Valganciclovir Hydrochloride (BioDeep_00000790637)
代谢物信息卡片
化学式: C14H23ClN6O5 (390.1418378)
中文名称: 缬更昔洛韦盐酸盐
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)C(C(=O)OCC(CO)OCN1C=NC2=C1N=C(NC2=O)N)N.Cl
InChI: /m0./s1
描述信息
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
C471 - Enzyme Inhibitor > C29575 - DNA Polymerase Inhibitor
C254 - Anti-Infective Agent > C281 - Antiviral Agent
Valganciclovir hydrochloride is an orally active antiviral agent. Valganciclovir hydrochloride can inhibit the growth of adenoviruses and have a protective effect on immunosuppressed hamsters. Valganciclovir hydrochloride can be used for the research of Cytomegalovirus[1][2][3].
同义名列表
数据库引用编号
6 个数据库交叉引用编号
- KEGGdrug: D03256
- PubChem: 135413534
- ChEMBL: CHEMBL1200454
- MeSH: Valganciclovir
- CAS: 175865-59-5
- medchemexpress: HY-A0032A
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- G Clement Dobbins, David W Kimberlin, Shannon A Ross. Cytomegalovirus variation among newborns treated with valganciclovir.
Antiviral research.
2022 07; 203(?):105326. doi:
10.1016/j.antiviral.2022.105326
. [PMID: 35504491] - Diana D Wong, Wendy J van Zuylen, Talia Novos, Sophie Stocker, Stephanie E Reuter, Jane Au, Charles S P Foster, Richard O Day, Andrea R Horvath, Zoltan Endre, William D Rawlinson. Detection of Ganciclovir-Resistant Cytomegalovirus in a Prospective Cohort of Kidney Transplant Recipients Receiving Subtherapeutic Valganciclovir Prophylaxis.
Microbiology spectrum.
2022 06; 10(3):e0268421. doi:
10.1128/spectrum.02684-21
. [PMID: 35658598] - Pablo Rojo, Cinta Moraleda, Alfredo Tagarro, Sara Domínguez-Rodríguez, Lola Madrid Castillo, Luis Manuel Prieto Tato, Aranzazu Sancho López, Lilit Manukyan, Olivier Marcy, Valeriane Leroy, Alessandra Nardone, David Burger, Quique Bassat, Matthew Bates, Raoul Moh, Pui-Ying Iroh Tam, Tisungane Mvalo, Justina Magallhaes, W Chris Buck, Jahit Sacarlal, Victor Musiime, Chishala Chabala, Hilda Angela Mujuru. Empirical treatment against cytomegalovirus and tuberculosis in HIV-infected infants with severe pneumonia: study protocol for a multicenter, open-label randomized controlled clinical trial.
Trials.
2022 Jun; 23(1):531. doi:
10.1186/s13063-022-06203-1
. [PMID: 35761406] - Rachel Hellemans, Daniel Abramowicz. Cytomegalovirus after kidney transplantation in 2020: moving towards personalized prevention.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2022 04; 37(5):810-816. doi:
10.1093/ndt/gfaa249
. [PMID: 33280028] - Sandeep Brar, Reyoot Berry, Amit D Raval, Yuexin Tang, Flavio Vincenti, Nikolaos Skartsis. Outcomes among CMV-mismatched and highly sensitized kidney transplants recipients who develop neutropenia.
Clinical transplantation.
2022 04; 36(4):e14583. doi:
10.1111/ctr.14583
. [PMID: 34984735] - Margaret R Jorgenson, Hanna Kleiboeker, Neetika Garg, Sandesh Parajuli, Didier A Mandelbrot, Jon S Odorico, Christopher M Saddler, Jeannina A Smith. Letermovir conversion after valganciclovir treatment in cytomegalovirus high-risk abdominal solid organ transplant recipients may promote development of cytomegalovirus-specific cell mediated immunity.
Transplant infectious disease : an official journal of the Transplantation Society.
2022 Feb; 24(1):e13766. doi:
10.1111/tid.13766
. [PMID: 34799964] - Narisa Ruenroengbun, Tunlanut Sapankaew, Kamolpat Chaiyakittisopon, Pakpoom Phoompoung, Thundon Ngamprasertchai. Efficacy and Safety of Antiviral Agents in Preventing Allograft Rejection Following CMV Prophylaxis in High-Risk Kidney Transplantation: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.
Frontiers in cellular and infection microbiology.
2022; 12(?):865735. doi:
10.3389/fcimb.2022.865735
. [PMID: 35433502] - Yiyun Shi, Alexis Hope Lerner, Ralph Rogers, Kendra Vieira, Basma Merhi, Krista Mecadon, Adena J Osband, George Bayliss, Reginald Gohh, Paul Morrissey, Dimitrios Farmakiotis. Low-Dose Valganciclovir Prophylaxis Is Safe and Cost-Saving in CMV-Seropositive Kidney Transplant Recipients.
Progress in transplantation (Aliso Viejo, Calif.).
2021 12; 31(4):368-376. doi:
10.1177/15269248211046037
. [PMID: 34839729] - Helen Pizzo, Bongha Shin, Jon Garrison, Edmund Huang, Mohammad Malekzadeh, Stanley C Jordan, Dechu Puliyanda, Mieko Toyoda. Development of CMV-specific cytotoxic T cells (CMV-Tc) in pediatric renal transplant recipients with CMV viremia.
Pediatric transplantation.
2021 12; 25(8):e14119. doi:
10.1111/petr.14119
. [PMID: 34390094] - Elena Rho, Bettina Näf, Thomas F Müller, Rudolf P Wüthrich, Thomas Schachter, Seraina von Moos. Use of letermovir-valganciclovir combination as a step-down treatment after foscarnet for ganciclovir-resistant CMV infection in kidney transplant recipients.
Clinical transplantation.
