potassium cyanide (BioDeep_00000777616)

   


代谢物信息卡片


potassium cyanide

  化学式: CKN (64.9668)
中文名称: 氰化钾
  谱图信息: 最多检出来源 () %

分子结构信息

SMILES: [C-]#N.[K+]
InChI: InChI=1S/CN.K/c1-2

描述信息

D009676 - Noxae > D011042 - Poisons
D004791 - Enzyme Inhibitors

同义名列表

1 个代谢物同义名

potassium cyanide



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome()

BioCyc(29)

PlantCyc(11)

代谢反应

个相关的代谢反应过程信息。

Reactome()

BioCyc()

WikiPathways()

Plant Reactome()

INOH()

PlantCyc()

COVID-19 Disease Map()

PathBank()

PharmGKB()

个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Omotayo B Ilesanmi, Afolabi C Akinmoladun, Christianah A Elusiyan, Ifedayo V Ogungbe, Tiwalade A Olugbade, M Tolulope Olaleye. Neuroprotective flavonoids of the leaf of Antiaris africana Englea against cyanide toxicity. Journal of ethnopharmacology. 2022 Jan; 282(?):114592. doi: 10.1016/j.jep.2021.114592. [PMID: 34480996]
  • Steven Dang, Albert K Tsui, Richard Herndon, Cheryl Babiak, Artur Szkotak, Anna K Füzéry, Joshua E Raizman. Hydroxocobalamin interference in routine laboratory tests: Development of a protocol for identifying samples and reporting results from patients treated with CyanokitTM. Clinical biochemistry. 2021 May; 91(?):31-38. doi: 10.1016/j.clinbiochem.2021.01.001. [PMID: 33444605]
  • Michael Kurz, Dirk Gretzke, Rolf Hörlein, Sandrine Turpault, Jens Atzrodt, Volker Derdau. Carbon-13 synthesis and NMR spectroscopic geometric isomer evaluation to support the filing of teriflunomide. Journal of labelled compounds & radiopharmaceuticals. 2021 02; 64(2):82-88. doi: 10.1002/jlcr.3876. [PMID: 32840004]
  • Seán M Kilbride, Jayne E Telford, Gavin P Davey. Complex I Controls Mitochondrial and Plasma Membrane Potentials in Nerve Terminals. Neurochemical research. 2021 Jan; 46(1):100-107. doi: 10.1007/s11064-020-02990-8. [PMID: 32130629]
  • Rolf Kinne, Katherine C Spokes, Patricio Silva. Sugar uptake, metabolism, and chloride secretion in the rectal gland of the spiny dogfish Squalus acanthias. American journal of physiology. Regulatory, integrative and comparative physiology. 2020 07; 319(1):R96-R105. doi: 10.1152/ajpregu.00060.2020. [PMID: 32459971]
  • Elizabeth Harmon, Jacob Lebin, David Murphy, Bjorn Watsjold. Fatality from potassium gold cyanide poisoning. BMJ case reports. 2019 Jul; 12(7):. doi: 10.1136/bcr-2019-229947. [PMID: 31350229]
  • Muhammad Avais, Muhammad Sarwar Khan, Muhammad Arif Khan, Kamran Ashraf, Zahoorul Hassan, Sajid Hameed, Jawaria Ali Khan. Histopathological changes induced in liver, kidney, heart and pancreas of rabbits by prolonged oral cyanide exposure. Pakistan journal of pharmaceutical sciences. 2018 Sep; 31(5):1797-1803. doi: NULL. [PMID: 30150173]
  • Gabriella Roda, Sebastiano Arnoldi, Michele Dei Cas, Valeria Ottaviano, Eleonora Casagni, Fausto Tregambe, Giacomo Luca Visconti, Fiorenza Farè, Rino Froldi, Veniero Gambaro. Determination of Cyanide by Microdiffusion Technique Coupled to Spectrophotometry and GC/NPD and Propofol by Fast GC/MS-TOF in a Case of Poisoning. Journal of analytical toxicology. 2018 Jul; 42(6):e51-e57. doi: 10.1093/jat/bky015. [PMID: 30007331]
