SPDP (BioDeep_00000768696)

   


代谢物信息卡片


N-Succinimidyl 3-(2-pyridyldithio)propionate

化学式: C12H12N2O4S2 (312.0238472)
中文名称: 3-(2-吡啶二硫代)丙酸 N-琥珀酰亚胺酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC(=O)N(C1=O)OC(=O)CCSSC2=CC=CC=N2
InChI: InChI=1S/C12H12N2O4S2/c15-10-4-5-11(16)14(10)18-12(17)6-8-19-20-9-3-1-2-7-13-9/h1-3,7H,4-6,8H2

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D003432 - Cross-Linking Reagents

同义名列表

2 个代谢物同义名

N-Succinimidyl 3-(2-pyridyldithio)propionate; SPDP



数据库引用编号

2 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Meng-Yang Li, Hao-Zhe Cui, Jia-Ning Hao, Da-Bin Xu, En-Li Zhang, Zhu-Zeng Yin, Zhi-Ming Zhao. 'Parenchyma transection-first' strategy is superior to 'tunnel-first' strategy in robotic spleen-preserving distal pancreatectomy with conservation of splenic vessels. Hepatobiliary & pancreatic diseases international : HBPD INT. 2023 Dec; 22(6):639-644. doi: 10.1016/j.hbpd.2023.06.007. [PMID: 37353372]
  • Geeti Bansal, Jennifer E I Wright, Sufeng Zhang, Ronald F Zernicke, Hasan Uludag. Imparting mineral affinity to proteins with thiol-labile disulfide linkages. Journal of biomedical materials research. Part A. 2005 Sep; 74(4):618-28. doi: 10.1002/jbm.a.30334. [PMID: 16037953]
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  • J Andersson, R Larsson, R Richter, K N Ekdahl, B Nilsson. Binding of a model regulator of complement activation (RCA) to a biomaterial surface: surface-bound factor H inhibits complement activation. Biomaterials. 2001 Sep; 22(17):2435-43. doi: 10.1016/s0142-9612(00)00431-2. [PMID: 11511041]
  • M Mercadal, J C Domingo, J Petriz, J Garcia, M A de Madariaga. Preparation of immunoliposomes bearing poly(ethylene glycol)-coupled monoclonal antibody linked via a cleavable disulfide bond for ex vivo applications. Biochimica et biophysica acta. 2000 Dec; 1509(1-2):299-310. doi: 10.1016/s0005-2736(00)00305-9. [PMID: 11118541]
  • J F Liang, Y T Li, M E Connell, V C Yang. Synthesis and characterization of positively charged tPA as a prodrug using heparin/protamine-based drug delivery system. AAPS pharmSci. 2000; 2(1):E7. doi: 10.1208/ps020107. [PMID: 11741223]
  • I Martin, E I Pécheur, J M Ruysschaert, D Hoekstra. Membrane fusion induced by a short fusogenic peptide is assessed by its insertion and orientation into target bilayers. Biochemistry. 1999 Jul; 38(29):9337-47. doi: 10.1021/bi9829534. [PMID: 10413508]
  • D H Na, B H Woo, K C Lee. Quantitative analysis of derivatized proteins prepared with pyridyl disulfide-containing cross-linkers by high-performance liquid chromatography. Bioconjugate chemistry. 1999 Mar; 10(2):306-10. doi: 10.1021/bc980029g. [PMID: 10077481]
  • M G Rosenblum, J W Marks, L H Cheung. Comparative cytotoxicity and pharmacokinetics of antimelanoma immunotoxins containing either natural or recombinant gelonin. Cancer chemotherapy and pharmacology. 1999; 44(4):343-8. doi: 10.1007/s002800050987. [PMID: 10447583]
  • J A Neff, K D Caldwell, P A Tresco. A novel method for surface modification to promote cell attachment to hydrophobic substrates. Journal of biomedical materials research. 1998 Jun; 40(4):511-9. doi: 10.1002/(sici)1097-4636(19980615)40:4<511::aid-jbm1>3.0.co;2-i. [PMID: 9599026]
  • F Li, Z Luo, J Zhang. [Conjugation and identification of the surface protein antigen P1 from streptococcus mutans MT6R with the cholera toxin B subunit and procholeragenoid]. Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology. 1997 Feb; 15(1):45-7. doi: NULL. [PMID: 11480059]
  • Y J Buechler, B A Sosnowski, K D Victor, Z Parandoosh, S J Bussell, C Shen, M Ryder, L L Houston. Synthesis and characterization of a homogeneous chemical conjugate between basic fibroblast growth factor and saporin. European journal of biochemistry. 1995 Dec; 234(3):706-13. doi: 10.1111/j.1432-1033.1995.706_a.x. [PMID: 8575426]
