thioxanthene (BioDeep_00000789926)
代谢物信息卡片
thioxanthene
化学式: C13H10S (198.050318)
中文名称: 阿奇霉素杂质B
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C2=CC=CC=C2SC3=CC=CC=C31
InChI: InChI=1S/C13H10S/c1-3-7-12-10(5-1)9-11-6-2-4-8-13(11)14-12/h1-8H,9H2
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- P A Blaker, M Arenas-Hernandez, M A Smith, E A Shobowale-Bakre, L Fairbanks, P M Irving, J D Sanderson, A M Marinaki. Mechanism of allopurinol induced TPMT inhibition.
Biochemical pharmacology.
2013 Aug; 86(4):539-47. doi:
10.1016/j.bcp.2013.06.002. [PMID: 23770457] - Seong Taeck Kim, Jae Woong Koh, Joon Mo Kim, Won Young Kim, Gwang Ju Choi. Methotrimeprazine-induced corneal deposits and cataract revealed by urine drug profiling test.
Journal of Korean medical science.
2010 Nov; 25(11):1688-91. doi:
10.3346/jkms.2010.25.11.1688. [PMID: 21060765] - Ahmed F Hawwa, Jeff S Millership, Paul S Collier, James C McElnay. Development and validation of an HPLC method for the rapid and simultaneous determination of 6-mercaptopurine and four of its metabolites in plasma and red blood cells.
Journal of pharmaceutical and biomedical analysis.
2009 Feb; 49(2):401-9. doi:
10.1016/j.jpba.2008.10.045. [PMID: 19095392] - Sukirti Kalra, Gopabandhu Jena, Kulbhushan Tikoo, Anup Kumar Mukhopadhyay. Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol.
BMC biochemistry.
2007 May; 8(?):8. doi:
10.1186/1471-2091-8-8. [PMID: 17511860] - Wang-Fun Fong, Chi-Keung Wan, Guo-Yuan Zhu, Apurba Chattopadhyay, Saibal Dey, Zhongzhen Zhao, Xiao-Ling Shen. Schisandrol A from Schisandra chinensis reverses P-glycoprotein-mediated multidrug resistance by affecting Pgp-substrate complexes.
Planta medica.
2007 Mar; 73(3):212-20. doi:
10.1055/s-2007-967120. [PMID: 17318783] - Nazli Maki, Saibal Dey. Biochemical and pharmacological properties of an allosteric modulator site of the human P-glycoprotein (ABCB1).
Biochemical pharmacology.
2006 Jul; 72(2):145-55. doi:
10.1016/j.bcp.2006.04.008. [PMID: 16729976] - Chun-Chi Wang, Shyh-Shin Chiou, Shou-Mei Wu. Determination of mercaptopurine and its four metabolites by large-volume sample stacking with polarity switching in capillary electrophoresis.
Electrophoresis.
2005 Jun; 26(13):2637-42. doi:
10.1002/elps.200500003. [PMID: 15934057] - Sjofn Gunnarsdottir, Adnan A Elfarra. Distinct tissue distribution of metabolites of the novel glutathione-activated thiopurine prodrugs cis-6-(2-acetylvinylthio)purine and trans-6-(2-acetylvinylthio)guanine and 6-thioguanine in the mouse.
Drug metabolism and disposition: the biological fate of chemicals.
2003 Jun; 31(6):718-26. doi:
10.1124/dmd.31.6.718. [PMID: 12756203] - Sjofn Gunnarsdottir, Marian Rucki, Lynette A Phillips, Karen M Young, Adnan A Elfarra. The glutathione-activated thiopurine prodrugs trans-6-(2-acetylvinylthio)guanine and cis-6-(2-acetylvinylthio)purine cause less in vivo toxicity than 6-thioguanine after single- and multiple-dose regimens.
Molecular cancer therapeutics.
2002 Nov; 1(13):1211-20. doi:
NULL. [PMID: 12479702] - Piyarat Govitrapong, Sujira Mukda, Wanpen Turakitwanakan, Hattaya Dumrongphol, Chittin Chindaduangratn, Yupin Sanvarinda. Platelet serotonin transporter in schizophrenic patients with and without neuroleptic treatment.
Neurochemistry international.
2002 Oct; 41(4):209-16. doi:
10.1016/s0197-0186(02)00024-4. [PMID: 12106771] - Jean Debord, Louis Merle, Jean-Claude Bollinger, Thierry Dantoine. Inhibition of butyrylcholinesterase by phenothiazine derivatives.
Journal of enzyme inhibition and medicinal chemistry.
2002 Jun; 17(3):197-202. doi:
10.1080/1475636021000003165. [PMID: 12443046] - R Schlösser, G Gründer, I Anghelescu, A Hillert, S Ewald-Gründer, C Hiemke, O Benkert. Long-term effects of the substituted benzamide derivative amisulpride on baseline and stimulated prolactin levels.
Neuropsychobiology.
2002; 46(1):33-40. doi:
10.1159/000063574. [PMID: 12207145] - F A Aly, S A al-Tamimi, A A Alwarthan. Flow-injection chemiluminometric determination of some thioxanthene derivatives in pharmaceutical formulations and biological fluids using the [Ru(dipy)3(2+)]-Ce(IV) system.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2001 Nov; 17(11):1257-61. doi:
10.2116/analsci.17.1257. [PMID: 11759505]