Heptadecafluoro-N-methyloctanesulphonamide (BioDeep_00000788244)
代谢物信息卡片
1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-N-methyloctane-1-sulfonamide
化学式: C9H4F17NO2S (512.9691)
中文名称: N-甲基-全氟辛烷-1-磺酰胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CNS(=O)(=O)C(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F
InChI: InChI=1S/C9H4F17NO2S/c1-27-30(28,29)9(25,26)7(20,21)5(16,17)3(12,13)2(10,11)4(14,15)6(18,19)8(22,23)24/h27H,1H3
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Weilan Zhang, Yanna Liang. Interactions between Lemna minor (common duckweed) and PFAS intermediates: Perfluorooctanesulfonamide (PFOSA) and 6:2 fluorotelomer sulfonate (6:2 FTSA).
Chemosphere.
2021 Aug; 276(?):130165. doi:
10.1016/j.chemosphere.2021.130165. [PMID: 33714153] - Subham Dasgupta, Aalekhya Reddam, Zekun Liu, Jinyong Liu, David C Volz. High-content screening in zebrafish identifies perfluorooctanesulfonamide as a potent developmental toxicant.
Environmental pollution (Barking, Essex : 1987).
2020 Jan; 256(?):113550. doi:
10.1016/j.envpol.2019.113550. [PMID: 31706782] - Eriko Yamazaki, Sachi Taniyasu, Kosuke Noborio, Heesoo Eun, Pooja Thaker, Nirmal J I Kumar, Xinhong Wang, Nobuyoshi Yamashita. Accumulation of perfluoroalkyl substances in lysimeter-grown rice in Japan using tap water and simulated contaminated water.
Chemosphere.
2019 Sep; 231(?):502-509. doi:
10.1016/j.chemosphere.2019.05.022. [PMID: 31151010] - Shuyan Zhao, Tiankun Liang, Tao Zhou, Dongqi Li, Bohui Wang, Jingjing Zhan, Lifen Liu. Biotransformation and responses of antioxidant enzymes in hydroponically cultured soybean and pumpkin exposed to perfluorooctane sulfonamide (FOSA).
Ecotoxicology and environmental safety.
2018 10; 161(?):669-675. doi:
10.1016/j.ecoenv.2018.06.048. [PMID: 29935431] - Shuyan Zhao, Tao Zhou, Lingyan Zhu, Bohui Wang, Ze Li, Liping Yang, Lifen Liu. Uptake, translocation and biotransformation of N-ethyl perfluorooctanesulfonamide (N-EtFOSA) by hydroponically grown plants.
Environmental pollution (Barking, Essex : 1987).
2018 Apr; 235(?):404-410. doi:
10.1016/j.envpol.2017.12.053. [PMID: 29306808] - Kirsten J Lum, Rajeshwari Sundaram, Dana B Barr, Thomas A Louis, Germaine M Buck Louis. Perfluoroalkyl Chemicals, Menstrual Cycle Length, and Fecundity: Findings from a Prospective Pregnancy Study.
Epidemiology (Cambridge, Mass.).
2017 01; 28(1):90-98. doi:
10.1097/ede.0000000000000552. [PMID: 27541842] - E Bizkarguenaga, I Zabaleta, L Mijangos, A Iparraguirre, L A Fernández, A Prieto, O Zuloaga. Uptake of perfluorooctanoic acid, perfluorooctane sulfonate and perfluorooctane sulfonamide by carrot and lettuce from compost amended soil.
The Science of the total environment.
2016 Nov; 571(?):444-51. doi:
10.1016/j.scitotenv.2016.07.010. [PMID: 27450950] - Kristina W Whitworth, Line S Haug, Azemira Sabaredzovic, Merete Eggesbo, Matthew P Longnecker. Brief Report: Plasma Concentrations of Perfluorooctane Sulfonamide and Time-to-pregnancy Among Primiparous Women.
Epidemiology (Cambridge, Mass.).
2016 09; 27(5):712-5. doi:
10.1097/ede.0000000000000524. [PMID: 27276029] - Meng Chen, Liwen Qiang, Xiaoyu Pan, Shuhong Fang, Yuwei Han, Lingyan Zhu. In Vivo and in Vitro Isomer-Specific Biotransformation of Perfluorooctane Sulfonamide in Common Carp (Cyprinus carpio).
Environmental science & technology.
2015 Dec; 49(23):13817-24. doi:
10.1021/acs.est.5b00488. [PMID: 26053759] - Shaogang Chu, Robert J Letcher. In vitro metabolic formation of perfluoroalkyl sulfonamides from copolymer surfactants of pre- and post-2002 scotchgard fabric protector products.
Environmental science & technology.
