mycophenolic acid glucuronide (BioDeep_00000770192)
代谢物信息卡片
mycophenolic acid glucuronide
化学式: C23H28O12 (496.1580688)
中文名称: 霉酸Β-D-葡萄糖醛酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)OC3C(C(C(C(O3)C(=O)O)O)O)O
InChI: InChI=1S/C23H28O12/c1-9(5-7-13(24)25)4-6-11-18(32-3)10(2)12-8-33-22(31)14(12)19(11)34-23-17(28)15(26)16(27)20(35-23)21(29)30/h4,15-17,20,23,26-28H,5-8H2,1-3H3,(H,24,25)(H,29,30)/b9-4+/t15-,16-,17+,20-,23+/m0/s1
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Joseph Berthier, Mehdi Benmameri, François-Ludovic Sauvage, Gabin Fabre, Benjamin Chantemargue, Hélène Arnion, Pierre Marquet, Patrick Trouillas, Nicolas Picard, Franck Saint-Marcoux. MRP4 is responsible for the efflux transport of mycophenolic acid β-d glucuronide (MPAG) from hepatocytes to blood.
Xenobiotica; the fate of foreign compounds in biological systems.
2021 Jan; 51(1):105-114. doi:
10.1080/00498254.2020.1813352. [PMID: 32820679] - Dionysius Subali, Mi Hye Kwon, Won Seok Bang, Hee Eun Kang. The pharmacokinetics of mycophenolic acid in rats with orotic acid induced nonalcoholic fatty liver disease.
Canadian journal of physiology and pharmacology.
2020 Mar; 98(3):169-176. doi:
10.1139/cjpp-2019-0383. [PMID: 31652406] - Yan Rong, Tony K L Kiang. Mechanisms of Metabolism Interaction Between p-Cresol and Mycophenolic Acid.
Toxicological sciences : an official journal of the Society of Toxicology.
2020 02; 173(2):267-279. doi:
10.1093/toxsci/kfz231. [PMID: 31742356] - Pâmela C Lukasewicz Ferreira, Flavia Valladao Thiesen, Thaina Tavares de Araujo, Domingos Otávio D'Ávila, Giovani Gadonski, Carmem Silvana A de Oliveira, Aline Rigon Zimmer, Pedro Eduardo Fröehlich. Comparison of plasma and oral fluid concentrations of mycophenolic acid and its glucuronide metabolite by LC-MS in kidney transplant patients.
European journal of clinical pharmacology.
2019 Apr; 75(4):553-559. doi:
10.1007/s00228-018-02614-9. [PMID: 30610275] - Jennifer E Slovak, Sol M Rivera-Velez, Julianne K Hwang, Nicolas F Villarino. Pharmacokinetics and pharmacodynamics of mycophenolic acid in healthy cats after twice-daily intravenous infusion of mycophenolate mofetil for three days.
American journal of veterinary research.
2018 Oct; 79(10):1093-1099. doi:
10.2460/ajvr.79.10.1093. [PMID: 30256137] - Lu-Yang Xu, Zheng Jiao, Fei-Yan Liu, Xiao-Yan Qiu, Li Ji, Ming Zhang. Pharmacokinetics Evaluation of Mycophenolic Acid and Its Glucuronide Metabolite in Chinese Renal Transplant Recipients Receiving Enteric-Coated Mycophenolate Sodium and Tacrolimus.
Therapeutic drug monitoring.
2018 10; 40(5):572-580. doi:
10.1097/ftd.0000000000000533. [PMID: 29847459] - Uttam Garg, Ada Munar, Clinton Frazee. Determination of Mycophenolic Acid and Mycophenolic Acid Glucuronide Using Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS).
Current protocols in toxicology.
2018 02; 75(?):18.21.1-18.21.8. doi:
10.1002/cptx.42. [PMID: 29512127] - Yasuaki Mino, Takafumi Naito, Kumiko Shimoyama, Noriyoshi Ogawa, Junichi Kawakami. Mycophenolic acid exposure and complement fraction C3 influence inosine 5'-monophosphate dehydrogenase activity in systemic lupus erythematosus.
Annals of clinical biochemistry.
