Norgestomet (BioDeep_00000778223)
代谢物信息卡片
Norprogesterone
化学式: C23H32O4 (372.2300472)
中文名称: 诺孕美特
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1CC2(C(CCC2(C(=O)C)OC(=O)C)C3C1C4CCC(=O)C=C4CC3)C
InChI: InChI=1S/C23H32O4/c1-13-12-22(4)20(9-10-23(22,14(2)24)27-15(3)25)19-7-5-16-11-17(26)6-8-18(16)21(13)19/h11,13,18-21H,5-10,12H2,1-4H3/t13-,18-,19-,20-,21+,22-,23-/m0/s1
描述信息
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
同义名列表
2 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- John Cavalieri. Effect of treatment of Bos indicus heifers with progesterone 0, 3 and 6 days after follicular aspiration on follicular dynamics and the timing of oestrus and ovulation.
Animal reproduction science.
2018 Jun; 193(?):9-18. doi:
10.1016/j.anireprosci.2018.03.026. [PMID: 29627282] - Anand Kumar Pandey, Gurcharan Singh Dhaliwal, Sarvpreet Singh Ghuman, Jagir Singh, Ajeet Kumar, Sudhir Kumar Agarwal. Impact of norgestomet supplementation during early luteal phase on subsequent luteal profiles and conception rate in buffalo: a preliminary study.
Tropical animal health and production.
2013 Jan; 45(1):293-8. doi:
10.1007/s11250-012-0217-y. [PMID: 22802094] - Massoud Talebkhan Garoussi, Nima Farzaneh, Ehssan Gallehdar, Mehrdad Mohri. Reproductive performance in out-of-breeding season of fatty ewes using implant norgestomet with or without PMSG.
Tropical animal health and production.
2012 Jun; 44(5):965-8. doi:
10.1007/s11250-011-9993-z. [PMID: 22065305] - W Holtz, X Wang, M El-Gayar, P G Knight. The effect of exogenous gonadotropins on ovarian function in goats actively immunized against inhibin.
Theriogenology.
2012 Jan; 77(2):253-9. doi:
10.1016/j.theriogenology.2011.07.037. [PMID: 21924477] - Govindhaswamy Umapathy, Sadanand D Sontakke, Anuradha Reddy, S Shivaji. Seasonal variations in semen characteristics, semen cryopreservation, estrus synchronization, and successful artificial insemination in the spotted deer (Axis axis).
Theriogenology.
2007 May; 67(8):1371-8. doi:
10.1016/j.theriogenology.2007.01.019. [PMID: 17383719] - K M Morton, S L Catt, W M C Maxwell, G Evans. An efficient method of ovarian stimulation and in vitro embryo production from prepubertal lambs.
Reproduction, fertility, and development.
2005; 17(7):701-6. doi:
10.1071/rd04105. [PMID: 16364223] - A Rastegarnia, A Niasari-Naslaji, P Hovareshti, F Sarhaddi, M Safaei. The effect of different doses of gonadorelin on ovarian follicle dynamics in river buffalo (Bubalus bubalis).
Theriogenology.
2004 Oct; 62(7):1283-91. doi:
10.1016/j.theriogenology.2004.01.014. [PMID: 15325555] - Bradley R Lindsey, Lisa J Maclellan, Timothy R Whyte, James E Kinder, Michael J D'Occhio. Differential requirement for pulsatile LH during the follicular phase and exposure to the preovulatory LH surge for oocyte fertilization and embryo development in cattle.
Theriogenology.
2002 Dec; 58(9):1651-62. doi:
10.1016/s0093-691x(02)01056-7. [PMID: 12472136] - A R Spell, W E Beal, L R Corah, G C Lamb. Evaluating recipient and embryo factors that affect pregnancy rates of embryo transfer in beef cattle.
Theriogenology.
2001 Jul; 56(2):287-97. doi:
10.1016/s0093-691x(01)00563-5. [PMID: 11480620] - L Lopes da Costa, J Chagas e Silva, J Robalo Silva. Superovulatory response, embryo quality and fertility after treatment with different gonadotrophins in native cattle.
