Simethicone (BioDeep_00000784021)
代谢物信息卡片
Simethicone
化学式: C6H18O4Si3 (238.0512868)
中文名称: 二甲硅油
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CO[Si](C)(C)O[Si](C)(C)C.O=[Si]=O
InChI: 1-3-2/h1-6H3
描述信息
D013501 - Surface-Active Agents > D000934 - Antifoaming Agents
D003879 - Dermatologic Agents > D004643 - Emollients
D001697 - Biomedical and Dental Materials
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Karen Paola Camarillo Cárdenas, Jessica García González, Federico Alberto Argüelles Tello, Jorge Arturo Ocampo Ramírez, José Belisario Moreno Hernández, Murali Mohan Pendela. Relative bioavailability and pharmacokinetic comparison of a fixed-dose combination tablet of mosapride, pancreatin, and simethicone relative to single-component mosapride tablets in healthy Mexican subjects.
Fundamental & clinical pharmacology.
2022 Apr; 36(2):427-435. doi:
10.1111/fcp.12739. [PMID: 34837418] - Franchek Drobnic, Sergi Fonts, Iker García-Alday, Giovanna Petrangolini, Antonella Riva, Elisabetta Frattini, Pietro Allegrini, Stefano Togni, Jacopo Vitale. Efficacy of artichoke and ginger extracts with simethicone to treat gastrointestinal symptoms in endurance athletes: a pilot study.
Minerva gastroenterology.
2022 Mar; 68(1):77-84. doi:
10.23736/s2724-5985.20.02664-1. [PMID: 31994374] - Sauzanne G Khalilieh, Ka Lai Yee, Rosa I Sanchez, Li Fan, Kate Vaynshteyn, Kathleen Deschamps, Maureen Martell, Heather R Jordan, Marian Iwamoto. A Study to Evaluate Doravirine Pharmacokinetics When Coadministered With Acid-Reducing Agents.
Journal of clinical pharmacology.
2019 08; 59(8):1093-1098. doi:
10.1002/jcph.1399. [PMID: 30817001] - Shenghong Zhang, Danping Zheng, Jinping Wang, Jianwei Wu, Pingguang Lei, Qi Luo, Liping Wang, Beiping Zhang, Hong Wang, Yi Cui, Minhu Chen. Simethicone improves bowel cleansing with low-volume polyethylene glycol: a multicenter randomized trial.
Endoscopy.
2018 04; 50(4):412-422. doi:
10.1055/s-0043-121337. [PMID: 29132175] - Kassy Gomes da Silva, Carla de Andrade, Cristina Santos Sotomaior. Influence of simethicone and fasting on the quality of abdominal ultrasonography in New Zealand White rabbits.
Acta veterinaria Scandinavica.
2017 Jul; 59(1):48. doi:
10.1186/s13028-017-0316-x. [PMID: 28716083] - Kenji Wakabayashi, Hiroko Kodama, Eishin Ogawa, Yasuhiro Sato, Kahoko Motoyama, Mitsuyoshi Suzuki. Serum biotin in Japanese children: Enzyme-linked immunosorbent assay measurement.
Pediatrics international : official journal of the Japan Pediatric Society.
2016 Sep; 58(9):872-6. doi:
10.1111/ped.12968. [PMID: 26933789] - Lionel Bueno, Catherine Beaufrand, Vassilia Theodorou, Marie-Christine Andro-Delestrain. Influence of simethicone and alverine on stress-induced alterations of colonic permeability and sensitivity in rats: beneficial effect of their association.
The Journal of pharmacy and pharmacology.
2013 Apr; 65(4):567-73. doi:
10.1111/jphp.12021. [PMID: 23488786] - Katharina Breme, Nadine Guillamon, Xavier Fernandez, Pascal Tournayre, Hugues Brevard, Daniel Joulain, Jean Louis Berdagué, Uwe J Meierhenrich. First identification of O,S-diethyl Thiocarbonate in Indian Cress absolute and odor evaluation of its synthesized homologues by GC-sniffing.
Journal of agricultural and food chemistry.
2009 Mar; 57(6):2503-7. doi:
10.1021/jf8035319. [PMID: 19292470] - Andrew Hoggarth, Mike Waring, James Alexander, Amanada Greenwood, Theresa Callaghan. A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants.
Ostomy/wound management.
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Veterinary parasitology.
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Journal of controlled release : official journal of the Controlled Release Society.
2000 Jan; 63(1-2):7-17. doi:
10.1016/s0168-3659(99)00169-8. [PMID: 10640576] - N Presle, F Lapicque, P Gillet, M A Herrmann, B Bannwarth, P Netter. Effect of dimethicone (polysilane gel) on the stereoselective pharmacokinetics of ketoprofen.
European journal of clinical pharmacology.
1998 Jun; 54(4):351-4. doi:
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American journal of therapeutics.