2021 11; 35(11):e14401. doi:
10.1111/ctr.14401
. [PMID: 34181768] - Bénédicte Franck, Julie Autmizguine, Anders Åsberg, Yves Théorêt, Pierre Marquet, Philippe Ovetchkine, Jean-Baptiste Woillard. Thoroughly Validated Bayesian Estimator and Limited Sampling Strategy for Dose Individualization of Ganciclovir and Valganciclovir in Pediatric Transplant Recipients.
Clinical pharmacokinetics.
2021 11; 60(11):1449-1462. doi:
10.1007/s40262-021-01034-w
. [PMID: 34050910] - Alexandra L Bixby, Linda Fitzgerald, Jeong M Park, Daniel Kaul, Sarah Tischer. Comparison of standard versus low-dose valganciclovir regimens for cytomegalovirus prophylaxis in high-risk liver transplant recipients.
Transplant infectious disease : an official journal of the Transplantation Society.
2021 Oct; 23(5):e13713. doi:
10.1111/tid.13713
. [PMID: 34428337] - Amanda Vinson, Alyne Teixeira, Bryce Kiberd, Karthik Tennankore. Predictors and Complications of Post Kidney Transplant Leukopenia.
Progress in transplantation (Aliso Viejo, Calif.).
2021 09; 31(3):249-256. doi:
10.1177/15269248211024614
. [PMID: 34159855] - Margaret R Jorgenson, Cynthia Wong, Jillian L Descourouez, Christopher M Saddler, Jeannina A Smith, Didier A Mandelbrot. Conversion from cytomegalovirus universal prophylaxis with valganciclovir to the preemptive monitoring approach to manage leukopenia after kidney or pancreas transplantation.
Transplant infectious disease : an official journal of the Transplantation Society.
2021 Aug; 23(4):e13617. doi:
10.1111/tid.13617
. [PMID: 33866643] - Bénédicte Franck, Jean-Baptiste Woillard, Yves Théorêt, Henrique Bittencourt, Emile Demers, Annabelle Briand, Pierre Marquet, Anne-Laure Lapeyraque, Philippe Ovetchkine, Julie Autmizguine. Population pharmacokinetics of ganciclovir and valganciclovir in paediatric solid organ and stem cell transplant recipients.
British journal of clinical pharmacology.
2021 08; 87(8):3105-3114. doi:
10.1111/bcp.14719
. [PMID: 33373493] - Juulia Räihä, Fernanda Ortiz, Laura Mannonen, Raisa Loginov, Marko Lempinen, Irmeli Lautenschlager, Ilkka Helanterä. The burden of cytomegalovirus infection remains high in high-risk kidney transplant recipients despite six-month valganciclovir prophylaxis.
Transplant infectious disease : an official journal of the Transplantation Society.
2021 Aug; 23(4):e13577. doi:
10.1111/tid.13577
. [PMID: 33527660] - Isabel Rodríguez-Goncer, María Ruiz-Ruigómez, Francisco López-Medrano, Laura Corbella, Natalia Polanco, Esther González Monte, Rafael San Juan, Tamara Ruiz-Merlo, Patricia Parra, Lola Folgueira, Amado Andrés, José María Aguado, Mario Fernández-Ruiz. CMV infection, valganciclovir exposure, and the risk of BK viremia and associated nephropathy after kidney transplantation: Is there a link?.
Transplant infectious disease : an official journal of the Transplantation Society.
2021 Aug; 23(4):e13597. doi:
10.1111/tid.13597
. [PMID: 33751753] - Margaret R Jorgenson, Jillian L Descourouez, Neetika Garg, Sandesh Parajuli, Didier A Mandelbrot, Jon S Odorico, Christopher M Saddler, Jeannina A Smith. The addition of adjunctive letermovir to valganciclovir for refractory cytomegalovirus viremia in kidney transplant recipients.
Transplant infectious disease : an official journal of the Transplantation Society.
2021 Aug; 23(4):e13693. doi:
10.1111/tid.13693
. [PMID: 34309158] - Jin Ho Lee, Heeryong Lee, Seoung Woo Lee, Seun Deuk Hwang, Joon Ho Song. Efficacy and Safety According to the Dose of Valganciclovir for Cytomegalovirus Prophylaxis in Transplantation: Network Meta-analysis Using Recent Data.
Transplantation proceedings.
2021 Jul; 53(6):1945-1950. doi:
10.1016/j.transproceed.2021.05.006
. [PMID: 34253379] - Andrew S Jarrell, Jessica R Crow, Sara E Strout, Rachel M Kruer, Lindsey P Toman, Maria V Dioverti-Prono, Laura Lees, Robin K Avery, Mark A Marzinke. Valganciclovir Dosing for Cytomegalovirus Prophylaxis in Solid-organ Transplant Recipients on Continuous Veno-venous Hemodialysis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2021 07; 73(1):101-106. doi:
10.1093/cid/ciaa537
. [PMID: 32379860] - Jorge Andrade-Sierra, Alejandro Heredia-Pimentel, Enrique Rojas-Campos, Diana Ramírez Flores, José I Cerrillos-Gutierrez, Alejandra G Miranda-Díaz, Luis A Evangelista-Carrillo, Petra Martínez-Martínez, Basilio Jalomo-Martínez, Eduardo Gonzalez-Espinoza, Benjamin Gómez-Navarro, Miguel Medina-Pérez, Juan José Nieves-Hernández. Cytomegalovirus in renal transplant recipients from living donors with and without valganciclovir prophylaxis and with immunosuppression based on anti-thymocyte globulin or basiliximab.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
2021 Jun; 107(?):18-24. doi:
10.1016/j.ijid.2021.04.032
. [PMID: 33862205] - Takaya Iida, Kenichiro Miura, Hideki Ban, Taro Ando, Yoko Shirai, Sho Ishiwa, Atsutoshi Shiratori, Naoto Kaneko, Tomoo Yabuuchi, Kiyonobu Ishizuka, Masanori Takaiwa, Kazuhide Suyama, Masataka Hisano, Motoshi Hattori. Valganciclovir prophylaxis for cytomegalovirus infection in pediatric kidney transplant recipients: a single-center experience.
Clinical and experimental nephrology.
