dimethylmercury (BioDeep_00000783848)
Main id: BioDeep_00000007386
代谢物信息卡片
dimethylmercury
化学式: C2H6Hg (232.0176)
中文名称: 二甲基汞
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C[Hg]C
InChI: InChI=1S/2CH3.Hg/h2*1H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Sebastian Granitzer, Isabella Ellinger, Rumsha Khan, Katharina Gelles, Raimund Widhalm, Markus Hengstschläger, Harald Zeisler, Gernot Desoye, Lenka Tupova, Martina Ceckova, Hans Salzer, Claudia Gundacker. In vitro function and in situ localization of Multidrug Resistance-associated Protein (MRP)1 (ABCC1) suggest a protective role against methyl mercury-induced oxidative stress in the human placenta.
Archives of toxicology.
2020 11; 94(11):3799-3817. doi:
10.1007/s00204-020-02900-5. [PMID: 32915249] - Woosuk Kim, Dae Young Yoo, Hyo Young Jung, Jong Whi Kim, Kyu Ri Hahn, Hyun Jung Kwon, Miyoung Yoo, Sanghee Lee, Sung Min Nam, Yeo Sung Yoon, Dae Won Kim, In Koo Hwang. Leaf extracts from Dendropanax morbifera Léveille mitigate mercury-induced reduction of spatial memory, as well as cell proliferation, and neuroblast differentiation in rat dentate gyrus.
BMC complementary and alternative medicine.
2019 May; 19(1):94. doi:
10.1186/s12906-019-2508-6. [PMID: 31046739] - Mark Xavier Bailon, Anneschel Sheehan David, Yeongeon Park, Eunhee Kim, Yongseok Hong. Total mercury, methyl mercury, and heavy metal concentrations in Hyeongsan River and its tributaries in Pohang city, South Korea.
Environmental monitoring and assessment.
2018 Apr; 190(5):274. doi:
10.1007/s10661-018-6624-4. [PMID: 29644448] - Han Wang, Beibei Chen, Man He, Xiaoxiao Yu, Bin Hu. Selenocystine against methyl mercury cytotoxicity in HepG2 cells.
Scientific reports.
2017 03; 7(1):147. doi:
10.1038/s41598-017-00231-7. [PMID: 28273949] - Natta Kachenpukdee, Charles R Santerre, Mario G Ferruzzi, Ratchadaporn Oonsivilai. Modified Dietary Fiber from Cassava Pulp and Assessment of Mercury Bioaccessibility and Intestinal Uptake Using an In Vitro Digestion/Caco-2 Model System.
Journal of food science.
2016 Jul; 81(7):T1854-63. doi:
10.1111/1750-3841.13336. [PMID: 27220052] - G P Cobb, A W Moore, K T Rummel, S T McMurry. Dimercaptopropane Sulfonate Chelation Affects In Vivo Hg and MeHg Distribution in Tissues and Urine of Prairie Voles (Microtus ochrogaster).
Bulletin of environmental contamination and toxicology.
2015 Dec; 95(6):707-13. doi:
10.1007/s00128-015-1651-0. [PMID: 26412077] - Dhanoop Manikoth Ayyathan, Rajasekaran Chandrasekaran, Kalaivani Thiagarajan. Neuroprotective effect of Tagara, an Ayurvedic drug against methyl mercury induced oxidative stress using rat brain mitochondrial fractions.
BMC complementary and alternative medicine.
2015 Aug; 15(?):268. doi:
10.1186/s12906-015-0793-2. [PMID: 26264039] - Benjamin D Barst, Kristin Bridges, Malgorzata Korbas, Aaron P Roberts, Kray Van Kirk, Kevin McNeel, Paul E Drevnick. The role of melano-macrophage aggregates in the storage of mercury and other metals: an example from yelloweye rockfish (Sebastes ruberrimus).
Environmental toxicology and chemistry.
2015 Aug; 34(8):1918-25. doi:
10.1002/etc.3009. [PMID: 26177920] - Xin-mei Wang, Su Zhang, Mei-bo Wang, Jing Xia, Li-min Li, Ke Wang, Shen Ji. [In vitro safety evaluation study of Angong Niuhuang Wan].
Guang pu xue yu guang pu fen xi = Guang pu.
2015 Jan; 35(1):238-41. doi:
". [PMID: 25993856] - Nobuo Ishihara. [History of ignorance of methylmercury toxicity and intoxication in Japan in relation to Minamata disease].
Nihon eiseigaku zasshi. Japanese journal of hygiene.
2014; 69(1):75-9. doi:
10.1265/jjh.69.75. [PMID: 24476597] - Wei Liu, Zhaofa Xu, Yu Deng, Bin Xu, Yangang Wei, Tianyao Yang. Protective effects of memantine against methylmercury-induced glutamate dyshomeostasis and oxidative stress in rat cerebral cortex.
Neurotoxicity research.
2013 Oct; 24(3):320-37. doi:
10.1007/s12640-013-9386-3. [PMID: 23504438] - Joshi Deepmala, Mittal Deepak, Sadhana Srivastav, Shukla Sangeeta, Srivastav Ajai Kumar, Srivastav Sunil Kumar. Protective effect of combined therapy with dithiothreitol, zinc and selenium protects acute mercury induced oxidative injury in rats.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).
2013 Jul; 27(3):249-56. doi:
10.1016/j.jtemb.2012.12.003. [PMID: 23428462] - Zhifu Liu, Zhenli Zhu, Hongtao Zheng, Shenghong Hu. Plasma jet desorption atomization-atomic fluorescence spectrometry and its application to mercury speciation by coupling with thin layer chromatography.