Theriogenology.
2001 Jul; 56(1):65-77. doi:
10.1016/s0093-691x(01)00543-x. [PMID: 11467519] - R Browning, F N Schrick, F N Thompson, T Wakefield. Effect of an acute ergotamine challenge on reproductive hormones in follicular phase heifers and progestin-treated cows.
Animal reproduction science.
2001 May; 66(3-4):135-49. doi:
10.1016/s0378-4320(01)00098-7. [PMID: 11348777] - C P Mathis, H E Hawkins, L R Sprott, D K Lunt, D W Forrest. Pregnancy rate in beef heifers after synchronization to either random or programmed estrous cycles.
Journal of animal science.
2001 Mar; 79(3):561-7. doi:
10.2527/2001.793561x. [PMID: 11263814] - S A Hattab, A K Kadoom, R Palme, E Bamberg. Effect of CRESTAR on estrus synchronization and the relationship between fecal and plasma concentrations of progestagens in buffalo cows.
Theriogenology.
2000 Oct; 54(7):1007-17. doi:
10.1016/s0093-691x(00)00409-x. [PMID: 11131319] - M Techakumphu, C Lohachit, W Tantasuparak, C Intaramongkol, S Intaramongkol. Ovarian responses and oocyte recovery in prepubertal swamp buffalo (Bubalus bubalis) calves after FSH or PMSG treatment.
Theriogenology.
2000 Jul; 54(2):305-12. doi:
10.1016/s0093-691x(00)00350-2. [PMID: 11003310] - C Allison Gray, F F Bartol, K M Taylor, A A Wiley, W S Ramsey, T L Ott, F W Bazer, T E Spencer. Ovine uterine gland knock-out model: effects of gland ablation on the estrous cycle.
Biology of reproduction.
2000 Feb; 62(2):448-56. doi:
10.1095/biolreprod62.2.448. [PMID: 10642586] - K M Borchert, C E Farin, S P Washburn. Effect of estrus synchronization with norgestomet on the integrity of oocytes from persistent follicles in beef cattle.
Journal of animal science.
1999 Oct; 77(10):2742-8. doi:
10.2527/1999.77102742x. [PMID: 10521036] - E E van de Leemput, P L Vos, E C Zeinstra, M M Bevers, G C van der Weijden, S J Dieleman. Improved in vitro embryo development using in vivo matured oocytes from heifers superovulated with a controlled preovulatory LH surge.
Theriogenology.
1999 Jul; 52(2):335-49. doi:
10.1016/s0093-691x(99)00133-8. [PMID: 10734399] - M Mihm, N Curran, P Hyttel, P G Knight, M P Boland, J F Roche. Effect of dominant follicle persistence on follicular fluid oestradiol and inhibin and on oocyte maturation in heifers.
Journal of reproduction and fertility.
1999 Jul; 116(2):293-304. doi:
10.1530/jrf.0.1160293. [PMID: 10615254] - D M Beckett, S M Oppenheim, A L Moyer, R H BonDurant, J D Rowe, G B Anderson. Progestin implants can rescue demi-embryo pregnancies in goats: a case study.
Theriogenology.
1999 Jun; 51(8):1505-11. doi:
10.1016/s0093-691x(99)00093-x. [PMID: 10729077] - C A Price, P D Carrière, N Gosselin, H Kohram, L A Guilbault. Effects of superovulation on endogenous LH secretion in cattle, and consequences for embryo production.
Theriogenology.
1999 Jan; 51(1):37-46. doi:
10.1016/s0093-691x(98)00229-5. [PMID: 10729060] - U Singh, N K Khurana, Inderjeet. Plasma progesterone profiles and fertility status of anestrus Zebu cattle treated with norgestomet-estradiol-eCG regimen.
Theriogenology.
1998 Dec; 50(8):1191-9. doi:
10.1016/s0093-691x(98)00219-2. [PMID: 10734434] - B E Cardwell, G Q Fitch, R D Geisert. Ultrasonic evaluation for the time of ovulation in ewes treated with norgestomet and norgestomet followed by pregnant mare's serum gonadotropin.
