N,N-Dimethylthiourea (BioDeep_00000783042)
代谢物信息卡片
Thiourea, N,N-dimethyl-
化学式: C3H8N2S (104.0408168)
中文名称: N,N-二甲基硫脲
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN(C)C(=S)N
InChI: InChI=1S/C3H8N2S/c1-5(2)3(4)6/h1-2H3,(H2,4,6)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yu-ping Jiang, Fei Cheng, Yan-hong Zhou, Xiao-jian Xia, Wei-hua Mao, Kai Shi, Zhi-xiang Chen, Jing-quan Yu. Hydrogen peroxide functions as a secondary messenger for brassinosteroids-induced CO2 assimilation and carbohydrate metabolism in Cucumis sativus.
Journal of Zhejiang University. Science. B.
2012 Oct; 13(10):811-23. doi:
10.1631/jzus.b1200130. [PMID: 23024048] - Isabelle Six, Julien Maizel, Fellype C Barreto, Ashraf Y Rangrez, Sébastien Dupont, Michel Slama, Christophe Tribouilloy, Gabriel Choukroun, Jean Claude Mazière, Stefanie Bode-Boeger, Jan T Kielstein, Tilman B Drüeke, Ziad A Massy. Effects of phosphate on vascular function under normal conditions and influence of the uraemic state.
Cardiovascular research.
2012 Oct; 96(1):130-9. doi:
10.1093/cvr/cvs240. [PMID: 22822101] - O Cil, M Ertunc, R Onur. The diuretic effect of urea analog dimethylthiourea in female Wistar rats.
Human & experimental toxicology.
2012 Oct; 31(10):1050-5. doi:
10.1177/0960327112459205. [PMID: 23023029] - Shohana Parvin, Ok Ran Lee, Gayathri Sathiyaraj, Altanzul Khorolragchaa, Yu-Jin Kim, Balusamy Sri Renuka Devi, Deok-Chun Yang. Interrelationship between calmodulin (CaM) and H2O2 in abscisic acid-induced antioxidant defense in the seedlings of Panax ginseng.
Molecular biology reports.
2012 Jul; 39(7):7327-38. doi:
10.1007/s11033-012-1564-5. [PMID: 22307798] - Mariusz K Szymanski, Rudolf A de Boer, Gerjan J Navis, Wiek H van Gilst, Hans L Hillege. Animal models of cardiorenal syndrome: a review.
Heart failure reviews.
2012 May; 17(3):411-20. doi:
10.1007/s10741-011-9279-6. [PMID: 21909828] - Jinglong Jiang, Miao Su, Liyan Wang, Chengjin Jiao, Zhengxi Sun, Wei Cheng, Fengmin Li, Chongying Wang. Exogenous hydrogen peroxide reversibly inhibits root gravitropism and induces horizontal curvature of primary root during grass pea germination.
Plant physiology and biochemistry : PPB.
2012 Apr; 53(?):84-93. doi:
10.1016/j.plaphy.2012.01.017. [PMID: 22342943] - Yuan-Ting Hsu, Tse-Min Lee. Modulation of gene expression of carotene biosynthesis-related protein by photosynthetic electron transport for the acclimation of intertidal macroalga Ulva fasciata to hypersalinity and excess light.
Physiologia plantarum.
2012 Mar; 144(3):225-37. doi:
10.1111/j.1399-3054.2011.01547.x. [PMID: 22122736] - Jin-Yi Han, Sun-Young Ahn, Chung-Soo Kim, Sung-Kwang Yoo, Si-Kwan Kim, Hyoung-Chun Kim, Jin Tae Hong, Ki-Wan Oh. Protection of apigenin against kainate-induced excitotoxicity by anti-oxidative effects.
Biological & pharmaceutical bulletin.
2012; 35(9):1440-6. doi:
10.1248/bpb.b110686. [PMID: 22975493] - Onur Cil, Mert Ertunc, Kadri Safak Gucer, Fatih Ozaltin, Alper Bektas Iskit, Rustu Onur. Endothelial dysfunction and increased responses to renal nerve stimulation in rat kidneys during rhabdomyolysis-induced acute renal failure: role of hydroxyl radical.
Renal failure.
2012; 34(2):211-20. doi:
10.3109/0886022x.2011.643389. [PMID: 22229548] - Hsiang-Hao Hsu, Sigrid Hoffmann, Giovana S Di Marco, Nicole Endlich, Jasna Peter-Katalinić, Thomas Weide, Hermann Pavenstädt. Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis.
Kidney international.