  • Nazar Abdulameer Hamzah, Eman Salman Raheif. Purification and properties of Manganese Superoxide Dismutase (MnSOD) from Tamarix aphylla L. Cellular and molecular biology (Noisy-le-Grand, France). 2018 May; 64(7):19-23. doi: . [PMID: 29974841]
  • Gábor Bernát, Gábor Steinbach, Radek Kaňa, Govindjee, Amarendra N Misra, Ondřej Prašil. On the origin of the slow M-T chlorophyll a fluorescence decline in cyanobacteria: interplay of short-term light-responses. Photosynthesis research. 2018 May; 136(2):183-198. doi: 10.1007/s11120-017-0458-8. [PMID: 29090427]
  • Muhammad Avais, Muhammad Sarwar Khan, Muhammad Arif Khan, Kamran Ashraf, Zahoorul Hassan, Jawaria Ali Khan, Nisar Ahmad. Assessing the efficacy of aqueous garlic extract, sodium nitrite and sodium thiosulfate against prolonged oral cyanide exposure in rabbits. Pakistan journal of pharmaceutical sciences. 2018 Mar; 31(2):411-419. doi: ". [PMID: 29618429]
  • Anica M Petkovic, Vladimir Lj Jakovljevic, Jovana V Bradic, Jovana N Jeremic, Nevena S Jeremic, Tamara R Nikolic Turnic, Nemanja U Jovicic, Vesna Z Rosic, Ivan M Srejovic, Vladimir I Zivkovic. The Effects of Potassium Cyanide on the Functional Recovery of Isolated Rat Hearts after Ischemia and Reperfusion: The Role of Oxidative Stress. Oxidative medicine and cellular longevity. 2018; 2018(?):5979721. doi: 10.1155/2018/5979721. [PMID: 30116485]
  • L S Khailova, T I Rokitskaya, E A Kotova, Y N Antonenko. Effect of Cyanide on Mitochondrial Membrane Depolarization Induced by Uncouplers. Biochemistry. Biokhimiia. 2017 Oct; 82(10):1140-1146. doi: 10.1134/s0006297917100066. [PMID: 29037134]
  • Biswaranjan Paital, Gaurav Sablok, Sunil Kumar, Sanjeev Kumar Singh, G B N Chainy. Investigating the Conformational Structure and Potential Site Interactions of SOD Inhibitors on Ec-SOD in Marine Mud Crab Scylla serrata: A Molecular Modeling Approach. Interdisciplinary sciences, computational life sciences. 2016 Sep; 8(3):312-8. doi: 10.1007/s12539-015-0110-2. [PMID: 26286009]
  • Patrick J Sabourin, Christina L Kobs, Seth T Gibbs, Peter Hong, Claire M Matthews, Kristen M Patton, Carol L Sabourin, Edgar J Wakayama. Characterization of a Mouse Model of Oral Potassium Cyanide Intoxication. International journal of toxicology. 2016 09; 35(5):584-603. doi: 10.1177/1091581816646973. [PMID: 27170682]
  • Sergey Zakharov, Manuela Vaneckova, Zdenek Seidl, Pavel Diblik, Pavel Kuthan, Pavel Urban, Tomas Navratil, Daniela Pelclova. Successful Use of Hydroxocobalamin and Sodium Thiosulfate in Acute Cyanide Poisoning: A Case Report with Follow-up. Basic & clinical pharmacology & toxicology. 2015 Sep; 117(3):209-12. doi: 10.1111/bcpt.12387. [PMID: 25645744]
  • Yang-Wen-Ke Liao, Ya-Ru Liu, Jia-Yang Liang, Wen-Ping Wang, Jie Zhou, Xiao-Jian Xia, Yan-Hong Zhou, Jing-Quan Yu, Kai Shi. The relationship between the plant-encoded RNA-dependent RNA polymerase 1 and alternative oxidase in tomato basal defense against Tobacco mosaic virus. Planta. 2015 Mar; 241(3):641-50. doi: 10.1007/s00425-014-2207-y. [PMID: 25408506]
  • Anna Bilska-Wilkosz, Magdalena Dudek, Joanna Knutelska, Lidia Włodek. The effect of lipoic acid administration on the urinary excretion of thiocyanate in rats exposed to potassium cyanide. Acta poloniae pharmaceutica. 2015 Jan; 72(1):49-52. doi: NULL. [PMID: 25850200]