2021 May; 25(5):531-536. doi:
10.1007/s10157-021-02020-z
. [PMID: 33506359] - Kamal Masarweh, Clari Felszer-Fisch, Eric Shinwell, Jamal Hasanein, Marina Peniakov, Scott A Weiner, Bella Lurye-Marcu, Dan Miron. The Yield of Targeted Examination for the Detection of Symptomatic Congenital Cytomegalovirus Infection.
The Israel Medical Association journal : IMAJ.
2021 May; 23(5):318-322. doi:
NULL
. [PMID: 34024050] - Rachel Hellemans, Veerle Wijtvliet, Kristof Bergs, Ester Philipse, Rowena Vleut, Annick Massart, Marie-Madeleine Couttenye, Veerle Matheeussen, Daniel Abramowicz. A split strategy to prevent cytomegalovirus after kidney transplantation using prophylaxis in serological high-risk patients and a pre-emptive strategy in intermediate-risk patients: Combining the best of two options?.
Transplant infectious disease : an official journal of the Transplantation Society.
2021 Apr; 23(2):e13467. doi:
10.1111/tid.13467
. [PMID: 32935909] - Amit D Raval, Kristin D Kistler, Yuexin Tang, Yoshihiko Murata, David R Snydman. Epidemiology, risk factors, and outcomes associated with cytomegalovirus in adult kidney transplant recipients: A systematic literature review of real-world evidence.
Transplant infectious disease : an official journal of the Transplantation Society.
2021 Apr; 23(2):e13483. doi:
10.1111/tid.13483
. [PMID: 33012092] - Bing Chen, Shan-Shan Hu, Wen-Bin Rui, Hui-Min An, Xiao-Hui Zhai, Xi-Han Wang, Jia-Qian Lu, Kun Shao, Pei-Jun Zhou. Population Pharmacokinetics and Bayesian Estimation of the Area Under the Concentration-Time Curve for Ganciclovir in Adult Chinese Renal Allograft Recipients After Valganciclovir Administration.
Journal of clinical pharmacology.
2021 03; 61(3):328-338. doi:
10.1002/jcph.1735
. [PMID: 32926418] - Joanna Schaenman, Korntip Phonphok, Ittikorn Spanuchart, Tin Duong, Theodore M Sievers, Erik Lum, Elaine F Reed, Suphamai Bunnapradist. Early cytomegalovirus DNAemia and antiviral dose adjustment in high vs intermediate risk kidney transplant recipients.
Transplant infectious disease : an official journal of the Transplantation Society.
2021 Feb; 23(1):e13457. doi:
10.1111/tid.13457
. [PMID: 32892447] - Eisuke Suganuma, Hideaki Sakata, Nodoka Adachi, Satoshi Asanuma, Mihoko Furuichi, Yoji Uejima, Satoshi Sato, Tomoya Abe, Daigo Matsumoto, Ryohei Takahashi, Sachi Yamamoto, Yutaka Kawano, Takashi Arai, Tsutomu Oh-Ishi. Efficacy, safety, and pharmacokinetics of oral valganciclovir in patients with congenital cytomegalovirus infection.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2021 Feb; 27(2):185-191. doi:
10.1016/j.jiac.2020.08.019
. [PMID: 32907793] - Pascale Mazzola, Elke Schaeffeler, Oliver Witzke, Martin Nitschke, Volker Kliem, Max Zortel, Eva-Maria Wagner, Matthias Schwab, Ingeborg A Hauser. No association of genetic variants in TLR4, TNF-α, IL10, IFN-γ, and IL37 in cytomegalovirus-positive renal allograft recipients with active CMV infection-Subanalysis of the prospective randomised VIPP study.
PloS one.
2021; 16(4):e0246118. doi:
10.1371/journal.pone.0246118
. [PMID: 33861738] - Marlene Plüß, Kemal Mese, Johannes T Kowallick, Andreas Schuster, Désirée Tampe, Björn Tampe. Case Report: Cytomegalovirus Reactivation and Pericarditis Following ChAdOx1 nCoV-19 Vaccination Against SARS-CoV-2.
Frontiers in immunology.
2021; 12(?):784145. doi:
10.3389/fimmu.2021.784145
. [PMID: 35116025] - Yu-Jhou Chen, Hsin-Chih Huang, Tse-Ching Chen, Hao-Tsai Cheng. Cytomegalovirus esophagitis with symptoms of gastroesophageal reflux disease in a kidney transplant recipient.
The Kaohsiung journal of medical sciences.
2020 Oct; 36(10):859-860. doi:
10.1002/kjm2.12264
. [PMID: 32671960] - Dominika Jedlińska-Pijanowska, Justyna Czech-Kowalska, Magdalena Kłodzińska, Aleksandra Pietrzyk, Eliza Michalska, Kinga Gradowska, Anna Dobrzańska, Beata Kasztelewicz, Dariusz Gruszfeld. Antiviral treatment in congenital HCMV infection: The six-year experience of a single neonatal center in Poland.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University.
2020 10; 29(10):1161-1167. doi:
10.17219/acem/125427
. [PMID: 33053275] - Steffen Jockusch, Chuanjuan Tao, Xiaoxu Li, Thomas K Anderson, Minchen Chien, Shiv Kumar, James J Russo, Robert N Kirchdoerfer, Jingyue Ju. A library of nucleotide analogues terminate RNA synthesis catalyzed by polymerases of coronaviruses that cause SARS and COVID-19.
Antiviral research.
2020 08; 180(?):104857. doi:
10.1016/j.antiviral.2020.104857
. [PMID: 32562705] - Hideto Yamada, Kenji Tanimura, Sachiyo Fukushima, Kazumichi Fujioka, Masashi Deguchi, Yuki Sasagawa, Shinya Tairaku, Toru Funakoshi, Ichiro Morioka. A cohort study of the universal neonatal urine screening for congenital cytomegalovirus infection.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2020 Aug; 26(8):790-794. doi:
10.1016/j.jiac.2020.03.009
. [PMID: 32273174] - Dominika Klimczak-Tomaniak, Stefan Roest, Jasper J Brugts, Kadir Caliskan, Isabella Kardys, Felix Zijlstra, Alina A Constantinescu, Jolanda J C Voermans, Jeroen J A van Kampen, Olivier C Manintveld. The Association Between Cytomegalovirus Infection and Cardiac Allograft Vasculopathy in the Era of Antiviral Valganciclovir Prophylaxis.
