Chitosan oligosaccharide (COS) (BioDeep_00000777971)

   


代谢物信息卡片


beta-D-glucosaminyl-(1->4)-beta-D-glucosamine

化学式: C12H24N2O9 (340.1481734)
中文名称: 壳寡糖
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C1C(C(C(C(O1)OC2C(OC(C(C2O)N)O)CO)N)O)O)O
InChI: InChI=1S/C12H24N2O9/c13-5-9(19)10(4(2-16)21-11(5)20)23-12-6(14)8(18)7(17)3(1-15)22-12/h3-12,15-20H,1-2,13-14H2

描述信息

A beta-D-glucosaminyl-(1->4)-D-glucosamine having beta-configuration at the reducing end anomeric centre.

同义名列表

3 个代谢物同义名

beta-D-glucosaminyl-(1->4)-beta-D-glucosamine; Chitosan oligosaccharide (COS); Chitosan, 2-hydroxypropanoate (ester)



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jiří Simůnek, Ingrid Koppová, Galina Tiščenko, Jan Dohnálek, Jarmila Dušková. Excretome of the chitinolytic bacterium Clostridium paraputrificum J4. Folia microbiologica. 2012 Jul; 57(4):335-9. doi: 10.1007/s12223-012-0137-2. [PMID: 22528309]
  • Mariana Silvia Cretoiu, Anna Maria Kielak, Waleed Abu Al-Soud, Søren J Sørensen, Jan Dirk van Elsas. Mining of unexplored habitats for novel chitinases--chiA as a helper gene proxy in metagenomics. Applied microbiology and biotechnology. 2012 Jun; 94(5):1347-58. doi: 10.1007/s00253-012-4057-5. [PMID: 22526805]
  • Henning S G Beckmann, Heiko M Möller, Valentin Wittmann. High-affinity multivalent wheat germ agglutinin ligands by one-pot click reaction. Beilstein journal of organic chemistry. 2012; 8(?):819-26. doi: 10.3762/bjoc.8.91. [PMID: 23015829]
  • Pallinti Purushotham, P V Parvati Sai Arun, Jogadhenu S S Prakash, Appa Rao Podile. Chitin binding proteins act synergistically with chitinases in Serratia proteamaculans 568. PloS one. 2012; 7(5):e36714. doi: 10.1371/journal.pone.0036714. [PMID: 22590591]
  • M Rabeeth, A Anitha, Geetha Srikanth. Purification of an antifungal endochitinase from a potential biocontrol Agent Streptomyces griseus. Pakistan journal of biological sciences : PJBS. 2011 Aug; 14(16):788-97. doi: 10.3923/pjbs.2011.788.797. [PMID: 22545353]
  • Florian Rieder, Rocio Lopez, Andre Franke, Alexandra Wolf, Stephan Schleder, Andrea Dirmeier, Anja Schirbel, Philip Rosenstiel, Nir Dotan, Stefan Schreiber, Gerhard Rogler, Frank Klebl. Characterization of changes in serum anti-glycan antibodies in Crohn's disease--a longitudinal analysis. PloS one. 2011 May; 6(5):e18172. doi: 10.1371/journal.pone.0018172. [PMID: 21573154]
  • Akkaladevi Narahari, Hitesh Singla, Pavan Kumar Nareddy, Gopalakrishnan Bulusu, Avadhesha Surolia, Musti J Swamy. Isothermal titration calorimetric and computational studies on the binding of chitooligosaccharides to pumpkin (Cucurbita maxima) phloem exudate lectin. The journal of physical chemistry. B. 2011 Apr; 115(14):4110-7. doi: 10.1021/jp110468n. [PMID: 21405077]
  • Yoshinobu Kimura, Yuki Takeoka, Masami Inoue, Megumi Maeda, Kazuhito Fujiyama. Double-knockout of putative endo-β-N-acetylglucosaminidase (ENGase) genes in Arabidopsis thaliana: loss of ENGase activity induced accumulation of high-mannose type free N-glycans bearing N,N'-acetylchitobiosyl unit. Bioscience, biotechnology, and biochemistry. 2011; 75(5):1019-21. doi: 10.1271/bbb.110148. [PMID: 21597164]
  • Ryan G Rhodes, Janet A Atoyan, David R Nelson. The chitobiose transporter, chbC, is required for chitin utilization in Borrelia burgdorferi. BMC microbiology. 2010 Jan; 10(?):21. doi: 10.1186/1471-2180-10-21. [PMID: 20102636]
  • Yong Zhao, Ro-Dong Park, Riccardo A A Muzzarelli. Chitin deacetylases: properties and applications. Marine drugs. 2010 Jan; 8(1):24-46. doi: 10.3390/md8010024. [PMID: 20161969]
  • Anne Dell, Alaa Galadari, Federico Sastre, Paul Hitchen. Similarities and differences in the glycosylation mechanisms in prokaryotes and eukaryotes. International journal of microbiology. 2010; 2010(?):148178. doi: 10.1155/2010/148178. [PMID: 21490701]