  • Natalia Tsesin, Boris Khalfin, Ilana Nathan, Abraham H Parola. Cardiolipin plays a role in KCN-induced necrosis. Chemistry and physics of lipids. 2014 Oct; 183(?):159-68. doi: 10.1016/j.chemphyslip.2014.06.007. [PMID: 24995676]
  • Caleb M Rounds, Peter K Hepler, Lawrence J Winship. The apical actin fringe contributes to localized cell wall deposition and polarized growth in the lily pollen tube. Plant physiology. 2014 Sep; 166(1):139-51. doi: 10.1104/pp.114.242974. [PMID: 25037212]
  • Ross Hill, Milán Szabó, Ateeq ur Rehman, Imre Vass, Peter J Ralph, Anthony W D Larkum. Inhibition of photosynthetic CO₂ fixation in the coral Pocillopora damicornis and its relationship to thermal bleaching. The Journal of experimental biology. 2014 Jun; 217(Pt 12):2150-62. doi: 10.1242/jeb.100578. [PMID: 24675559]
  • T Yamagiwa, A T Kawaguchi, T Saito, S Inoue, S Morita, K Watanabe, H Kitagishi, K Koji, S Inokuchi. Supramolecular ferric porphyrins and a cyclodextrin dimer as antidotes for cyanide poisoning. Human & experimental toxicology. 2014 Apr; 33(4):360-8. doi: 10.1177/0960327113499041. [PMID: 23918903]
  • Altamir Benedito de Sousa, Silvana Lima Górniak. Toxicokinetic aspects of thiocyanate after oral exposure to cyanide in female Wistar rats in different physiological states. Drug and chemical toxicology. 2014 Jan; 37(1):63-8. doi: 10.3109/01480545.2013.806533. [PMID: 23841473]
  • Ahmed E Abdel Moneim. Citrus peel extract attenuates acute cyanide poisoning-induced seizures and oxidative stress in rats. CNS & neurological disorders drug targets. 2014; 13(4):638-46. doi: 10.2174/1871527312666131206095142. [PMID: 24308563]
  • Poonam Singh, Pooja Rao, Rahul Bhattacharya. Dose and time-dependent effects of cyanide on thiosulfate sulfurtransferase, 3-mercaptopyruvate sulfurtransferase, and cystathionine λ-lyase activities. Journal of biochemical and molecular toxicology. 2013 Dec; 27(12):499-507. doi: 10.1002/jbt.21514. [PMID: 23929717]
  • Brendan L Mitchell, Raj K Bhandari, Vikhyat S Bebarta, Gary A Rockwood, Gerry R Boss, Brian A Logue. Toxicokinetic profiles of α-ketoglutarate cyanohydrin, a cyanide detoxification product, following exposure to potassium cyanide. Toxicology letters. 2013 Sep; 222(1):83-9. doi: 10.1016/j.toxlet.2013.07.008. [PMID: 23867915]
  • Jerónimo Guzmán-Deara, Homero Reyes-De la Cruz, Elda María Beltrán-Peña, Elda Castro-Mercado, Ernesto García-Pineda. Identification and characterization of superoxide dismutase in Phytophthora cinnamomi. Protoplasma. 2013 Jun; 250(3):779-85. doi: 10.1007/s00709-012-0464-9. [PMID: 23086260]
  • E V Pradedova, I S Trukhan, O D Nimaeva, R K Salyaev. Hydrogen peroxide generation in the vacuoles of red beet root cells. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. 2013 Mar; 449(?):106-9. doi: 10.1134/s0012496613020129. [PMID: 23652440]
  • Fei Xu, Da-Wei Zhang, Feng Zhu, He Tang, Xin Lv, Jian Cheng, Huang-Fan Xie, Hong-Hui Lin. A novel role for cyanide in the control of cucumber (Cucumis sativus L.) seedlings response to environmental stress. Plant, cell & environment. 2012 Nov; 35(11):1983-97. doi: 10.1111/j.1365-3040.2012.02531.x. [PMID: 22554042]
