Dihydroetorphine (BioDeep_00000773369)
Main id: BioDeep_00000178300
代谢物信息卡片
化学式: C25H35NO4 (413.25659500000006)
中文名称: 二氢埃托啡
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCC(C)(C1CC23CCC1(C4C25CCN(C3CC6=C5C(=C(C=C6)O)O4)C)OC)O
InChI: InChI=1S/C25H35NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,17-18,21,27-28H,5,8-14H2,1-4H3/t17-,18-,21-,22-,23-,24+,25-/m1/s1
描述信息
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics
D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Erik Olofsen, Merel Boom, Elise Sarton, Monique van Velzen, Paul Baily, Kevin J Smith, Alexander Oksche, Albert Dahan, Marieke Niesters. Analgesic and Respiratory Depressant Effects of R-dihydroetorphine: A Pharmacokinetic-Pharmacodynamic Analysis in Healthy Male Volunteers.
Anesthesiology.
2019 12; 131(6):1327-1339. doi:
10.1097/aln.0000000000002991
. [PMID: 31651529] - S Ohmori, L Fang, M Kawase, S Saito, Y Morimoto. Tolerance to analgesia and dependence liability by topical application of dihydroetorphine to hairless rats.
European journal of pharmacology.
2001 Jul; 423(2-3):157-66. doi:
10.1016/s0014-2999(01)01098-6
. [PMID: 11448480] - S Ohmori, T Hayashi, M Kawase, S Saito, Y Morimoto. Pharmacokinetic and pharmacodynamic evaluations of a potent analgesic, dihydroetorphine, in hairless rat.
The Journal of pharmacology and experimental therapeutics.
2001 Feb; 296(2):528-36. doi:
NULL
. [PMID: 11160640] - S Ohmori, Y Sugiyama, Y Morimoto. A protective effect against undesirable increase of dihydroetorphine permeation through damaged skin by using pressure-sensitive adhesive tape with an ethylene-vinyl acetate co-polymer membrane.
Biological & pharmaceutical bulletin.
2001 Jan; 24(1):78-83. doi:
10.1248/bpb.24.78
. [PMID: 11201250] - S Ohmori, T Hayashi, M Kawase, S Saito, K Sugibayashi, Y Morimoto. Transdermal delivery of the potent analgesic dihydroetorphine: kinetic analysis of skin permeation and analgesic effect in the hairless rat.
The Journal of pharmacy and pharmacology.
2000 Dec; 52(12):1437-49. doi:
10.1211/0022357001777649
. [PMID: 11197071] - S Ohmori, T Hayashi, M Kawase, S Saito, Y Morimoto. Quantitative determination of dihydroetorphine in rat plasma and brain by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Biomedical sciences and applications.
2000 Apr; 740(2):253-63. doi:
10.1016/s0378-4347(00)00129-8
. [PMID: 10821412] - L J Sha, Z X Zhang, L X Cheng. [Colonic dialysis therapy of Chinese herbal medicine in abstinance of heroin addicts--report of 75 cases].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
1997 Feb; 17(2):76-8. doi:
"
. [PMID: 9812660] - F Liu, Y Luo, J Feng, X Hu. Determination of dihydroetorphine in biological fluids by gas chromatography-mass spectrometry using selected-ion monitoring.
Journal of chromatography. B, Biomedical applications.
1996 Apr; 679(1-2):113-8. doi:
10.1016/0378-4347(96)00044-8
. [PMID: 8998549] - Y Luo, J L Feng, F Liu, X Y Hu. Identification of dihydroetorphine in biological fluids by gas chromatography-mass spectrometry.
Journal of chromatography. B, Biomedical applications.
1995 May; 667(2):344-8. doi:
10.1016/0378-4347(95)00024-d
. [PMID: 7663710] - Y Luo, J L Feng, F Liu, X Y Hu. [Monitoring of dihydroetorphine hydrochloride in biological fluid].
Yao xue xue bao = Acta pharmaceutica Sinica.
1994; 29(9):702-6. doi:
NULL
. [PMID: 7900540]