  • Donovan P German, Rosalie A Bittong. Digestive enzyme activities and gastrointestinal fermentation in wood-eating catfishes. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. 2009 Nov; 179(8):1025-42. doi: 10.1007/s00360-009-0383-z. [PMID: 19568757]
  • Maria Allhorn, Anders I Olin, Falk Nimmerjahn, Mattias Collin. Human IgG/Fc gamma R interactions are modulated by streptococcal IgG glycan hydrolysis. PloS one. 2008 Jan; 3(1):e1413. doi: 10.1371/journal.pone.0001413. [PMID: 18183294]
  • Kathleen Marchal, Sigrid C J De Keersmaecker. Bacterial networking. Genome biology. 2008; 9(11):327. doi: 10.1186/gb-2008-9-11-327. [PMID: 19014672]
  • Andreas Marquardt, Bogdan Bernevic, Michael Przybylski. Identification, affinity characterisation and biological interactions of lectin-like peptide-carbohydrate complexes derived from human TNF-alpha using high-resolution mass spectrometry. Journal of peptide science : an official publication of the European Peptide Society. 2007 Dec; 13(12):803-10. doi: 10.1002/psc.902. [PMID: 17918767]
  • Harumi Yamamoto, Hiromu Takematsu, Reiko Fujinawa, Yuko Naito, Yasushi Okuno, Gozoh Tsujimoto, Akemi Suzuki, Yasunori Kozutsumi. Correlation index-based responsible-enzyme gene screening (CIRES), a novel DNA microarray-based method for enzyme gene involved in glycan biosynthesis. PloS one. 2007 Nov; 2(11):e1232. doi: 10.1371/journal.pone.0001232. [PMID: 18043739]
  • Zhongli Cui, Yukie Maruyama, Bunzo Mikami, Wataru Hashimoto, Kousaku Murata. Crystal structure of glycoside hydrolase family 78 alpha-L-Rhamnosidase from Bacillus sp. GL1. Journal of molecular biology. 2007 Nov; 374(2):384-98. doi: 10.1016/j.jmb.2007.09.003. [PMID: 17936784]
  • R Müller, M Marchetti, M Kratzmeier, H Elgass, M Kuschel, A Zenker, G Allmaier. Comparison of planar SDS-PAGE, CGE-on-a-chip, and MALDI-TOF mass spectrometry for analysis of the enzymatic de-N-glycosylation of antithrombin III and coagulation factor IX with PNGase F. Analytical and bioanalytical chemistry. 2007 Nov; 389(6):1859-68. doi: 10.1007/s00216-007-1586-3. [PMID: 17879089]
  • S N Pramod, Y P Venkatesh, P A Mahesh. Potato lectin activates basophils and mast cells of atopic subjects by its interaction with core chitobiose of cell-bound non-specific immunoglobulin E. Clinical and experimental immunology. 2007 Jun; 148(3):391-401. doi: 10.1111/j.1365-2249.2007.03368.x. [PMID: 17362264]
  • Julie Bouckaert, Jenny Mackenzie, José L de Paz, Beatrice Chipwaza, Devapriya Choudhury, Anton Zavialov, Karin Mannerstedt, Jennifer Anderson, Denis Piérard, Lode Wyns, Peter H Seeberger, Stefan Oscarson, Henri De Greve, Stefan D Knight. The affinity of the FimH fimbrial adhesin is receptor-driven and quasi-independent of Escherichia coli pathotypes. Molecular microbiology. 2006 Sep; 61(6):1556-68. doi: 10.1111/j.1365-2958.2006.05352.x. [PMID: 16930149]
  • Suguru Oguri. Analysis of sugar chain-binding specificity of tomato lectin using lectin blot: recognition of high mannose-type N-glycans produced by plants and yeast. Glycoconjugate journal. 2005 Nov; 22(7-9):453-61. doi: 10.1007/s10719-005-5329-4. [PMID: 16311890]
  • An-Shu Chen, Tadao Taguchi, Kazuo Sakai, Yoshiharu Matahira, Min-Wei Wang, Ichitomo Miwa. Effect of chitobiose and chitotriose on carbon tetrachloride-induced acute hepatotoxicity in rats. Biological & pharmaceutical bulletin. 2005 Oct; 28(10):1971-3. doi: 10.1248/bpb.28.1971. [PMID: 16204957]
  • Chun Tang, Junji Iwahara, G Marius Clore. Accurate determination of leucine and valine side-chain conformations using U-[15N/13C/2H]/[1H-(methine/methyl)-Leu/Val] isotope labeling, NOE pattern recognition, and methine Cgamma-Hgamma/Cbeta-Hbeta residual dipolar couplings: application to the 34-kDa enzyme IIA(chitobiose). Journal of biomolecular NMR. 2005 Oct; 33(2):105-21. doi: 10.1007/s10858-005-1206-5. [PMID: 16258829]