1998 Mar; 5(2):67-72. doi:
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Clinical pediatrics.
1995 Feb; 34(2):73-8. doi:
10.1177/000992289503400202. [PMID: 7729110] - W Kark, H Krebs-Richter, J Hotz. [Improving the effect of orthograde colonic lavage with golytely solution by adding dimethicone].
Zeitschrift fur Gastroenterologie.
1995 Jan; 33(1):20-3. doi:
NULL. [PMID: 7886982] - J M Herrerías Gutiérrez, J García Montes. The effect of clebopride-simethicone combination therapy on echographic visualization of retrogastric organs.
Clinical therapeutics.
1994 May; 16(3):483-9. doi:
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Dermatology (Basel, Switzerland).
1994; 189(4):373-7. doi:
10.1159/000246882. [PMID: 7873823] - X Copie, J L Pinquier, M Letrait, M H Paltiat, J Y Pello, E Rey, G Chanteclair, D de Lauture, G Olive, G Strauch. [Effect of dimethicone on pharmacokinetics and pharmacodynamics of ethyl biscoumacetate].
Therapie.
1993 Mar; 48(2):119-23. doi:
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Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
1992 Dec; 6(4):247-51. doi:
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Likars'ka sprava.
1992 Feb; ?(2):90-3. doi:
NULL. [PMID: 1441347] - J Foldes, R Balena, A Ho, A M Parfitt, M Kleerekoper. Hypophosphatemic rickets with hypocalciuria following long-term treatment with aluminum-containing antacid.
Bone.
1991; 12(2):67-71. doi:
10.1016/8756-3282(91)90002-z. [PMID: 2064842] - N Barzaghi, F Crema, G Mescoli, E Perucca. Effects on cimetidine bioavailability of metoclopramide and antacids given two hours apart.
European journal of clinical pharmacology.
1989; 37(4):409-10. doi:
10.1007/bf00558511. [PMID: 2598975] - W A Shaver, P Storms, W L Peterson. Improvement of oral colonic lavage with supplemental simethicone.
Digestive diseases and sciences.
1988 Feb; 33(2):185-8. doi:
10.1007/bf01535731. [PMID: 3338367] - G M Shah, R L Winer, R E Cutler, A I Arieff, W G Goodman, J W Lacher, P Y Schoenfeld, J W Coburn, A M Horowitz. Effects of a magnesium-free dialysate on magnesium metabolism during continuous ambulatory peritoneal dialysis.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
1987 Oct; 10(4):268-75. doi:
10.1016/s0272-6386(87)80021-5. [PMID: 3661548] - W Heldwein, T Sommerlatte, J Hasford, P Lehnert, G Littig, S Müller-Lissner. Evaluation of the usefulness of dimethicone and/or senna extract in improving the visualization of abdominal organs.
Journal of clinical ultrasound : JCU.
1987 Sep; 15(7):455-8. doi:
10.1002/jcu.1870150705. [PMID: 3134446] - M A O'Neil-Cutting, W H Crosby. The effect of antacids on the absorption of simultaneously ingested iron.
JAMA.
1986 Mar; 255(11):1468-70. doi:
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Methods and findings in experimental and clinical pharmacology.
1985 Jul; 7(7):393-8. doi:
NULL. [PMID: 3903382] - C H Lifschitz, C S Irving, E O Smith. Effect of a simethicone-containing tablet on colonic gas elimination in breath.
Digestive diseases and sciences.
1985 May; 30(5):426-30. doi:
10.1007/bf01318174. [PMID: 3921328] - M M Van Ness, E L Cattau. Flatulence: pathophysiology and treatment.
American family physician.
1985 Apr; 31(4):198-208. doi:
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European journal of clinical pharmacology.
1985; 29(2):251-3. doi:
10.1007/bf00547432. [PMID: 4076324] - N Heyder, H Lutz, L Horbach. [Premedication for sonography. Enzyme-paractol in comparison with a placebo].
Fortschritte der Medizin.
1984 Sep; 102(34):850-2. doi:
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Anesthesiology.
1983 Aug; 59(2):86-90. doi:
10.1097/00000542-198308000-00003. [PMID: 6869899] - G W Mihaly, A T Marino, L K Webster, D B Jones, W J Louis, R A Smallwood. High dose of antacid (Mylanta II) reduces bioavailability of ranitidine.
British medical journal (Clinical research ed.).
1982 Oct; 285(6347):998-9. doi:
10.1136/bmj.285.6347.998. [PMID: 6289961] - S S Weber, A D Bankhurst, E Mroszczak, T L Ding. Effect of Mylanta on naproxen bioavailability.
Therapeutic drug monitoring.
1981; 3(1):75-83. doi:
NULL. [PMID: 7233492] - G Trieb. [Use of Paractol tablets for preparation of biliary- and kidney x-ray diagnosis].
Fortschritte der Medizin.
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