Journal of animal science.
1998 Sep; 76(9):2235-8. doi:
10.2527/1998.7692235x. [PMID: 9781477] - E E Grings, J B Hall, R A Bellows, R E Short, S E Bellows, R B Staigmiller. Effect of nutritional management, trace mineral supplementation, and norgestomet implant on attainment of puberty in beef heifers.
Journal of animal science.
1998 Aug; 76(8):2177-81. doi:
10.2527/1998.7682177x. [PMID: 9734869] - J Cavalieri, J E Kinder, L A Fitzpatrick. Duration of ovulation suppression with subcutaneous silicone implants containing norgestomet in Bos indicus heifers and cows.
Animal reproduction science.
1998 Apr; 51(1):15-22. doi:
10.1016/s0378-4320(98)00058-x. [PMID: 9672666] - A J Murray, J Cavalieri, M J D'Occhio, T R Whyte, L J Maclellan, L A Fitzpatrick. Treatment with progesterone and 17 beta-oestradiol to induce emergence of a newly-recruited dominant ovulatory follicle during oestrus synchronisation with long-term use of norgestomet in Brahman heifers.
Animal reproduction science.
1998 Feb; 50(1-2):11-26. doi:
10.1016/s0378-4320(97)00082-1. [PMID: 9615176] - B Grimard, P Humblot, J P Mialot, N Jeanguyot, D Sauvant, M Thibier. Absence of response to oestrus induction and synchronization treatment is related to lipid mobilization in suckled beef cows.
Reproduction, nutrition, development.
1997; 37(2):129-40. doi:
10.1051/rnd:19970201. [PMID: 9178354] - G D Smith, H R Sawyer, M A Mirando, M D Griswold, A Sadhu, J J Reeves. Steady-state luteinizing hormone receptor messenger ribonucleic acid levels and endothelial cell composition in bovine normal- and short-lived corpora lutea.
Biology of reproduction.
1996 Oct; 55(4):902-9. doi:
10.1095/biolreprod55.4.902. [PMID: 8879507] - A K Smith, P J Broadbent, D F Dolman, S P Grimmer, D A Davies, H Dobson. Norgestomet implants, plasma progesterone concentrations and embryo transfer pregnancy rates in cattle.
The Veterinary record.
1996 Aug; 139(8):187-91. doi:
10.1136/vr.139.8.187. [PMID: 8873400] - L H Anderson, C M McDowell, M L Day. Progestin-induced puberty and secretion of luteinizing hormone in heifers.
Biology of reproduction.
1996 May; 54(5):1025-31. doi:
10.1095/biolreprod54.5.1025. [PMID: 8722622] - J E Frisch, C J O'Neill. Calving rates in a tropical beef herd after treatment with a synthetic progestagen, norgestomet, or a prostaglandin analogue, cloprostenol.
Australian veterinary journal.
1996 Mar; 73(3):98-102. doi:
10.1111/j.1751-0813.1996.tb09986.x. [PMID: 8660223] - M Legge, B L Hill, G H Shackell, B J McLeod. Glycosaminoglycans of the uterine and vaginal cul-de-sac tissue in the brushtail possum (Trichosurus vulpecula).
Reproduction, fertility, and development.
1996; 8(4):819-23. doi:
10.1071/rd9960819. [PMID: 8870103] - E J Schmitt, M Drost, T Diaz, C Roomes, W W Thatcher. Effect of a gonadotropin-releasing hormone agonist on follicle recruitment and pregnancy rate in cattle.
Journal of animal science.
1996 Jan; 74(1):154-61. doi:
10.2527/1996.741154x. [PMID: 8778094] - M W Smith, J S Stevenson. Fate of the dominant follicle, embryonal survival, and pregnancy rates in dairy cattle treated with prostaglandin F2 alpha and progestins in the absence or presence of a functional corpus luteum.
Journal of animal science.
1995 Dec; 73(12):3743-51. doi:
10.2527/1995.73123743x. [PMID: 8655451] - J Cavalieri, L A Fitzpatrick. Artificial insemination of Bos indicus heifers: the effects of body weight, condition score, ovarian cyclic status and insemination regimen on pregnancy rate.