2011 Nov; 80(9):959-969. doi:
10.1038/ki.2011.250. [PMID: 21814176] - El-Sayed M El-Sayed, Abdel-Aziz H Abdel-Aziz, Samira Saleh, Ahmed S Saad. The chemopreventive effect of dimethylthiourea against carmustine-induced myelotoxicity in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2011 Sep; 49(9):1965-9. doi:
10.1016/j.fct.2011.05.007. [PMID: 21620922] - Alessandra Tisi, Rodolfo Federico, Sandra Moreno, Sergio Lucretti, Panagiotis N Moschou, Kalliopi A Roubelakis-Angelakis, Riccardo Angelini, Alessandra Cona. Perturbation of polyamine catabolism can strongly affect root development and xylem differentiation.
Plant physiology.
2011 Sep; 157(1):200-15. doi:
10.1104/pp.111.173153. [PMID: 21746808] - Masaru Yukihiro, Takuya Hiramatsu, Tomonori Kawano. Lethal impacts of cigarette smoke in cultured tobacco cells.
Tobacco induced diseases.
2011 Jul; 9(?):8. doi:
10.1186/1617-9625-9-8. [PMID: 21762527] - Maik Böhmer, Julian I Schroeder. Quantitative transcriptomic analysis of abscisic acid-induced and reactive oxygen species-dependent expression changes and proteomic profiling in Arabidopsis suspension cells.
The Plant journal : for cell and molecular biology.
2011 Jul; 67(1):105-18. doi:
10.1111/j.1365-313x.2011.04579.x. [PMID: 21426425] - Qianzi Yang, Hui Dong, Jiao Deng, Qiang Wang, Ruidong Ye, Xuying Li, Sheng Hu, Hailong Dong, Lize Xiong. Sevoflurane preconditioning induces neuroprotection through reactive oxygen species-mediated up-regulation of antioxidant enzymes in rats.
Anesthesia and analgesia.
2011 Apr; 112(4):931-7. doi:
10.1213/ane.0b013e31820bcfa4. [PMID: 21385986] - Calpurnia Jayakumar, Riyaz Mohamed, Punithavathi Vilapakkam Ranganathan, Ganesan Ramesh. Intracellular kinases mediate increased translation and secretion of netrin-1 from renal tubular epithelial cells.
PloS one.
2011; 6(10):e26776. doi:
10.1371/journal.pone.0026776. [PMID: 22046354] - Cimen Karasu. Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment.
The open cardiovascular medicine journal.
2010 Nov; 4(?):240-56. doi:
10.2174/1874192401004010240. [PMID: 21270942] - Yingli Yang, Xueling Wei, Jin Lu, Jia You, Wenrui Wang, Ruxia Shi. Lead-induced phytotoxicity mechanism involved in seed germination and seedling growth of wheat (Triticum aestivum L.).
Ecotoxicology and environmental safety.
2010 Nov; 73(8):1982-7. doi:
10.1016/j.ecoenv.2010.08.041. [PMID: 20833428] - Toby K McGovern, William S Powell, Brian J Day, Carl W White, Karuthapillai Govindaraju, Harry Karmouty-Quintana, Normand Lavoie, Ju Jing Tan, James G Martin. Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma.
Respiratory research.
2010 Oct; 11(?):138. doi:
10.1186/1465-9921-11-138. [PMID: 20925946] - Lichao Hou, Keliang Xie, Mingzhe Qin, Daorong Peng, Shirong Ma, Lei Shang, Nan Li, Shuzhi Li, Genlin Ji, Yan Lu, Lize Xiong. Effects of reactive oxygen species scavenger on the protective action of 100\% oxygen treatment against sterile inflammation in mice.
Shock (Augusta, Ga.).
2010 Jun; 33(6):646-54. doi:
10.1097/shk.0b013e3181c1b5d4. [PMID: 19789462] - Nita Sachan, Dennis T Rogers, Kil-Young Yun, John M Littleton, Deane L Falcone. Reactive oxygen species regulate alkaloid metabolism in undifferentiated N. tabacum cells.
Plant cell reports.
2010 May; 29(5):437-48. doi:
10.1007/s00299-010-0833-9. [PMID: 20217418] - V Mohan Murali Achary, Brahma B Panda. Aluminium-induced DNA damage and adaptive response to genotoxic stress in plant cells are mediated through reactive oxygen intermediates.
Mutagenesis.
2010 Mar; 25(2):201-9. doi:
10.1093/mutage/gep063. [PMID: 19955331] - Pierre Watcho, Roman Stavniichuk, David M Ribnicky, Ilya Raskin, Irina G Obrosova. High-fat diet-induced neuropathy of prediabetes and obesity: effect of PMI-5011, an ethanolic extract of Artemisia dracunculus L.
Mediators of inflammation.