  • Harvey A Schwertner, Sandra Valtier, Vikhyat S Bebarta. Liquid chromatographic mass spectrometric (LC/MS/MS) determination of plasma hydroxocobalamin and cyanocobalamin concentrations after hydroxocobalamin antidote treatment for cyanide poisoning. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 Sep; 905(?):10-6. doi: 10.1016/j.jchromb.2012.07.012. [PMID: 22939270]
  • Xiao-Zhang Yu, Fu-Zhong Zhang. Activities of nitrate reductase and glutamine synthetase in rice seedlings during cyanide metabolism. Journal of hazardous materials. 2012 Jul; 225-226(?):190-4. doi: 10.1016/j.jhazmat.2012.05.027. [PMID: 22633925]
  • Xiao-Zhang Yu, Peng-Cheng Lu, Zhen Yu. On the role of β-cyanoalanine synthase (CAS) in metabolism of free cyanide and ferri-cyanide by rice seedlings. Ecotoxicology (London, England). 2012 Mar; 21(2):548-56. doi: 10.1007/s10646-011-0815-x. [PMID: 22068263]
  • Yang-Wen-Ke Liao, Kai Shi, Li-Jun Fu, Shuai Zhang, Xin Li, De-Kun Dong, Yu-Ping Jiang, Yan-Hong Zhou, Xiao-Jian Xia, Wu-Sheng Liang, Jing-Quan Yu. The reduction of reactive oxygen species formation by mitochondrial alternative respiration in tomato basal defense against TMV infection. Planta. 2012 Feb; 235(2):225-38. doi: 10.1007/s00425-011-1483-z. [PMID: 21779957]
  • Ruth Chang, Charles J H Jang, Cristina Branco-Price, Peter Nghiem, Julia Bailey-Serres. Transient MPK6 activation in response to oxygen deprivation and reoxygenation is mediated by mitochondria and aids seedling survival in Arabidopsis. Plant molecular biology. 2012 Jan; 78(1-2):109-22. doi: 10.1007/s11103-011-9850-5. [PMID: 22086331]
  • N Eskandarzade, M Aminlari, S Golami, M Tavana. Rhodanese activity in different tissues of the ostrich. British poultry science. 2012; 53(2):270-3. doi: 10.1080/00071668.2012.682722. [PMID: 22646793]
  • O M Bolaji, O O Olabode. Modulating effect of aqueous extract of Telfairia occidentalis on induced cyanide toxicity in rats. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. 2011 Dec; 26(2):185-91. doi: . [PMID: 22547189]
  • Ling-Hsuan Kung, Karie E Scrogin. Serotonin nerve terminals in the dorsomedial medulla facilitate sympathetic and ventilatory responses to hemorrhage and peripheral chemoreflex activation. American journal of physiology. Regulatory, integrative and comparative physiology. 2011 Nov; 301(5):R1367-79. doi: 10.1152/ajpregu.00576.2010. [PMID: 21813868]
  • Kevin A Ford, Alexander G Gulevich, Tami L Swenson, John E Casida. Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition. Journal of agricultural and food chemistry. 2011 May; 59(9):4860-7. doi: 10.1021/jf200485k. [PMID: 21476569]
  • I Yu Subota, A Sh Arziev, G A Nevinsky, Yu M Konstantinov. Effect of redox conditions on the synthesis and phosphorylation of β-subunit of mitochondrial F(0)F (1)-ATPase of maize (Zea mays). Doklady. Biochemistry and biophysics. 2011 May; 438(?):144-6. doi: 10.1134/s1607672911030100. [PMID: 21725894]
