Diflucortolone (BioDeep_00000790749)
代谢物信息卡片
化学式: C22H28F2O4 (394.1955552)
中文名称: 双氟可龙
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1C(=O)CO)C)O)F)C)F
InChI: InChI=1S/C22H28F2O4/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-21(15,3)22(14,24)18(28)9-20(13,2)19(11)17(27)10-25/h4-5,7,11,13-14,16,18-19,25,28H,6,8-10H2,1-3H3/t11-,13+,14+,16+,18+,19-,20+,21+,22+/m1/s1
描述信息
D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07X - Corticosteroids, other combinations > D07XC - Corticosteroids, potent, other combinations
D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AC - Corticosteroids, potent (group iii)
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
D000893 - Anti-Inflammatory Agents
同义名列表
1 个代谢物同义名
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:135624
- KEGGdrug: D03812
- PubChem: 11954369
- DrugBank: DB09095
- ChEMBL: CHEMBL509924
- MeSH: Diflucortolone
- CAS: 2607-06-9
分类词条
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Fatma S Abdel-Salam, Azza A Mahmoud, Hussein O Ammar, Seham A Elkheshen. Nanostructured lipid carriers as semisolid topical delivery formulations for diflucortolone valerate.
Journal of liposome research.
2017 Mar; 27(1):41-55. doi:
10.3109/08982104.2016.1149866. [PMID: 26956098] - Hye Rang On, Sang Eun Lee, You Chan Kim, Soo-Chan Kim. Isolated benign primary cutaneous plasmacytosis in a child.
Pediatric dermatology.
2014 Nov; 31(6):e120-1. doi:
10.1111/pde.12449. [PMID: 25424220] - Taku Fujimura, Ryuhei Okuyama, Eisaku Ogawa, Setsuya Aiba. Papuloerythroderma associated with monoclonal gammopathy of undetermined significance.
The Journal of dermatology.
2009 Apr; 36(4):228-31. doi:
10.1111/j.1346-8138.2009.00628.x. [PMID: 19348662] - Ayla Güven, Ozlem Gülümser, Tolga Ozgen. Cushing's syndrome and adrenocortical insufficiency caused by topical steroids: misuse or abuse?.
Journal of pediatric endocrinology & metabolism : JPEM.
2007 Nov; 20(11):1173-82. doi:
10.1515/jpem.2007.20.11.1173. [PMID: 18183788] - Taku Fujimura, Ryuhei Okuyama, Satoshi Nakagawa, Tadashi Terui, Setsuya Aiba. Generalized mucinosis in a patient with erythroderma.
Dermatology (Basel, Switzerland).
2006; 212(4):366-9. doi:
10.1159/000092288. [PMID: 16707887] - H Saeki, S Muneta, T Kobayashi, Y Hirota. [Septicemia due to methicillin-resistant Staphylococcus aureus from chronic prurigo in an elderly woman].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics.
1997 Aug; 34(8):672-7. doi:
10.3143/geriatrics.34.672. [PMID: 9396325] - U Täuber, C Weiss, H Matthes. Does salicylic acid increase the percutaneous absorption of diflucortolone-21-valerate?.
Skin pharmacology : the official journal of the Skin Pharmacology Society.
1993; 6(4):276-81. doi:
10.1159/000211150. [PMID: 8198813] - M Kimura, Y Tarumoto, S Nakane, S Otomo. Comparative toxicity study of hydrocortisone 17-butyrate 21-propionate (HBP) ointment and other topical corticosteroids in rats.
Drugs under experimental and clinical research.
1986; 12(8):643-52. doi:
. [PMID: 3757761] - P Aertgeerts, M Albring, F Klaschka, T Nasemann, R Patzelt-Wenczler, K Rauhut, B Weigl. [Comparative testing of Kamillosan cream and steroidal (0.25\% hydrocortisone, 0.75\% fluocortin butyl ester) and non-steroidal (5\% bufexamac) dermatologic agents in maintenance therapy of eczematous diseases].
Zeitschrift fur Hautkrankheiten.
1985 Feb; 60(3):270-7. doi:
". [PMID: 3158124] - C Queille, R Pommarede, J H Saurat. Efficacy versus systemic effects of six topical steroids in the treatment of atopic dermatitis of childhood.
Pediatric dermatology.
1984 Jan; 1(3):246-53. doi:
10.1111/j.1525-1470.1984.tb01124.x. [PMID: 6494068] - V W Mützel. [Pharmacokinetics and biotransformation of diflucortolone valerate in man (author's transl)].
Arzneimittel-Forschung.
1976; 26(7b):1487-92. doi:
NULL. [PMID: 1036944]