2010; 2010(?):268547. doi:
10.1155/2010/268547. [PMID: 20396384] - Shang-Pin Liu, Chien-Yu Chang, Wen-Hung Huang, Yaw-Syan Fu, David Chao, Hung-Tu Huang. Dimethylthiourea pretreatment inhibits endotoxin-induced compound exocytosis in goblet cells and plasma leakage of rat small intestine.
Journal of electron microscopy.
2010; 59(2):127-39. doi:
10.1093/jmicro/dfp049. [PMID: 19825851] - Helga Stopper, Nicole Schupp, Gholamreza Fazeli, Barbara Dietel, Nina Queisser, Susanne Walitza, Manfred Gerlach. Genotoxicity of the neurotransmitter dopamine in vitro.
Toxicology in vitro : an international journal published in association with BIBRA.
2009 Jun; 23(4):640-6. doi:
10.1016/j.tiv.2009.03.001. [PMID: 19285549] - Tung-Lung Tsai, Shyue-Yih Chang, Ching-Yin Ho, Yu Ru Kou. Role of ATP in the ROS-mediated laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats.
Journal of applied physiology (Bethesda, Md. : 1985).
2009 May; 106(5):1584-92. doi:
10.1152/japplphysiol.91517.2008. [PMID: 19246655] - Ming-Shiuan Sung, Yi-Ting Hsu, Yuan-Ting Hsu, Tzure-Meng Wu, Tse-Min Lee. Hypersalinity and hydrogen peroxide upregulation of gene expression of antioxidant enzymes in Ulva fasciata against oxidative stress.
Marine biotechnology (New York, N.Y.).
2009 Mar; 11(2):199-209. doi:
10.1007/s10126-008-9134-5. [PMID: 18758860] - Xiao-juan Zong, Da-peng Li, Ling-kun Gu, De-quan Li, Li-xia Liu, Xiao-li Hu. Abscisic acid and hydrogen peroxide induce a novel maize group C MAP kinase gene, ZmMPK7, which is responsible for the removal of reactive oxygen species.
Planta.
2009 Feb; 229(3):485-95. doi:
10.1007/s00425-008-0848-4. [PMID: 19002491] - Wen-Hung Huang, Wei-Ban Chang, Shang-Pin Liu, Jen-Tai Lin, Yaw-Syan Fu, Min-Chi Chang, Hung-Tu Huang. Inhibitory effect of dimethylthiourea on rat urinary bladder inflammation produced by 6-hydroxydopamine application.
Autonomic neuroscience : basic & clinical.
2009 Jan; 145(1-2):44-9. doi:
10.1016/j.autneu.2008.11.003. [PMID: 19059812] - Fan Lin, Haidong Ding, Jinxiang Wang, Hong Zhang, Aying Zhang, Yun Zhang, Mingpu Tan, Wen Dong, Mingyi Jiang. Positive feedback regulation of maize NADPH oxidase by mitogen-activated protein kinase cascade in abscisic acid signalling.
Journal of experimental botany.
2009; 60(11):3221-38. doi:
10.1093/jxb/erp157. [PMID: 19592501] - Kuo Tung Hung, Deng Guo Cheng, Yi Ting Hsu, Ching Huei Kao. Abscisic acid-induced hydrogen peroxide is required for anthocyanin accumulation in leaves of rice seedlings.
Journal of plant physiology.
2008 Aug; 165(12):1280-7. doi:
10.1016/j.jplph.2007.10.008. [PMID: 18160127] - Raymond Farah, Revital Shurtz-Swirski, Olga Lapin. Intensification of oxidative stress and inflammation in type 2 diabetes despite antihyperglycemic treatment.
Cardiovascular diabetology.
2008 Jun; 7(?):20. doi:
10.1186/1475-2840-7-20. [PMID: 18570678] - N A G Santos, C S Catão Bezerra, N M Martins, C Curti, M L P Bianchi, A C Santos. Hydroxyl radical scavenger ameliorates cisplatin-induced nephrotoxicity by preventing oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria.
Cancer chemotherapy and pharmacology.
2008 Jan; 61(1):145-55. doi:
10.1007/s00280-007-0459-y. [PMID: 17396264] - Neife Aparecida Guinaim dos Santos, Nádia Maria Martins, Carlos Curti, Maria de Lourdes Pires Bianchi, Antonio Cardozo dos Santos. Dimethylthiourea protects against mitochondrial oxidative damage induced by cisplatin in liver of rats.
Chemico-biological interactions.
2007 Dec; 170(3):177-86. doi:
10.1016/j.cbi.2007.07.014. [PMID: 17850778] - Kuo Tung Hung, Ching Huei Kao. The participation of hydrogen peroxide in methyl jasmonate-induced NH(4)(+) accumulation in rice leaves.
Journal of plant physiology.
