Omeprazole sodium (BioDeep_00000766463)
代谢物信息卡片
Esomeprazole sodium
化学式: C17H18N3NaO3S (367.0967)
中文名称: 埃索美拉唑钠
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.[Na+]
InChI: +1
描述信息
C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent > C29723 - Proton Pump Inhibitor
D005765 - Gastrointestinal Agents > D000897 - Anti-Ulcer Agents
D004791 - Enzyme Inhibitors > D054328 - Proton Pump Inhibitors
Omeprazole sodium (H 16868 sodium), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole sodium shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM[1]. Omeprazole sodium also inhibits growth of Gram-positive and Gram-negative bacteria[2]. Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)[3].
同义名列表
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:31934
- KEGGdrug: D70375
- KEGGdrug: D01207
- KEGGdrug: D04056
- PubChem: 10959536
- PubChem: 23674541
- ChEMBL: CHEMBL2105294
- ChEMBL: CHEMBL1200470
- MeSH: Omeprazole
- MeSH: Esomeprazole
- CAS: 161796-78-7
- CAS: 95510-70-6
- medchemexpress: HY-B0113A
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Ghazal Nabil, Yasmine H Ahmed, Omaima Ahmed, Selvia S Milad, Mohamed Hisham, Mohamed Rafat, Mohamed Atia, Aya A Shokry. Argel's stemmoside C as a novel natural remedy for mice with alcohol-induced gastric ulcer based on its molecular mechanistic pathways.
Journal of ethnopharmacology.
2024 Jun; 327(?):117970. doi:
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Journal of gastroenterology and hepatology.
2024 Apr; 39(4):658-666. doi:
10.1111/jgh.16471. [PMID: 38251791] - N J Menzies-Gow, T Shurlock. The effect of feeding a commercial feedstuff on gastric squamous gastric disease (ESGD) healing and prevention of recurrence.
Journal of equine veterinary science.
2024 Feb; 133(?):105015. doi:
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Scientific reports.
2024 01; 14(1):1699. doi:
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PloS one.
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Clinics and research in hepatology and gastroenterology.
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2022 Dec; 47(23):6320-6332. doi:
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Journal of the science of food and agriculture.
2022 Dec; 102(15):7030-7038. doi:
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Medicine.
2022 Oct; 101(40):e30898. doi:
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Helicobacter.
2022 Oct; 27(5):e12922. doi:
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Atherosclerosis.
2022 10; 358(?):47-54. doi:
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Clinical and translational science.
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Biophysical chemistry.
2022 06; 285(?):106809. doi:
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Mikrochimica acta.
2022 05; 189(6):225. doi:
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Biomedical chromatography : BMC.
2022 May; 36(5):e5343. doi:
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Journal of medicinal food.
2022 May; 25(5):513-522. doi:
10.1089/jmf.2020.0217. [PMID: 35561273] - Jatinder Kaur Mukker, George Dukes, Lisi Wang, Susanna Huh, Polyna Khudyakov, Mitsuhiro Nishihara, Chunlin Chen. Evaluation of the pharmacokinetics of trazpiroben (TAK-906) in the presence and absence of the proton pump inhibitor esomeprazole.
Clinical and translational science.
2022 05; 15(5):1281-1290. doi:
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Osteoarthritis and cartilage.
2022 04; 30(4):559-569. doi:
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Journal of food biochemistry.
2022 03; 46(3):e13804. doi:
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2022 Feb; 105(1):317-322. doi:
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Clinical pharmacology and therapeutics.
2022 02; 111(2):455-460. doi:
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Clinical pharmacology in drug development.
2022 02; 11(2):270-277. doi:
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Clinical pharmacology in drug development.
2022 01; 11(1):34-42. doi:
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2022; 16(?):619-634. doi:
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2021 Jul; 88(?):153584. doi:
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BMC infectious diseases.
2021 Jul; 21(1):642. doi:
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The FEBS journal.
2021 07; 288(13):4064-4080. doi:
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2021 May; 137(?):111345. doi:
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Medicine.
2021 Apr; 100(17):e25744. doi:
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2021 04; 64(8):5171-5184. doi:
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Physiological reports.
2021 04; 9(7):e14822. doi:
10.14814/phy2.14822. [PMID: 33818003] - Cengiz Güney, Kübra Açıkalın Coşkun, Yusuf Tutar. ATPase inhibition by omeprazole reveals role of heat shock proteins on testicular torsion.