Transplantation.
2020 07; 104(7):1508-1518. doi:
10.1097/tp.0000000000003015
. [PMID: 31644496] - Hannah Imlay, Allison O Dumitriu Carcoana, Cynthia E Fisher, Beatrice Wong, Robert M Rakita, Daniel P Fishbein, Ajit P Limaye. Impact of valganciclovir prophylaxis duration on cytomegalovirus disease in high-risk donor seropositive/recipient seronegative heart transplant recipients.
Transplant infectious disease : an official journal of the Transplantation Society.
2020 Jun; 22(3):e13255. doi:
10.1111/tid.13255
. [PMID: 32020736] - Melissa R Laub, Jennifer Byrns, Jennifer Gommer, Matthew Ellis, Matt Harris. Delayed vs initial cytomegalovirus prophylaxis after kidney transplantation.
Clinical transplantation.
2020 06; 34(6):e13854. doi:
10.1111/ctr.13854
. [PMID: 32163619] - Joseph E Rower, Chris Nielson, Kevin Shi, Albert H Park. Validation of an assay for quantifying ganciclovir in dried blood spots.
Journal of pharmaceutical and biomedical analysis.
2020 May; 184(?):113181. doi:
10.1016/j.jpba.2020.113181
. [PMID: 32105943] - Nina Singh, Drew J Winston, Raymund R Razonable, G Marshall Lyon, Fernanda P Silveira, Marilyn M Wagener, Terry Stevens-Ayers, Bradley Edmison, Michael Boeckh, Ajit P Limaye. Effect of Preemptive Therapy vs Antiviral Prophylaxis on Cytomegalovirus Disease in Seronegative Liver Transplant Recipients With Seropositive Donors: A Randomized Clinical Trial.
JAMA.
2020 04; 323(14):1378-1387. doi:
10.1001/jama.2020.3138
. [PMID: 32286644] - Cecilia Botti, Silvia Palma, Maria Federica Roversi, Daniele Monzani, Alberto Berardi, Elisabetta Genovese. Different Audiologic Outcomes in Twins with Congenital Cytomegalovirus Infection.
The journal of international advanced otology.
2020 Apr; 16(1):130-133. doi:
10.5152/iao.2020.6574
. [PMID: 32209524] - Ichiro Morioka, Yasumasa Kakei, Takashi Omori, Kandai Nozu, Kazumichi Fujioka, Tetsushi Yoshikawa, Hiroyuki Moriuchi, Yoshinori Ito, Akira Oka. Efficacy and safety of valganciclovir in patients with symptomatic congenital cytomegalovirus disease: Study Protocol Clinical Trial (SPIRIT Compliant).
Medicine.
2020 Apr; 99(17):e19765. doi:
10.1097/md.0000000000019765
. [PMID: 32332615] - Patrick McLeroth, Darius A Paduch, Markus Abt, Richard Hughes, Suzanne Moore, Nadejda Mudie. Effects of valganciclovir on spermatogenesis in renal transplant patients - results of a multicenter prospective nonrandomized study.
Transplant international : official journal of the European Society for Organ Transplantation.
2020 03; 33(3):310-320. doi:
10.1111/tri.13558
. [PMID: 31729770] - Maria O López-Oliva, Virginia Martínez, Aranzazu Rodríguez-Sanz, Laura Álvarez, M José Santana, Rafael Selgas, Carlos Jiménez, Teresa Bellón. Pre-transplant assessment of pp65-specific CD4 T cell responses identifies CMV-seropositive patients treated with rATG at risk of late onset infection.
Clinical immunology (Orlando, Fla.).
2020 02; 211(?):108329. doi:
10.1016/j.clim.2019.108329
. [PMID: 31891764] - Andrea Ronchi, Fiker Zeray, Lizette E Lee, Kris E Owen, Angela G Shoup, Fabiana Garcia, Liliana N Vazquez, Joseph B Cantey, Shawn Varghese, Lorenza Pugni, Fabio Mosca, Pablo J Sánchez. Evaluation of clinically asymptomatic high risk infants with congenital cytomegalovirus infection.
Journal of perinatology : official journal of the California Perinatal Association.
2020 01; 40(1):89-96. doi:
10.1038/s41372-019-0501-z
. [PMID: 31575999] - Mehdi Maanaoui, Rémi Lenain, Amandine Ydée, Marine Vantriempont, Marc Hazzan. BK polyomavirus and valganciclovir: Evidence is still lacking.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
2019 12; 19(12):3432-3433. doi:
10.1111/ajt.15562
. [PMID: 31400049] - Nikolina Basic-Jukic, Vesna Furic-Cunko, Tvrtko Hudolin, Zoran Zimak, Jason Kirincich, Zeljko Kastelan. A Comparison of Different Valgancyclovir Formulations in the Universal 6-Month Prophylaxis Against CMV Infection in Renal Transplant Recipients: A Randomized Single-Centre Study.
Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki).
2019 Dec; 40(3):47-55. doi:
10.2478/prilozi-2020-0004
. [PMID: 32109215] - Po Yee Mia Leung, Thomas Tran, Adam Testro, Kathy Paizis, Jason Kwong, John B Whitlam. Ganciclovir-resistant post-transplant cytomegalovirus infection due to combined deletion mutation at codons 595-596 of the UL97 gene.
Transplant infectious disease : an official journal of the Transplantation Society.
2019 Dec; 21(6):e13168. doi:
10.1111/tid.13168
. [PMID: 31498954] - Maria Aurora Posadas Salas, Jennifer Thompson, Manish Kadian, Tue Ngo, Evelyn Bruner, Sally Self. Cytomegalovirus renal infection: Rare manifestation of a common post-transplant viral infection-A case series.