2007 Nov; 164(11):1469-79. doi:
10.1016/j.jplph.2006.10.005. [PMID: 17215059] - Wulin Aerbajinai, Jianqiong Zhu, Zhigang Gao, Kyung Chin, Griffin P Rodgers. Thalidomide induces gamma-globin gene expression through increased reactive oxygen species-mediated p38 MAPK signaling and histone H4 acetylation in adult erythropoiesis.
Blood.
2007 Oct; 110(8):2864-71. doi:
10.1182/blood-2007-01-065201. [PMID: 17620452] - Qiu-Hong Pan, Yan-Jun Zhang, Yan-Yan Liu, Yan-Fang Zhang, Wei-Dong Huang. [Changes in H2O2 and salicylic acid contents as well as plasma membrane H+-ATPase activity and their relations in pea leaves during thermotolerance induction].
Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology.
2007 Oct; 33(5):425-34. doi:
NULL. [PMID: 17960046] - Liyu Xing, Daniel G Remick. Mechanisms of oxidant regulation of monocyte chemotactic protein 1 production in human whole blood and isolated mononuclear cells.
Shock (Augusta, Ga.).
2007 Aug; 28(2):178-85. doi:
10.1097/shk.0b013e3180311cf4. [PMID: 17529908] - Man Jiang, Qingqing Wei, Navjotsin Pabla, Guie Dong, Cong-Yi Wang, Tianxin Yang, Sylvia B Smith, Zheng Dong. Effects of hydroxyl radical scavenging on cisplatin-induced p53 activation, tubular cell apoptosis and nephrotoxicity.
Biochemical pharmacology.
2007 May; 73(9):1499-510. doi:
10.1016/j.bcp.2007.01.010. [PMID: 17291459] - Elif Erkan, Prasad Devarajan, George J Schwartz. Mitochondria are the major targets in albumin-induced apoptosis in proximal tubule cells.
Journal of the American Society of Nephrology : JASN.
2007 Apr; 18(4):1199-208. doi:
10.1681/asn.2006040407. [PMID: 17360944] - Prosper M'Bemba-Meka, Nicole Lemieux, Saroj K Chakrabarti. Role of oxidative stress and intracellular calcium in nickel carbonate hydroxide-induced sister-chromatid exchange, and alterations in replication index and mitotic index in cultured human peripheral blood lymphocytes.
Archives of toxicology.
2007 Feb; 81(2):89-99. doi:
10.1007/s00204-006-0128-7. [PMID: 16826409] - Hiromi Hiruma, Takashi Katakura, Tamie Takenami, Satoshi Igawa, Maho Kanoh, Takao Fujimura, Tadashi Kawakami. Vesicle disruption, plasma membrane bleb formation, and acute cell death caused by illumination with blue light in acridine orange-loaded malignant melanoma cells.
Journal of photochemistry and photobiology. B, Biology.
2007 Jan; 86(1):1-8. doi:
10.1016/j.jphotobiol.2006.08.003. [PMID: 16982198] - Andrea Kramer, Mabel van den Hoven, Angelique Rops, Tessa Wijnhoven, Lambert van den Heuvel, Joost Lensen, Toin van Kuppevelt, Harry van Goor, Johan van der Vlag, Gerjan Navis, Jo H M Berden. Induction of glomerular heparanase expression in rats with adriamycin nephropathy is regulated by reactive oxygen species and the renin-angiotensin system.
Journal of the American Society of Nephrology : JASN.
2006 Sep; 17(9):2513-20. doi:
10.1681/asn.2006020184. [PMID: 16899518] - Kentaro Ohishi, Xiao Mei Zhang, Shinichi Moriwaki, Tadahisa Hiramitsu, Seiichi Matsugo. In the presence of ferritin, visible light induces lipid peroxidation of the porcine photoreceptor outer segment.
Free radical research.
2006 Aug; 40(8):799-807. doi:
10.1080/10715760600555027. [PMID: 17015258] - Yasuhiro Masubuchi, Mamiko Kawasaki, Toshiharu Horie. Down-regulation of hepatic cytochrome P450 enzymes associated with cisplatin-induced acute renal failure in male rats.
Archives of toxicology.
2006 Jun; 80(6):347-53. doi:
10.1007/s00204-006-0079-z. [PMID: 16485119] - Oscar A Bizzozero, Jennifer L Ziegler, Gisela De Jesus, Federico Bolognani. Acute depletion of reduced glutathione causes extensive carbonylation of rat brain proteins.
Journal of neuroscience research.
2006 Mar; 83(4):656-67. doi:
10.1002/jnr.20771. [PMID: 16447283] - Ying Yang, Zhenlong Wu, Yue Chen, Jian Qiao, Mingyu Gao, Jianmin Yuan, Wei Nie, Yuming Guo. Magnesium deficiency enhances hydrogen peroxide production and oxidative damage in chick embryo hepatocyte in vitro.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine.
