Betahistine mesilate (BioDeep_00000766486)
代谢物信息卡片
Betahistine mesilate
化学式: C10H20N2O6S2 (328.0763)
中文名称: 甲磺酸倍他司汀
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CNCCC1=CC=CC=N1.CS(=O)(=O)O.CS(=O)(=O)O
InChI: 2*1H3,(H,2,3,4)
描述信息
D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D017442 - Histamine Agonists
D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
Betahistine mesylate is an orally active histamine H1 receptor agonist and a H3 receptor antagonist[1]. Betahistine mesylate is used for the study of rheumatoid arthritis (RA)[3].
同义名列表
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:31274
- KEGGdrug: D01592
- KEGGdrug: D87714
- PubChem: 198334
- ChEMBL: CHEMBL4303472
- MeSH: Betahistine
- CAS: 54856-23-4
- medchemexpress: HY-D0237
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Dong Wu, Bo Liu, Yunqing Wu, Yu Wang, Jingyi Sun, Jun Yang, Jinping Duan, Gang Liu, Kai Cao, Yi Zhang, Peijing Rong. Meniere Disease treated with transcutaneous auricular vagus nerve stimulation combined with betahistine Mesylate: A randomized controlled trial.
Brain stimulation.
2023 Nov; 16(6):1576-1584. doi:
10.1016/j.brs.2023.10.003. [PMID: 37838094] - Yueqing Su, Chao Deng, Xuemei Liu, Jiamei Lian. Epigenetic Histone Methylation of PPARγ and CPT1A Signaling Contributes to Betahistine Preventing Olanzapine-Induced Dyslipidemia.
International journal of molecular sciences.
2023 May; 24(11):. doi:
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Medicine.
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Epilepsy & behavior : E&B.
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Clinical hemorheology and microcirculation.
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PloS one.
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10.1371/journal.pone.0104160. [PMID: 25084453] - Jiamei Lian, Xu-Feng Huang, Nagesh Pai, Chao Deng. Effects of olanzapine and betahistine co-treatment on serotonin transporter, 5-HT2A and dopamine D2 receptor binding density.
Progress in neuro-psychopharmacology & biological psychiatry.
2013 Dec; 47(?):62-8. doi:
10.1016/j.pnpbp.2013.08.005. [PMID: 23994047] - Israfil Orhan, Salih Aydın, Gökhan Altın, Fahrettin Yılmaz. [An efficacy comparison of betahistin, trimetazidine and ginkgo biloba extract in patients with tinnitus].
Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat.
2013 May; 23(3):143-7. doi:
10.5606/kbbihtisas.2013.03064. [PMID: 23682937] - Ligia Val, Lu Shi Chen, Gustavo Duarte Mendes, Gilberto De Nucci. Comparative bioavailability of betahistine tablet formulations administered in healthy subjects.
Arzneimittel-Forschung.
2010; 60(7):440-4. doi:
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10.1055/s-0031-1296821. [PMID: 15727161] - H J R Hoenders, J Wilterdink. [Delirium in a 73-year-old man after many years of unwise use of betahistine].
Nederlands tijdschrift voor geneeskunde.
2004 Nov; 148(47):2338-41. doi:
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