2017 Jul; 54(4):490-494. doi:
10.1177/0004563216667753. [PMID: 27538768] - L R Ruschel, V M Schmitt, A B Silva, C S A Oliveira, K Flach, D O d'Avila, F V Thiesen. Study on the association of UGT1A9 gene c.98T>C polymorphism and mycophenolic acid plasma levels in renal transplant patients.
Genetics and molecular research : GMR.
2017 May; 16(2):. doi:
10.4238/gmr16029598. [PMID: 28613375] - Olesja Rissling, Steffen Bauer, Maria Shipkova, Petra Glander, Marco Mai, Pia Hambach, Klemens Budde. Simultaneous determination of mycophenolate and its metabolite mycophenolate-7-o-glucuronide with an isocratic HPLC-UV-based method in human plasma and stability evaluation.
Scandinavian journal of clinical and laboratory investigation.
2016 Dec; 76(8):612-619. doi:
10.1080/00365513.2016.1230775. [PMID: 27676419] - Camille Girard-Bock, Marie-Odile Benoit-Biancamano, Lyne Villeneuve, Sylvie Desjardins, Chantal Guillemette. A Rare UGT2B7 Variant Creates a Novel N-Glycosylation Site at Codon 121 with Impaired Enzyme Activity.
Drug metabolism and disposition: the biological fate of chemicals.
2016 12; 44(12):1867-1871. doi:
10.1124/dmd.116.071860. [PMID: 27612916] - Olesja Rissling, Petra Glander, Pia Hambach, Marco Mai, Susanne Brakemeier, Daniela Klonower, Fabian Halleck, Eugenia Singer, Eva-Vanessa Schrezenmeier, Michael Dürr, Hans-Hellmut Neumayer, Klemens Budde. No relevant pharmacokinetic interaction between pantoprazole and mycophenolate in renal transplant patients: a randomized crossover study.
British journal of clinical pharmacology.
2015 Nov; 80(5):1086-96. doi:
10.1111/bcp.12664. [PMID: 25913040] - Jolanta Zegarska, Ewa Hryniewiecka, Dorota Żochowska, Wlodzimierz Tszyrsznic, Radosław Jaźwiec, Agnieszka Borowiec, Emilia Pawłowska, Michał Dadlez, Leszek Pączek. Mycophenolic Acid Metabolites Acyl-Glucuronide and Glucoside Affect the Occurrence of Infectious Complications and Bone Marrow Dysfunction in Liver Transplant Recipients.
Annals of transplantation.
2015 Aug; 20(?):483-92. doi:
10.12659/aot.894954. [PMID: 26313036] - Xiao-chun Xie, Jun Li, Hong-yang Wang, Hong-liang Li, Jing Liu, Qian Fu, Jia-wen Huang, Chen Zhu, Guo-ping Zhong, Xue-ding Wang, Ping-ping Sun, Min Huang, Chang-xi Wang, Jia-li Li. Associations of UDP-glucuronosyltransferases polymorphisms with mycophenolate mofetil pharmacokinetics in Chinese renal transplant patients.
Acta pharmacologica Sinica.
2015 May; 36(5):644-50. doi:
10.1038/aps.2015.7. [PMID: 25864649] - Kathleen M Tornatore, Calvin J Meaney, Gregory E Wilding, Shirley S Chang, Aijaz Gundroo, Louise M Cooper, Vanessa Gray, Karen Shin, Gerald J Fetterly, Joshua Prey, Kimberly Clark, Rocco C Venuto. Influence of sex and race on mycophenolic acid pharmacokinetics in stable African American and Caucasian renal transplant recipients.
Clinical pharmacokinetics.
2015 Apr; 54(4):423-34. doi:
10.1007/s40262-014-0213-7. [PMID: 25511793] - Yasuaki Mino. [Optimization of Immunosuppression and the Prevention of Fungal Infection in Autoimmune Diseases].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2015; 135(10):1123-7. doi:
10.1248/yakushi.15-00193. [PMID: 26423867] - Norikazu Matsunaga, Sho Wada, Takeo Nakanishi, Miho Ikenaga, Mikio Ogawa, Ikumi Tamai. Mathematical modeling of the in vitro hepatic disposition of mycophenolic acid and its glucuronide in sandwich-cultured human hepatocytes.