2006 Feb; 19(1):71-81. doi:
10.1007/s10534-005-6898-1. [PMID: 16502333] - Xiuli Hu, Mingyi Jiang, Aying Zhang, Jun Lu. Abscisic acid-induced apoplastic H2O2 accumulation up-regulates the activities of chloroplastic and cytosolic antioxidant enzymes in maize leaves.
Planta.
2005 Dec; 223(1):57-68. doi:
10.1007/s00425-005-0068-0. [PMID: 16049674] - T Sudhakar Babu, Sridevi Tripuranthakam, Bruce M Greenberg. Biochemical responses of the aquatic higher plant Lemna gibba to a mixture of copper and 1,2-dihydroxyanthraquinone: synergistic toxicity via reactive oxygen species.
Environmental toxicology and chemistry.
2005 Dec; 24(12):3030-6. doi:
10.1897/05-073r.1. [PMID: 16445081] - Takaaki Oteki, Sohji Nagase, Hidekatsu Yokoyama, Hiroaki Ohya, Takao Akatsuka, Mika Tada, Atsushi Ueda, Aki Hirayama, Akio Koyama. Normalizing renal reducing ability prevents adriamycin-induced proteinuria.
Biochemical and biophysical research communications.
2005 Nov; 337(1):48-51. doi:
10.1016/j.bbrc.2005.08.266. [PMID: 16171782] - Chia-Tai Shiu, Tse-Min Lee. Ultraviolet-B-induced oxidative stress and responses of the ascorbate-glutathione cycle in a marine macroalga Ulva fasciata.
Journal of experimental botany.
2005 Nov; 56(421):2851-65. doi:
10.1093/jxb/eri277. [PMID: 16157654] - Prosper M'Bemba-Meka, Nicole Lemieux, Saroj K Chakrabarti. Nickel compound-induced DNA single-strand breaks in chromosomal and nuclear chromatin in human blood lymphocytes in vitro: role of oxidative stress and intracellular calcium.
Mutation research.
2005 Oct; 586(2):124-37. doi:
10.1016/j.mrgentox.2005.06.001. [PMID: 16099703] - Kuo Tung Hung, Ching Huei Kao. Hydrogen peroxide is required for abscisic acid-induced NH4+ accumulation in rice leaves.
Journal of plant physiology.
2005 Sep; 162(9):1022-9. doi:
10.1016/j.jplph.2004.11.007. [PMID: 16173463] - Yoshiko Kawai, Yuka Kohda, Takaaki Kodawara, Munekazu Gemba. Protective effect of a protein kinase inhibitor on cellular injury induced by cephaloridine in the porcine kidney cell line LLC-PK(1).
The Journal of toxicological sciences.
2005 Aug; 30(3):157-63. doi:
10.2131/jts.30.157. [PMID: 16141650] - Wuling Lin, Xiangyang Hu, Wenqing Zhang, W John Rogers, Weiming Cai. Hydrogen peroxide mediates defence responses induced by chitosans of different molecular weights in rice.
Journal of plant physiology.
2005 Aug; 162(8):937-44. doi:
10.1016/j.jplph.2004.10.003. [PMID: 16146320] - Yu-Chang Tsai, Chwan-Yang Hong, Li-Fei Liu, Ching Huei Kao. Expression of ascorbate peroxidase and glutathione reductase in roots of rice seedlings in response to NaCl and H2O2.
Journal of plant physiology.
2005 Mar; 162(3):291-9. doi:
10.1016/j.jplph.2004.06.004. [PMID: 15832681] - Ping-Chia Li, Sheng-Chung Li, Yuan-Ju Lin, Jin-Tung Liang, Chiang-Ting Chien, Chen-Fu Shaw. Thoracic vagal efferent nerve stimulation evokes substance P-induced early airway bronchonstriction and late proinflammatory and oxidative injury in the rat respiratory tract.
Journal of biomedical science.
2005; 12(4):671-81. doi:
10.1007/s11373-005-7892-x. [PMID: 16078002] - Kuo Tung Hung, Ching Huei Kao. Hydrogen peroxide is necessary for abscisic acid-induced senescence of rice leaves.
Journal of plant physiology.
2004 Dec; 161(12):1347-57. doi:
10.1016/j.jplph.2004.05.011. [PMID: 15658805] - M Kadkhodaee, A Qasemi. Inhibition of inducible nitric oxide synthase reduces lipopolysaccharide-induced renal injury in the rat.
Clinical and experimental pharmacology & physiology.
2004 Dec; 31(12):842-6. doi:
10.1111/j.1440-1681.2004.04096.x. [PMID: 15659046] - Yolanda I Chirino, Rogelio Hernández-Pando, José Pedraza-Chaverrí. Peroxynitrite decomposition catalyst ameliorates renal damage and protein nitration in cisplatin-induced nephrotoxicity in rats.
