Dicloxacillin Sodium (BioDeep_00000790286)

   


代谢物信息卡片


Dicloxacillin Sodium

化学式: C19H18Cl2N3NaO6S (509.0191028000001)
中文名称: 双氯西林钠
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].O.[Na+]
InChI: +1

描述信息

D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

同义名列表

2 个代谢物同义名

Dicloxacillin Sodium; Dicloxacillin sodium



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Marcella Muysson, Palika Datta, Kathleen Rewers-Felkins, Teresa Baker, Thomas W Hale. Transfer of Dicloxacillin into Human Milk. Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine. 2020 11; 15(11):715-717. doi: 10.1089/bfm.2020.0156. [PMID: 32678981]
  • Anis Zand Irani, Ahmed Almuwais, Holly Gibbons. Acquired pyroglutamic acidosis due to long-term dicloxacillin and paracetamol use. BMJ case reports. 2020 Apr; 13(4):. doi: 10.1136/bcr-2019-233306. [PMID: 32273269]
  • Aws Alshamsan, Fadilah Sfouq Aleanizy, Mohamed Badran, Fulwah Yahya Alqahtani, Haya Alfassam, Abdulaziz Almalik, Sara Alosaimy. Exploring anti-MRSA activity of chitosan-coated liposomal dicloxacillin. Journal of microbiological methods. 2019 01; 156(?):23-28. doi: 10.1016/j.mimet.2018.11.015. [PMID: 30465793]
  • Tore Bjerregaard Stage, Magnus Graff, Susan Wong, Louise Ladebo Rasmussen, Flemming Nielsen, Anton Pottegård, Kim Brøsen, Deanna L Kroetz, S Cyrus Khojasteh, Per Damkier. Dicloxacillin induces CYP2C19, CYP2C9 and CYP3A4 in vivo and in vitro. British journal of clinical pharmacology. 2018 03; 84(3):510-519. doi: 10.1111/bcp.13467. [PMID: 29105855]
  • Kristian Kraft Hansen, Flemming Nielsen, Tore Bjerregaard Stage, Uffe Jørgensen, Ole Skov, Lasse E Rasmussen. Microdialysis as a tool to determine the local tissue concentration of dicloxacillin in man. British journal of clinical pharmacology. 2018 03; 84(3):533-541. doi: 10.1111/bcp.13468. [PMID: 29105799]
  • Claes Søndergaard Wassmann, Lars Christian Lund, Mette Thorsing, Sabrina Prehn Lauritzen, Hans Jørn Kolmos, Birgitte Haahr Kallipolitis, Janne Kudsk Klitgaard. Molecular mechanisms of thioridazine resistance in Staphylococcus aureus. PloS one. 2018; 13(8):e0201767. doi: 10.1371/journal.pone.0201767. [PMID: 30089175]
  • Elmas Sari, Pawel Berczynski, Aleksandra Kladna, Irena Kruk, Oya Bozdag Dundar, Monika Szymanska, Hassan Y Aboul-Enein. Synthesis and in vitro Antioxidant Activity Study of Some Novel Substituted Piperazinyl Flavone Compounds. Medicinal chemistry (Shariqah (United Arab Emirates)). 2018; 14(4):372-386. doi: 10.2174/1573406414666171204105000. [PMID: 29205120]
  • Sandra Johansson, Ole M Christensen, Anders H Thorsmark. A retrospective study of acute kidney injury in hip arthroplasty patients receiving gentamicin and dicloxacillin. Acta orthopaedica. 2016 Dec; 87(6):589-591. doi: 10.1080/17453674.2016.1231008. [PMID: 27648882]
  • Guolan Wu, Yunliang Zheng, Huili Zhou, Xingjiang Hu, Jian Liu, You Zhai, Meixiang Zhu, Lihua Wu, Jianzhong Shentu. Safety and pharmacokinetics of dicloxacillin in healthy Chinese volunteers following single and multiple oral doses. Drug design, development and therapy. 2015; 9(?):5687-95. doi: 10.2147/dddt.s92117. [PMID: 26527863]
  • Somnath D Bhinge, Sharangouda M Malipatil, Lalit V Sonawane. Bioanalytical method development and validation for simultaneous estimation of cefixime and dicloxacillin by RP-HPLC in human plasma. Acta chimica Slovenica. 2014; 61(3):580-6. doi: NULL. [PMID: 25286213]