Molecular pharmaceutics.
2014 Feb; 11(2):568-79. doi:
10.1021/mp400513k. [PMID: 24320552] - Amitava Dasgupta, Myrtle Johnson, Gertie Tso. Mathematical equations to calculate true mycophenolic acid concentration in human plasma by using two immunoassays with different cross-reactivities with acyl glucuronide metabolite: comparison of calculated values with values obtained by using an HPLC-UV method.
Journal of clinical laboratory analysis.
2013 Jul; 27(4):290-3. doi:
10.1002/jcla.21599. [PMID: 23852786] - Chirag G Patel, Ken Ogasawara, Fatemeh Akhlaghi. Mycophenolic acid glucuronide is transported by multidrug resistance-associated protein 2 and this transport is not inhibited by cyclosporine, tacrolimus or sirolimus.
Xenobiotica; the fate of foreign compounds in biological systems.
2013 Mar; 43(3):229-35. doi:
10.3109/00498254.2012.713531. [PMID: 22934787] - Helio Tedesco-Silva, Claudia Rosso Felipe, Alan Slade, Robert L Schmouder, Jose Osmar Medina Pestana. Chronopharmacokinetics of mycophenolic acid and its glucuronide and acyl glucuronide metabolites in kidney transplant recipients converted from cyclosporine to everolimus.
Therapeutic drug monitoring.
2012 Dec; 34(6):652-9. doi:
10.1097/ftd.0b013e3182706ef1. [PMID: 23131696] - M G Kees, T Steinke, S Moritz, K Rupprecht, E M Paulus, F Kees, M Bucher, L Faerber. Omeprazole impairs the absorption of mycophenolate mofetil but not of enteric-coated mycophenolate sodium in healthy volunteers.
Journal of clinical pharmacology.
2012 Aug; 52(8):1265-72. doi:
10.1177/0091270011412968. [PMID: 21903891] - Martin H J Wiesen, Fedja Farowski, Markus Feldkötter, Bernd Hoppe, Carsten Müller. Liquid chromatography-tandem mass spectrometry method for the quantification of mycophenolic acid and its phenolic glucuronide in saliva and plasma using a standardized saliva collection device.
Journal of chromatography. A.
2012 Jun; 1241(?):52-9. doi:
10.1016/j.chroma.2012.04.008. [PMID: 22552204] - Y Mino, T Naito, K Shimoyama, N Ogawa, J Kawakami. Effective plasma concentrations of mycophenolic acid and its glucuronide in systemic lupus erythematosus patients in the remission-maintenance phase.
Journal of clinical pharmacy and therapeutics.
2012 Apr; 37(2):217-20. doi:
10.1111/j.1365-2710.2011.01269.x. [PMID: 21517926] - Jacek Klepacki, Jelena Klawitter, Jamie Bendrick-Peart, Bjorn Schniedewind, Svenja Heischmann, Touraj Shokati, Uwe Christians, Jost Klawitter. A high-throughput U-HPLC-MS/MS assay for the quantification of mycophenolic acid and its major metabolites mycophenolic acid glucuronide and mycophenolic acid acyl-glucuronide in human plasma and urine.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2012 Feb; 883-884(?):113-9. doi:
10.1016/j.jchromb.2011.07.021. [PMID: 21839692] - Erica D Greanya, Eric Poulin, Nilufar Partovi, R Jean Shapiro, Mai Al-Khatib, Mary H H Ensom. Pharmacokinetics of tacrolimus and mycophenolate mofetil in renal transplant recipients on a corticosteroid-free regimen.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
2012 Jan; 69(2):134-42. doi:
10.2146/ajhp110287. [PMID: 22215359] - Monica Cortinovis, Eliana Gotti, Silvia Pradini, Flavio Gaspari, Norberto Perico. Renal graft function and low-dose cyclosporine affect mycophenolic acid pharmacokinetics in kidney transplantation.
Transplantation.