  • Vicente P Martins, Taisa M Dinamarco, Frederico M Soriani, Valéria G Tudella, Sergio C Oliveira, Gustavo H Goldman, Carlos Curti, Sérgio A Uyemura. Involvement of an alternative oxidase in oxidative stress and mycelium-to-yeast differentiation in Paracoccidioides brasiliensis. Eukaryotic cell. 2011 Feb; 10(2):237-48. doi: 10.1128/ec.00194-10. [PMID: 21183691]
  • Ahmed O Abdel-Zaher, Randa H Abdel-Hady, Wafaa M Abdel Moneim, Safa Y Salim. Alpha-lipoic acid protects against potassium cyanide-induced seizures and mortality. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 2011 Jan; 63(1-2):161-5. doi: 10.1016/j.etp.2009.11.004. [PMID: 19962284]
  • Hiroshi Nishi, Reiko Inagi, Norifumi Kawada, Katsutoshi Yoshizato, Imari Mimura, Toshiro Fujita, Masaomi Nangaku. Cytoglobin, a novel member of the globin family, protects kidney fibroblasts against oxidative stress under ischemic conditions. The American journal of pathology. 2011 Jan; 178(1):128-39. doi: 10.1016/j.ajpath.2010.11.011. [PMID: 21224051]
  • Yu-Chen Miao, Chang-Jun Liu. ATP-binding cassette-like transporters are involved in the transport of lignin precursors across plasma and vacuolar membranes. Proceedings of the National Academy of Sciences of the United States of America. 2010 Dec; 107(52):22728-33. doi: 10.1073/pnas.1007747108. [PMID: 21149736]
  • Congli Wang, Steven Lower, Varghese P Thomas, Valerie M Williamson. Root-knot nematodes exhibit strain-specific clumping behavior that is inherited as a simple genetic trait. PloS one. 2010 Dec; 5(12):e15148. doi: 10.1371/journal.pone.0015148. [PMID: 21151553]
  • K L Hon, K L Cheung. Pink toes and red urine: what is this poison?. Hong Kong medical journal = Xianggang yi xue za zhi. 2010 Oct; 16(5):411-2. doi: NULL. [PMID: 20890011]
  • S Sajitha Rajan, K Murugan. Purification and kinetic characterization of the liverwort Pallavicinia lyelli (Hook.) S. Gray. cytosolic ascorbate peroxidase. Plant physiology and biochemistry : PPB. 2010 Sep; 48(9):758-63. doi: 10.1016/j.plaphy.2010.06.004. [PMID: 20619666]
  • Kei Kimura, Hidekazu Kuwayama, Aiko Amagai, Yasuo Maeda. Developmental significance of cyanide-resistant respiration under stressed conditions: experiments in Dictyostelium cells. Development, growth & differentiation. 2010 Sep; 52(7):645-56. doi: 10.1111/j.1440-169x.2010.01200.x. [PMID: 20887565]
  • Barnabás Wodala, Attila Ordög, Ferenc Horváth. The cost and risk of using sodium nitroprusside as a NO donor in chlorophyll fluorescence experiments. Journal of plant physiology. 2010 Sep; 167(13):1109-11. doi: 10.1016/j.jplph.2010.03.013. [PMID: 20462656]
  • R M Satpute, J Hariharakrishnan, R Bhattacharya. Effect of alpha-ketoglutarate and N-acetyl cysteine on cyanide-induced oxidative stress mediated cell death in PC12 cells. Toxicology and industrial health. 2010 Jun; 26(5):297-308. doi: 10.1177/0748233710365695. [PMID: 20356861]
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  • L A Vasil'ev, A A Vorobyov, E V Dzyubinskaya, A V Nesov, A A Shestak, V D Samuilov. Cyanide-induced death of cells in plant leaves. Biochemistry. Biokhimiia. 2007 May; 72(5):572-82. doi: 10.1134/s000629790705015x. [PMID: 17573713]
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