Mesocarb (BioDeep_00000771092)
代谢物信息卡片
化学式: C18H18N4O2 (322.1429688)
中文名称: 美沙卡伯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(CC1=CC=CC=C1)[N+]2=NOC(=C2)N=C(NC3=CC=CC=C3)[O-]
InChI: InChI=1S/C18H18N4O2/c1-14(12-15-8-4-2-5-9-15)22-13-17(24-21-22)20-18(23)19-16-10-6-3-7-11-16/h2-11,13-14H,12H2,1H3,(H-,19,20,21,23)
描述信息
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants
D002491 - Central Nervous System Agents > D000927 - Anticonvulsants
C78272 - Agent Affecting Nervous System > C66884 - Dopamine Agonist
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Svetlana A Appolonova, Pavel A Baranov, Natalia V Mesonzhnik, Daria O Brazhnikova, Grigory M Rodchenkov. Liquid chromatography electrospray ionization tandem mass spectrometry for the detection of mesocarb abuse in horse doping.
Drug testing and analysis.
2011 Oct; 3(10):717-23. doi:
10.1002/dta.345. [PMID: 21964865] - John A Gruner, Joanne R Mathiasen, Dorothy G Flood, Maciej Gasior. Characterization of pharmacological and wake-promoting properties of the dopaminergic stimulant sydnocarb in rats.
The Journal of pharmacology and experimental therapeutics.
2011 May; 337(2):380-90. doi:
10.1124/jpet.111.178947. [PMID: 21300706] - C Gómez, J Segura, N Monfort, T Suominen, A Leinonen, M Vahermo, J Yli-Kauhaluoma, R Ventura. Identification of free and conjugated metabolites of mesocarb in human urine by LC-MS/MS.
Analytical and bioanalytical chemistry.
2010 Aug; 397(7):2903-16. doi:
10.1007/s00216-010-3756-y. [PMID: 20496057] - Mikko Vahermo, Tina Suominen, Antti Leinonen, Jari Yli-Kauhaluoma. Synthesis and characterization of hydroxylated mesocarb metabolites for doping control.
Archiv der Pharmazie.
2009 Apr; 342(4):201-9. doi:
10.1002/ardp.200800144. [PMID: 19340833] - Min-Jung Kang, Yong Hee Hwang, Won Lee, Dong-Hyun Kim. Validation and application of a screening method for beta2-agonists, anti-estrogenic substances and mesocarb in human urine using liquid chromatography/tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2007; 21(2):252-64. doi:
10.1002/rcm.2834. [PMID: 17171780] - Alexey V Shpak, Svetlana A Appolonova, Vitaliy A Semenov. Validation of liquid chromatography-electrospray ionization ion trap mass spectrometry method for the determination of mesocarb in human plasma and urine.
Journal of chromatographic science.
2005 Jan; 43(1):11-21. doi:
10.1093/chromsci/43.1.11. [PMID: 15808002] - Svetlana A Appolonova, Alexey V Shpak, Vitaliy A Semenov. Liquid chromatography-electrospray ionization ion trap mass spectrometry for analysis of mesocarb and its metabolites in human urine.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2004 Feb; 800(1-2):281-9. doi:
10.1016/j.jchromb.2003.10.071. [PMID: 14698267] - V Bashkatova, A-M Mathieu-Kia, C Durand, J Penit-Soria. Neurochemical changes and neurotoxic effects of an acute treatment with sydnocarb, a novel psychostimulant: comparison with D-amphetamine.
Annals of the New York Academy of Sciences.
2002 Jun; 965(?):180-92. doi:
10.1111/j.1749-6632.2002.tb04160.x. [PMID: 12105094] - I S Morozov, L P Efimova, Iu A Salenko. [Effects of bromantane and sidnocarb on long-term operant conditioning and its vegetative correlates in rats].
Eksperimental'naia i klinicheskaia farmakologiia.
2000 May; 63(3):11-5. doi:
NULL. [PMID: 10934588] - F Musshoff. Illegal or legitimate use? Precursor compounds to amphetamine and methamphetamine.
Drug metabolism reviews.
2000 Feb; 32(1):15-44. doi:
10.1081/dmr-100100562. [PMID: 10711406] - S N Nagornev, S V Kalinkin, I P Bobrovnitskiĭ, S I Sytnik, T V Petrova, T A Orlova. [Metabolic effects of static physical load under the conditions of pharmakologicheskoĭ mobilization of physical endurance].
Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine.
2000; 34(5):18-24. doi:
". [PMID: 11816402] - H Pyo, S J Park, J Park, J K Yoo, B Yoon. Analysis of mesocarb analogues in urine and plasma of rats by high-performance liquid chromatography and thermospray liquid chromatography-mass spectrometry.
Journal of chromatography. B, Biomedical applications.
1996 Dec; 687(1):261-9. doi:
10.1016/s0378-4347(96)00257-5. [PMID: 9001972] - T G Dimitrov. Effect of mesocarb-theophylline combination on gonadal and gonadotropic hormone levels in male and female rats.
Methods and findings in experimental and clinical pharmacology.
1993 Apr; 15(3):189-92. doi:
NULL. [PMID: 8332035] - N F Turova, E Iu Misionzhnik, L A Ermolina, A V Aziavchik, V A Krasov. [Excretion of monoamines, their precursors and metabolites in the hyperactivity syndrome in mentally defective children].
Voprosy meditsinskoi khimii.
1988 Jan; 34(1):47-50. doi:
NULL. [PMID: 3369126] - M Polgár, L Vereczkey, L Szporny, G Czira, J Tamás, E Gács-Baitz, S Holly. Metabolism of mesocarb in the rat.
Xenobiotica; the fate of foreign compounds in biological systems.
1979 Aug; 9(8):511-9. doi:
10.3109/00498257909087265. [PMID: 42228]