  • Anne Sandberg, Sandrine Lemaire, Françoise Van Bambeke, Paul M Tulkens, Diarmaid Hughes, Christof von Eiff, Niels Frimodt-Møller. Intra- and extracellular activities of dicloxacillin and linezolid against a clinical Staphylococcus aureus strain with a small-colony-variant phenotype in an in vitro model of THP-1 macrophages and an in vivo mouse peritonitis model. Antimicrobial agents and chemotherapy. 2011 Apr; 55(4):1443-52. doi: 10.1128/aac.00205-10. [PMID: 21282430]
  • Jack T Rogers, Sohan Mikkilineni, Ippolita Cantuti-Castelvetri, Deborah H Smith, Xudong Huang, Sanghamitra Bandyopadhyay, Catherine M Cahill, Maria L Maccecchini, Debomoy K Lahiri, Nigel H Greig. The alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen. Journal of neural transmission (Vienna, Austria : 1996). 2011 Mar; 118(3):493-507. doi: 10.1007/s00702-010-0513-5. [PMID: 21221670]
  • Satonori Higuchi, Masanori Kobayashi, Yukitaka Yoshikawa, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima, Tsuyoshi Yokoi. IL-4 mediates dicloxacillin-induced liver injury in mice. Toxicology letters. 2011 Feb; 200(3):139-45. doi: 10.1016/j.toxlet.2010.11.006. [PMID: 21094227]
  • Anne Sandberg, Klaus Skovbo Jensen, Pierre Baudoux, Françoise Van Bambeke, Paul M Tulkens, Niels Frimodt-Møller. Intra- and extracellular activities of dicloxacillin against Staphylococcus aureus in vivo and in vitro. Antimicrobial agents and chemotherapy. 2010 Jun; 54(6):2391-400. doi: 10.1128/aac.01400-09. [PMID: 20308386]
  • Paul M Beringer, Jane Kriengkauykiat, Xiyun Zhang, Levita Hidayat, Shanshan Liu, Stan Louie, Tim Synold, Gilbert J Burckart, Purush A Rao, Bertrand Shapiro, Mark Gill. Lack of effect of P-glycoprotein inhibition on renal clearance of dicloxacillin in patients with cystic fibrosis. Pharmacotherapy. 2008 Jul; 28(7):883-94. doi: 10.1592/phco.28.7.883. [PMID: 18576903]
  • Victoria F Samanidou, Evaggelia N Evaggelopoulou, Ioannis N Papadoyannis. Development of a validated HPLC method for the determination of four penicillin antibiotics in pharmaceuticals and human biological fluids. Journal of separation science. 2006 Jul; 29(11):1550-60. doi: 10.1002/jssc.200600081. [PMID: 16922270]
  • Wendy S Putnam, Jonathan M Woo, Yong Huang, Leslie Z Benet. Effect of the MDR1 C3435T variant and P-glycoprotein induction on dicloxacillin pharmacokinetics. Journal of clinical pharmacology. 2005 Apr; 45(4):411-21. doi: 10.1177/0091270004273492. [PMID: 15778422]
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  • Oscar Alderete, Dinora F González-Esquivel, L Misael Del Rivero, Nelly Castro Torres. Liquid chromatographic assay for dicloxacillin in plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2004 Jun; 805(2):353-6. doi: 10.1016/j.jchromb.2004.03.006. [PMID: 15135112]
  • Orjan Friberg, Ian Jones, Lennart Sjöberg, Bo Söderquist, Thomas Vikerfors, Jan Källman. Antibiotic concentrations in serum and wound fluid after local gentamicin or intravenous dicloxacillin prophylaxis in cardiac surgery. Scandinavian journal of infectious diseases. 2003; 35(4):251-4. doi: 10.1080/003655400310000184. [PMID: 12839154]
  • David G Levitt. PKQuest: capillary permeability limitation and plasma protein binding - application to human inulin, dicloxacillin and ceftriaxone pharmacokinetics. BMC clinical pharmacology. 2002 Sep; 2(?):7. doi: 10.1186/1472-6904-2-7. [PMID: 12323078]
  • Robert Skov, Niels Frimodt-Møller, Frank Espersen. In vitro susceptibility of Staphylococcus aureus towards amoxycillin-clavulanic acid, penicillin-clavulanic acid, dicloxacillin and cefuroxime. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 2002 Aug; 110(7-8):559-64. doi: 10.1034/j.1600-0463.2002.11007807.x. [PMID: 12390414]