Transplant infectious disease : an official journal of the Transplantation Society.
2019 Dec; 21(6):e13169. doi:
10.1111/tid.13169
. [PMID: 31498951] - Bradley J Gardiner, Jennifer K Chow, Samuel L Brilleman, Anton Y Peleg, David R Snydman. The impact of recurrent cytomegalovirus infection on long-term survival in solid organ transplant recipients.
Transplant infectious disease : an official journal of the Transplantation Society.
2019 Dec; 21(6):e13189. doi:
10.1111/tid.13189
. [PMID: 31581352] - Lakshmi Ganapathi, Jennifer Blumenthal, Laila Alawdah, Lynne Lewis, Jennifer Gilarde, Sarah Jones, Carly Milliren, Heung Bae Kim, Tanvi S Sharma. Impact of standardized protocols for cytomegalovirus disease prevention in pediatric solid organ transplant recipients.
Pediatric transplantation.
2019 11; 23(7):e13568. doi:
10.1111/petr.13568
. [PMID: 31515909] - Katie Korneffel, Graham Mitro, Kellie Buschor, Michael Rees, Jorge Ortiz. Low dose valganciclovir as cytomegalovirus prophylaxis in post-renal transplant recipients induced with alemtuzumab: A single-center study.
Transplant immunology.
2019 10; 56(?):101226. doi:
10.1016/j.trim.2019.101226
. [PMID: 31344441] - Jin Ho Lee, Hee Yeoun Kim, Dong Yeol Lee, Yoon Ji Kim, Hee Ryong Lee, Joon Seok Oh, Yong Hun Sin, Joong Kyung Kim, Seun Deuk Hwang. Efficacy and Safety of Ultra-Low-Dose Valganciclovir Chemoprophylaxis for Cytomegalovirus Infection in High-Risk Kidney Transplantation Patients.
Transplantation proceedings.
2019 Oct; 51(8):2689-2692. doi:
10.1016/j.transproceed.2019.04.078
. [PMID: 31351773] - Johan Maertens, Catherine Cordonnier, Peter Jaksch, Xavier Poiré, Marc Uknis, Jingyang Wu, Anna Wijatyk, Faouzi Saliba, Oliver Witzke, Stephen Villano. Maribavir for Preemptive Treatment of Cytomegalovirus Reactivation.
The New England journal of medicine.
2019 09; 381(12):1136-1147. doi:
10.1056/nejmoa1714656
. [PMID: 31532960] - Tomas Reischig, Martin Kacer, Ondrej Hes, Jana Machova, Jana Nemcova, Daniel Lysak, Pavel Jindra, Kristyna Pivovarcikova, Stanislav Kormunda, Mirko Bouda. Cytomegalovirus prevention strategies and the risk of BK polyomavirus viremia and nephropathy.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
2019 09; 19(9):2457-2467. doi:
10.1111/ajt.15507
. [PMID: 31220412] - Brandon Chatani, Wendy Glaberson, Zsuzsanna Nemeth, Leonardo Tamariz, Ivan A Gonzalez. GCV/VCVG prophylaxis against CMV DNAemia in pediatric renal transplant patients: A systematic review and meta-analysis.
Pediatric transplantation.
2019 09; 23(6):e13514. doi:
10.1111/petr.13514
. [PMID: 31210393] - Adi Pappo, Orit Peled, Matitiahu Berkovitch, Efraim Bilavsky, Eran Rom, Jacob Amir, Irit Krause, Havatzelet Yarden-Bilavsky, Oded Scheuerman, Liat Ashkenazi-Hoffnung. Efficacy and Safety of a Weight-based Dosing Regimen of Valganciclovir for Cytomegalovirus Prophylaxis in Pediatric Solid-organ Transplant Recipients.
Transplantation.
2019 08; 103(8):1730-1735. doi:
10.1097/tp.0000000000002632
. [PMID: 31343571] - Sari R Freedman, Bharath R Ravichandran, Brian M Masters, Jonathan S Bromberg, Abdolreza Haririan, Kapil K Saharia, Emily L Heil, Tracy Sparkes. Clinical outcomes of valganciclovir prophylaxis in high-risk (D+/R-) renal transplant recipients experiencing delayed graft function.
Transplant infectious disease : an official journal of the Transplantation Society.
2019 Aug; 21(4):e13125. doi:
10.1111/tid.13125
. [PMID: 31165548] - Conrad Rauber, Katja Bartelheimer, Taotao Zhou, Christian Rupp, Paul Schnitzler, Peter Schemmer, Peter Sauer, Karl Heinz Weiss, Daniel Nils Gotthardt. Prevalence of human herpesviruses in biliary fluid and their association with biliary complications after liver transplantation.
BMC gastroenterology.
2019 Jun; 19(1):110. doi:
10.1186/s12876-019-1033-x
. [PMID: 31248389] - Medhat A Halim, Osama A Gheith, Yahya Makkeya, Ayman M Nagib, Ahmed F Atta, Mohamed Emam, Ahmed Yehia, Tarek Said, Prasad Nair, Torki Al-Otaibi. Extended Efficacy of Low-Dose Valganciclovir for Prevention of Cytomegalovirus Disease in Intermediate-Risk Kidney Transplant Recipients: Two-Year Follow-Up.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.
2019 06; 17(3):339-343. doi:
10.6002/ect.2018.0020
. [PMID: 30674240] - Medhini Boteju, Praveen Weeratunga, Ahalyaa Sivashangar, Thashi Chang. Cytomegalovirus induced refractory TTP in an immunocompetent individual: a case report.
BMC infectious diseases.
2019 May; 19(1):394. doi:
10.1186/s12879-019-4037-9
. [PMID: 31068128] - Wen-Bin Rui, Hui-Min An, Kun Shao, Xiao-Hui Zhai, Jia-Qian Lu, Shan-Shan Hu, Bing Chen, Pei-Jun Zhou. Limited sampling strategy for the estimation of the area under the concentration-time curve for ganciclovir in Chinese adult renal allograft recipients.