Andrologia.
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Journal of pharmaceutical and biomedical analysis.
2021 Jan; 193(?):113668. doi:
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2021 Jan; 36(1):156-162. doi:
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Clinical pharmacology and therapeutics.
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Metabolic syndrome and related disorders.
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Medicine.
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
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Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
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Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine.
2020 09; 15(9):598-601. doi:
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International immunopharmacology.
2020 Aug; 85(?):106660. doi:
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British journal of clinical pharmacology.
2020 08; 86(8):1661-1666. doi:
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Scientific reports.
2020 06; 10(1):9547. doi:
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Frontiers of medicine.
2020 Feb; 14(1):43-50. doi:
10.1007/s11684-019-0706-8. [PMID: 31907860] - Sherif S Ebada, Nariman A Al-Jawabri, Fadia S Youssef, Amgad Albohy, Sa'ed M Aldalaien, Ahmad M Disi, Peter Proksch. In vivo antiulcer activity, phytochemical exploration, and molecular modelling of the polyphenolic-rich fraction of Crepis sancta extract.
Inflammopharmacology.
2020 Feb; 28(1):321-331. doi:
10.1007/s10787-019-00637-x. [PMID: 31482260] - Luis Francisco Calleja, Javier Alejandro Belmont-Díaz, Oscar Medina-Contreras, Héctor Quezada, Belem Yoval-Sánchez, Jesús Campos-García, José Salud Rodríguez-Zavala. Omeprazole as a potent activator of human cytosolic aldehyde dehydrogenase ALDH1A1.
Biochimica et biophysica acta. General subjects.
2020 01; 1864(1):129451. doi:
10.1016/j.bbagen.2019.129451. [PMID: 31678145] - Bhuvanachandra Pasupuleti, Vamshikrishna Gone, Ravali Baddam, Raj Kumar Venisetty, Om Prakash Prasad. Clinical Impact of Co-medication of Levetiracetam and Clobazam with Proton Pump Inhibitors: A Drug Interaction Study.
Current drug metabolism.
2020; 21(2):126-131. doi:
10.2174/1389200221666200218121050. [PMID: 32067615] - Zakia Belhadj, Bing He, Jijun Fu, Hua Zhang, Xueqing Wang, Wenbing Dai, Qiang Zhang. Regulating Interactions Between Targeted Nanocarriers and Mononuclear Phagocyte System via an Esomeprazole-Based Preconditioning Strategy.
International journal of nanomedicine.
2020; 15(?):6385-6399. doi:
10.2147/ijn.s258054. [PMID: 32922007] - Mei-Ling Wu, Yi-Ping Lin, Yan-Li Wei, Hong-Jian Du, Xiao-Qian Ying, Wen-Zhuang Tan, Bi-E Tang. Calycosin Influences the Metabolism of Five Probe Drugs in Rats.
Drug design, development and therapy.
2020; 14(?):429-434. doi:
10.2147/dddt.s236221. [PMID: 32099327] - Shan Lu, Daoshun Wu, Guibo Sun, Funeng Geng, Yongmei Shen, Jin Tan, Xiaobo Sun, Yun Luo. Gastroprotective effects of Kangfuxin against water-immersion and restraint stress-induced gastric ulcer in rats: roles of antioxidation, anti-inflammation, and pro-survival.
Pharmaceutical biology.
2019 Dec; 57(1):770-777. doi:
10.1080/13880209.2019.1682620. [PMID: 31696757] - Manal A Abbas, Yasser I Kandil, Ahmad M Disi, Sahar M Jaffal. Gastroprotective activity of Loranthus acaciae flower extract in a rodent model of ethanol-induced ulcer.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.
2019 Dec; 44(12):1283-1288. doi:
10.1139/apnm-2019-0166. [PMID: 31009579] - Hongyun Wang, Feng Shao, Xuemei Liu, Wen Xu, Ning Ou, Xianghong Qin, Fang Liu, Xuemei Hou, Haitang Hu, Ji Jiang. Efficacy, safety and pharmacokinetics of ilaprazole infusion in healthy subjects and patients with esomeprazole as positive control.
British journal of clinical pharmacology.