Analytical chemistry.
2012 Dec; 84(23):10170-4. doi:
10.1021/ac3028504. [PMID: 23153091] - Ellen E Yard, Jane Horton, Joshua G Schier, Kathleen Caldwell, Carlos Sanchez, Lauren Lewis, Carmen Gastaňaga. Mercury exposure among artisanal gold miners in Madre de Dios, Peru: a cross-sectional study.
Journal of medical toxicology : official journal of the American College of Medical Toxicology.
2012 Dec; 8(4):441-8. doi:
10.1007/s13181-012-0252-0. [PMID: 22926732] - Monika Ursinyova, Iveta Uhnakova, Rastislav Serbin, Vlasta Masanova, Zuzana Husekova, Ladislava Wsolova. The relation between human exposure to mercury and thyroid hormone status.
Biological trace element research.
2012 Sep; 148(3):281-91. doi:
10.1007/s12011-012-9382-0. [PMID: 22426797] - Stig Valdersnes, Amund Maage, Daniel Fliegel, Kåre Julshamn. A method for the routine determination of methylmercury in marine tissue by GC isotope dilution-ICP-MS.
Journal of AOAC International.
2012 Jul; 95(4):1189-94. doi:
10.5740/jaoacint.11-133. [PMID: 22970590] - Fang Peng, Hong Yang, Qin Wu, Jie Liu, Jingzhen Shi. [Studies on subacute toxicity of Wansheng Huafeng Dan in rats].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2012 Apr; 37(7):1017-22. doi:
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ACS chemical biology.
2012 Feb; 7(2):411-20. doi:
10.1021/cb200287c. [PMID: 22026432] - Ole Jakob Nøstbakken, Samuel A M Martin, Phillip Cash, Bente E Torstensen, Heidi Amlund, Pål A Olsvik. Dietary methylmercury alters the proteome in Atlantic salmon (Salmo salar) kidney.
Aquatic toxicology (Amsterdam, Netherlands).
2012 Feb; 108(?):70-7. doi:
10.1016/j.aquatox.2011.08.017. [PMID: 22265609] - Sandip Chattopadhyay, Ryan L Fimmen, Brian J Yates, Vivek Lal, Paul Randall. Phytoremediation of mercury- and methyl mercury-contaminated sediments by water hyacinth (Eichhornia crassipes).
International journal of phytoremediation.
2012 Feb; 14(2):142-61. doi:
10.1080/15226514.2010.525557. [PMID: 22567701] - Deepmala Joshi, Deepak Kumar Mittal, Sangeeta Shukla, Ajai Kumar Srivastav. Therapeutic potential of N-acetyl cysteine with antioxidants (Zn and Se) supplementation against dimethylmercury toxicity in male albino rats.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2012 Jan; 64(1-2):103-8. doi:
10.1016/j.etp.2010.07.001. [PMID: 20688495] - Marcos Lemes, Feiyue Wang, Gary A Stern, Sonja K Ostertag, Hing Man Chan. Methylmercury and selenium speciation in different tissues of beluga whales (Delphinapterus leucas) from the western Canadian Arctic.
Environmental toxicology and chemistry.
2011 Dec; 30(12):2732-8. doi:
10.1002/etc.684. [PMID: 21953916] - Deepmala Joshi, Deepak Mittal, Sadhana Shrivastav, Sangeeta Shukla, Ajai Kumar Srivastav. Combined effect of N-acetyl cysteine, zinc, and selenium against chronic dimethylmercury-induced oxidative stress: a biochemical and histopathological approach.
Archives of environmental contamination and toxicology.
2011 Nov; 61(4):558-67. doi:
10.1007/s00244-011-9656-0. [PMID: 21424224] - Luis Carrasco, Carlos Barata, Emili García-Berthou, Aurelio Tobias, Josep M Bayona, Sergi Díez. Patterns of mercury and methylmercury bioaccumulation in fish species downstream of a long-term mercury-contaminated site in the lower Ebro River (NE Spain).
Chemosphere.
2011 Sep; 84(11):1642-9. doi:
10.1016/j.chemosphere.2011.05.022. [PMID: 21663932] - Hsin-Yun Chang, Tung-Ming Hsiung, Yu-Fen Huang, Chih-Ching Huang. Using rhodamine 6G-modified gold nanoparticles to detect organic mercury species in highly saline solutions.
Environmental science & technology.
2011 Feb; 45(4):1534-9. doi:
10.1021/es103369d. [PMID: 21268634] - Deepmala Joshi, Deepak Kumar Mittal, Sadhana Shrivastava, Sangeeta Shukla. Protective role of thiol chelators against dimethylmercury induced toxicity in male rats.
Bulletin of environmental contamination and toxicology.
2010 May; 84(5):613-7. doi:
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Human & experimental toxicology.
2001 Apr; 20(4):185-8. doi:
10.1191/096032701678766813. [PMID: 11393270] - D W Nierenberg, R E Nordgren, M B Chang, R W Siegler, M B Blayney, F Hochberg, T Y Toribara, E Cernichiari, T Clarkson. Delayed cerebellar disease and death after accidental exposure to dimethylmercury.
The New England journal of medicine.
1998 Jun; 338(23):1672-6. doi:
10.1056/nejm199806043382305. [PMID: 9614258] - P N Kourounakis, E Rekka. Effect of spironolactone on dimethyl mercury toxicity. A possible molecular mechanism.
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