'azobis(2-amidoinopropane) dihydrochloride.
Chemistry and physics of lipids.
2012 Sep; 165(6):682-8. doi:
10.1016/j.chemphyslip.2012.07.004. [PMID: 22841574] - Sara Elsøe, Josefin Ahnström, Christina Christoffersen, Andrew N Hoofnagle, Peter Plomgaard, Jay W Heinecke, Christoph J Binder, Harry Björkbacka, Björn Dahlbäck, Lars B Nielsen. Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL.
Atherosclerosis.
2012 Mar; 221(1):91-7. doi:
10.1016/j.atherosclerosis.2011.11.031. [PMID: 22204862] - Joseph A Laszlo, Kervin O Evans, David L Compton, Michael Appell. Dihydrolipoyl dioleoylglycerol antioxidant capacity in phospholipid vesicles.
Chemistry and physics of lipids.
2012 Feb; 165(2):160-8. doi:
10.1016/j.chemphyslip.2011.12.003. [PMID: 22197684] - Anat Elmann, Alona Telerman, Sharon Mordechay, Hilla Erlank, Rivka Ofir. Antioxidant and astroprotective effects of a Pulicaria incisa infusion.
Oxidative medicine and cellular longevity.
2012; 2012(?):157598. doi:
10.1155/2012/157598. [PMID: 23320126] - Laura Zambonin, Cristiana Caliceti, Francesco Vieceli Dalla Sega, Diana Fiorentini, Silvana Hrelia, Laura Landi, Cecilia Prata. Dietary phenolic acids act as effective antioxidants in membrane models and in cultured cells, exhibiting proapoptotic effects in leukaemia cells.
Oxidative medicine and cellular longevity.
2012; 2012(?):839298. doi:
10.1155/2012/839298. [PMID: 22792417] - Shawn N Watson, Mark A Nelson, Willem C Wildering. Redox agents modulate neuronal activity and reproduce physiological aspects of neuronal aging.
Neurobiology of aging.
2012 Jan; 33(1):149-61. doi:
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Bioorganic & medicinal chemistry letters.
2012 Jan; 22(1):634-7. doi:
10.1016/j.bmcl.2011.10.063. [PMID: 22113113] - Monika A Olszewska. In vitro antioxidant activity and total phenolic content of the inflorescences, leaves and fruits of Sorbus torminalis (L.) Crantz.
Acta poloniae pharmaceutica.
2011 Nov; 68(6):945-53. doi:
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Acta poloniae pharmaceutica.
2011 Nov; 68(6):937-44. doi:
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Journal of ethnopharmacology.
2011 Sep; 137(1):669-80. doi:
10.1016/j.jep.2011.06.017. [PMID: 21718778] - Haobin Zhang, Tianfeng Chen, Jie Jiang, Yum-Shing Wong, Fang Yang, Wenjie Zheng. Selenium-containing allophycocyanin purified from selenium-enriched Spirulina platensis attenuates AAPH-induced oxidative stress in human erythrocytes through inhibition of ROS generation.
Journal of agricultural and food chemistry.
2011 Aug; 59(16):8683-90. doi:
10.1021/jf2019769. [PMID: 21761878] - Rômulo Pillon Barcelos, Rafael de Lima Portella, Edovando José Flores da Rosa, Alexandra de Souza Fonseca, Leandro Bresolin, Vanessa Carratu, Félix Alexandre Antunes Soares, Nilda Vargas Barbosa. Thiosemicarbazone derivate protects from AAPH and Cu2+ -induced LDL oxidation.
Life sciences.
2011 Jul; 89(1-2):20-8. doi:
10.1016/j.lfs.2011.04.026. [PMID: 21620869] - Jean-François Lesgards, Cyrielle Gauthier, Juan Iovanna, Nicolas Vidal, Alain Dolla, Pierre Stocker. Effect of reactive oxygen and carbonyl species on crucial cellular antioxidant enzymes.
Chemico-biological interactions.
2011 Mar; 190(1):28-34. doi:
10.1016/j.cbi.2010.12.028. [PMID: 21216240] - Junhwan Kim, Paul E Minkler, Robert G Salomon, Vernon E Anderson, Charles L Hoppel. Cardiolipin: characterization of distinct oxidized molecular species.
Journal of lipid research.
2011 Jan; 52(1):125-35. doi:
10.1194/jlr.m010520. [PMID: 20858593] - Monika A Olszewska, Sławomira Nowak, Piotr Michel, Piotr Banaszczak, Agnieszka Kicel. Assessment of the content of phenolics and antioxidant action of inflorescences and leaves of selected species from the genus Sorbus sensu stricto.
Molecules (Basel, Switzerland).
2010 Dec; 15(12):8769-83. doi:
10.3390/molecules15128769. [PMID: 21127463] - Dharmendra Kumar Maurya, Thomas Paul Asir Devasagayam. Antioxidant and prooxidant nature of hydroxycinnamic acid derivatives ferulic and caffeic acids.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2010 Dec; 48(12):3369-73. doi:
10.1016/j.fct.2010.09.006. [PMID: 20837085] - Antony F McDonagh. The biliverdin-bilirubin antioxidant cycle of cellular protection: Missing a wheel?.
Free radical biology & medicine.
2010 Sep; 49(5):814-20. doi:
10.1016/j.freeradbiomed.2010.06.001. [PMID: 20547221]