European journal of clinical pharmacology.
2019 May; 75(5):677-686. doi:
10.1007/s00228-018-02613-w
. [PMID: 30643927] - Grant Paulsen, Pia Cumagun, Emily Mixon, Karen Fowler, Daniel Feig, Masako Shimamura. Cytomegalovirus and Epstein-Barr virus infections among pediatric kidney transplant recipients at a center using universal Valganciclovir Prophylaxis.
Pediatric transplantation.
2019 05; 23(3):e13382. doi:
10.1111/petr.13382
. [PMID: 30786115] - Sheila Lumley, Cameron Green, Hannah Rafferty, Colette Smith, Mark Harber, James O'Beirne, Gareth Jones, Douglas Thorburn, Aileen Marshall, Tina Shah, Mohamed Zuhair, Emily Rothwell, Sowsan Atabani, Tanzina Haque, Paul Griffiths. Cytomegalovirus viral load parameters associated with earlier initiation of pre-emptive therapy after solid organ transplantation.
PloS one.
2019; 14(1):e0210420. doi:
10.1371/journal.pone.0210420
. [PMID: 30682032] - Lauren Cherrier, Aasya Nasar, Kellie J Goodlet, Michael D Nailor, Sofya Tokman, Sunwen Chou. Emergence of letermovir resistance in a lung transplant recipient with ganciclovir-resistant cytomegalovirus infection.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
2018 12; 18(12):3060-3064. doi:
10.1111/ajt.15135
. [PMID: 30286286] - Eisuke Suganuma, Akira Oka, Hideaki Sakata, Nodoka Adachi, Satoshi Asanuma, Eiji Oguma, Akira Yamaguchi, Mihoko Furuichi, Yoji Uejima, Satoshi Sato, Tadamasa Takano, Yutaka Kawano, Risa Tanaka, Takashi Arai, Tsutomu Oh-Ishi. 10-year follow-up of congenital cytomegalovirus infection complicated with severe neurological findings in infancy: a case report.
BMC pediatrics.
2018 11; 18(1):369. doi:
10.1186/s12887-018-1348-8
. [PMID: 30470211] - Tomas Reischig, Martin Kacer, Petra Hruba, Hana Hermanova, Ondrej Hes, Daniel Lysak, Stanislav Kormunda, Mirko Bouda. Less renal allograft fibrosis with valganciclovir prophylaxis for cytomegalovirus compared to high-dose valacyclovir: a parallel group, open-label, randomized controlled trial.
BMC infectious diseases.
2018 Nov; 18(1):573. doi:
10.1186/s12879-018-3493-y
. [PMID: 30442095] - Thomas Tängdén, Pier Giorgio Cojutti, Jason A Roberts, Federico Pea. Valganciclovir Pharmacokinetics in Patients Receiving Oral Prophylaxis Following Kidney Transplantation and Model-Based Predictions of Optimal Dosing Regimens.
Clinical pharmacokinetics.
2018 11; 57(11):1399-1405. doi:
10.1007/s40262-018-0638-5
. [PMID: 29546589] - J H Lee, S D Hwang, J H Song, J H Kim, H Y Kim, D Y Lee, J S Oh, Y H Sin, J K Kim. Efficacy of Ultralow-Dose Valganciclovir Chemoprophylaxis for Cytomegalovirus Infection in ABO-Incompatible Kidney Transplantation Recipients.
Transplantation proceedings.
2018 Oct; 50(8):2485-2488. doi:
10.1016/j.transproceed.2018.04.010
. [PMID: 30241930] - S D Hwang, J H Lee, S W Lee, J K Kim, M-J Kim, J H Song. Effect of Low-Dose Vs Standard-Dose Valganciclovir in the Prevention of Cytomegalovirus Disease in Kidney Transplantation Recipients: A Systemic Review and Meta-Analysis.
Transplantation proceedings.
2018 Oct; 50(8):2473-2478. doi:
10.1016/j.transproceed.2018.01.023
. [PMID: 29871773] - Gurinder Kumar, Mohammed Khair Al Ghabra, Sadia Hafez Ilyas, Vasudev Omprakash Sharma, Naser Al Zein, Eihab Al Khasawneh. Submandibular lymphadenopathy in a child post-renal transplant-'What lies beneath?!': Questions.
Pediatric nephrology (Berlin, Germany).
2018 09; 33(9):1509-1510. doi:
10.1007/s00467-017-3859-1
. [PMID: 29368098] - Ignacio A Echenique, Michael P Angarone, Jonathan D Rich, Allen S Anderson, Valentina Stosor. Cytomegalovirus infection in heart transplantation: A single center experience.
Transplant infectious disease : an official journal of the Transplantation Society.
2018 Aug; 20(4):e12896. doi:
10.1111/tid.12896
. [PMID: 29602266] - Oliver Witzke, Martin Nitschke, Michael Bartels, Heiner Wolters, Gunter Wolf, Petra Reinke, Ingeborg A Hauser, Ulrich Alshuth, Volker Kliem. Valganciclovir Prophylaxis Versus Preemptive Therapy in Cytomegalovirus-Positive Renal Allograft Recipients: Long-term Results After 7 Years of a Randomized Clinical Trial.
Transplantation.
2018 05; 102(5):876-882. doi:
10.1097/tp.0000000000002024
. [PMID: 29166336] - Dominika Deborska-Materkowska, Agnieszka Perkowska-Ptasinska, Anna Sadowska, Jolanta Gozdowska, Michał Ciszek, Marta Serwanska-Swietek, Piotr Domagala, Dorota Miszewska-Szyszkowska, Elzbieta Sitarek, Agnieszka Jozwik, Artur Kwiatkowski, Magdalena Durlik. Diagnostic utility of monitoring cytomegalovirus-specific immunity by QuantiFERON-cytomegalovirus assay in kidney transplant recipients.
BMC infectious diseases.