Australian veterinary journal.
1995 Dec; 72(12):441-7. doi:
10.1111/j.1751-0813.1995.tb03485.x. [PMID: 8825307] - D P Ryan, B Bao, M K Griffith, G L Williams. Metabolic and luteal sequelae to heightened dietary fat intake in undernourished, anestrous beef cows induced to ovulate.
Journal of animal science.
1995 Jul; 73(7):2086-93. doi:
10.2527/1995.7372086x. [PMID: 7592095] - J Cavalieri, L A Fitzpatrick. Oestrus detection techniques and insemination strategies in Bos indicus heifers synchronised with norgestomet-oestradiol.
Australian veterinary journal.
1995 May; 72(5):177-82. doi:
10.1111/j.1751-0813.1995.tb03507.x. [PMID: 7661818] - J S Stevenson, J R Pursley. Resumption of follicular activity and interval to postpartum ovulation after exogenous progestins.
Journal of dairy science.
1994 Mar; 77(3):725-34. doi:
10.3168/jds.s0022-0302(94)77006-5. [PMID: 8169280] - T Sanchez, M E Wehrman, E G Bergfeld, K E Peters, F N Kojima, A S Cupp, V Mariscal, R J Kittok, R J Rasby, J E Kinder. Pregnancy rate is greater when the corpus luteum is present during the period of progestin treatment to synchronize time of estrus in cows and heifers.
Biology of reproduction.
1993 Nov; 49(5):1102-7. doi:
10.1095/biolreprod49.5.1102. [PMID: 8286577] - R J Favero, D B Faulkner, D J Kesler. Norgestomet implants synchronize estrus and enhance fertility in beef heifers subsequent to a timed artificial insemination.
Journal of animal science.
1993 Oct; 71(10):2594-600. doi:
10.2527/1993.71102594x. [PMID: 8226357] - B P Janszen, M M Bevers, M M Ravenshorst, G C van der Weijden, S J Dieleman, M A Taverne. Relationship between prostaglandin-induced luteolysis and temporary inhibition of myometrial activity in late pregnant cows with ear implants containing progestagen.
Journal of reproduction and fertility.
1993 Mar; 97(2):457-61. doi:
10.1530/jrf.0.0970457. [PMID: 8501715] - M M Bevers, S J Dieleman, J T Gielen, Y A Wurth, B P Janszen, J van de Broek, A H Willemse. Yield of embryos in PMSG-superovulated cows treated with anti-PMSG six or 18 hours after the peak of luteinising hormone.
The Veterinary record.
1993 Feb; 132(8):186-9. doi:
10.1136/vr.132.8.186. [PMID: 8451803] - R P Del Vecchio, E E Custer, W E Beal, G S Lewis. Jugular plasma concentrations of 13,14-dihydro-15-keto-prostaglandin F2 alpha in prepubertal beef heifers treated with progestogen then challenged with oxytocin.
Prostaglandins.
1992 Dec; 44(6):509-18. doi:
10.1016/0090-6980(92)90021-k. [PMID: 1475375] - M D Fanning, J C Spitzer, G L Burns, B B Plyler. Luteal function and reproductive response in suckled beef cows after metestrus administration of a norgestomet implant and injection of estradiol valerate with various dosages of injectable norgestomet.
Journal of animal science.
1992 May; 70(5):1352-6. doi:
10.2527/1992.7051352x. [PMID: 1326508] - H A Garverick, M T Moser, D H Keisler, S A Hamilton, R M Roberts, M F Smith. Luteal function after intrauterine infusion of recombinant bovine interferon-alpha I1 into postpartum beef cows expected to have short or normal luteal phases.
Journal of reproduction and fertility.
1992 Mar; 94(2):319-25. doi:
10.1530/jrf.0.0940319. [PMID: 1593534] - K N Bretzlaff, L C Nuti, A D Scarfe, R G Elmore, J Capehart, D D Varner, P G Weston. Luteinizing hormone and progesterone concentrations and induction of estrus after use of norgestomet ear implants or constant infusion of gonadotropin-releasing hormone in anestrous, nonlactating dairy goats.
