3-Deoxyglucosone (BioDeep_00000789541)
Main id: BioDeep_00000173893
代谢物信息卡片
D-3-Deoxyglucosone
化学式: C6H10O5 (162.052821)
中文名称: 3-葡萄糖醛酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(=O)C=O)[C@@H]([C@@H](CO)O)O
InChI: InChI=1S/C6H10O5/c7-2-4(9)1-5(10)6(11)3-8/h2,5-6,8,10-11H,1,3H2/t5-,6+/m0/s1
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:60777
- PubChem: 114839
- CAS: 624740-14-3
- CAS: 30382-30-0
- CAS: 4084-27-9
- KEGG: C22311
- RefMet: 3-Deoxyglucosone
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yang Yang, Hai-Ling Wang, Rui-Tong Cheng, Pei-Rong Zheng, Hui-Peng Sun, Zhi-Wen Liu, Heng Yuan, Xue-Yi Liu, Wen-Yun Gao, Heng Li. Determination of α-Dicarbonyl compounds in traditional Chinese herbal medicines.
Fitoterapia.
2024 Jun; 175(?):105928. doi:
10.1016/j.fitote.2024.105928. [PMID: 38548027] - Catrin Herpich, Bastian Kochlik, Daniela Weber, Christiane Ott, Tilman Grune, Kristina Norman, Jana Raupbach. Fasting Concentrations and Postprandial Response of 1,2-Dicarbonyl Compounds 3-Deoxyglucosone, Glyoxal, and Methylglyoxal Are Not Increased in Healthy Older Adults.
The journals of gerontology. Series A, Biological sciences and medical sciences.
2022 05; 77(5):934-940. doi:
10.1093/gerona/glab331. [PMID: 34726231] - Kim Maasen, Simone J P M Eussen, Jean L J M Scheijen, Carla J H van der Kallen, Pieter C Dagnelie, Antoon Opperhuizen, Coen D A Stehouwer, Marleen M J van Greevenbroek, Casper G Schalkwijk. Higher habitual intake of dietary dicarbonyls is associated with higher corresponding plasma dicarbonyl concentrations and skin autofluorescence: the Maastricht Study.
The American journal of clinical nutrition.
2022 01; 115(1):34-44. doi:
10.1093/ajcn/nqab329. [PMID: 34625788] - M Piazza, N M J Hanssen, F Persson, J L Scheijen, M P H van de Waarenburg, M M J van Greevenbroek, P Rossing, P Hovind, C D A Stehouwer, H-H Parving, C G Schalkwijk. Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub-study.
Diabetic medicine : a journal of the British Diabetic Association.
2021 09; 38(9):e14405. doi:
10.1111/dme.14405. [PMID: 32961617] - Shingo Yoshioka, Hiroko Odani, Tadaaki Furuhashi, Tsutomu Tanaka, Toyoaki Ogawa. Increase in the peripheral blood methylglyoxal levels in 10\% of hospitalized chronic schizophrenia patients.
Nagoya journal of medical science.
2021 Feb; 83(1):51-61. doi:
10.18999/nagjms.83.1.51. [PMID: 33727737] - Afreen Khanam, Saheem Ahmad, Arbab Husain, Shahnawaz Rehman, Alvina Farooqui, Mohd Aslam Yusuf. Glycation and Antioxidants: Hand in the Glove of Antiglycation and Natural Antioxidants.
Current protein & peptide science.
2020; 21(9):899-915. doi:
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BioMed research international.
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10.1155/2020/8406846. [PMID: 32908918] - Xin-Jie Wang, Hong-Xia Zhang, Heng Li, Ai-Hua Zhu, Wen-Yun Gao. Measurement of α-dicarbonyl compounds in human saliva by pre-column derivatization HPLC.
Clinical chemistry and laboratory medicine.
2019 Nov; 57(12):1915-1922. doi:
10.1515/cclm-2019-0350. [PMID: 31377732] - Xiudao Song, Guoqiang Liang, Min Shi, Liang Zhou, Fei Wang, Lurong Zhang, Fei Huang, Guorong Jiang. Acute exposure to 3‑deoxyglucosone at high glucose levels impairs insulin secretion from β‑cells by downregulating the sweet taste receptor signaling pathway.
Molecular medicine reports.
2019 Jun; 19(6):5015-5022. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2019 Feb; 1106-1107(?):19-25. doi:
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PloS one.
2019; 14(8):e0221058. doi:
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Archives of physiology and biochemistry.
2018 Dec; 124(5):430-435. doi:
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Biochemistry. Biokhimiia.
2018 Nov; 83(11):1358-1368. doi:
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Diabetes care.
2018 03; 41(3):570-576. doi:
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Molecular medicine reports.
2017 Sep; 16(3):2976-2984. doi:
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Diabetes care.
2017 Apr; 40(4):591-598. doi:
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International journal of molecular sciences.
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Food research international (Ottawa, Ont.).
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Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.
2017 Jan; 125(1):4-11. doi:
10.1055/s-0042-111684. [PMID: 27658000] - G Liang, X Song, H Xu, F Wang, L Zhang, L Zhou, G Jiang. 3-Deoxyglucosone Induced Acute Glucose Intolerance in Sprague-Dawley Rats: Involvement of Insulin Resistance and Impaired β-cell Function.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.
2016 Jul; 124(7):431-6. doi:
10.1055/s-0035-1565193. [PMID: 26824285] - Guoqiang Liang, Fei Wang, Xiudao Song, Lurong Zhang, Zhen Qian, Guorong Jiang. 3-Deoxyglucosone induces insulin resistance by impairing insulin signaling in HepG2 cells.
Molecular medicine reports.
2016 May; 13(5):4506-12. doi:
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Diabetes care.
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PloS one.
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Journal of agricultural and food chemistry.
2014 Mar; 62(11):2449-56. doi:
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Diabetes & metabolic syndrome.
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Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
2008 May; 28(3):277-82. doi:
10.1177/089686080802800315. [PMID: 18474921] - François Collard, Didier Vertommen, Juliette Fortpied, Gregg Duester, Emile Van Schaftingen. Identification of 3-deoxyglucosone dehydrogenase as aldehyde dehydrogenase 1A1 (retinaldehyde dehydrogenase 1).
Biochimie.
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Journal of biochemistry.
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