2018 04; 18(1):179. doi:
10.1186/s12879-018-3075-z
. [PMID: 29661141] - David Hensler, Chad L Richardson, Joslyn Brown, Christine Tseng, Phyllis J DeCamp, Amy Yang, Anna Pawlowski, Bing Ho, Michael G Ison. Impact of electronic health record-based, pharmacist-driven valganciclovir dose optimization in solid organ transplant recipients.
Transplant infectious disease : an official journal of the Transplantation Society.
2018 Apr; 20(2):e12849. doi:
10.1111/tid.12849
. [PMID: 29360250] - Amy W Liu, Kamonwan Jutivorakool, Cynthia E Fisher, Robert M Rakita, Jorge D Reyes, Renuka B Bhattacharya, Keith R Jerome, Ajit P Limaye. Comparison of Preemptive Therapy and Antiviral Prophylaxis for Prevention of Cytomegalovirus in Seropositive Liver Transplant Recipients.
Transplantation.
2018 04; 102(4):632-639. doi:
10.1097/tp.0000000000002029
. [PMID: 29215460] - M Cintra-Cabrera, A Suárez-Benjumea, G Bernal-Blanco, F M González-Roncero, N G Toapanta-Gaibor, M Súñer-Poblet, M Á Pérez-Valdivia, F Fernández-Cuenca, M Á Gentil-Govantes, J L Rocha-Castilla. Resistant Cytomegalovirus Infection After Renal Transplantation: Literature Review.
Transplantation proceedings.
2018 Mar; 50(2):575-577. doi:
10.1016/j.transproceed.2017.09.058
. [PMID: 29579856] - Johan Noble, Philippe Gatault, Bénédicte Sautenet, Catherine Gaudy-Graffin, Agnes Beby-Defaux, Antoine Thierry, Marie Essig, Jean-Michel Halimi, Eliza Munteanu, Sophie Alain, Matthias Buchler. Predictive factors of spontaneous CMV DNAemia clearance in kidney transplantation.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.
2018 Feb; 99-100(?):38-43. doi:
10.1016/j.jcv.2017.12.011
. [PMID: 29306112] - Clarisse Grèze, Cyril Garrouste, Jean-Louis Kemeny, Carole Philipponnet, Julien Aniort, Anne-Élisabeth Heng. [Collapsing focal segmental glomerulosclerosis induced by cytomegalovirus: A case report].
Nephrologie & therapeutique.
2018 Feb; 14(1):50-53. doi:
10.1016/j.nephro.2017.06.002
. [PMID: 29191574] - K Nanmoku, T Shinzato, T Kubo, T Shimizu, T Kimura, T Yagisawa. Prevention of Late-Onset Cytomegalovirus Infection and Disease in Donor-Positive/Recipient-Negative Kidney Transplant Recipients Using Low-Dose Valganciclovir.
Transplantation proceedings.
2018 Jan; 50(1):124-129. doi:
10.1016/j.transproceed.2017.12.025
. [PMID: 29407294] - Rehan Rajput, Alastair K Denniston, Philip I Murray. False Negative Toxoplasma Serology in an Immunocompromised Patient with PCR Positive Ocular Toxoplasmosis.
Ocular immunology and inflammation.
2018; 26(8):1200-1202. doi:
10.1080/09273948.2017.1332769
. [PMID: 28700250] - K M Baradhi, R L Aure, J-M El-Amm. High-dose Valganciclovir Treatment for Resistant Cytomegalovirus Colitis due to UL97 and UL54 Mutations.
Transplantation proceedings.
2018 Jan; 50(1):142-144. doi:
10.1016/j.transproceed.2017.11.013
. [PMID: 29407298] - James N Fleming, David J Taber, Nicole A Weimert, Satish Nadig, John W McGillicuddy, Charles F Bratton, Prabhakar K Baliga, Kenneth D Chavin. Valganciclovir (VGCV) followed by cytomegalovirus (CMV) hyperimmune globulin compared to VGCV for 200 days in abdominal organ transplant recipients at high risk for CMV infection: A prospective, randomized pilot study.
Transplant infectious disease : an official journal of the Transplantation Society.
2017 Dec; 19(6):. doi:
10.1111/tid.12779
. [PMID: 28921781] - Salman Khan, Clara Fischman, Shirish Huprikar. Low-dose valganciclovir prophylaxis for cytomegalovirus in intermediate-risk (R+) renal transplant recipients: Single-center experience.
Transplant infectious disease : an official journal of the Transplantation Society.
2017 Dec; 19(6):. doi:
10.1111/tid.12780
. [PMID: 28940831] - Elda Righi, Alessia Carnelutti, Daniele Muser, Francesco Zaja, Elisa Lucchini, Federico Pea, Fernando Di Gregorio, Abass Alavi, Matteo Bassetti. Successful treatment and FDG-PET/CT monitoring of HHV-6 encephalitis in a non-neutropenic patient: case report and literature review.
Journal of neurovirology.
2017 12; 23(6):908-912. doi:
10.1007/s13365-017-0566-4
. [PMID: 28822107] - F Halleck, D Khadzhynov, E Schrezenmeier, L Lehner, K Budde, O Staeck. Prolonged Low-Dose Prophylaxis With Valganciclovir in Cytomegalovirus-Negative Recipients of Kidney Transplants From Cytomegalovirus-Positive Donors Allows Seroconversion and Prevents Cytomegalovirus Disease.
Transplantation proceedings.
2017 Dec; 49(10):2280-2284. doi:
10.1016/j.transproceed.2017.10.004
. [PMID: 29198661] - Bradley J Gardiner, Jennifer K Chow, Lori Lyn Price, Natalie E Nierenberg, David M Kent, David R Snydman. Role of Secondary Prophylaxis With Valganciclovir in the Prevention of Recurrent Cytomegalovirus Disease in Solid Organ Transplant Recipients.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2017 Nov; 65(12):2000-2007. doi:
10.1093/cid/cix696
. [PMID: 29020220] - María Ovidia López-Oliva, Julio Flores, Rosario Madero, Fernando Escuin, María José Santana, Teresa Bellón, Rafael Selgas, Carlos Jiménez. Cytomegalovirus infection after kidney transplantation and long-term graft loss.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia.