BMC pharmacology.
2004 Sep; 4(?):20. doi:
10.1186/1471-2210-4-20. [PMID: 15458572] - Xiangyang Hu, Steven J Neill, Jianying Fang, Weiming Cai, Zhangcheng Tang. Mitogen-activated protein kinases mediate the oxidative burst and saponin synthesis induced by chitosan in cell cultures of Panax ginseng.
Science in China. Series C, Life sciences.
2004 Aug; 47(4):303-12. doi:
10.1360/03yc0074. [PMID: 15493471] - Takuya Kishi, Yoshitaka Hirooka, Yoshikuni Kimura, Koji Ito, Hiroaki Shimokawa, Akira Takeshita. Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats.
Circulation.
2004 May; 109(19):2357-62. doi:
10.1161/01.cir.0000128695.49900.12. [PMID: 15117836] - Kent Doi, Yoshifumi Suzuki, Akihide Nakao, Toshiro Fujita, Eisei Noiri. Radical scavenger edaravone developed for clinical use ameliorates ischemia/reperfusion injury in rat kidney.
Kidney international.
2004 May; 65(5):1714-23. doi:
10.1111/j.1523-1755.2004.00567.x. [PMID: 15086910] - José Pedraza-Chaverrí, Diana Barrera, Perla D Maldonado, Yolanda I Chirino, Norma A Macías-Ruvalcaba, Omar N Medina-Campos, Leticia Castro, Marcos I Salcedo, Rogelio Hernández-Pando. S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo.
BMC clinical pharmacology.
2004 Apr; 4(?):5. doi:
10.1186/1472-6904-4-5. [PMID: 15119956] - Aditi A Kapasi, Salvatore A Coscia, Manish P Pandya, Pravin C Singhal. Morphine modulates HIV-1 gp160-induced murine macrophage and human monocyte apoptosis by disparate ways.
Journal of neuroimmunology.
2004 Mar; 148(1-2):86-96. doi:
10.1016/j.jneuroim.2003.11.015. [PMID: 14975589] - Isaac Ginsburg, Milu Sadovnic, Miriam Oron, Ron Kohen. Novel chemiluminescence-inducing cocktails, part I: the role in light emission of combinations of luminal with SIN-1, selenite, albumin, glucose oxidase and Co2+.
Inflammopharmacology.
2004; 12(4):289-303. doi:
10.1163/1568560043696263. [PMID: 15901411] - T Sudhakar Babu, Tariq A Akhtar, Mark A Lampi, Sridevi Tripuranthakam, D George Dixon, Bruce M Greenberg. Similar stress responses are elicited by copper and ultraviolet radiation in the aquatic plant Lemna gibba: implication of reactive oxygen species as common signals.
Plant & cell physiology.
2003 Dec; 44(12):1320-9. doi:
10.1093/pcp/pcg160. [PMID: 14701927] - Su Mi Baek, Chae Hwa Kwon, Jae Ho Kim, Jae Suk Woo, Jin Sup Jung, Yong Keun Kim. Differential roles of hydrogen peroxide and hydroxyl radical in cisplatin-induced cell death in renal proximal tubular epithelial cells.
The Journal of laboratory and clinical medicine.
2003 Sep; 142(3):178-86. doi:
10.1016/s0022-2143(03)00111-2. [PMID: 14532906] - Kazuhiko Tsuruya, Masanori Tokumoto, Toshiharu Ninomiya, Makoto Hirakawa, Kohsuke Masutani, Masatomo Taniguchi, Kyoichi Fukuda, Hidetoshi Kanai, Hideki Hirakata, Mitsuo Iida. Antioxidant ameliorates cisplatin-induced renal tubular cell death through inhibition of death receptor-mediated pathways.
American journal of physiology. Renal physiology.
2003 Aug; 285(2):F208-18. doi:
10.1152/ajprenal.00311.2002. [PMID: 12684229] - William C McAmis, Richard C Schaeffer, John W Baynes, Matthew B Wolf. Menadione causes endothelial barrier failure by a direct effect on intracellular thiols, independent of reactive oxidant production.
Biochimica et biophysica acta.
2003 Jun; 1641(1):43-53. doi:
10.1016/s0167-4889(03)00063-6. [PMID: 12788228] - H Ramiro Lascano, Leonardo M Casano, Mercedes Martín, Bartolomé Sabater. The activity of the chloroplastic Ndh complex is regulated by phosphorylation of the NDH-F subunit.
Plant physiology.