2011 Sep; 92(5):550-6. doi:
10.1097/tp.0b013e318225dbd0. [PMID: 21709602] - Kathleen M Tornatore, Patcharaporn Sudchada, Kiran Dole, Robin DiFrancesco, Nicolae Leca, Aijaz C Gundroo, Ryan T Danison, Kris Attwood, Gregory E Wilding, Julia Zack, Alan Forrest, Rocco C Venuto. Mycophenolic acid pharmacokinetics during maintenance immunosuppression in African American and Caucasian renal transplant recipients.
Journal of clinical pharmacology.
2011 Aug; 51(8):1213-22. doi:
10.1177/0091270010382909. [PMID: 21209244] - Y Mino, T Naito, A Otsuka, T Takayama, S Ozono, Y Kagawa, J Kawakami. Cyclosporine alters correlation between free and total mycophenolic acid in kidney transplant recipients in the initial phase.
Journal of clinical pharmacy and therapeutics.
2011 Apr; 36(2):217-24. doi:
10.1111/j.1365-2710.2010.01168.x. [PMID: 21366651] - Xavier Delavenne, Ludivine Juthier, Bertrand Pons, Christophe Mariat, Thierry Basset. UPLC MS/MS method for quantification of mycophenolic acid and metabolites in human plasma: Application to pharmacokinetic study.
Clinica chimica acta; international journal of clinical chemistry.
2011 Jan; 412(1-2):59-65. doi:
10.1016/j.cca.2010.09.041. [PMID: 20937266] - Jun-wei Gao, Zhi-hai Peng, Xiao-yu Li, Bo Sun, Yan-kun Guo, Gao-lin Liu. Simultaneous determination of mycophenolic acid and its metabolites by HPLC and pharmacokinetic studies in rat plasma and bile.
Archives of pharmacal research.
2011 Jan; 34(1):59-69. doi:
10.1007/s12272-011-0107-2. [PMID: 21468916] - Takafumi Naito. [Optimal immunosuppressive therapy based on pharmacokinetics and pharmacodynamics of antimetabolites in clinical practice].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2010 Dec; 130(12):1695-700. doi:
10.1248/yakushi.130.1695. [PMID: 21139397] - M C Raggi, S B Siebert, D K Abendroth, W Steimer, H Friess, S G Thorban. Neither mycophenolate acyl-glucuronide levels nor their areas under the curve are responsible for the gastrointestinal side effects in kidney transplant recipients receiving EC-MPA: a prospective trial.
Transplantation proceedings.
2010 Dec; 42(10):4049-52. doi:
10.1016/j.transproceed.2010.09.029. [PMID: 21168624] - Bing Chen, ZhiDong Gu, Hao Chen, WeiXia Zhang, XiaoJing Fen, WeiMin Cai, QiShi Fan. Establishment of high-performance liquid chromatography and enzyme multiplied immunoassay technology methods for determination of free mycophenolic acid and its application in Chinese liver transplant recipients.
Therapeutic drug monitoring.
2010 Oct; 32(5):653-60. doi:
10.1097/ftd.0b013e3181f01397. [PMID: 20814351] - Joachim Kuhn, Christian Götting, Knut Kleesiek. Sample cleanup-free determination of mycophenolic acid and its glucuronide in serum and plasma using the novel technology of ultra-performance liquid chromatography-electrospray ionization tandem mass spectrometry.
Talanta.
2010 Mar; 80(5):1894-8. doi:
10.1016/j.talanta.2009.10.040. [PMID: 20152429] - Katherine A Barraclough, Katie J Lee, Christine E Staatz. Pharmacogenetic influences on mycophenolate therapy.
Pharmacogenomics.
2010 Mar; 11(3):369-90. doi:
10.2217/pgs.10.9. [PMID: 20235793] - Pamala A Jacobson, Jiayin Huang, Juan Wu, Miae Kim, Brent Logan, Amin Alousi, Michael Grimley, Javier Bolaños-Meade, Vincent Ho, John E Levine, Daniel Weisdorf. Mycophenolate pharmacokinetics and association with response to acute graft-versus-host disease treatment from the Blood and Marrow Transplant Clinical Trials Network.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2010 Mar; 16(3):421-9. doi:
10.1016/j.bbmt.2009.11.010. [PMID: 19925875] - Mohamed-Eslam F Mohamed, Reginald F Frye. Inhibition of intestinal and hepatic glucuronidation of mycophenolic acid by Ginkgo biloba extract and flavonoids.
