7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline (BioDeep_00000785693)

   


代谢物信息卡片


Isoquinoline, 7,9-dichloro-1,2,3,4-tetrahydro-

化学式: C9H9Cl2N (201.0112014)
中文名称: 7,8-二氯-1,2,3,4-四氢异喹啉
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CNCC2=C1C=CC(=C2Cl)Cl
InChI: InChI=1S/C9H9Cl2N/c10-8-2-1-6-3-4-12-5-7(6)9(8)11/h1-2,12H,3-5H2

描述信息

D004791 - Enzyme Inhibitors > D008996 - Monoamine Oxidase Inhibitors

同义名列表

2 个代谢物同义名

Isoquinoline, 7,9-dichloro-1,2,3,4-tetrahydro-; 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • A Giovambattista, A N Chisari, R C Gaillard, E Spinedi. Modulatory role of the epinergic system in the neuroendocrine-immune system function. Neuroimmunomodulation. 2000; 8(2):98-106. doi: 10.1159/000026459. [PMID: 10965235]
  • N Matussek, L Deuringer, I Sardas-Trevorrow. Effect of serum on adrenal PNMT activity. Journal of neural transmission. General section. 1992; 89(1-2):135-8. doi: 10.1007/bf01245360. [PMID: 1418865]
  • E Spinedi, C A Johnston, A Chisari, A Negro-Vilar. Role of central epinephrine on the regulation of corticotropin-releasing factor and adrenocorticotropin secretion. Endocrinology. 1988 May; 122(5):1977-83. doi: 10.1210/endo-122-5-1977. [PMID: 2834181]
  • S G Cella, V Locatelli, V De Gennaro, G P Bondiolotti, C Pintor, S Loche, M Provezza, E E Müller. Epinephrine mediates the growth hormone-releasing effect of galanin in infant rats. Endocrinology. 1988 Mar; 122(3):855-9. doi: 10.1210/endo-122-3-855. [PMID: 2449342]
  • L C Terry. Regulation of thyrotropin secretion by the central epinephrine system. Studies in the chronically cannulated rat. Neuroendocrinology. 1986; 42(2):102-8. doi: 10.1159/000124258. [PMID: 3005895]
  • E Castro-e-Silva, K O Nonaka, J Antunes-Rodrigues. Effect of a selective inhibitor of epinephrine synthesis, SK&F 64 139, on prolactin secretion in the rat. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 1986; 19(3):389-94. doi: NULL. [PMID: 3594004]
  • D DiPette, B Waeber, L Volicer, P Chao, I Gavras, H Gavras, H Brunner. Salt-induced hypertension in chronic renal failure: evidence for a neurogenic mechanism. Life sciences. 1983 Feb; 32(7):733-40. doi: 10.1016/0024-3205(83)90306-5. [PMID: 6827908]
  • C Rosendorff, J R Melamed, M L Hurwitz, A Coull, A Jarvis. Inhibition of adrenaline-forming enzyme in the brain prevents one-kidney, one-clip hypertension and deoxycorticosterone acetate-salt hypertension in the rabbit. Clinical science (London, England : 1979). 1982 Dec; 63(6):573-6. doi: 10.1042/cs0630573. [PMID: 7128025]
  • B Waeber, H Gavras, I Gavras, P Chao, O Kohlman, M R Bresnahan, H R Brunner, D Vaughan. Evidence for a sodium-induced activation of central neurogenic mechanisms in one-kidney, one-clip renal hypertensive rats. The Journal of pharmacology and experimental therapeutics. 1982 Nov; 223(2):510-5. doi: . [PMID: 6752375]
  • S P Kalra, W R Crowley. Epinephrine synthesis inhibitors block naloxone-induced LH release. Endocrinology. 1982 Oct; 111(4):1403-5. doi: 10.1210/endo-111-4-1403. [PMID: 7117202]
  • J Black, B Waeber, M R Bresnahan, I Gavras, H Gavras. Blood pressure response to central and/or peripheral inhibition of phenylethanolamine N-methyltransferase in normotensive and hypertensive rats. Circulation research. 1981 Aug; 49(2):518-24. doi: 10.1161/01.res.49.2.518. [PMID: 7249286]
  • J W Dubb, R M Stote, F Alexander, A P Intoccia, M Geczy, R G Pendleton. Studies with a PNMT inhibitor. Clinical pharmacology and therapeutics. 1979 Jun; 25(6):837-43. doi: 10.1002/cpt1979256837. [PMID: 445951]