2003 May; 132(1):256-62. doi:
10.1104/pp.103.020321. [PMID: 12746530] - Sung Min Park, Hyun Chul Jung, Im Soo Koak, Ha Yun Na, Jae Suk Woo, Jin Sup Jung, Yong Keun Kim. Oxidant-induced cell death in renal epithelial cells: differential effects of inorganic and organic hydroperoxides.
Pharmacology & toxicology.
2003 Jan; 92(1):43-50. doi:
10.1034/j.1600-0773.2003.920108.x. [PMID: 12710597] - Małgorzata Zielińska, Michael Gülden, Hasso Seibert. Effects of quercetin and quercetin-3-O-glycosides on oxidative damage in rat C6 glioma cells.
Environmental toxicology and pharmacology.
2003 Jan; 13(1):47-53. doi:
10.1016/s1382-6689(02)00129-1. [PMID: 21782648] - Mingyi Jiang, Jianhua Zhang. Water stress-induced abscisic acid accumulation triggers the increased generation of reactive oxygen species and up-regulates the activities of antioxidant enzymes in maize leaves.
Journal of experimental botany.
2002 Dec; 53(379):2401-10. doi:
10.1093/jxb/erf090. [PMID: 12432032] - Virginia Garretón, Jorge Carpinelli, Xavier Jordana, Loreto Holuigue. The as-1 promoter element is an oxidative stress-responsive element and salicylic acid activates it via oxidative species.
Plant physiology.
2002 Nov; 130(3):1516-26. doi:
10.1104/pp.009886. [PMID: 12428016] - Richard A Zager, Ali C M Johnson, Sherry Y Hanson, Haimanot Wasse. Parenteral iron formulations: a comparative toxicologic analysis and mechanisms of cell injury.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2002 Jul; 40(1):90-103. doi:
10.1053/ajkd.2002.33917. [PMID: 12087566] - Shannon D McClintock, Gerd O Till, Milton G Smith, Peter A Ward. Protection from half-mustard-gas-induced acute lung injury in the rat.
Journal of applied toxicology : JAT.
2002 Jul; 22(4):257-62. doi:
10.1002/jat.856. [PMID: 12210543] - Ben-Zhan Zhu, William E Antholine, Balz Frei. Thiourea protects against copper-induced oxidative damage by formation of a redox-inactive thiourea-copper complex.
Free radical biology & medicine.
2002 Jun; 32(12):1333-8. doi:
10.1016/s0891-5849(02)00847-x. [PMID: 12057771] - Dana K Vaughan, Jenny L Nemke, Steven J Fliesler, Ruth M Darrow, Daniel T Organisciak. Evidence for a circadian rhythm of susceptibility to retinal light damage.
Photochemistry and photobiology.
2002 May; 75(5):547-53. doi:
10.1562/0031-8655(2002)075<0547:efacro>2.0.co;2. [PMID: 12017483] - Marina Morigi, Daniela Macconi, Carla Zoja, Roberta Donadelli, Simona Buelli, Cristina Zanchi, Marina Ghilardi, Giuseppe Remuzzi. Protein overload-induced NF-kappaB activation in proximal tubular cells requires H(2)O(2) through a PKC-dependent pathway.
Journal of the American Society of Nephrology : JASN.
2002 May; 13(5):1179-89. doi:
NULL. [PMID: 11961005] - Jiiang-Huei Jeng, Shiao-Yun Chen, Chang-Hui Liao, Yuan-Yii Tung, Bor-Ru Lin, Liang-Jiunn Hahn, Mei-Chi Chang. Modulation of platelet aggregation by areca nut and betel leaf ingredients: roles of reactive oxygen species and cyclooxygenase.
Free radical biology & medicine.
2002 May; 32(9):860-71. doi:
10.1016/s0891-5849(02)00749-9. [PMID: 11978487] - M C Chang, Y S Ho, J J Lee, S H Kok, L J Hahn, J H Jeng. Prevention of the areca nut extract-induced unscheduled DNA synthesis of gingival keratinocytes by vitamin C and thiol compounds.
Oral oncology.
2002 Apr; 38(3):258-65. doi:
10.1016/s1368-8375(01)00053-7. [PMID: 11978548] - Yong Keun Kim, Sung Keun Lee, Mi Suk Ha, Jae Suk Woo, Jin Sup Jung. Differential role of reactive oxygen species in chemical hypoxia-induced cell injury in opossum kidney cells and rabbit renal cortical slices.
Experimental nephrology.
2002; 10(4):275-84. doi:
10.1159/000063702. [PMID: 12097831] - Stefan Greiber, Barbara Müller, Petra Daemisch, Hermann Pavenstädt. Reactive oxygen species alter gene expression in podocytes: induction of granulocyte macrophage-colony-stimulating factor.
Journal of the American Society of Nephrology : JASN.
