Chrysosplenol (BioDeep_00000007761)

 

Secondary id: BioDeep_00000270026

human metabolite PANOMIX_OTCML-2023 Volatile Flavor Compounds natural product


代谢物信息卡片


5,6-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7-dimethoxy-4H-chromen-4-one

化学式: C18H16O8 (360.0845136)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 2.8%

分子结构信息

SMILES: C1(OC)=CC2OC(C3C=CC(O)=C(OC)C=3)=C(OC)C(=O)C=2C(O)=C1O
InChI: InChI=1S/C18H16O8/c1-23-10-6-8(4-5-9(10)19)17-18(25-3)16(22)13-11(26-17)7-12(24-2)14(20)15(13)21/h4-7,19-21H,1-3H3

描述信息

Chrysosplenol, also known as quercetagetin 3,7,3-trimethyl ether or 4,5,6-trihydroxy-3,3,7-trimethoxyflavone, is a member of the class of compounds known as 7-o-methylated flavonoids. 7-o-methylated flavonoids are flavonoids with methoxy groups attached to the C7 atom of the flavonoid backbone. Thus, chrysosplenol is considered to be a flavonoid lipid molecule. Chrysosplenol is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Chrysosplenol can be found in german camomile, which makes chrysosplenol a potential biomarker for the consumption of this food product.

同义名列表

6 个代谢物同义名

5,6-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7-dimethoxy-4H-chromen-4-one; 4,5,6-Trihydroxy-3,3,7-trimethoxyflavone; Quercetagetin 3,7,3-trimethyl ether; Chrysosplenol C; Chrysosplenol; Chrysosplenol C



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(2)

代谢反应

4 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(2)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

42 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Tanja Hell, Adriano Rutz, Lara Dürr, Maciej Dobrzyński, Jakob K Reinhardt, Timo Lehner, Morris Keller, Anika John, Mahabir Gupta, Olivier Pertz, Matthias Hamburger, Jean-Luc Wolfender, Eliane Garo. Combining Activity Profiling with Advanced Annotation to Accelerate the Discovery of Natural Products Targeting Oncogenic Signaling in Melanoma. Journal of natural products. 2022 06; 85(6):1540-1554. doi: 10.1021/acs.jnatprod.2c00146. [PMID: 35640148]
  • Nguyen Phuong Thao, Bui Thi Thuy Luyen, Bui Huu Tai, Nguyen Manh Cuong, Youn Chul Kim, Chau Van Minh, Young Ho Kim. Chemical constituents of Miliusa balansae leaves and inhibition of nitric oxide production in lipopolysaccharide-induced RAW 264.7 cells. Bioorganic & medicinal chemistry letters. 2015 Sep; 25(18):3859-63. doi: 10.1016/j.bmcl.2015.07.056. [PMID: 26238320]
  • Min-Jeong Son, Hyun Kyung Kim, Do Thi Thu Huong, Young Ho Kim, Tran Van Sung, Nguyen Manh Cuong, Sun-Hee Woo. Chrysosplenol C increases contraction in rat ventricular myocytes. Journal of cardiovascular pharmacology. 2011 Feb; 57(2):259-62. doi: 10.1097/fjc.0b013e318201f119. [PMID: 21052017]
  • S J Semple, S F Nobbs, S M Pyke, G D Reynolds, R L Flower. Antiviral flavonoid from Pterocaulon sphacelatum, an Australian Aboriginal medicine. Journal of ethnopharmacology. 1999 Dec; 68(1-3):283-8. doi: 10.1016/s0378-8741(99)00050-1. [PMID: 10624889]