2019 11; 85(11):2547-2558. doi:
10.1111/bcp.14076. [PMID: 31332820] - Amy Fakhry Boushra, Asmaa Mohammed Elsayed, Noha Abdellatif Ibrahim, Maha Khaled Abdelwahed, Eman Ibrahim Ahmed. A comparative study on the possible protective effect of esomeprazole, spirulina, wheatgrass on indomethacin-induced gastric ulcer in male albino rats.
Molecular biology reports.
2019 Oct; 46(5):4843-4860. doi:
10.1007/s11033-019-04933-1. [PMID: 31297714] - Cüneyt Türkeş. A potential risk factor for paraoxonase 1: in silico and in-vitro analysis of the biological activity of proton-pump inhibitors.
The Journal of pharmacy and pharmacology.
2019 Oct; 71(10):1553-1564. doi:
10.1111/jphp.13141. [PMID: 31353473] - Sungpil Han, Hee Youn Choi, Yo Han Kim, Ji Yeon Nam, Bongtae Kim, Geun Seog Song, Hyeong-Seok Lim, Kyun-Seop Bae. Randomised clinical trial: safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple oral doses of tegoprazan (CJ-12420), a novel potassium-competitive acid blocker, in healthy male subjects.
Alimentary pharmacology & therapeutics.
2019 10; 50(7):751-759. doi:
10.1111/apt.15438. [PMID: 31437865] - Jie Ying, Liu-Cheng Li, Cui-Yun Wu, Zhen-Wei Yu, Lian-Di Kan. The status of proton pump inhibitor use: a prescription survey of 45 hospitals in China.
Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva.
2019 Oct; 111(10):738-743. doi:
10.17235/reed.2019.6155/2019. [PMID: 31373505] - Mahmoud M Sebaiy, Wafaa S Hassan, Mostafa E Elhennawy. Developing a High-Performance Liquid Chromatography (HPLC) Method for Simultaneous Determination of Oxytetracycline, Tinidazole and Esomeprazole in Human Plasma.
Journal of chromatographic science.
2019 Aug; 57(8):724-729. doi:
10.1093/chromsci/bmz046. [PMID: 31251331] - Ryohkan Funakoshi, Yukana Tomoda, Toshiyuki Kudo, Kenichi Furihata, Hiroyuki Kusuhara, Kiyomi Ito. Effects of proton pump inhibitors, esomeprazole and vonoprazan, on the disposition of proguanil, a CYP2C19 substrate, in healthy volunteers.
British journal of clinical pharmacology.
2019 07; 85(7):1454-1463. doi:
10.1111/bcp.13914. [PMID: 30845361] - Bo-Yi Jia, Chun-E Xie, Zhi-Bin Wang, Wen-Jing Pei, Xiao-Hong Li, Lei Shi, Jia-Li Liu, Ya-Fei Han, Xiang Tan, Pang-Hua Ding, Zhong-Mei Sun, Wen-Jing Yuan, Jun-Xiang Li. The effect of Heweijiangni-decoction on esophageal morphology in a rat model of OVA-induced visceral hypersensitivity followed by acid exposure.
Cellular and molecular biology (Noisy-le-Grand, France).
2019 Jun; 65(5):73-78. doi:
10.14715/cmb/2019.65.5.12. [PMID: 31304910] - Jed W Fahey, Kristina L Wade, Katherine K Stephenson, Anita A Panjwani, Hua Liu, Grace Cornblatt, Brian S Cornblatt, Stacy L Ownby, Edward Fuchs, Walter David Holtzclaw, Lawrence J Cheskin. Bioavailability of Sulforaphane Following Ingestion of Glucoraphanin-Rich Broccoli Sprout and Seed Extracts with Active Myrosinase: A Pilot Study of the Effects of Proton Pump Inhibitor Administration.
Nutrients.
2019 Jun; 11(7):. doi:
10.3390/nu11071489. [PMID: 31261930] - Hosam O Elansary, Tarek K Zin El-Abedin. Omeprazole alleviates water stress in peppermint and modulates the expression of menthol biosynthesis genes.
Plant physiology and biochemistry : PPB.
