Hesperadin (BioDeep_00000788481)
代谢物信息卡片
化学式: C29H32N4O3S (516.2195002)
中文名称: Hesperadin
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCS(=O)(=O)NC1=CC2=C(C=C1)NC(=C2C(=NC3=CC=C(C=C3)CN4CCCCC4)C5=CC=CC=C5)O
InChI: InChI=1S/C29H32N4O3S/c1-2-37(35,36)32-24-15-16-26-25(19-24)27(29(34)31-26)28(22-9-5-3-6-10-22)30-23-13-11-21(12-14-23)20-33-17-7-4-8-18-33/h3,5-6,9-16,19,31-32,34H,2,4,7-8,17-18,20H2,1H3
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:70726
- PubChem: 135421442
- ChEMBL: CHEMBL514409
- CAS: 1265801-59-9
- CAS: 422513-13-1
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Yanmei Hu, Jiantao Zhang, Rami Musharrafieh, Raymond Hau, Chunlong Ma, Jun Wang. Chemical Genomics Approach Leads to the Identification of Hesperadin, an Aurora B Kinase Inhibitor, as a Broad-Spectrum Influenza Antiviral.
International journal of molecular sciences.
2017 Sep; 18(9):. doi:
10.3390/ijms18091929
. [PMID: 28885544] - M Namik Oztanir, Osman Ciftci, Aslı Cetin, M Arif Aladag. Hesperidin attenuates oxidative and neuronal damage caused by global cerebral ischemia/reperfusion in a C57BL/J6 mouse model.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology.
2014 Sep; 35(9):1393-9. doi:
10.1007/s10072-014-1725-5
. [PMID: 24676696] - Dmitri Demidov, Susann Hesse, Annegret Tewes, Twan Rutten, Jörg Fuchs, Raheleh Karimi Ashtiyani, Sandro Lein, Andreas Fischer, Gunter Reuter, Andreas Houben. Aurora1 phosphorylation activity on histone H3 and its cross-talk with other post-translational histone modifications in Arabidopsis.
The Plant journal : for cell and molecular biology.
2009 Jul; 59(2):221-30. doi:
10.1111/j.1365-313x.2009.03861.x
. [PMID: 19582900] - Daisuke Kurihara, Sachihiro Matsunaga, Susumu Uchiyama, Kiichi Fukui. Live cell imaging reveals plant aurora kinase has dual roles during mitosis.
Plant & cell physiology.
2008 Aug; 49(8):1256-61. doi:
10.1093/pcp/pcn098
. [PMID: 18593743] - Daisuke Kurihara, Sachihiro Matsunaga, Akira Kawabe, Satoru Fujimoto, Masanori Noda, Susumu Uchiyama, Kiichi Fukui. Aurora kinase is required for chromosome segregation in tobacco BY-2 cells.
The Plant journal : for cell and molecular biology.
2006 Nov; 48(4):572-80. doi:
10.1111/j.1365-313x.2006.02893.x
. [PMID: 17087760] - Michinori Kubo, Hideaki Matsuda, Norimichi Tomohiro, Shouichi Harima. [History and therapeutic evaluation of Citrus hassaku HORT. Tanaka].
Yakushigaku zasshi.
2004; 39(2):363-4. doi:
. [PMID: 16025659]