4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-ol (BioDeep_00000780410)

   


代谢物信息卡片


(4Ar,10bR)-rel-4-Propyl-2,3,4,4a,5,10b-hexahydrochromeno[4,3-b][1,4]oxazin-9-ol

化学式: C14H19NO3 (249.1364864)
中文名称: (+)-PD 128907 盐酸盐
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCN1CCOC2C1COC3=C2C=C(C=C3)O
InChI: InChI=1S/C14H19NO3/c1-2-5-15-6-7-17-14-11-8-10(16)3-4-13(11)18-9-12(14)15/h3-4,8,12,14,16H,2,5-7,9H2,1H3

描述信息

D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018491 - Dopamine Agonists
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants

同义名列表

3 个代谢物同义名

(4Ar,10bR)-rel-4-Propyl-2,3,4,4a,5,10b-hexahydrochromeno[4,3-b][1,4]oxazin-9-ol; 4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-ol; 4-Propyl-3,4,4a,10b-tetrahydro-2h,5h-chromeno[4,3-b][1,4]oxazin-9-ol



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Xinjian Chen, Yukai Liu, Wei E Wang, Caiyu Chen, Hongmei Ren, Shuo Zheng, Lin Zhou, Chunyu Zeng. Effect of D3 dopamine receptor on dopamine D4 receptor expression and function in renal proximal tubule cells from Wistar-Kyoto rats and spontaneously hypertensive rats. Journal of hypertension. 2016 08; 34(8):1599-606. doi: 10.1097/hjh.0000000000000986. [PMID: 27254310]
  • Zhen Wang, Weiwei Guan, Yu Han, Hongmei Ren, Xiaofeng Tang, Hui Zhang, Yukai Liu, Jinjuan Fu, Duofen He, Laureano D Asico, Pedro A Jose, Lin Zhou, Liyong Chen, Chunyu Zeng. Stimulation of Dopamine D3 Receptor Attenuates Renal Ischemia-Reperfusion Injury via Increased Linkage With Gα12. Transplantation. 2015 Nov; 99(11):2274-84. doi: 10.1097/tp.0000000000000762. [PMID: 25989500]
  • Jose R Eguibar, Ma del Carmen Cortes, Manuel Lara-Lozano, Diana M Mendiola. Dopaminergic D2-like agonists produce yawning in the myelin mutant taiep and Sprague-Dawley rats. Pharmacology, biochemistry, and behavior. 2012 Jul; 102(1):118-23. doi: 10.1016/j.pbb.2012.03.020. [PMID: 22497991]
  • Hefei Huang, Hongmei Ren, Caiyu Chen, Xiaoyan Wang, Jian Yang, Yu Han, Duofen He, Lin Zhou, Laureano D Asico, Pedro A Jose, Chunyu Zeng. D3 dopamine receptor regulation of D5 receptor expression and function in renal proximal tubule cells. Hypertension research : official journal of the Japanese Society of Hypertension. 2012 Jun; 35(6):639-47. doi: 10.1038/hr.2012.11. [PMID: 22297482]
  • Shu-Ling Liang, Jenn-Tser Pan. An endogenous dopaminergic tone acting on dopamine D3 receptors may be involved in diurnal changes of tuberoinfundibular dopaminergic neuron activity and prolactin secretion in estrogen-primed ovariectomized rats. Brain research bulletin. 2012 Feb; 87(2-3):334-9. doi: 10.1016/j.brainresbull.2011.11.018. [PMID: 22155687]
  • Ye Zhang, Chunjiang Fu, Laureano D Asico, Van Anthony M Villar, Hongmei Ren, Duofen He, Zhen Wang, Jian Yang, Pedro A Jose, Chunyu Zeng. Role of Gα(12)- and Gα(13)-protein subunit linkage of D(3) dopamine receptors in the natriuretic effect of D(3) dopamine receptor in kidney. Hypertension research : official journal of the Japanese Society of Hypertension. 2011 Sep; 34(9):1011-6. doi: 10.1038/hr.2011.70. [PMID: 21633357]
  • Changqing Yu, Zhiwei Yang, Hongmei Ren, Yie Zhang, Yu Han, Duofen He, Quansheng Lu, Xiaoyan Wang, Xukai Wang, Chengming Yang, Laureano D Asico, Ulrich Hopfer, Gilbert M Eisner, Pedro A Jose, Chunyu Zeng. D3 dopamine receptor regulation of ETB receptors in renal proximal tubule cells from WKY and SHRs. American journal of hypertension. 2009 Aug; 22(8):877-83. doi: 10.1038/ajh.2009.80. [PMID: 19390510]
  • Elizabeth A Bolan, Bronwyn Kivell, Vanaja Jaligam, Murat Oz, Lankupalle D Jayanthi, Yang Han, Namita Sen, Eneki Urizar, Ivone Gomes, Lakshmi A Devi, Sammanda Ramamoorthy, Jonathan A Javitch, Agustin Zapata, Toni S Shippenberg. D2 receptors regulate dopamine transporter function via an extracellular signal-regulated kinases 1 and 2-dependent and phosphoinositide 3 kinase-independent mechanism. Molecular pharmacology. 2007 May; 71(5):1222-32. doi: 10.1124/mol.106.027763. [PMID: 17267664]
  • Chunyu Zeng, Yan Liu, Zheng Wang, Duofen He, Lan Huang, Peiying Yu, Shaopeng Zheng, John E Jones, Laureano D Asico, Ulrich Hopfer, Gilbert M Eisner, Robin A Felder, Pedro A Jose. Activation of D3 dopamine receptor decreases angiotensin II type 1 receptor expression in rat renal proximal tubule cells. Circulation research. 2006 Sep; 99(5):494-500. doi: 10.1161/01.res.0000240500.96746.ec. [PMID: 16902178]
  • Chunyu Zeng, Zheng Wang, Hewang Li, Peiying Yu, Shaopeng Zheng, Lijuan Wu, Laureano D Asico, Ulrich Hopfer, Gilbert M Eisner, Robin A Felder, Pedro A Jose. D3 dopamine receptor directly interacts with D1 dopamine receptor in immortalized renal proximal tubule cells. Hypertension (Dallas, Tex. : 1979). 2006 Mar; 47(3):573-9. doi: 10.1161/01.hyp.0000199983.24674.83. [PMID: 16401764]
  • R A Durham, M J Eaton, K E Moore, K J Lookingland. Effects of selective activation of dopamine D2 and D3 receptors on prolactin secretion and the activity of tuberoinfundibular dopamine neurons. European journal of pharmacology. 1997 Sep; 335(1):37-42. doi: 10.1016/s0014-2999(97)01179-5. [PMID: 9371544]