Drug metabolism and disposition: the biological fate of chemicals.
2010 Feb; 38(2):270-5. doi:
10.1124/dmd.109.030080. [PMID: 19889883] - Maria Shipkova, Ekkehard Schütz, Ingo Besenthal, Peter Fraunberger, Eberhard Wieland. Investigation of the crossreactivity of mycophenolic acid glucuronide metabolites and of mycophenolate mofetil in the Cedia MPA assay.
Therapeutic drug monitoring.
2010 Feb; 32(1):79-85. doi:
10.1097/ftd.0b013e3181cc342a. [PMID: 20042920] - Catherine A Hammett-Stabler, Diane Ciuffetti Geis, James C Ritchie, Christine Papadea. Monitoring of mycophenolate acid in serum or plasma using LC tandem mass spectrometry.
Methods in molecular biology (Clifton, N.J.).
2010; 603(?):379-87. doi:
10.1007/978-1-60761-459-3_37. [PMID: 20077090] - Michal J Figurski, Magdalena Korecka, Leona Fields, Teresa Waligórska, Leslie M Shaw. High-performance liquid chromatography-mass spectroscopy/mass spectroscopy method for simultaneous quantification of total or free fraction of mycophenolic acid and its glucuronide metabolites.
Therapeutic drug monitoring.
2009 Dec; 31(6):717-26. doi:
10.1097/ftd.0b013e3181ba9a0e. [PMID: 19809389] - Brenda C M de Winter, Teun van Gelder, Ferdi Sombogaard, Leslie M Shaw, Reinier M van Hest, Ron A A Mathot. Pharmacokinetic role of protein binding of mycophenolic acid and its glucuronide metabolite in renal transplant recipients.
Journal of pharmacokinetics and pharmacodynamics.
2009 Dec; 36(6):541-64. doi:
10.1007/s10928-009-9136-6. [PMID: 19904584] - Korbinian Rupprecht, Christoph Schmidt, Anne Raspé, Frank Schweda, Maria Shipkova, Wolfgang Fischer, Michael Bucher, Frieder Kees, Lothar Faerber. Bioavailability of mycophenolate mofetil and enteric-coated mycophenolate sodium is differentially affected by pantoprazole in healthy volunteers.
Journal of clinical pharmacology.
2009 Oct; 49(10):1196-201. doi:
10.1177/0091270009344988. [PMID: 19783713] - T Baczkowska, A Sadowska, A Perkowska-Ptasinska, Z Lewandowski, T Cieciura, J Pazik, E Wazna, O Przybyl Kozinska, E Nowacka Cieciura, A Chmura, M Durlik. Optimal mycophenolic acid and mycophenolic acid glucuronide levels at the early period after kidney transplantation are the key contributors to improving long-term outcomes.
Transplantation proceedings.
2009 Oct; 41(8):3019-23. doi:
10.1016/j.transproceed.2009.08.009. [PMID: 19857666] - Jae H Chang, Phillip Yoo, Theresa Lee, Wendy Klopf, Denise Takao. The role of pH in the glucuronidation of raloxifene, mycophenolic acid and ezetimibe.
Molecular pharmaceutics.
2009 Jul; 6(4):1216-27. doi:
10.1021/mp900065b. [PMID: 19449843] - Wai-Ping Yau, Anantharaman Vathsala, Huei-Xin Lou, Shufeng Zhou, Eli Chan. Mechanism-based enterohepatic circulation model of mycophenolic acid and its glucuronide metabolite: assessment of impact of cyclosporine dose in Asian renal transplant patients.
Journal of clinical pharmacology.
2009 Jun; 49(6):684-99. doi:
10.1177/0091270009332813. [PMID: 19386625] - Takafumi Naito, Yasuaki Mino, Atsushi Otsuka, Tomomi Ushiyama, Toshiki Ito, Seiichiro Ozono, Yoshiyuki Kagawa, Junichi Kawakami. Impact of calcineurin inhibitors on urinary excretion of mycophenolic acid and its glucuronide in kidney transplant recipients.