American journal of veterinary research.
1991 Sep; 52(9):1423-6. doi:
NULL. [PMID: 1952326] - R Rajamahendran, C Taylor. Follicular dynamics and temporal relationships among body temperature, oestrus, the surge of luteinizing hormone and ovulation in Holstein heifers treated with norgestomet.
Journal of reproduction and fertility.
1991 Jul; 92(2):461-7. doi:
10.1530/jrf.0.0920461. [PMID: 1886101] - D A Cooper, D A Carver, P Villeneuve, W J Silvia, E K Inskeep. Effects of progestagen treatment on concentrations of prostaglandins and oxytocin in plasma from the posterior vena cava of post-partum beef cows.
Journal of reproduction and fertility.
1991 Mar; 91(2):411-21. doi:
10.1530/jrf.0.0910411. [PMID: 2013870] - B P Janszen, M M Bevers, S J Dieleman, G C van der Weyden, M A Taverne. Synchronised calvings after withdrawal of norgestomet implants from cows treated near term with prostaglandin.
The Veterinary record.
1990 Oct; 127(16):405-7. doi:
NULL. [PMID: 2267714] - J P Copelin, M F Smith, H A Garverick, R S Youngquist. Effect of termination of pregnancy or long-term progestogen exposure on subsequent estrous cycle length and concentration of progesterone in plasma of heifers.
Journal of animal science.
1989 Jun; 67(6):1552-8. doi:
10.2527/jas1989.6761552x. [PMID: 2768113] - M KayKaty, T L Chang, G Weiss. Determination of the synthetic steroid norgestomet in bovine plasma by capillary column gas chromatography/negative chemical ionization mass spectrometry.
Biomedical & environmental mass spectrometry.
1988 Aug; 17(2):121-6. doi:
10.1002/bms.1200170208. [PMID: 3191250] - J C Mikeska, G L Williams. Timing of preovulatory endocrine events, estrus and ovulation in Brahman x Hereford females synchronized with norgestomet and estradiol valerate.
Journal of animal science.
1988 Apr; 66(4):939-46. doi:
10.2527/jas1988.664939x. [PMID: 2837448] - S L Waller, R E Hudgens, M A Diekman, G E Moss. Effect of melatonin on induction of estrous cycles in anestrous ewes.
Journal of animal science.
1988 Feb; 66(2):459-63. doi:
10.2527/jas1988.662459x. [PMID: 3372387] - L Kostov, G Vasilev, G Elezov, M Dimitrov, S Tsolov. [Methods for synchronizing estrus and selecting recipient heifers in embryo transplantation].
Veterinarno-meditsinski nauki.
1986; 23(4):54-60. doi:
NULL. [PMID: 3016977] - A R Peters. Plasma progesterone and gonadotrophin concentrations following norgestomet treatment with and without cloprostenol in beef cows.
The Veterinary record.
1984 Aug; 115(8):164-6. doi:
10.1136/vr.115.8.164. [PMID: 6435302] - L Ainsworth, M S Wolynetz. Synchronization of estrus and reproductive performance of ewes treated with synthetic progestogens administered by subcutaneous ear implant or by intravaginal sponge pessary.
Journal of animal science.
1982 Jun; 54(6):1120-7. doi:
10.2527/jas1982.5461120x. [PMID: 6179919] - C E Sheffel, B R Pratt, W L Ferrell, E K Inskeep. Induced corpora lutea in the postpartum beef cow. II. Effects of treatment with progestogen and gonadotropins.
Journal of animal science.
1982 Apr; 54(4):830-6. doi:
10.2527/jas1982.544830x. [PMID: 6806234] - G W Kazmer, M A Barnes, R D Halman. Endogenous hormone response and fertility in dairy heifers treated with norgestomet and estradiol valerate.
Journal of animal science.
1981 Nov; 53(5):1333-40. doi:
10.2527/jas1981.5351333x. [PMID: 6798010]