2019 Jun; 139(?):578-586. doi:
10.1016/j.plaphy.2019.04.018. [PMID: 31030025] - Hai-Bo He, Xiao-Qin Li, Xiao-Mei Li, Yu-Min He, Hui-Lin Qin, Yong-Feng Zhang, Xing-Jun Xiong, Jun-Zhi Wang, Kun Zou. [Therapeutic effect of total triterpenoids of Chaenomeles speciosa combined with omeprazole on gastric ulcer induced by indomethacin in rats].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2019 Jun; 44(11):2338-2347. doi:
10.19540/j.cnki.cjcmm.20190320.404. [PMID: 31359661] - Yi-Sing Shih, Chang-Hai Tsai, Tsai-Chung Li, Cheng-Ju Yu, Jen-Wei Chou, Chun-Lung Feng, Kun-Teng Wang, Hsueh-Chou Lai, Ching-Liang Hsieh. Effect of wu chu yu tang on gastroesophageal reflux disease: Randomized, double-blind, placebo-controlled trial.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2019 Mar; 56(?):118-125. doi:
10.1016/j.phymed.2018.09.185. [PMID: 30668332] - Do-Hyun Seo, Jong-Bok Lee, Ji-Hye Hwang, Jong-Woo Jeong, Gun-Ho Song, Tae-Sung Koo, Kyoung-Won Seo. Pharmacokinetics and pharmacodynamics of intravenous esomeprazole at 2 different dosages in dogs.
Journal of veterinary internal medicine.
2019 Mar; 33(2):531-535. doi:
10.1111/jvim.15383. [PMID: 30548689] - Karen E Hansen, Jeri W Nieves, Sai Nudurupati, David C Metz, Maria Claudia Perez. Dexlansoprazole and Esomeprazole Do Not Affect Bone Homeostasis in Healthy Postmenopausal Women.
Gastroenterology.
2019 03; 156(4):926-934.e6. doi:
10.1053/j.gastro.2018.11.023. [PMID: 30445008] - Dong-Min Yi, Tao-Tao Yang, Shuai-Heng Chao, Ya-Xin Li, Ying-Lei Zhou, Hai-Hui Zhang, Ling Lan, Yu-Wei Zhang, Xue-Mei Wang, Yan-Rui Zhang, Jian Li, Song-Ze Ding. Comparison the cost-efficacy of furazolidone-based versus clarithromycin-based quadruple therapy in initial treatment of Helicobacter pylori infection in a variable clarithromycin drug-resistant region, a single-center, prospective, randomized, open-label study.
Medicine.
2019 Feb; 98(6):e14408. doi:
10.1097/md.0000000000014408. [PMID: 30732192] - Toshiaki Shimizu, Yoshiko Nakayama, Eizaburo Ishii, Shinobu Ida, Tomoki Satou, Daisuke Tokuhara, Katsuhiro Arai, Masahiro Nii, Hans Rydholm, Toshitaka Yajima. Oral esomeprazole in Japanese pediatric patients with gastric acid-related disease: Safety, efficacy, and pharmacokinetics.
Pediatrics international : official journal of the Japan Pediatric Society.
2019 Jan; 61(1):87-95. doi:
10.1111/ped.13733. [PMID: 30422368] - Chen Cheng, Jianchang Qian, Zhe Wang, Wanshu Li, Chengke Huang, Mengchun Chen, Yaoyao Dong, Lejing Lian, Wei Sun. Influences of Corydalis decumbens on the Activities of CYP450 Enzymes in Rats with a Cocktail Approach.
BioMed research international.
2019; 2019(?):9614781. doi:
10.1155/2019/9614781. [PMID: 30800683] - Dasohm Kim, Min Soo Park, Byung Won Yoo, Taegon Hong, Shin Jung Park, Choon Ok Kim. The safety, pharmacodynamics, and pharmacokinetics of immediate-release formulation containing esomeprazole 20 mg/sodium bicarbonate 800 mg in healthy adult male.
Drug design, development and therapy.
2019; 13(?):3151-3159. doi:
10.2147/dddt.s212491. [PMID: 31564831] - Eunwoo Kim, Anhye Kim, Sojeong Yi, Yu Kyong Kim, Seong Bok Jang, Hae Mi Byun, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee. Effect of food on the pharmacokinetics of YH4808, a potassium-competitive acid blocker, after single- and multiple-oral dosing in healthy subjects.
European journal of clinical pharmacology.