  • Michael P Sharkey, James B Muir. Staphylococcal scalded skin syndrome complicating acute generalized pustular psoriasis. The Australasian journal of dermatology. 2002 Aug; 43(3):199-201. doi: 10.1046/j.1440-0960.2002.00595.x. [PMID: 12121398]
  • Allan G Jensen, Carsten H Wachmann, Frank Espersen, Jens Scheibel, Peter Skinhøj, Niels Frimodt-Møller. Treatment and outcome of Staphylococcus aureus bacteremia: a prospective study of 278 cases. Archives of internal medicine. 2002 Jan; 162(1):25-32. doi: 10.1001/archinte.162.1.25. [PMID: 11784216]
  • I B Gosbell, J D Turnidge, J W Tapsall, R A Benn. Toxicities of flucloxacillin and dicloxacillin--is there really a difference?. The Medical journal of Australia. 2000 Nov; 173(9):500-1. doi: 10.5694/j.1326-5377.2000.tb139305.x. [PMID: 11149309]
  • P Roncada, L Tomasi, G L Stracciari, L Ermini, A Strocchia. Milk depletion of dicloxacillin residues in cows and sheep following intramammary administration. Journal of veterinary pharmacology and therapeutics. 2000 Aug; 23(4):237-41. doi: 10.1046/j.1365-2885.2000.00257.x. [PMID: 11126324]
  • L Solgaard, J I Tuxoe, M Mafi, S Due Olsen, T Toftgaard Jensen. Nephrotoxicity by dicloxacillin and gentamicin in 163 patients with intertrochanteric hip fractures. International orthopaedics. 2000; 24(3):155-7. doi: 10.1007/s002640000103. [PMID: 10990387]
  • L K Sørensen, L K Snor, T Elkaer, H Hansen. Simultaneous determination of seven penicillins in muscle, liver and kidney tissues from cattle and pigs by a multiresidue high-performance liquid chromatographic method. Journal of chromatography. B, Biomedical sciences and applications. 1999 Nov; 734(2):307-18. doi: 10.1016/s0378-4347(99)00389-8. [PMID: 10595728]
  • I W Boyd. Postmarketing surveillance: strengths and limitations. The flucloxacillin-dicloxacillin story. The Medical journal of Australia. 1999 Aug; 171(4):219. doi: 10.5694/j.1326-5377.1999.tb123611.x. [PMID: 10494242]
  • S L Nielsen, F T Black. Extracellular and intracellular killing in neutrophil granulocytes of Staphylococcus aureus with rifampicin in combination with dicloxacillin or fusidic acid. The Journal of antimicrobial chemotherapy. 1999 Mar; 43(3):407-10. doi: 10.1093/jac/43.3.407. [PMID: 10223598]
  • V K Dhawan, R Nachum, N Bhat, L Tolbert, M Agrawal. Vancomycin-resistant enterococcal colonization in nonhospitalized HIV-infected patients. The Western journal of medicine. 1998 Nov; 169(5):276-9. doi: . [PMID: 9830355]
  • S L Nielsen, F T Black. The effect of dicloxacillin and fusidic acid on the extracellular and intracellular killing of Staphylococcus aureus. The Journal of antimicrobial chemotherapy. 1998 Aug; 42(2):221-6. doi: 10.1093/jac/42.2.221. [PMID: 9738840]
  • A T Mailloux, B E Gidal, C A Sorkness. Potential interaction between warfarin and dicloxacillin. The Annals of pharmacotherapy. 1996 Dec; 30(12):1402-7. doi: 10.1177/106002809603001208. [PMID: 8968452]
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  • M R Krogsgaard, B A Hansen, T Slotsbjerg, P Jensen. Should probenecid be used to reduce the dicloxacillin dosage in orthopaedic infections? A study of the dicloxacillin-saving effect of probenecid. Pharmacology & toxicology. 1994 Mar; 74(3):181-4. doi: 10.1111/j.1600-0773.1994.tb01096.x. [PMID: 8008725]
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