2014 Jun; 48(11):6184-91. doi:
10.1021/es500169x. [PMID: 24784168] - Itsaso Zabaleta, Ekhiñe Bizkarguenaga, Arantza Iparragirre, Patricia Navarro, Ailette Prieto, Luis Ángel Fernández, Olatz Zuloaga. Focused ultrasound solid-liquid extraction for the determination of perfluorinated compounds in fish, vegetables and amended soil.
Journal of chromatography. A.
2014 Feb; 1331(?):27-37. doi:
10.1016/j.chroma.2014.01.025. [PMID: 24495790] - Trine Reistad, Frode Fonnum, Espen Mariussen. Perfluoroalkylated compounds induce cell death and formation of reactive oxygen species in cultured cerebellar granule cells.
Toxicology letters.
2013 Mar; 218(1):56-60. doi:
10.1016/j.toxlet.2013.01.006. [PMID: 23340305] - Eliza H K Leat, Sophie Bourgeon, Jude I Eze, Derek C G Muir, Mary Williamson, Jan O Bustnes, Robert W Furness, Katrine Borgå. Perfluoroalkyl substances in eggs and plasma of an avian top predator, great skua (Stercorarius skua), in the North Atlantic.
Environmental toxicology and chemistry.
2013 Mar; 32(3):569-76. doi:
10.1002/etc.2101. [PMID: 23258709] - Ane Marit Wågbø, Maria V Cangialosi, Nicola Cicero, Robert J Letcher, Augustine Arukwe. Perfluorooctane sulfonamide-mediated modulation of hepatocellular lipid homeostasis and oxidative stress responses in Atlantic salmon hepatocytes.
Chemical research in toxicology.
2012 Jun; 25(6):1253-64. doi:
10.1021/tx300110u. [PMID: 22594583] - Jesus Olivero-Verbel, Lin Tao, Boris Johnson-Restrepo, Jorge Guette-Fernández, Rosa Baldiris-Avila, Indira O'byrne-Hoyos, Kurunthachalam Kannan. Perfluorooctanesulfonate and related fluorochemicals in biological samples from the north coast of Colombia.
Environmental pollution (Barking, Essex : 1987).
2006 Jul; 142(2):367-72. doi:
10.1016/j.envpol.2005.09.022. [PMID: 16303219] - Anna Kärrman, Bert van Bavel, Ulf Järnberg, Lennart Hardell, Gunilla Lindström. Development of a solid-phase extraction-HPLC/single quadrupole MS method for quantification of perfluorochemicals in whole blood.
Analytical chemistry.
2005 Feb; 77(3):864-70. doi:
10.1021/ac049023c. [PMID: 15679355] - Koichi Inoue, Fumio Okada, Rie Ito, Migaku Kawaguchi, Noriya Okanouchi, Hiroyuki Nakazawa. Determination of perfluorooctane sulfonate, perfluorooctanoate and perfluorooctane sulfonylamide in human plasma by column-switching liquid chromatography-electrospray mass spectrometry coupled with solid-phase extraction.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2004 Oct; 810(1):49-56. doi:
10.1016/j.jchromb.2004.07.014. [PMID: 15358307] - Kurunthachalam Kannan, Simonetta Corsolini, Jerzy Falandysz, Gilberto Fillmann, Kurunthachalam Senthil Kumar, Bommanna G Loganathan, Mustafa Ali Mohd, Jesus Olivero, Nathalie Van Wouwe, Jae Ho Yang, Kenneth M Aldoust. Perfluorooctanesulfonate and related fluorochemicals in human blood from several countries.
Environmental science & technology.
2004 Sep; 38(17):4489-95. doi:
10.1021/es0493446. [PMID: 15461154] - Jonathan M Shipley, Christopher H Hurst, Sue S Tanaka, Fred L DeRoos, John L Butenhoff, Andrew M Seacat, David J Waxman. trans-activation of PPARalpha and induction of PPARalpha target genes by perfluorooctane-based chemicals.
Toxicological sciences : an official journal of the Society of Toxicology.
2004 Jul; 80(1):151-60. doi:
10.1093/toxsci/kfh130. [PMID: 15071170] - Wenyue Hu, Paul D Jones, Brad L Upham, James E Trosko, Christopher Lau, John P Giesy. Inhibition of gap junctional intercellular communication by perfluorinated compounds in rat liver and dolphin kidney epithelial cell lines in vitro and Sprague-Dawley rats in vivo.
Toxicological sciences : an official journal of the Society of Toxicology.
2002 Aug; 68(2):429-36. doi:
10.1093/toxsci/68.2.429. [PMID: 12151638] - Kurunthachalam Kannan, John Newsted, Richard S Halbrook, John P Giesy. Perfluorooctanesulfonate and related fluorinated hydrocarbons in mink and river otters from the United States.
Environmental science & technology.
2002 Jun; 36(12):2566-71. doi:
10.1021/es0205028. [PMID: 12099451] - R G Schnellmann, R O Manning. Perfluorooctane sulfonamide: a structurally novel uncoupler of oxidative phosphorylation.
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