2018 Oct; 74(10):1261-1272. doi:
10.1007/s00228-018-2502-9. [PMID: 29907887] - Antonio Lima Braga, Ag-Anne Pereira Melo de Meneses, José Victor de Oliveira Santos, Antonielly Campinho Dos Reis, Rosália Maria Tôrres de Lima, Ana Maria Oliveira Ferreira da Mata, Márcia Fernanda Correia Jardim Paz, Leane Brunelle Dos Santos Alves, Subrata Shaw, Shaikh Jamal Uddin, Razina Rouf, Asish Kumar Das, Shrabanti Dev, Manik Chandra Shil, Jamil A Shilpi, Ishaq N Khan, Muhammad Torequl Islam, Eunüs S Ali, Mohammad S Mubarak, Siddhartha Kumar Mishra, João Marcelo de Castro E Sousa, Ana Amélia de Carvalho Melo-Cavalcante. Toxicogenetic study of omeprazole and the modulatory effects of retinol palmitate and ascorbic acid on Allium cepa.
Chemosphere.
2018 08; 204(?):220-226. doi:
10.1016/j.chemosphere.2018.04.021. [PMID: 29656158] - Takashi Okamoto, Shogo Takatani, Yoshiteru Noutoshi, Hiroyasu Motose, Taku Takahashi. Omeprazole Enhances Mechanical Stress-Induced Root Growth Reduction in Arabidopsis thaliana.
Plant & cell physiology.
2018 Aug; 59(8):1581-1591. doi:
10.1093/pcp/pcy131. [PMID: 30011034] - Shimaa M Elshazly, Dalia M Abd El Motteleb, Islam A A E-H Ibrahim. Hesperidin protects against stress induced gastric ulcer through regulation of peroxisome proliferator activator receptor gamma in diabetic rats.
Chemico-biological interactions.
2018 Aug; 291(?):153-161. doi:
10.1016/j.cbi.2018.06.027. [PMID: 29944876] - Sook Jin Seong, Woo Youl Kang, Jae-Kyung Heo, Jungjae Jo, Won Gu Choi, Kwang-Hyeon Liu, Sangkyu Lee, Min-Koo Choi, Yong-Hae Han, Hye Suk Lee, Boram Ohk, Hae Won Lee, Im-Sook Song, Young-Ran Yoon. A Comprehensive In Vivo and In Vitro Assessment of the Drug Interaction Potential of Red Ginseng.
Clinical therapeutics.
2018 08; 40(8):1322-1337. doi:
10.1016/j.clinthera.2018.06.017. [PMID: 30078466] - J Sunwoo, J Oh, S J Moon, S C Ji, S H Lee, K-S Yu, H S Kim, A Lee, I-J Jang. Safety, tolerability, pharmacodynamics and pharmacokinetics of DWP14012, a novel potassium-competitive acid blocker, in healthy male subjects.
Alimentary pharmacology & therapeutics.
2018 07; 48(2):206-218. doi:
10.1111/apt.14818. [PMID: 29863280] - I-Fang Hsin, Shao-Jung Hsu, Chiao-Lin Chuang, Teh-Ia Huo, Hui-Chun Huang, Fa-Yauh Lee, Hsin-Ling Ho, Shu-Yu Chang, Shou-Dong Lee. The effects of proton pump inhibitor on hepatic vascular responsiveness and hemodynamics in cirrhotic rats.
Journal of the Chinese Medical Association : JCMA.
2018 Jul; 81(7):585-592. doi:
10.1016/j.jcma.2018.01.011. [PMID: 29780000] - Wangda Zhou, Trevor N Johnson, Khanh H Bui, S Y Amy Cheung, Jianguo Li, Hongmei Xu, Nidal Al-Huniti, Diansong Zhou. Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children.
Clinical pharmacology and therapeutics.
2018 07; 104(1):188-200. doi:
10.1002/cpt.905. [PMID: 29027194] - Amani N Shafik, Mahmoud A Khattab, Ahmed H Osman. Magnesium sulfate versus esomeprazole impact on the neonates of preeclamptic rats.
European journal of obstetrics, gynecology, and reproductive biology.