2002 Jan; 13(1):86-95. doi:
10.1681/asn.v13186. [PMID: 11752025] - Y W Lee, M S Ha, Y K Kim. Role of reactive oxygen species and glutathione in inorganic mercury-induced injury in human glioma cells.
Neurochemical research.
2001 Nov; 26(11):1187-93. doi:
10.1023/a:1013955020515. [PMID: 11874199] - R Bruck, H Shirin, H Aeed, Z Matas, A Hochman, M Pines, Y Avni. Prevention of hepatic cirrhosis in rats by hydroxyl radical scavengers.
Journal of hepatology.
2001 Oct; 35(4):457-64. doi:
10.1016/s0168-8278(01)00163-5. [PMID: 11682029] - H Tsutsui, T Ide, S Hayashidani, N Suematsu, T Shiomi, J Wen, Nakamura Ki, K Ichikawa, H Utsumi, A Takeshita. Enhanced generation of reactive oxygen species in the limb skeletal muscles from a murine infarct model of heart failure.
Circulation.
2001 Jul; 104(2):134-6. doi:
10.1161/01.cir.104.2.134. [PMID: 11447074] - U Pattanaik, K Prasad. Reactive oxygen species and endotoxic shock: effect of dimethylthiourea.
Journal of cardiovascular pharmacology and therapeutics.
2001 Jul; 6(3):273-85. doi:
10.1177/107424840100600308. [PMID: 11584334] - N Nahar, H Shah, J Siu, R Colvin, M Bhaskaran, R Ranjan, J D Wagner, P C Singhal. Dialysis membrane-induced neutrophil apoptosis is mediated through free radicals.
Clinical nephrology.
2001 Jul; 56(1):52-9. doi:
NULL. [PMID: 11499659] - G Wolf, U Wenzel, T Hannken, R A Stahl. Angiotensin II induces p27(Kip1) expression in renal tubules in vivo: role of reactive oxygen species.
Journal of molecular medicine (Berlin, Germany).
2001 Jul; 79(7):382-9. doi:
10.1007/s001090100241. [PMID: 11466560] - V Grishko, M Solomon, G L Wilson, S P LeDoux, M N Gillespie. Oxygen radical-induced mitochondrial DNA damage and repair in pulmonary vascular endothelial cell phenotypes.
American journal of physiology. Lung cellular and molecular physiology.
2001 Jun; 280(6):L1300-8. doi:
10.1152/ajplung.2001.280.6.l1300. [PMID: 11350811] - M G Schlag, K A Harris, R F Potter. Role of leukocyte accumulation and oxygen radicals in ischemia-reperfusion-induced injury in skeletal muscle.
American journal of physiology. Heart and circulatory physiology.
2001 Apr; 280(4):H1716-21. doi:
10.1152/ajpheart.2001.280.4.h1716. [PMID: 11247784] - Y W Lee, M S Ha, Y K Kim. H2O2-induced cell death in human glioma cells: role of lipid peroxidation and PARP activation.
Neurochemical research.
2001 Apr; 26(4):337-43. doi:
10.1023/a:1010993428770. [PMID: 11495343] - L M Casano, M Martín, B Sabater. Hydrogen peroxide mediates the induction of chloroplastic Ndh complex under photooxidative stress in barley.
Plant physiology.
2001 Mar; 125(3):1450-8. doi:
10.1104/pp.125.3.1450. [PMID: 11244124] - Y Ding, H C Gonick, N D Vaziri, K Liang, L Wei. Lead-induced hypertension. III. Increased hydroxyl radical production.
American journal of hypertension.
2001 Feb; 14(2):169-73. doi:
10.1016/s0895-7061(00)01248-6. [PMID: 11243309] - V Sanwal, M Pandya, M Bhaskaran, N Franki, K Reddy, G Ding, A Kapasi, E Valderrama, P C Singhal. Puromycin aminonucleoside induces glomerular epithelial cell apoptosis.
Experimental and molecular pathology.
2001 Feb; 70(1):54-64. doi:
10.1006/exmp.2000.2345. [PMID: 11170791] - S Ueno, T Kashimoto, N Susa, Y Furukawa, M Ishii, K Yokoi, M Yasuno, Y F Sasaki, J Ueda, Y Nishimura, M Sugiyama. Detection of dichromate (VI)-induced DNA strand breaks and formation of paramagnetic chromium in multiple mouse organs.
Toxicology and applied pharmacology.
2001 Jan; 170(1):56-62. doi:
10.1006/taap.2000.9081. [PMID: 11141356] - M Sakai, T Tsukada, R C Harris. Oxidant stress activates AP-1 and heparin-binding epidermal growth factor-like growth factor transcription in renal epithelial cells.
Experimental nephrology.
2001; 9(1):28-39. doi:
10.1159/000020705. [PMID: 11053978]