Journal of clinical pharmacology.
2009 Jun; 49(6):710-8. doi:
10.1177/0091270009335003. [PMID: 19451405] - Melanie S Joy, Tandrea Hilliard, Yichun Hu, Susan L Hogan, Jinzhao Wang, Ronald J Falk, Philip C Smith. Influence of clinical and demographic variables on mycophenolic acid pharmacokinetics in antineutrophil cytoplasmic antibody-associated vasculitis.
The Annals of pharmacotherapy.
2009 Jun; 43(6):1020-7. doi:
10.1345/aph.1l699. [PMID: 19491317] - Yasuaki Mino, Takafumi Naito, Atsushi Otsuka, Tomomi Ushiyama, Seiichiro Ozono, Yoshiyuki Kagawa, Junichi Kawakami. Cyclosporine concentration-dependent increase in concentration ratio of mycophenolic acid acyl and phenol glucuronides to mycophenolic acid in stable kidney transplant recipients.
Clinical biochemistry.
2009 May; 42(7-8):595-601. doi:
10.1016/j.clinbiochem.2008.11.013. [PMID: 19100248] - Flora T Musuamba, Annick Rousseau, Jean-Louis Bosmans, Jean-Jacques Senessael, Jean Cumps, Pierre Marquet, Pierre Wallemacq, Roger K Verbeeck. Limited sampling models and Bayesian estimation for mycophenolic acid area under the curve prediction in stable renal transplant patients co-medicated with ciclosporin or sirolimus.
Clinical pharmacokinetics.
2009; 48(11):745-58. doi:
10.2165/11318060-000000000-00000. [PMID: 19817503] - Joachim Kuhn, Christian Prante, Knut Kleesiek, Christian Götting. Measurement of mycophenolic acid and its glucuronide using a novel rapid liquid chromatography-electrospray ionization tandem mass spectrometry assay.
Clinical biochemistry.
2009 Jan; 42(1-2):83-90. doi:
10.1016/j.clinbiochem.2008.10.004. [PMID: 18996104] - Melanie S Joy, Tandrea Hilliard, Yichun Hu, Susan L Hogan, Mary Anne Dooley, Ronald J Falk, Philip C Smith. Pharmacokinetics of mycophenolic acid in patients with lupus nephritis.
Pharmacotherapy.
2009 Jan; 29(1):7-16. doi:
10.1592/phco.29.1.7. [PMID: 19113793] - Yasuaki Mino, Takafumi Naito, Tomomi Matsushita, Atsushi Otsuka, Tomomi Ushiyama, Seiichiro Ozono, Akira Hishida, Yoshiyuki Kagawa, Junichi Kawakami. Comparison of pharmacokinetics of mycophenolic acid and its glucuronide between patients with lupus nephritis and with kidney transplantation.
Therapeutic drug monitoring.
2008 Dec; 30(6):656-61. doi:
10.1097/ftd.0b013e31818b8244. [PMID: 18978521] - W-X Zhang, B Chen, Z Jin, Z Yu, X Wang, H Chen, A Mao, W Cai. Influence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients.
Xenobiotica; the fate of foreign compounds in biological systems.
2008 Nov; 38(11):1422-36. doi:
10.1080/00498250802488585. [PMID: 18946804] - Masatomo Miura, Hideaki Kagaya, Shigeru Satoh, Kazuyuki Inoue, Mitsuru Saito, Tomonori Habuchi, Toshio Suzuki. Influence of drug transporters and UGT polymorphisms on pharmacokinetics of phenolic glucuronide metabolite of mycophenolic acid in Japanese renal transplant recipients.
Therapeutic drug monitoring.