2018 Jun; 225(?):236-242. doi:
10.1016/j.ejogrb.2018.05.004. [PMID: 29758543] - Tayyar Alp Ozkan, Nihat Karakoyunlu, Reyhan Polat, Gülistan Sanem Sarıbaş, Nevzat Can Şener, Seyda Özdemir, Kevser Peker, Dilek Ünal, Can Tuygun. An evaluation of the protective effect of esomeprazole in an experimental model of renal ischemia-reperfusion.
International urology and nephrology.
2018 Feb; 50(2):217-223. doi:
10.1007/s11255-017-1775-8. [PMID: 29280047] - Jun Nishikawa, Ayumu Hosokawa, Mayo Fuchino, Shunsuke Takatori, Masaya Iwamoto, Yoshiro Kashii, Tadashi Bando, Tetsuro Shimizu, Masami Minemura, Toshiro Sugiyama. [Rhabdomyolysis associated with long-term treatment of esomeprazole].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology.
2018 ; 115(3):299-304. doi:
10.11405/nisshoshi.115.299. [PMID: 29526982] - Teppei Okamoto, Shingo Hatakeyama, Shogo Hosogoe, Yoshimi Tanaka, Kengo Imanishi, Toru Takashima, Fumitada Saitoh, Tadashi Suzuki, Chikara Ohyama. Proton pump inhibitor as an independent factor of progression of abdominal aortic calcification in patients on maintenance hemodialysis.
PloS one.
2018; 13(7):e0199160. doi:
10.1371/journal.pone.0199160. [PMID: 29969455] - Heba M Eltahir, Maiiada H Nazmy. Esomeprazole ameliorates CCl4 induced liver fibrosis in rats via modulating oxidative stress, inflammatory, fibrogenic and apoptotic markers.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Jan; 97(?):1356-1365. doi:
10.1016/j.biopha.2017.11.028. [PMID: 29156525] - Hsin Tian, Yanyan Xu, Jiayan Wang, Weiqiang Tian, Jian Sun, Tao Zhang, Qingyun Zhou, Chuxiao Shao. Effects of Plasma Albumin on the Pharmacokinetics of Esomeprazole in ICU Patients.
BioMed research international.
2018; 2018(?):6374374. doi:
10.1155/2018/6374374. [PMID: 30643812] - Jia Sun, Yuan Lu, Yueting Li, Jie Pan, Chunhua Liu, Zipeng Gong, Jing Huang, Jiang Zheng, Lin Zheng, Yongjun Li, Ting Liu, Yonglin Wang. Influence of Shenxiong Glucose Injection on the Activities of Six CYP Isozymes and Metabolism of Warfarin in Rats Assessed Using Probe Cocktail and Pharmacokinetic Approaches.
Molecules (Basel, Switzerland).
2017 Nov; 22(11):. doi:
10.3390/molecules22111994. [PMID: 29156621] - Ran Liu, Pei Li, Jie Xiao, Yidi Yin, Zheng Sun, Kaishun Bi, Qing Li. A fast, sensitive, and high throughput method for the determination of esomeprazole in dog plasma by UHPLC-MS/MS: Application to formulation development of the compound preparation of esomeprazole.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Nov; 1068-1069(?):352-357. doi:
10.1016/j.jchromb.2017.11.002. [PMID: 29128277] - Xiao Ma, Cheng-Wei Tang, Zhi-Yin Huang, Ming-Guang Zhang, Fang Liu, Chun-Hui Wang, Rui Wang, Huan Tong, Ling Liu. [Effect of Proton Pump Inhibitors on Severe Acute Pancreatitis--a Prospective Randomized Trial].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition.
2017 Nov; 48(6):933-936. doi:
NULL. [PMID: 29260533] - Shumin Qin, Keer Huang, Zhigang Fang, Jinjin Yin, Ruwei Dai. The effect of Astragaloside IV on ethanol-induced gastric mucosal injury in rats: Involvement of inflammation.
International immunopharmacology.
2017 Nov; 52(?):211-217. doi:
10.1016/j.intimp.2017.09.011. [PMID: 28942222] - Slimen Selmi, Kais Rtibi, Dhekra Grami, Hichem Sebai, Lamjed Marzouki. Protective effects of orange (Citrus sinensis L.) peel aqueous extract and hesperidin on oxidative stress and peptic ulcer induced by alcohol in rat.
Lipids in health and disease.
2017 Aug; 16(1):152. doi:
10.1186/s12944-017-0546-y. [PMID: 28806973]