  • An-Shu Chen, Tadao Taguchi, Hirokazu Okamoto, Kazumi Danjo, Kazuo Sakai, Yoshiharu Matahira, Min-Wei Wang, Ichitomo Miwa. Pharmacokinetics of chitobiose and chitotriose administered intravenously or orally to rats. Biological & pharmaceutical bulletin. 2005 Mar; 28(3):545-8. doi: 10.1248/bpb.28.545. [PMID: 15744088]
  • Chien-Jui Huang, Chao-Ying Chen. High-level expression and characterization of two chitinases, ChiCH and ChiCW, of Bacillus cereus 28-9 in Escherichia coli. Biochemical and biophysical research communications. 2005 Feb; 327(1):8-17. doi: 10.1016/j.bbrc.2004.11.140. [PMID: 15629422]
  • Cédric F V Hobel, Gudmundur O Hreggvidsson, Viggó T Marteinsson, Farah Bahrani-Mougeot, Jón M Einarsson, Jakob K Kristjánsson. Cloning, expression, and characterization of a highly thermostable family 18 chitinase from Rhodothermus marinus. Extremophiles : life under extreme conditions. 2005 Feb; 9(1):53-64. doi: 10.1007/s00792-004-0422-3. [PMID: 15583965]
  • Kazuki Nakajima, Mitsuhiro Kinoshita, Yasuo Oda, Takashi Masuko, Hanae Kaku, Naoto Shibuya, Kazuaki Kakehi. Screening method of carbohydrate-binding proteins in biological sources by capillary affinity electrophoresis and its application to determination of Tulipa gesneriana agglutinin in tulip bulbs. Glycobiology. 2004 Sep; 14(9):793-804. doi: 10.1093/glycob/cwh094. [PMID: 15148295]
  • Nuria Aboitiz, F Javier Cañada, Lucie Husakova, Marek Kuzma, Vladimír Kren, Jesús Jiménez-Barbero. Enzymatic synthesis of complex glycosaminotrioses and study of their molecular recognition by hevein domains. Organic & biomolecular chemistry. 2004 Jul; 2(14):1987-94. doi: 10.1039/b401037j. [PMID: 15254625]
  • A Saito, H Schrempf. Mutational analysis of the binding affinity and transport activity for N-acetylglucosamine of the novel ABC transporter Ngc in the chitin-degrader Streptomyces olivaceoviridis. Molecular genetics and genomics : MGG. 2004 Jun; 271(5):545-53. doi: 10.1007/s00438-004-0981-0. [PMID: 15148605]
  • Bruno G G Donzelli, Gary Ostroff, Gary E Harman. Enhanced enzymatic hydrolysis of langostino shell chitin with mixtures of enzymes from bacterial and fungal sources. Carbohydrate research. 2003 Sep; 338(18):1823-33. doi: 10.1016/s0008-6215(03)00269-6. [PMID: 12932365]
  • A Plá, E Alonso, F Batista-Viera, L Franco Fraguas. Screening for carbohydrate-binding proteins in extracts of Uruguayan plants. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 2003 Jul; 36(7):851-60. doi: 10.1590/s0100-879x2003000700005. [PMID: 12845371]
  • E V Chandrasekaran, Ram Chawda, John M Rhodes, Robert D Locke, Conrad F Piskorz, Khushi L Matta. The binding characteristics and utilization of Aleuria aurantia, Lens culinaris and few other lectins in the elucidation of fucosyltransferase activities resembling cloned FT VI and apparently unique to colon cancer cells. Carbohydrate research. 2003 Apr; 338(9):887-901. doi: 10.1016/s0008-6215(03)00021-1. [PMID: 12681913]
  • X Xiao, F Wang, A Saito, J Majka, A Schlösser, H Schrempf. The novel Streptomyces olivaceoviridis ABC transporter Ngc mediates uptake of N-acetylglucosamine and N,N'-diacetylchitobiose. Molecular genetics and genomics : MGG. 2002 Jun; 267(4):429-39. doi: 10.1007/s00438-002-0640-2. [PMID: 12111550]
  • R B Day, M Okada, Y Ito, K Tsukada, H Zaghouani, N Shibuya, G Stacey. Binding site for chitin oligosaccharides in the soybean plasma membrane. Plant physiology. 2001 Jul; 126(3):1162-73. doi: 10.1104/pp.126.3.1162. [PMID: 11457966]
  • M Collin, A Olsén. EndoS, a novel secreted protein from Streptococcus pyogenes with endoglycosidase activity on human IgG. The EMBO journal. 2001 Jun; 20(12):3046-55. doi: 10.1093/emboj/20.12.3046. [PMID: 11406581]