  • P Sarti, A Molinari, G Arancia, A Meloni, G Citro. A modified spectroscopic method for the determination of the transbilayer distribution of phosphatidylethanolamine in soya-bean asolectin small unilamellar vesicles. The Biochemical journal. 1995 Dec; 312 ( Pt 2)(?):643-8. doi: 10.1042/bj3120643. [PMID: 8526881]
  • T Whalley, A Sokoloff. The N-ethylmaleimide-sensitive protein thiol groups necessary for sea-urchin egg cortical-granule exocytosis are highly exposed to the medium and are required for triggering by Ca2+. The Biochemical journal. 1994 Sep; 302 ( Pt 2)(?):391-6. doi: 10.1042/bj3020391. [PMID: 7522436]
  • D J Flavell, D A Boehm, K Okayama, J A Kohler, S U Flavell. Therapy of human T-cell acute lymphoblastic leukaemia in severe combined immunodeficient mice with two different anti-CD7-saporin immunotoxins containing hindered or non-hindered disulphide cross-linkers. International journal of cancer. 1994 Aug; 58(3):407-14. doi: 10.1002/ijc.2910580317. [PMID: 7519586]
  • V Singh, R Curtiss. Hormonotoxins: the role of positive charge of lysine residue on the immunological, biological and cytotoxic properties of ovine lutropin-S-S-gelonin conjugates. Molecular and cellular biochemistry. 1994 Jan; 130(1):91-101. doi: 10.1007/bf01084272. [PMID: 8190124]
  • V Singh, A K Mavila, S K Kar. Comparison of the cytotoxic effect of hormonotoxins prepared with the use of heterobifunctional cross-linking agents N-succinimidyl 3-(2-pyridyldithio)propionate and N-succinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate. Bioconjugate chemistry. 1993 Nov; 4(6):473-82. doi: 10.1021/bc00024a009. [PMID: 8305517]
  • V Singh, R Curtiss. Disulfide linked alpha oLH-gelonin conjugate failed to recombine with beta oLH subunit to generate bioeffective hormonotoxin. Molecular and cellular biochemistry. 1993 Mar; 120(2):95-102. doi: 10.1007/bf00926081. [PMID: 7683746]
  • G V Betageri, C D Black, J Szebeni, L M Wahl, J N Weinstein. Fc-receptor-mediated targeting of antibody-bearing liposomes containing dideoxycytidine triphosphate to human monocyte/macrophages. The Journal of pharmacy and pharmacology. 1993 Jan; 45(1):48-53. doi: 10.1111/j.2042-7158.1993.tb03678.x. [PMID: 8094446]
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  • V Singh. Hormonotoxins: synthesis, characterization and bioefficacy of some defined disulfide linked conjugates of ovine LH with a ribosome inactivating protein, gelonin. Indian journal of experimental biology. 1991 Oct; 29(10):916-25. doi: ". [PMID: 1814832]
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  • V Singh, M R Sairam. Hormonotoxins. Effects of modifying the gonadotropin alpha-subunit on the generation of lutropin-toxin conjugates. International journal of peptide and protein research. 1990 Jan; 35(1):46-51. doi: ". [PMID: 2323883]
  • V Singh, M R Sairam. Effects of thiolation on the immunoreactivity of the ribosome-inactivating protein gelonin. The Biochemical journal. 1989 Oct; 263(2):417-23. doi: 10.1042/bj2630417. [PMID: 2597114]
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  • V Singh, M R Sairam, G N Bhargavi, R G Akhras. Hormonotoxins. Preparation and characterization of ovine luteinizing hormone-gelonin conjugate. The Journal of biological chemistry. 1989 Feb; 264(6):3089-95. doi: ". [PMID: 2914944]
  • Y Reiter, Z Fishelson. Killing of human tumor cells by antibody C3b conjugates and human complement. Targeted diagnosis and therapy. 1989; 2(?):119-35. doi: NULL. [PMID: 2519543]
  • V Singh, M R Sairam. Hormonotoxins. I. Strategy for synthesis of ovine luteinizing hormone--gelonin conjugate bearing the toxin in the beta-subunit. International journal of peptide and protein research. 1989 Jan; 33(1):22-8. doi: 10.1111/j.1399-3011.1989.tb00679.x. [PMID: 2722397]
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  • A F Habeeb. A novel preparation of immunoadsorbents. Controlled coupling of proteins to Sepharose-gelatin by heterobifunctional reagent. Biochimica et biophysica acta. 1981 Apr; 673(4):527-38. doi: 10.1016/0304-4165(81)90484-0. [PMID: 7194690]
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