2017 Sep; 37(5):515-525. doi:
10.1016/j.nefro.2016.11.018
. [PMID: 28946964] - Ajit P Limaye, Renee D Stapleton, Lili Peng, Scott R Gunn, Louise E Kimball, Robert Hyzy, Matthew C Exline, D Clark Files, Peter E Morris, Stephen K Frankel, Mark E Mikkelsen, Duncan Hite, Kyle B Enfield, Jay Steingrub, James O'Brien, Polly E Parsons, Joseph Cuschieri, Richard G Wunderink, David L Hotchkin, Ying Q Chen, Gordon D Rubenfeld, Michael Boeckh. Effect of Ganciclovir on IL-6 Levels Among Cytomegalovirus-Seropositive Adults With Critical Illness: A Randomized Clinical Trial.
JAMA.
2017 08; 318(8):731-740. doi:
10.1001/jama.2017.10569
. [PMID: 28829877] - O Kır, A Zeytinoğlu, B Arda, M Yılmaz, G Aşçı, H Töz. Impact of Prophylaxis vs Pre-emptive Approach for Cytomegalovirus Infection in Kidney Transplant Recipients.
Transplantation proceedings.
2017 Apr; 49(3):537-540. doi:
10.1016/j.transproceed.2017.01.027
. [PMID: 28340829] - G Varela-Fascinetto, C Benchimol, R Reyes-Acevedo, M Genevray, D Bradley, J Ives, H T Silva. Tolerability of up to 200 days of prophylaxis with valganciclovir oral solution and/or film-coated tablets in pediatric kidney transplant recipients at risk of cytomegalovirus disease.
Pediatric transplantation.
2017 Feb; 21(1):. doi:
10.1111/petr.12833
. [PMID: 27753183] - Bernadette M Cameron, Sean E Kennedy, William D Rawlinson, Fiona E Mackie. The efficacy of valganciclovir for prevention of infections with cytomegalovirus and Epstein-Barr virus after kidney transplant in children.
Pediatric transplantation.
2017 Feb; 21(1):. doi:
10.1111/petr.12816
. [PMID: 27704725] - Osama Gheith, Medhat A Halim, Torki Al-Otaibi, Hany Mansour, Ahmed Mosaad, Hassanein Abo Atteya, Zakaria Zakaria, Tarek Said, Prasad Nair, Narayanam Nampoory. Successful Cost-Effective Prevention of Cytomegalovirus Disease in Kidney Transplant Recipients Using Low-Dose Valganciclovir.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.
2017 Feb; 15(Suppl 1):156-163. doi:
10.6002/ect.mesot2016.p34
. [PMID: 28260458] - Wang Xin, Yang Hui, Zhang Xiaodong, Cui Xiangli, Wang Shihui, Liu Lihong. Effectiveness of Valganciclovir 900mg Versus 450mg for Cytomegalovirus Prophylaxis in Renal Transplantation: A Systematic Review and Meta-Analysis.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.
2017; 20(0):168-183. doi:
10.18433/j3805b
. [PMID: 28719361] - Željka Večerić-Haler, Boštjan Bizjak, Karmen Romozi, Miha Arnol. Expanded valganciclovir prophylaxis in kidney transplant recipients is associated with lower incidence of cytomegalovirus infection.
Clinical nephrology.
2017 Sup; 88(13):126-130. doi:
10.5414/cnp88fx27
. [PMID: 28601128] - Seth Heldenbrand, Chenghui Li, Rosemary P Cross, Kelly A DePiero, Travis B Dick, Kara Ferguson, Miae Kim, Erin Newkirk, Jeong M Park, Janice Sudaria-Kerr, Eric M Tichy, Kimi R Ueda, Renee Weng, Jesse Wisniewski, Steven Gabardi. Multicenter evaluation of efficacy and safety of low-dose versus high-dose valganciclovir for prevention of cytomegalovirus disease in donor and recipient positive (D+/R+) renal transplant recipients.
Transplant infectious disease : an official journal of the Transplantation Society.
2016 Dec; 18(6):904-912. doi:
10.1111/tid.12609
. [PMID: 27639246] - Denise Bradley, Sebastian Moreira, Vishak Subramoney, Clifford Chin, Jane Ives, Ka Wang. Pharmacokinetics and Safety of Valganciclovir in Pediatric Heart Transplant Recipients 4 Months of Age and Younger.
The Pediatric infectious disease journal.
2016 12; 35(12):1324-1328. doi:
10.1097/inf.0000000000001317
. [PMID: 27580058] - V Lukacova, P Goelzer, M Reddy, G Greig, B Reigner, N Parrott. A Physiologically Based Pharmacokinetic Model for Ganciclovir and Its Prodrug Valganciclovir in Adults and Children.
The AAPS journal.
2016 11; 18(6):1453-1463. doi:
10.1208/s12248-016-9956-4
. [PMID: 27450227] - E Luna, F Caravaca, F Ferreira, N Fernandez, P Martín, M L Vargas, J Saenz de Santamaría, G Garcia Pino, L Azevedo, A Muñoz Sanz. Effect of Cytomegalovirus Infection on Survival of Older Kidney Transplant Patients (D+/R+): Impact of Valganciclovir Prophylaxis Versus Preemptive Therapy.
Transplantation proceedings.
2016 Nov; 48(9):2931-2937. doi:
10.1016/j.transproceed.2016.06.062
. [PMID: 27932110] - Medhat A Halim, Torki Al-Otaibi, Osama Gheith, Hani Adel, Ahmed Mosaad, Abu-Atteya Hasaneen, Zakaria Zakaria, Yahya Makkeya, Tarek Said, Prasad Nair. Efficacy and Safety of Low-Dose Versus Standard-Dose Valganciclovir for Prevention of Cytomegalovirus Disease in Intermediate-Risk Kidney Transplant Recipients.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.
2016 Oct; 14(5):526-534. doi:
10.6002/ect.2015.0305
. [PMID: 27310254]