2008 Oct; 30(5):559-64. doi:
10.1097/ftd.0b013e3181838063. [PMID: 18695635] - Madelon van Agteren, Victor W Armstrong, Ron H N van Schaik, Hans de Fijter, Anders Hartmann, Martin Zeier, Klemens Budde, Dirk Kuypers, Przemyslav Pisarski, Yann Le Meur, Marloes van der Werf, Richard D Mamelok, Michael Oellerich, Teun van Gelder. AcylMPAG plasma concentrations and mycophenolic acid-related side effects in patients undergoing renal transplantation are not related to the UGT2B7-840G>A gene polymorphism.
Therapeutic drug monitoring.
2008 Aug; 30(4):439-44. doi:
10.1097/ftd.0b013e318180c709. [PMID: 18641546] - Ljiljana Zivanović, Ana Licanski, Mira Zecević, Biljana Jocić, Mirjana Kostić. Application of experimental design in optimization of solid phase extraction of mycophenolic acid and mycophenolic acid glucuronide from human urine and plasma and SPE-RP-HPLC method validation.
Journal of pharmaceutical and biomedical analysis.
2008 Jul; 47(3):575-85. doi:
10.1016/j.jpba.2008.01.046. [PMID: 18356001] - Jian Wang, Michael Figurski, Leslie M Shaw, Gilbert J Burckart. The impact of P-glycoprotein and Mrp2 on mycophenolic acid levels in mice.
Transplant immunology.
2008 Jul; 19(3-4):192-6. doi:
10.1016/j.trim.2008.05.009. [PMID: 18586494] - Ashok Jain, Raman Venkataramanan, Rajeev Sharma, Tai Kwong, Peter Abt, Mark Orloff, Randeep Kashyap, Georgious Tsoulfas, Adel Bozorgzadeh. Pharmacokinetics of mycophenolic acid in live donor liver transplant patients vs deceased donor liver transplant patients.
Journal of clinical pharmacology.
2008 May; 48(5):547-52. doi:
10.1177/0091270008315317. [PMID: 18440919] - Christin C Rogers, Rita R Alloway, J Wesley Alexander, Michael Cardi, Jennifer Trofe, Alexander A Vinks. Pharmacokinetics of mycophenolic acid, tacrolimus and sirolimus after gastric bypass surgery in end-stage renal disease and transplant patients: a pilot study.
Clinical transplantation.
2008 May; 22(3):281-91. doi:
10.1111/j.1399-0012.2007.00783.x. [PMID: 18482049] - Yasuaki Mino, Takafumi Naito, Tomomi Matsushita, Yoshiyuki Kagawa, Junichi Kawakami. Simultaneous determination of mycophenolic acid and its glucuronides in human plasma using isocratic ion pair high-performance liquid chromatography.
Journal of pharmaceutical and biomedical analysis.
2008 Feb; 46(3):603-8. doi:
10.1016/j.jpba.2007.11.018. [PMID: 18164890] - Fawzy A Elbarbry, Ahmed S Shoker. Liquid chromatographic determination of mycophenolic acid and its metabolites in human kidney transplant plasma: pharmacokinetic application.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2007 Nov; 859(2):276-81. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2007 Nov; 859(1):42-51. doi:
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Transplantation proceedings.
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American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
2007 Jul; 7(7):1822-31. doi:
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Biochemical pharmacology.
2007 Jun; 74(1):161-8. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2007 Jun; 852(1-2):674-8. doi:
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Pharmacogenetics and genomics.
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Drug metabolism and disposition: the biological fate of chemicals.
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Therapeutic drug monitoring.
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European journal of clinical pharmacology.
2007 Jan; 63(1):27-37. doi:
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Clinical pharmacology and therapeutics.
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Drug metabolism and pharmacokinetics.
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Clinical chemistry.
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The Annals of pharmacotherapy.
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Drug metabolism and disposition: the biological fate of chemicals.
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International journal of clinical pharmacology and therapeutics.
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2006 Mar; 41(3):272-6. doi:
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Biological & pharmaceutical bulletin.
2006 Feb; 29(2):275-80. doi:
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2006 Feb; 31(1):27-34. doi:
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2005 Dec; 9(6):780-7. doi:
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2005 Aug; 43(8):379-88. doi:
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American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
2005 May; 5(5):987-94. doi:
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British journal of clinical pharmacology.
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Therapeutic drug monitoring.
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