m-3M3FBS (BioDeep_00000780400)
代谢物信息卡片
化学式: C16H16F3NO2S (343.08537920000003)
中文名称: 2,4,6-三甲基-N-[3-(三氟甲基)苯基]苯磺酰胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC(=C(C(=C1)C)S(=O)(=O)NC2=CC=CC(=C2)C(F)(F)F)C
InChI: InChI=1S/C16H16F3NO2S/c1-10-7-11(2)15(12(3)8-10)23(21,22)20-14-6-4-5-13(9-14)16(17,18)19/h4-9,20H,1-3H3
描述信息
m-3M3FBS is a potent phospholipase C (PLC) activator. m-3M3FBS stimulates superoxide generation in human neutrophils, upregulates intracellular calcium concentration, and stimulates inositol phosphate generation in various cell lines. m-3M3FBS induces monocytic leukemia cell apoptosis[1][2][3].
同义名列表
1 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:92167
- PubChem: 761523
- ChEMBL: CHEMBL1394135
- CAS: 200933-14-8
- medchemexpress: HY-19619
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Abass Al-Momany, Laiji Li, R Todd Alexander, Barbara J Ballermann. Clustered PI(4,5)P₂ accumulation and ezrin phosphorylation in response to CLIC5A.
Journal of cell science.
2014 Dec; 127(Pt 24):5164-78. doi:
10.1242/jcs.147744. [PMID: 25344252] - Tomoka Morita, Muneyoshi Okada, Yukio Hara, Hideyuki Yamawaki. Mechanisms underlying impairment of endothelium-dependent relaxation by fetal bovine serum in organ-cultured rat mesenteric artery.
European journal of pharmacology.
2011 Oct; 668(3):401-6. doi:
10.1016/j.ejphar.2011.07.040. [PMID: 21854767] - Yi-Chien Fang, Daih-Huang Kuo, Pochuen Shieh, Fu-An Chen, Chun-Chi Kuo, Chung-Ren Jan. Effect of m-3M3FBS on Ca(2+) movement in Madin-Darby canine renal tubular cells.
Human & experimental toxicology.
2009 Oct; 28(10):655-63. doi:
10.1177/0960327109106972. [PMID: 19770166] - Beatriz Fioravanti, Milena De Felice, Cheryl L Stucky, Karen A Medler, Miaw-Chyi Luo, Luis R Gardell, Mohab Ibrahim, T Phil Malan, Henry I Yamamura, Michael H Ossipov, Tamara King, Josephine Lai, Frank Porreca, Todd W Vanderah. Constitutive activity at the cannabinoid CB1 receptor is required for behavioral response to noxious chemical stimulation of TRPV1: antinociceptive actions of CB1 inverse agonists.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2008 Nov; 28(45):11593-602. doi:
10.1523/jneurosci.3322-08.2008. [PMID: 18987195] - Alberto M Díaz Añel. Phospholipase C beta3 is a key component in the Gbetagamma/PKCeta/PKD-mediated regulation of trans-Golgi network to plasma membrane transport.
The Biochemical journal.
2007 Aug; 406(1):157-65. doi:
10.1042/bj20070359. [PMID: 17492941] - Lisa F Horowitz, Wiebke Hirdes, Byung-Chang Suh, Donald W Hilgemann, Ken Mackie, Bertil Hille. Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current.
The Journal of general physiology.
2005 Sep; 126(3):243-62. doi:
10.1085/jgp.200509309. [PMID: 16129772]